HOURLY TITRATED MISOPROSTAL vs DINOPROSTONE

for induction of labour

OBJECTIVEComparing the efficacy and safety of oral misoprostal vaginal dinoprostone gel

STUDY DESIGNRANDOMIZED CLINICAL TRIAL

• SUBJECTS: 160 women • INCLUSION CRITERIA: Singleton pregnancy of gestation 34 wks or longer with baseline bishop score <6• PRIMARY OUTCOME: Vaginal delivery within 24 hrs

RESULTS

Among the 160 women vaginal delivery was achieved in 100 women 44in dinoprostone group and 56 in misoprostal group

CONCLUSIONHourly titrated misoprostal can provide a safe and efficacious substitute for the expensive dinoprostone