PowerPoint Presentation · Recurrent strabismus. These parents need LOTS of time ... cause a...
Transcript of PowerPoint Presentation · Recurrent strabismus. These parents need LOTS of time ... cause a...
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AVC 2017
Surgical treatment of childhood strabismus
LIONEL KOWAL MELBOURNE
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TODAY’S TALK
If / when / why surgery is a good next
step for your child
Esotropia ET
Exotropia XT
Complex strabismus
Cyclovertical problems CV
Developmentally Delayed Kids DDK
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Why surgery?
The child has symptoms or signs that
surgery can be expected to improve & after
a discussion about:
Benefits
Risks
Hassle / Costs
Alternative treatments
….I proceed, with the parents’ blessings
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Parents’ expectations have to = mine 1
Realignment fixes part - a large
necessary part, but only a part - of the
problem
Often, the only reliable outcome is
improved appearance
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Parents’ expectations have to = mine 2
ET: improved alignment: improved field
Perfect alignment necessary for 3D
Glasses may still be needed
Amblyopia Rx may still be needed and may
be more effective if the eyes are
straight[er]
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KEY TO SUCCESSFUL MNGMT OF PARENTS’
EXPECTATIONS: EDUCATION
‘HIGHLY RECOMMENDED [FREE!] E-BOOK FOR YOU TO READ’
Eye Muscle Problems in Children and Adults: A Guide to Understanding Burton J. Kushner, MD
The John W. and Helen Doolittle Professor of OphthalmologyUniversity of Wisconsin Department of Ophthalmology and Visual Sciences, Madison
…LINK ON MY WEBSITE
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Burton J. Kushner, MD
If knowledge is power, one of its powers is to enable us to make wise and informed decisions that influence our future.
Hopefully after reading this book you will feel more empowered to make considered choices regarding the treatment of your child, yourself, or your loved one.
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Overview of Surgery expectations
Two main groups
Low risk for 2nd surgery, good prognosis
for some sensorimotor fusion.
Higher risk [for 2nd surgery] & poorer
prognosis for some sensorimotor fusion.
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Low risk for 2nd surgery
Good prognosis for some sensorimotor fusion.
Acquired ET.
Stable measurements.
Pre-op sensory assessment suggests
postop fusion [PAT 1987 study].
Many cases of intermittent XT
Healthy child
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Higher risk for 2nd surgery
Poorer prognosis for some sensorimotor fusion
Infantile onset strab [IOS].
[Apparent] Cyclo Vertical Problems CVP
Delay till 1st straight.
Developmentally Delayed Kids DDK.
ASD/ADHD
Many cases of intermittent XT
Huge misalignments
Recurrent strabismus
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These parents need LOTS of time
Parents with expectations that will never be
met: expect / demand that one surgery will
give a perfect cure - perfect alignment,
appearance, 3D
Child has had unconventional ineffective
treatment for some years : need total
recalibration of parental ‘religion’.
Albinism: +ve angle Kappa common: when
aligned, look XT - beware
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Mentioning disaster outcomes:
Tailor to parent Most: Surgery is 99+% safe. Do you want more
detail?
Some parents:
Anesthetic disaster 1/100,000
Blind [usually infection] 1/10,000 – I have never seen it in Melbourne
Pedestrian/ passenger in a car: death rate 1/20,000 pa
New discussion: developmental problems after general anesthesia in young children - several references on my website
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DEVELOPING AN ESOTROPIA…
THE UNCORRECTED HYPEROPE or ‘Convergence Excess’ aka High AC/A
Prolonged inappropriate accommodation tendency to inappropriate convergence and increased tone in medial recti [vergence tonus]
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Developing an esotropia…2
Increased tone will lead to changes in Tension / Length ratio and eventually to structural changes inc changes in sarcomere density in MR that eventually exceeds motor fusional reserve and esotropia!
Then the MR starts to permanently shorten
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Esotropia
Core defect becomes a mechanically
abnormal MR.
Making the MR mechanically normal is a
necessary part of the fix
Accurate measurements, accurate
surgery: early alignment success in 90%
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BENEFITS OF REALIGNMENT OF ET
Normal appearance
Better peripheral field
Chance for sensory
fusion
Better chance to treat
resistant amblyopia
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TIMING OF ESOTROPIA SURGERY
Von Noorden
Ing
Europe
Wright
Costenbader
Parks
Tychsen & the Texans
…so many eminent contributors for decades –nearly all point to early or very early alignment as important
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Benefits : Appropriate surgery
makes for better neurology
J AAPOS 2005
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Surgery timing
ET: Infantile onset, Acquired
Improved % of good
alignment and sensorimotor
fusion if realigned within some
months in all cases of ET inc
IOS
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Exotropia
Infantile: common association with
developmental issues
Older: intermittent XT
Sensory XT
Indications for surgery less well defined
than for ET
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EXOTROPIA XT Core problem is usually subtle anomaly in
orbital anatomy, not a tight LR
A common 2° problem: hemiretinal suppression that ‘allows’ XT without
diplopia
Fixing the LR length & tension tries to compensate for the XT and improve the alignment & mechanics, but:
1. does not return the mechanics of this abnormal orbit to normal - this ‘allows’ some recurrence of XT
2. may not alter the suppression pattern even when straight - this ‘allows’ recurrent XT
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ESOTROPIA & EXOTROPIA
ET & XT
ET:
core problem is [or becomes] a tight medial rectus, driven by normal or Xs accom convergence
XT:
core problem is usually subtle anomaly in orbital anatomy [not a tight lateral rectus] &/or
‘soft’ neurological issues &/or
sensory adaptation to the XT
ET / XT ARE NOT MIRROR IMAGE CONDITIONS
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Exotropia
For this next child:
when and for how long do I use over-minus?
when should I refer for surgery?
EBM = Evidence Based Medicine
..or is it Eminence Based Medicine
LK: Refer if:
A cosmetic issue [ XT or MEC]
Spectacle intolerance
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BASICS OF TREATMENT : XT SURGERY
>50% early ET [5-10∆ desirable]
<10% persistent ET risk of amblyopia / troublesome diplopia depending on age
Some sense in deferring surgery till out of the amblyogenic age, hence minus lenses
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Exotropia: surgery results
2nd surgery
M1 2%
Y1 10%
Y10 30% [Baker]
Regain sensory fusion: many
Lose sensory fusion: some
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AVC 2017
Surgical treatment of childhood
strabismus
Real and pseudo- oblique dysfunctions are
common accompaniments of childhood
ET [& XT].
Add an extra layer/s of complexity to
cause, natural history, treatment planning
and expectations
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APPARENT ABNORMAL OBLIQUE
ANATOMY / FUNCTION
R IO OA
R SO UA
TIGHT RSR RIR ‘UA’
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CYCLO VERTICAL PROBLEMS
REAL AND PSEUDO – ALL LOOK THE
SAME
There are subtle ways to tell the
differences:
Fundus torsion
Commutative vs non-commutative
versions
Imaging
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SOME:
TRULY ABNORMAL OBLIQUE ANATOMY / FUNCTION
The 4 oblique muscles need to be built, grow
and work in perfect 3D symmetry.
At BEST they are very finely tuned with little
room for error, hence vertical fusional range
only ± 2-3 ∆.
Any imperfection will interfere with motor
fusion, and predispose to tropia – if hyperopic,
ET
Extreme example: Cong sup obl palsy
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ABNORMAL OBLIQUE ANATOMY / FUNCTION – NON PARETIC
WALTER FINK 1954! ANATOMY TEXTBOOKS OFTEN WRONG
20% of cadavers: > 30° difference b/w course of SO & IO
32
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SUBTLE ABNORMALITIES IN ORBITAL ANATOMY THAT CAUSE
ABNORMAL OBLIQUE FUNCTION
Unicoronal synostosis [ premature fusion of a coronal suture] : ~ slightly misshapen forehead.
Apparent IO OA ~50%Manifest strabismus in primary >50%
33
AA
PO
S
SN
EC
201
3
BAGOLINI 1982:
Isolated posteroplaced
trochlea is an
underrecognised cause of
idiopathic oblique
dysfunction
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EXTORTED ORBIT
Extorted right orbit and globe will
cause a V-pattern and apparent IO-OA
RIR
RSR
RMR
RLR
LMR
LIR
LSR
LLR
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ORBITAL PULLEY HETEROTOPY
RLR lower than RMR
R gaze: RLR will pull RE to R & down
LMR will adduct on the horizon: LE will then be higher than RE:Resembles LIOOA
Will be no fundus torsion: LIO surgery not expected to be effective
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RIGHT HYPERTROPIA
OVERELEVATION IN ADDUCTION
IDIOPATHIC RIGHT INFERIOR OBLIQUE OVERACTION?
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‘RIO OA’ DUE TO BIFID RLR
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A – XT : superiorly displaced LR’s
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Real and pseudo- oblique dysfunctions
….are common accompaniments of
childhood ET [& XT].
Add an extra layer of complexity to cause,
natural history, treatment planning and
expectations
Some definitely get better with time
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Preparation for the hospital experience
My website:
1. Ella’s Eye Surgery Experience
2. Amy’s adventure.
3. Gabriel's Eye Surgery Adventures
4. Briannah’s Book
5. Kara’s adventure
6. Noah’s adventure
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Hospital experience
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Special situations
Incomitant
Duanes Syndrome
Trisomy 21
Other developmentally delayed kids
DDK
Getting out of glasses
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Special situations
Incomitant:
Distance/ near
Left / right
Up / down
All need an explanation, an understanding,
and tailored surgery
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Special situations
Duane’s Syndrome
Complex++
Many false +ve & -ve diagnoses in Y1
Surgery still evolving: different
transpositions helpful in many pts
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Special situations
T21/ Downs
Expectations of surgery close to ‘normal’
kids
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Special situations
Other developmentally delayed kids DDK
Typically need 2-3 surgeries to achieve
good stable alignment
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Special situations
Getting out of glasses
ET with full +, & <+2.50 DSOU : realistic
to aim for uncorrected ET. Often
successful
Kids who still need full+ @ age 8 for
normal alignment & are +3 DSOU or less:
50+% will grow out of glasses in next 10y.
Measure BIFR for quantitative guidelines
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