PrEP Implementation and Safety Studies

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PrEP Implementation and Safety Studies Andrew Mujugira, MBChB, MSc, MPH, PhD, MACE Senior Research Scientist Infectious Diseases Institute, Makerere University PEPFAR Uganda Science Summit Translating Research into Programs for 2020 and Beyond January 13-14, 2020 Kampala Uganda

Transcript of PrEP Implementation and Safety Studies

Page 1: PrEP Implementation and Safety Studies

PrEP Implementation and Safety Studies

Andrew Mujugira, MBChB, MSc, MPH, PhD, MACE

Senior Research Scientist

Infectious Diseases Institute, Makerere University

PEPFAR Uganda Science SummitTranslating Research into Programs for 2020 and Beyond

January 13-14, 2020Kampala Uganda

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PrEP Implementation and Safety Studies

PEPFAR Uganda Science Summit January 2020

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PrEP Implementation and Safety Studies

PEPFAR Uganda Science Summit January 2020

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From research to public health practice

PEPFAR Uganda Science Summit January 2020

PartnershipsMinistry of HealthKCCAWakiso DistrictMARPITASOWONETHA

Communities and Collaborations

Peer recruitersYoung womenSex workersYoung menTransgender

Community Advisory Group

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Implications for National HIV Response

PEPFAR Uganda Science Summit January 2020

1) Integration of PrEP and ART delivery for serodiscordant couples in public health clinics

2) Estimate programmatic costs of providing integrated PrEP and ART to HIV serodiscordant couples

3) Effectiveness of peer-delivered combination HIV prevention to hidden key populations

4) HIV self-testing and PrEP to increase prevention uptake by sex workers, their clients and male partners of HIV positive pregnant women

5) Effect of concurrent use of PrEP and DMPA contraception on bone health of adolescent girls and young women

6) Alignment of PrEP use with HIV risk among young women and their male partners

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Acknowledgments and Contact Info

PEPFAR Uganda Science Summit January 2020

Investigators• Infectious Diseases Institute (Andrew Mujugira, Timothy Muwonge)• University of Washington (Connie Celum, Renee Heffron, Monica Sharma, Jared Baeten)• MGH/Harvard (Jessica Haberer, Norma Ware, Monique Wyatt)

Funders• U.S. National Institutes of Health (grants R01 HD089843, R01 MH113434, R01 MH110296,

R34 MH121084, R21 HD098923, K43 TW010695, K01 MH115789)• University of Washington/Fred Hutch (grant P30 AI027757)

Gilead Sciences (FTC/TDF donation)

Contact: Andrew Mujugira ([email protected], 0754 173 225)

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OK to share slides with attendees after Summit?

• Yes

PEPFAR Uganda Science Summit January 2020