Powerpoint on Muscles

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    The

    MuscularSystem

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    Smooth Muscle Cardiac Muscle Skeletal Musc

    Found in walls of holloworgans. Functions to move

    them.

    Pump heartAttach to skele

    Movement and po

    non striatedstriated(striped)

    striated

    Involuntary & rhythmic Involuntary & rhythmic Voluntary (except r

    Single nucleus Single nucleusCells are long with

    nuclei

    I. Types of muscle

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    Smooth Muscle

    Rhythmic contractions are calledPERISTALSIS.

    II. Anatomy of skeletal muscle and musclecontraction

    A. Fused cells form a sarcomere (theaction unit)

    B. Sarcomeres are made up ofACTIN and MYOSIN filamentproteins.

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    C. Myosin (thick) and actin (thin) overlap (castriations) and slide past each other to causcontraction.

    1. Muscle contraction occurs when a moto

    neuron (nerve cell) stimulates a skeletal mand causes the release ofNEUROTRANSMITTERS from sacs in thAXON TERMINAL. They diffuse across SYNAPTIC CLEFT and bind with receptorthe neighboring muscle cell - causing myoslide along actin.

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    CalciumTroponin

    Tropomyosin

    Actin

    Myosin

    III. Sliding filament theory

    A. Without calcium - Myosin cannoalong actin because binding sites acovered by chain. Troponin = lockTropomyosin = chain

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    Calcium binds to troponin causing itto unlock. Tropomyosin slides down

    Binding sites exposed. Myosinwalks along actin - muscle

    contracts

    E f

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    IV. Energy for contractionA. Cellular respiration

    makes ATP (and givesoff heat). Stage 1: Glycolysis (no O2needed) Stage 2: Citric acid cycle (O2

    needed) Stage 3: Electron transport chain(O2 needed)

    1. Blood supplies oxygen needed during citric acid cycle.

    2. MYOGLOBIN (found in muscles) stores oxygen.

    B When oxy en runs out durin strenuous activity lycolysis is used to m

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    B. When oxygen runs out during strenuous activity, glycolysis is used to m

    1.Less ATP is released

    C. Energy sources for contraction CREATINE PHOSPHATE can regenerafrom ADP (10 sec.).

    1. Toxic PYRUVATE molecules are converted into lactic acid.

    2. LACTIC ACID builds up in the muscles (before diffusing into bloo

    causes muscle soreness.

    V Muscular responses

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    V. Muscular responses

    A. THRESHOLD STIMULUS - The minimum stimulus required to causecontraction (called a twitch) .

    B. Each twitch has both a period of

    contraction and relaxation.1. The LATENT PERIOD describes thetime between two muscle twitches.

    2. The REFRACTORY PERIOD is theamount of time when a muscle fiber is

    unresponsive.