PrEP Implementation and Safety Studies
Transcript of PrEP Implementation and Safety Studies
PrEP Implementation and Safety Studies
Andrew Mujugira, MBChB, MSc, MPH, PhD, MACE
Senior Research Scientist
Infectious Diseases Institute, Makerere University
PEPFAR Uganda Science SummitTranslating Research into Programs for 2020 and Beyond
January 13-14, 2020Kampala Uganda
PrEP Implementation and Safety Studies
PEPFAR Uganda Science Summit January 2020
PrEP Implementation and Safety Studies
PEPFAR Uganda Science Summit January 2020
From research to public health practice
PEPFAR Uganda Science Summit January 2020
PartnershipsMinistry of HealthKCCAWakiso DistrictMARPITASOWONETHA
Communities and Collaborations
Peer recruitersYoung womenSex workersYoung menTransgender
Community Advisory Group
Implications for National HIV Response
PEPFAR Uganda Science Summit January 2020
1) Integration of PrEP and ART delivery for serodiscordant couples in public health clinics
2) Estimate programmatic costs of providing integrated PrEP and ART to HIV serodiscordant couples
3) Effectiveness of peer-delivered combination HIV prevention to hidden key populations
4) HIV self-testing and PrEP to increase prevention uptake by sex workers, their clients and male partners of HIV positive pregnant women
5) Effect of concurrent use of PrEP and DMPA contraception on bone health of adolescent girls and young women
6) Alignment of PrEP use with HIV risk among young women and their male partners
Acknowledgments and Contact Info
PEPFAR Uganda Science Summit January 2020
Investigators• Infectious Diseases Institute (Andrew Mujugira, Timothy Muwonge)• University of Washington (Connie Celum, Renee Heffron, Monica Sharma, Jared Baeten)• MGH/Harvard (Jessica Haberer, Norma Ware, Monique Wyatt)
Funders• U.S. National Institutes of Health (grants R01 HD089843, R01 MH113434, R01 MH110296,
R34 MH121084, R21 HD098923, K43 TW010695, K01 MH115789)• University of Washington/Fred Hutch (grant P30 AI027757)
Gilead Sciences (FTC/TDF donation)
Contact: Andrew Mujugira ([email protected], 0754 173 225)
OK to share slides with attendees after Summit?
• Yes
PEPFAR Uganda Science Summit January 2020