Precellys homogenizers

Precellys 24Tissue homogenizer

Precellys 24 is an efficient, robust and high throughput homogenizer, capable of simultaneously handling up to 24 samples.

• High quality: robust, ergonomic and safe• Efficient: provides powerful 3D bead-beating while

maintaining total molecular integrity• Flexible: from soft to hard tissues / from low to high

throughput• Reproducible: more than a thousand validated

protocols available for users

+ Compatible with the only patented and efficient cooling option for sensitive samples

www.precellys.com

24x2ml

Effi cient and robust high-throughput homogenizer

PRECELLYS 24

Technical specifications

The Science of Lysing

CAPACITY

from 1 to 24 tubes of 2ml/0,5ml

SPEED RANGE

4000 – 6800 rpm by increment of 100rpm

PROGRAMS

5 presets programs

NUMBER OF CYCLES

from 1 to 3 cycles

TIME time of use per cycle: from 5s to 90s

pause between cycle: from 5s to 120s

SIZE L: 290mm, W: 375mm, H: 370mm

(600mm with opened lid)

WEIGHT

29,8 kg

NORMS

CE, FCC part 15

developed to be used in L3

laboratory

ELECTRICITY

100 - 230 VAC / 50-60 Hz

power:1 kVA

NOISE ‹ 70dB

PATENTED TECHNOLOGY

CATALOG NUMBER

03119.200.RD000

Precellys range Discover the other products of the Precellys range

Preserve your sensitive samples: ensure the combined yield and integrity of thermo-sensitive molecules by using the Cryolys cooling option!

Precellys 24-Dual for flexibility

Cryolys for sensitive

samples

Minilysfor personal use

Lysing Kits consumables

ANIMAL & HUMAN

MICRO-ORGANISMS

PLANT TISSUES

Precellys 24 for high throughputGrind and homogenize a wide range of biological samples with Precellys 24!

Designed for use in L3 laboratories, it is highly robust for daily use. The system enables the preparation of up to 24 biological samples from soft to hard tissue (animal & human tissue, plant tissue, microorganisms…) and has been validated on more than 1000 different samples: from brain, muscle and heart samples to very hard matter such as bones, hair and rice…

A figure-of-8 multi-directional motion gives a high energy level to the beads that grind up to 24 samples together in just a few seconds, at speeds ranging from 4000 rpm to 6800 rpm. Typical homogenization time is thus around 30 seconds. Samples are then ready for analysis using DNA, RNA analysis, PCR, Electrophoresis, Liquid Chromatography, Western Blot…

Precellys 24 - Quick User Mode

1. Load from one to twenty-four 2ml tubes 2. Position the patented system for quick and safe blocking

3. Set speed (4000 - 6800 rpm), time and cycle

DNARNADrugsProteins

4. 3D bead-beating: homogenization is achieved in just a few seconds

5. The same efficiency in each tube enables the liberation of cell components

6. In around 30 seconds, your sample is ready for analysis!

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1000 protocolsavailable on

www.precellys.comBERTIN TECHNOLOGIES BERTIN Corp. FRANCE MD, USAPhone: +33 139 306 169 Phone: +1 240 428 1047

[email protected]

Find your distributor on www.precellys.com

• Dual: 6x7ml or 12x2 (or 0,5ml) lysing tubes• Flexible: from 0,5µl to 7ml samples / from soft

to hard tissues• Efficient: provides powerful 3D bead-beating

motion while maintaining total molecular integrity• High quality: robust, ergonomic and safe

+ Compatible with the only patented and efficient cooling option for sensitive samples

www.precellys.com

6x7ml or 12x2ml

Tissue homogenizer

Precellys 24-Dual is an efficient & flexible tissue homogenizer, for medium-to-high-throughput routine process.

Precellys 24Dual


CAPACITY


from 1 to 6 tubes of 7ml

SPEED RANGE

4000 - 6500 rpm by increment of 100rpm

PROGRAMS

5 user presets

NUMBER OF CYCLES

from 1 to 3 cycles

TIME time of use per cycle: from 5s to 90s

pause between cycle: from 5s to 120s

SIZE L: 290mm, W: 375mm, H: 370mm

(600mm with opened lid)

WEIGHT

29,8 kg

NORMS

CE, FCC part 15

developed to be used in L3 laboratory

ELECTRICITY

100 - 230 VAC / 50-60 Hz

power:1 kVA

NOISE ‹ 70dB

PATENTED TECHNOLOGY

CATALOG NUMBER

03119.200.RD010

Effi cient and f exible homogenizer


Precellys 24-Dual for greater fexibilityExpand your Precellys 24 experience with the access to 7ml lysing tubes with Precellys 24-Dual!Precellys 24-Dual is a biological sample homogenizer for medium throughput (up to 12 samples) and a diverse range of biological samples (several different tube formats according to the size and quantity of your samples).The system enables sample preparation in 0.5ml, 2ml or 7ml tubes and biological samples from soft to hard tissues / from 1mg to 5000 mg. A figure-of-8 multi-directional motion gives a high energy level to the beads that grind up to 12 samples together in just a few seconds, at speeds ranging from 4000 to 6500 rpm. Typical homogenization time is thus around 30 seconds. Samples are then ready for analysis using DNA, RNA analysis, PCR, Electrophoresis, Liquid Chromatography, Western Blot…


Preserve your sensitive samples: ensure the combined yield and integrity of thermo-sensitive molecules by using the Cryolys cooling option!

PRECELLYS 24-DUAL

Precellys 24 for high throughput


samples

Minilysfor personal use


Precellys 24-Dual - Quick User Mode

DNARNADrugsProteins

1. Load from one to twelve 2ml tubes or from one to six 7ml tubes

4. 3D bead-beating: homogenization is achieved in just a few seconds

2. Position the patented system for quick and safe blocking

5. The same efficiency in each tube enables the liberation of cell components

3. Set speed (4000 - 6500 rpm), time and cycle


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[email protected]


• The only efficient and small homogenizerfor 3D bead beating

• Flexible & ready-to-use: a wide range of samples (type/volume) and parameters

• Convenient for personal use• Safe & easy-to-handle system• Small equipment footprint

www.precellys.com

1x7ml or 3x2ml

Minilys is a flexible and personal homogenizer for cell/sample disruption for daily lab workflow.

MinilysTissue homogenizer


CAPACITY


from 1 to 3 microtubes

1 tube of 7ml

SPEED RANGE

3000, 4000 or 5000 rpm

TIME from 5s to 240s

SIZE L: 180mm, W: 290mm, H: 380mm

WEIGHT

7.8kg

NORMS

CE, FCC part 15

ELECTRICITY

100 - 230 VAC / 50-60 Hz

power:1 kVA

NOISE ‹ 70dB

PATENTED TECHNOLOGY

CATALOG NUMBER

06404.200.RD000

Flexible and personal homogenizer


MINILYS Minilys is a small and compact homogenizer for fast hands-free disruption of a wide range of biological samples (prior to DNA, RNA, proteins or drug extraction) at a low throughput level. Flexible (0.5ml, 2ml, 7ml lysing tubes) and easy to handle, it is the only small homogenizer that works in 3D motion, following standard protocols and providing more homogeneous results. Moreover, Minilys is extremely budget-friendly.

Convenient for personal use Specially designed for low-throughput laboratory workfows and personal use, Minilys homogenizes 3 samples simultaneously in 0.5ml/2ml tubes or 1 sample in 7ml. Small and compact, Minilys requires minimal bench space in your laboratory.

Efficient & rapidMinilys offers the same bead-beating technology and extremely high quality as the Precellys homogenizer range, is the only small homogenizer on the market that disrupts samples using 3D motion and is by far the most efficient one.

Safe & easy-handlingMinilys ensures easy-handling and safe operations. Its innovative cut-out system automatically stops the operation if the lid is not firmly closed or is opened while running, thus providing additional safety guarantees for users.

Flexible & ready-to-useMinilys accommodates a wide range of sample types from animal & plant tissue to microorganisms.With 3 different speeds ranging from 3000 to 5000 rpm, Minilys can handle either low-velocity agitation or harsh homogenization. Detachable tube-holders are adapted to three volumes of lysing tubes (0,5ml, 2ml or 7ml), providing the flexibility to vary your sample size and volume.


MINILYS




samples


Minilys - Quick User Mode

1. Prepare your biological samples in 0.5, 2ml or 7ml tubes

2. Load between one and three 2ml or 7ml tubes


3. Set speed and time 4. 3D beat-beating: same efficiency in each tube enables the liberation of cell components.

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[email protected]


• Efficient cooling: before, during and after processing• Ideal for thermo-sensitive molecules: RNA, siRNA,

metabolites, enzymes, proteins…• Adjustable cooling fow rate• Powered by liquid nitrogen or dry ice

www.precellys.com

Cooling system for sensitive sample preparation

Cryolys coupled with Precellys

Cryolys is a patented cooling option to overcome the heat limitations of regular grinding and to protect thermo-sensitive molecules

Cryolys


AIR FLOW RATE SETTINGS

80, 100 or 120 litre/min

SIZEL: 430mm, W: 300mm, H: 300mm

WEIGHT

16 kg

NORMS CE

ELECTRICITY

100 - 230 VAC / 50-60 Hz

power: 2A

NOISE

‹ 70dB

PATENTED TECHNOLOGY

Lab requirement

Compressed air (lab network

or canister):

- Pressure: from 4 bars (5 PSI)

to 8 bars (116 PSI)

- Flow rate: up to 120 l/min (7,2

m3/h)

- Consumption (run time): 1l of

liquid nitrogen for 5 min / 1kg

of dry ice for 1,5h

CATALOG NUMBER

05068.200.RD000

Cooling system for sensitive sample preparation


CRYOLYS for sensitive samplesCryolys is the only patented cooling option that prevents the increase of temperature during lysing; it thus enhances the efficiency of molecular extraction, resulting in premium quality analysis, maintaining temperature at approximately 4°C before and during homogenization.It enables the extraction of stable RNA and native-state proteins. Cryolys is compatible with Precellys 24 and Precellys 24-Dual homogenizers.Cold air (-50°C) is sprayed around each tube so that the temperature during homogenization remains at around 4°C. A probe enables real-time monitoring of the temperature inside the lid, thus protecting sensitive molecules from degradation during sample preparation. Achieve higher yield, greater quality and increased functionality Prevent enzymes from becoming active Retain 100% active proteins


Cryolys - Quick User Mode

CRYOLYS



Minilys for personal use


Temp. in tubesTemp. in tube w/CryolysPrecellys Run on/Off

Temperature Profile with Cryolys Option 6800rpm, 3x30s, 30s breaks, Compressed Air Flow rate: 120L/min

Tem

péra

ture

(C°)

90

80

70

60

50

40

30

20

10

0

0 0,5 1 1,5 2 2,5 3 3,5 4Time (min)

+85°C inside tubes

without Cryolys

With Cryolys, your

sensitive samples are preserved !

1. Compressed air passes through liquid nitrogen or dry-ice inside Cryolys

2. Cold compressed air is sprayed into the specially-adapted Precellys lid

3. Each sample is cooled and temperature sensitive molecules are retained in their native state

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[email protected]


• More than 15 references for soft samples to hard samples

• 0,5ml – 2ml – 7ml ready-to-use tubes• Wide range and mix of beads for optimized results• Full range of ceramic beads

www.precellys.com

0,5ml tubes2ml tubes 7ml tubes

Precellys Lysing Kits are prefilled tubes with specific beads and are suitable for use with all biological samples prepared for DNA, RNA, protein or drug extraction.

PrecellysLysing kitsfor tissue homogenizer


www.precellys.com

Animal and Human tissue homogenization Brain, liver, heart, muscle, skin, kidney, lung, spleen, colon,faeces etc. Also pulverization of difficult tissue samples such asbones, hair, cartilage, etc.Whole organs can even be prepared thanks to 7ml Lysing Kits.

Plant tissue grinding Leaves oats, tomato seeds, cotton, soil etc.Also pulverization of hard materials such as seeds, roots, rice etc.Large samples can also be prepared thanks to 7ml Lysing Kits.

Micro-organism lysing Small beads facilitate the crushing of micro-organism walls.Yeast, fungi, spores, mould, bact. gram+/gram-, mycobacteria, cyanobacteria, algae etc.0.5ml Lysing Kits are especially suited to small sample amounts.


QUANTITY OF TUBES PER KIT: 50

TUBES & CAPS MATERIALS:

Polypropylen Co-Polymered

TEMPERATURE RANGE OF USE:

-80°C to 100°C

AUTOCLAVE: standard procedure

CHEMICAL COMPATIBILITY: compatible

with most of extraction buffer (Acid

Phenol, Guanidine thiocyanate,

acetonitril etc.)

LOADING CAPACITY 0.5ml : from 1mg to

30mg tissue or 5µL to 200µL culture

LOADING CAPACITY 2ml : from 30mg

to 1g tissue or 200µL to 1.6ml culture

LOADING CAPACITY 7ml : from 30mg

to 5g tissue or 200µL to 6ml culture

COMPATIBLE WITH PRECELLYS 24,

PRECELLYS 24-DUAL, CRYOLYS

AND MINILYS.

A complete range for biological samples preparation

PRECELLYS LYSING KITS The Science of Lysing

Enjoy all the benefits of Precellys’ powerful bead-beating technology with the 15 available references of Precellys Lysing Kits! Precellys Lysing Kits are robust tubes prefilled with high quality beads and manufactured under clean-room environment.Optimize your preparation of biological samples: animal tissue, human tissue, plant tissue, microorganisms… whatever the precious sample you wish to prepare, find a suitable Precellys Lysing kit from the 15 available references: choose the right tube size (0.5ml, 2ml or 7ml), bead type / diameter (ceramic, glass, stainless steel …) and you will be sure to obtain excellent DNA, RNA, Protein and Drug recovery!

Log on now to www.precellys.com to find the most suitable lysing kit for your sample!

Save time and improve your lab practices by following tried & tested scientificpublications: use our web-based Application Center to find the right Lysing Kit for your sample: just enter your sample name and get access to examples, lysing kits and protocols that current Precellys’ users are already using!



Cryolys for sensitive sample

Minilys for personal use

Precellys range Precellys Lysing Kits are specially designed for use with the entire Precellysrange:

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Precellys LYSING KITS



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Precellys homogenizers

Technology

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