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Preparing for the Journey Using the Tools of the TrailblazersSession PM2, March 5, 2018

Lesley Anderson, Director, Business Development

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Lesley Anderson, MPIA, PMP

Has no real or apparent conflicts of interest to report.

Conflict of Interest

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Lesley E. Anderson, MPIA, PMP

• Leads the operational integration and business development of Inova Genomics Laboratory testing within the Inova Health System, including:

– Test implementation, service expansion, financial performance, revenue collection strategies, EMR integration, regulatory alignment

• Previously, involved with multiple clinical, operational, and education-related services for healthcare:

– Project management implementation at the American Society for Radiation Oncology (ASTRO), followed by enterprise-wide project management for the Inova Health System

– Director of Matching Services, overseeing the front line operations and growth of the National Resident Matching Program (NRMP), a.k.a. The Match

– More than a decade of oversight of data and information systems to support benchmarking and quality improvement at the Children’s Hospital Association

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• Not-for-profit healthcare system serving more

than 2M people each year in Northern Virginia

• Network of 5 hospitals, outpatient services and

facilities, primary and specialty care practices, and

health and wellness initiatives

• Developing 115 acre campus:

Inova’s Center for Personalized Health

– “Omics” & Bioinformatics Research & Integration

– Inova Translational Medicine Institute (ITMI)

– Inova Schar Cancer Institute

– Discovery & Innovation Hub

– University & Commercial Partnerships

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Inova Genomics Laboratory• 2014: Inova Genomics Laboratory launched, CLIA certified

• 2016: Inova launches MediMap®, a pharmacogenomic test for newborns

• 2017: CAP certification received

– MediMap Plavix® Rapid Test launched

– Consumer-directed MediMap testing started

– MediMap Mind, ADHD, Plus panel tests launched

– Pilot PGx study launched in Primary Care clinic

– Inova partners with Veritas Genetics to offer MyMap™ whole genome testing

• Over 13,000 pharmacogenomic tests resulted 2016

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Questions

Lesley E. Anderson, MPIA, PMP

Director, Business Development

Inova Genomics Lab

Inova Health System

3300 Gallows Road, Claude Moore Bld, 2nd Fl.

Falls Church, VA 22042

Lesley.Anderson@inova.org

inova.org/YourRoadmap

www.linkedin.com/in/lesleyeanderson

T 703-776-7951

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Preparing for the Journey Using the Tools of the TrailblazersSession PM2, March 5, 2018

Sandy Aronson

Executive Director of Information Technology

Partners HealthCare Personalized Medicine

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Sandy Aronson

• My group receives funding from Persistent to develop open source SMART on FHIR apps and platform functionality to support this development

• My employer, Partners HealthCare, receives royalties on the sale of GeneInsight software

Conflict of Interest

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Machine

Learning Genomics

Connected

Devices

Intense Cost

Pressure

Health System

Primed for Radical

Disruptions

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Idea on How to

Radically

Improve Care

Research and

Analysis

Validate and

Put into Use

Within Partners

Distribute and

Build Networks

to Continuously

Learn

Ch

asm

Ch

asm

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Our Group’s Trajectory

Clinical Genetic Lab Support

Clinician Use of Genetics

Cross-Institutional Near Real-time Sharing of

Variant Interpretations

App Based IT Interventions to

Fundamentally Improve Clinical Decision Making Using Multi-Dimensional Data Including Genetics

Interinstitutional Federated Continuous Learning Infrastructure Focused on Targeted

Clinical Process Improvements

Past Development Present Focus Future Goal

Expanding Scope of Learning Infrastructure

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Questions

Sandy Aronson, ALM, MA

Executive Director of IT

Partners HealthCare Personalized Medicine

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Preparing for the Journey Using the Tools of the TrailblazersSession PM2, March 5, 2018

Abel Kho, MD, MS, FACMIDirector, CHiP; Associate Professor, Feinberg School of Medicine, Northwestern University

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Abel Kho MD, MS, FACMI

Co-founder of Health DataLink LLC

Conflict of Interest

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All of Us Research Program•Mission

• Accelerate health research and medical breakthroughs, enabling individualized prevention, treatment, and care for all of us.

•How

• Collect genomic and EHR data for 1+ million participants

•http://allofus.nih.govPage

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16 16

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All of Us Research Program - Components

Data & Research Center (DRC)

Biobank

Health Care Provider Organizations (HPO)

Participant Technology

Systems Center

Participant Center

OMOP

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Source: https://www.ohdsi.org/data-standardization/

Site 1 Site 3 Site …Site 2 Site 4 Site 35

Transformation of Source Data to OMOP Common Data Model

Data Quality Checks

All of Us

OMOP CDM

HP

OD

RC

All of Us Aggregating EHR Data

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Questions

Abel Kho, MD, MS, FACMI

Director, CHiP

Associate Professor

Feinberg School of Medicine

Northwestern University

akho@nm.org

Healthinformationforall.org

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Preparing for the Journey Using the Tools of the Trailblazers

• Lesley Anderson | Director, Business Development, INOVA Genomics Lab

• Sandy Aronson | Executive Director of Information Technology, Partners HealthCare Personalized Medicine

• Abel Kho | Director, Center for Health Information Partnerships, Northwestern University