Pregnancy Complications - Whitney Lewis

45
Late Complications in Pregnancy Grand Rounds Presentation Whitney Lewis DO, MS

Transcript of Pregnancy Complications - Whitney Lewis

Late Complications in Pregnancy

Grand Rounds Presentation

Whitney Lewis DO, MS

Ca

rdio

va

scu

lar C

ha

ng

es

in P

reg

na

nc

y

UCC transfer for CP

25yo G3P2 39 wks, no PMH with acute onset of sharp, non-

radiating R sided chest pain PTA, SOB and LLE edema.

EKG: ST

VS: HR 110, RR 26, BP 108/76, Temp 36.8, SpO2 94%

Pulmonary Embolism

Leading cause of morbidity/mortality

High pretest probability of DVT/PE = HIGH RISK

Aortic Dissection

PTX

Pneumonia/URTI

ACS/UA

Esophageal Perforation

Pericarditis/Myocarditis

Pleuritis

Cardiac Tamponade

Pulmonary Embolism Management

1. 2.

High probability VQ scan

Positive CTPA

PE Treatment in Pregnancy

Heparin wt based LD/gtt

LMWH 1mg/kg q12hrs SQ

POD 4 Booth 32

19yo G1P0 black female at 36 wks, no PMH presents to the

ED s/p 3 minute GTC seizure with headache, MEG abd pain

and blurry vision.

VS: HR 100, RR 16, BP 160/115, Temp 37.3, SpO2 100%

POC Glucose 85

Elevated Blood Pressure in Pregnancy

1. Eclampsia:

Pre-eclampsia plus seizures and/or coma

2. Pre-eclampsia:

New onset HTN >140/90 mmHg and proteinuria or

end organ dysfunction >20 wks

Pre

-ec

lam

psia

Management

ABCs, IV, O2, monitor

Labs: CBC, CMP, coags, LDH, T&S

Imaging: MR/CT abd and pelvis, US, CT head

OB consult:

1. Nonsevere Pre-eclampsia

Serial BPs, US, bed rest

Management

2. Severe Pre-eclampsia

SBP 140-155 mmHg and DBP 90-105 mmHg

Tx: Labetalol, Hydralazine, Nifedipine, Nicardipine gtt

DOC ppx or Eclampsia Magnesium sulfate

Toxicity: Calcium gluconate

Continued seizures = benzos

DELIVERY per OB >34 wks

POD 2

28yo F G2P1 at 37 wks, no PMH presents with painless bright

red vaginal bleeding.

VS: HR 90, RR 14, BP 110/70, Temp 37.1, SpO2 99%

DDx 3rd Trimester Hemorrhage

3rd Trimester Hemorrhage

PAINLESS

Placenta Previa

Vasa Previa

PAINFUL

Placental Abruption

Uterine Rupture

Labor

Placenta Previa

Placenta implantation over cervix

PAINLESS BRIGHT RED VB and NONTENDER ABDOMEN

Vasa Previa

Fetal membranes over

internal os

PAINLESS BRIGHT RED VB and

NONTENDER ABDOMEN

Placental Abruption

Separation placenta from uterine wall

Etiology:

Traumatic

Spontaneous (cocaine, HTN, pre-eclampsia)

Physical examination

DARK RED VB

ABDOMINAL PAIN

• Uterine irritability fetal distress

Uterine rupture

Rare (prior c/s, trauma, HTN)

Physical examination:

VB

SEVERE ABDOMINAL PAIN

Loss of fetal station

Uterine defect

Management

ABCs, IVx2, O2, Monitor

NO BIMANUAL EXAMINATION

Labs: CBC, CMP, coags, T&S, fibrinogen, FDP

Imaging: US r/o previa does NOT r/o abruption, FAST

IVF, PRBCs/MTP, Rhogam

OB consult:

C/S delivery (>37 wks or unstable mother)

Expectant management

POD 1: WBPW from triage

38yo F, holding her abdomen in a wheelchair

screaming "no puedo.”

ED Delivery

ABCs, IV, O2, monitor

HPI: G&P's, prenatal care, complications

Precipitous delivery kit and Peds cart

OB and NICU consults

38yo F G8P8, SVD, placenta delivered, baby APGARs 9 and 10,

vaginal bleeding continues...

Postpartum Hemorrhage (PPH)

SVD >500 mL

IVx2, O2, monitor

Labs: CBC, CMP, coags, T&S, FDP, fibrinogen

IVF 1-2L LR, PRBCs/MTP

PPH

4 T's:

1. Tone

2. Tissue

3. Trauma

4. Thrombin

Tone: Uterine Atony

80% PPH

Boggy uterus

Management:

Bimanual uterine massage

DOC Oxytocin 20U in 1L @ 10mL/min

Tissue

Examine placenta

Management:

Manually explore uterus

Uterine packing or balloon tamponade

OR for exploration vs. IR embolization

Trauma

1. Lacerations

2. Uterine inversion

3. Uterine rupture

OB OR repair uterine defect

Thrombin

Coagulation disorders:

Hereditary

DIC, HELLP

Management:

Replace PRBCs, platelets, FFP, Cryo, Factors VIIa, VIII or IX

Postpartum Hemorrhage

Hemorrhagic Shock:

Signs of shock develop after 30% blood volume lost

CO maintained until Hgb <7 or HCT <20%

Management:

Give PRBCs if HCT < 25-30% with ongoing bleeding

Platelets <50,000 replace

Fibrinogen <100 mg/dL FFP, Cryo

PT/INR, PTT Cryo, recombinant factor VIIa, PCC

POD 3, Level 1 Trauma

23yo pregnant F BIB EMS s/p front-end

MVC at 50 mph, restrained driver, no

airbag deployment and pt not ambulatory on the scene

Anatomic Changes

Uterus:

>12wks intra-abdominal

>20 wks fundus at umbilicus

> 24wks viable

Uterine rupture and placental abruption:

5% minor and 50% major blunt trauma

incidents

4-5x incidence FMH

Injured uterus contractions, preterm

labor and pregnancy loss

Management of Abdominal Trauma

in Pregnancy

IVx2, O2, monitor, trauma labs, 1L LR, Tetanus and Rhogam prn

L tilt 15-30o

1o Survey:

Airway

Breathing

Circulation

Disability: GCS

Exposure

FAST

Critical Care in the Pregnant Patient

Intubation:

Dec FRV 25%

Increased risk aspiration

Respiratory alkalosis

Chest tubes:

Diaphragm 4cm higher

3rd or 4th ICS

Management of Abdominal Trauma

in Pregnancy

2o Survey:

Head to toe exam

Speculum exam

Fetal monitoring

OB and Trauma surgery consults

Imaging and

Disposition

Imaging:

CXR/PXR

Selective scanning with shielding

Mother and viable fetus STABLE 4hrs monitoring

3 contractions/hr, uterine TTP, VB, ROM obs 24hrs

Mother STABLE and fetus

UNSTABLE

optimize maternal condition,

C/S >24 wks

Mother and fetus UNSTABLE attend mother, +FAST= OR ex-

lap vs. C/S

Perimortem Caesarian Section

Perimortem C/S maternal cardiac arrest and viable fetus

Continue ATLS/ACLS

<5 min = best prognosis, 98% neuro intact

0% survival >25 min

Equipment: scalpel, Mayo scissors, retractors, towels, chromic

#0 or 1 and needle holder

Pe

rimo

rtem

Ca

esa

rian

Se

ctio

n

Questions?

References: pictures

community. babycenter.com

community.freescale.com

http://http://en.wikipedia.org/wiki/Coagulation#mediaviewer/File:Coagulation_full.svg

www.brooksidepress.org/Products/Obstetric_and_Newborn_Care_1/lesson_5_Section_1.htm

http://radiology.med.miami.edu/documents/2009Lungs.pdf

http://accessmedicine.mhmedical.com.foyer.swmed.edu/ViewLarge.aspx?figid=39621558

http://accessmedicine.mhmedical.com.foyer.swmed.edu/content.aspx?bookid=351&sectionid=39619709

http://thedefinitionofnerd.blogspot.com/2013/08/life-matters-true-blood-pros-and-cons.html

www.theamericanmama.com

www.webmd.boots.com

http://accessmedicine.mhmedical.com.foyer.swmed.edu/book.aspx?bookid=351

www.merkmanuals.com

http://mdcurrent.in/primary-care/practical-advice-on-preventing-maternal-death-due-to-postpartum-hemorrhage/

www.medpagetoday.com

http://www.trauma.org/archive/thoracic/CHESTdrain.html

www.wisegeek.com

References: sources

American College of Surgeons Committee on Trauma. ATLS, Student Course Manual. 8th Ed.2008. Pgs 260-265.

Anderson J.M., and Etches D. (2007). Prevention and management of postpartum hemorrhage. American Family Physician. 75(6), 875-882.

Brown, Carlos MD. Trauma in Pregnancy. EM:RAP. January 2013.

Cunningham, F., Leveno, K., Bloom, S., Spong, C., Dashe, J. Williams Obstetrics, 24th Ed. McGraw-Hill Education, 2014. Chapter 47.

Knoop, Kevin, Stack, S., Storrow, A. The Atlas of Emergency Medicine, 3rd Ed. McGraw-Hill Companies, Inc, 2010. Chapter 10.

Marx, John MD, Hockberger, R. MD, Walls, R. MD. Rosens Emergency Medicine-Concepts and Clinical Practice 8th

Ed. Elsevier, 2013. Chapters 34, 37, 178, 179.

Orman, Rob, Jasumback, M. VQ in Pregnancy? A Rant and Response. EM:RAP. March 2011.

Orman, Rob. Klien, J. Chest Pain in Pregnancy. EM:RAP. December 2011.

Rivers, Carol M.D. Preparing For the Written Board Exam. Urogenital Emergencies. 6th Ed., Vol. 1. Ohio ACEP. 2011. Pgs 556-575.

Tintinalli, Judith E., J. Stephan Stapczynski, O. John Ma, David M. Cline, Rita K. Cydulka, Garth D. Meckler, The American College of Emergency Physicians. Tintinalli's Emergency Medicine: A Comprehensive Study Guide, 7th Ed. The McGrw-Hill Companies, Inc. 2011. Chapters 103-104.