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Anatomic LocalizationEvery anatomic location has unique clinical signsNeurology examination tests for those clinical signsYou must perform and interpret the examination properly to have it help!
Rostral to the Foramen MagnumCerebrum/telencephalonThalmus/diencephalonMidbrain/mesencephalonPons/metencephalonMedulla oblongata/myelencephalonCerebellum/part of metencephalon
Lesion LocalizationTelencephalon/Diencephalon
Mentation changes: depression, dementia, stupor, comaSeizures (ALWAYS!!!)Basal Ganglia: LIMITED (cerebrospinal tracts) motor to limbs.
• Horse: lips, face• Dog: Upper forelimbs• Cat: Complete forelimbs• Human/Chimp: hands
Circling toward lesion, NO head tilt!Blindness: intact PLR, no menace
Localization for the BrainstemI. OlfactoryII. OpticIII. OculomotorIV. TrochlearV. TrigeminalVI. Abducens
VII. FacialVIII. VesibulocochlearIX. GlossopharingealX. VagusXI. Spinal AccessoryXII. Hypoglossal
Motor tracts (red nucleus, reticulospinal tracts) cross in midbrain.
Cranial Nerve Evaluation
Menace: II and VIIPLR: II and III (parasympathetic part)Strabismus
Static: III, IV, VIPositional: VIII
Nystagmus: VIII
Ear/lip/eye twitch: V and VIITemporal/masseter muscle: VGag: IX and XTrapezius muscle: XITongue movement: XII
Spinal Cord LocalizationDivided into cord segments based on the anatomic actionUpper motor neuron: cell body originating rostral to the foramen magnumLower motor neuron: cell body originating in the spinal cord
Spinal Cord SegmentsC1-C5: Upper Motor Neuron all 4 limbsC6-T2: Lower Motor Neuron front
limbs Upper Motor Neuron pelvic
limbsT3-L3: Upper Motor Neuron pelvic
limbsL4-S3: Lower Motor Neuron pelvic limbs
C1-C5 T3-L3 L4-S3C6-T2
Postural Reactions – Upper Motor Neuron Function
Hopping, placing, conscious proprioceptionNeed lower motor neurons intactBUT also uses white matter of spinal cord
Spinal Reflexes – Thoracic Limb Biceps brachii: musculocutaneousTriceps: radial nerveExtensor Carpi radialis: radial nerveWithdrawal: axillary median/ulnar musculocutaneous radial
Spinal Reflexes – Pelvic LimbPatellar: Femoral (L4-5)Sciatic: Sciatic (L6-S2)
Cranial tibial: peroneal (L6-7)Gastrocnemius: tibial (L7-S1)
Withdrawal: Sciatic (L6-S2)
Withdrawal is not conscious!!Withdrawal is not conscious!!