Postgraduate Medical Journal · All enquiries should be addressed to the Medical Director,...
Transcript of Postgraduate Medical Journal · All enquiries should be addressed to the Medical Director,...
Postgraduate Medical Journal
EditorA. A. G. LEWIS B.Sc. M.D. F.R.C.P.
Advisory Editorial BoardA. G. Apley F.R.C.S.D. Barltrop B.SC. M.D. M.R.C.P. D.C.H.E. M. M. Besterman M.A. M.D. F.R.C.P.E. H. Brown D.M. M.R.C.P. D.C.H.A. E. R. Buckle F.R.C.S. F.R.C.O.G.H. L. Cochrane F.R.C.S.J. 0. Craig F.R.C.S.I. D.M.R.D. F.F.R.P. D. B. Davies M.A. M.D. M.R.C.P.H. Ellis M.A. D.M. F.R.C.S.J. D. Griffiths M.S. F.R.C.S.
J. P. Hopewell F.R.C.S.D. G. James M.A. M.D. F.R.C.P.S. B. Karani D.P.H. F.R.C.P.C. E. Newman C.B.E. M.D. F.R.C.P.K. I. Nissen F.R.C.S.J. W. Paulley M.D. F.R.C.P.T. A. J. Prankerd M.D. F.R.C.P.N. E. Stidolph F.R.C.S.P. K. Thomas B.SC. M.D. F.R.C.P.
Editorial Representative for U.S.A.D. Rabinowitz M.D. M.R.C.P. M.R.C.P.E.
Johns Hopkins University School of Medicine, Baltimore, Md
Editorial Representative for AustraliaSir Clive Fitts M.D.(MELB.) F.R.C.P. F.R.A.C.P.
Editorial AssistantMrs M. E. Coops B.SC.
Postgraduate Medical Journal is published monthlyfor the Fellowship of Postgraduate Medicine byBlackwell Scientific Publications Ltd. The annualsubscription is 120s ($20.00) post free, and the priceof single issues 15s ($2.50) postage extra. Ordersfor back issues published up to December 1966 andcorrespondence from Fellows and Associates shouldbe sent to The Secretary, The Fellowship ofPostgraduate Medicine, 9 Great James Street,London, W.C.1 (tel: CHAncery 6900); other ordersand business correspondence should be addressed toBlackwell Scientific Publications Ltd, 5 Alfred Street,Oxford (tel: Oxford 40201).
All editorial correspondence should be addressedto Dr A. A. G. Lewis, The Postgraduate MedicalJournal, 9 Great James Street, London, W.C.1(tel: CHAncery 6900).
Advertisement enquiries and bookings should beaddressed to S. & H. Fretwell Ltd, 267 PortlandRoad, London, S.E.25 (tel: 01-654 8921).
The Fellowship of Postgraduate Medicine wasfounded by a group of London consultants after theFirst World War to assist postgraduates, particularlythose coming to London from the Commonwealth,to pursue their studies. The Fellowship first publi-shed the Postgraduate Medical Journal to give infor-
mation about lectures, conferences and courses andto provide a monthly review of all branches ofmedicine.
Postgraduate Medical Journal publishes originalpapers on subjects of current clinical importanceand welcomes review articles with extensive, up-to-date bibliographies as guides to further reading.Several symposia are published every year, eachdevoted to a single subject and written, by invitation,by specialists in different disciplines. Every issueincludes authoritative Current Surveys of clinicalproblems, as well as well-documented Reports ofcases of particular interest, Book Reviews andPostgraduate News.A 'Notice to Contributors' is published on the
inside back cover of this issue. The Editor reservesthe right to make changes which may clarify orcondense papers where this is considered desirable.
(D The contents of this Journal are copyright and,subject to the provisions of Section 7 of the Copy-right Act, 1956, they may not be copied, adapted orreproduced without permission. Requests for per-mission to reproduce material elsewhere, either inwhole or in part, should be addressed to the Editor,Postgraduate Medical Journal, 9 Great James Street,London, W.C.1.
Postgrad. med. J. (December 1968) 44, 931-933.
Books receivedDiagnostic Methods. Edited by J. W. MILLS. Pp. 176. London:
Butterworths, 1968. 25s.Some Diseases of Animals Communicable to Man in Britain.
Edited by O. GRAHAM-JONES. Proceedings of a symposiumorganized by the British Veterinary Association and theBritish Small Animal Veterinary Association. Pp. xvi + 338,illustrated. Oxford: Pergamon Press, 1968. 126s.
Exfoliative Cytology of the Stomach. By D. D. GIBBS.Pp. x + 147, illustrated. London: Butterworths, 1968. 56s.
Common Medical Emergencies. A Guide for Junior Physicians.By R. H. SALTER. Pp. 148. Bristol: John Wright, 1968. 18s.
Carcinoma of the Breast. By F. D. MOORE, S. I. WOODROW,M. A. ALIAPOULIOS and R. E. WILSON. New EnglandJournal of Medicine. Medical Progress Series. London:J. & A. Churchill, 1968. $7.50. 62s. 6d.
Disorders of Sexual Potency in the Male. By J. JOHNSON.Pp. xi + 116. Oxford: Pergamon Press, 1968. 55s.
Mechanisms of Contraction of the Normal and Failing Heart'By E. BRAUNWALD, J. ROSS and E. H. SONNENBLICK'Pp. xi + 205, illustrated. New EnglandJournal of Medicine'Medical Progress Series. London: J. & A. Churchill,1968. $9.50. 80s.
Out-of-the-Body Experiences. By CELIA GREEN. Proceedingsof the Institute of Psychophysical Research, Volume II.Pp. 142. Oxford: Institute of Psychophysical Research,1968. 27s. 6d.
Biopsy Procedures in Clinical Medicine. Edited by A. E.READ. Pp. 193. Bristol: John Wright, 1968. 40s.
The Virology and Immunology of Cancer. By L. A. ZILBERand G. I. ABELEV. Translated from the Russian andedited by RUTH SCHACHTER. Pp. xii + 474, illustrated.Oxford: Pergamon Press, 1968. 165s.
Speaking and Writing in Medicine. The Art of Communication.By C. F. HAWKINS. Pp. xviii + 159. Springfield, Illinois:Charles C. Thomas, 1968. Price not given.
Intrathoracic Crises. By A. L. D'ABREU, A. B. TAYLOR andD. B. CLARKE. Pp. 335, illustrated. London: Butterworths,1968. 85s.
Non-Dispersive Infra-Red Gas Analysis in Science, Medicineand Industry. By D. W. HILL and T. POWELL. Pp. 222,illustrated. London: Adam Hilger, 1968. 104s.
Asylums. Essays on the Social Situation of Mental Patientsand Other Inmates. By ERVING GOFFMAN. Pp. 336. PenguinBooks, 1968. 8s.
Stigma. Notes on the Management of Spoiled Identity. ByERVING GOFFMAN. Pp. 174. Penguin Books, 1968. 5s.
Social Psychiatry in Practice. By MAXWELL JONES. PelicanOriginal. Pp. 190. Penguin Books, 1968. 5s.
New Editions
Charlesworth's Chiropodial Orthopaedics. By L. C. GIBBARD.Second Edition. Pp. 287, illustrated. London: Bailliere,Tindall and Cassell, 1968. 70s.
High Blood Pressure. By G. PICKERING. Second Edition.Pp. viii + 717, illustrated. London: J. & A. Churchill,1968. 120s.
Bacteriology and Immunology for Students of Medicine(formerly Bigger's Handbook of Bacteriology). By F. S.STEWART. Ninth Edition. Pp. viii + 603, illustrated.London: Bailliere, Tindall and Cassell, 1968. 55s.
Starling and Lovatt Evans Principles of Human Physiology.Edited by HUGH DAVSON and GRACE EGGLETON. Four-teenth Edition. Pp. xv + 1668, illustrated. London:J. & A. Churchill, 1968. 120s.
Histochemistry. Theoretical and Applied, Volume I. By A. G.EVERSON PEARSE. Third Edition. Pp. vii + 759, illustrated.London: J. & A. Churchill, 1968. 130s.
Drugs in Anaesthetic Practice. By F. G. WOOD-SMITH, H. C.STEWART and M. D. VICKERS. Third Edition. Pp. xi + 547.London: Butterworths, 1968. 84s.
Anaesthetics, Resuscitation and Intensive Care. A Textbookfor Students and Residents. By W. NORRIS and D. CAMPBELL.Second Edition. Pp. xi + 271, illustrated. Edinburgh andLondon: E. & S. Livingstone, 1968. 30s.
Book reviewsBlood Flow through Organs and Tissues
Edited by W. H. BAIN and A. M. HARPER. Proceedingsof an international conference, Glasgow, March 1967.Pp. xx + 515, illustrated. Edinburgh and London:E. & S. Livingstone, 1968. 84s.
This volume records the edited proceedings of an inter-national conference on blood flow through organs andtissues held in Glasgow in March 1967. There are a totalof fifty-eight papers representing eighty-nine participants andof particular interest are the full discussions which arereported, thanks to the generous use of the tape recorderduring the conference. The papers are grouped into sectionsdealing with techniques of measuring blood flow throughvessels and then with flow through specific organs-heart,lung, brain, muscle, skin, kidney and other viscera. Thepapers include contributions from the U.S.A., Canada,Denmark, Italy, Belgium and Germany as well as from theseislands and represent many disciplines among which arephysiology, engineering, surgery, cardiology and anaesthesia.The wide range of specialists drawn together in this conference
indicates the increasing interest in the subject of blood flowthroughout the various fields of medicine.The communications are highly technical and reflect the
considerable advances which moder techniques of radio-active clearance, dye dilution, strain gauges and electro-magnetic flow meters have made to the study of blood flowin various tissues in health and disease. Full bibliographies aregiven.
This volume will obviously prove to be a valuable referencework to the many workers in this important and rapidlyevolving field of applied physiology.Nutrition in Renal Disease
Edited by G. M. BERLYNE. Proceedings of a Conferenceheld at the University of Manchester on 29 and 30 June1967. Pp. 251 illustrated. Edinburgh and London:E. & S. Livingstone, 1968. 50s.
In his introduction to this report, Dr Berlyne makes thepoint that the papers and discussions, given by experts fromEurope and America, should be of interest not only to
Postgrad. med. J. (December 1968) 44, 934-936.
Postgraduate news
FELLOWSHIP OF POSTGRADUATE MEDICINEThe Fellowship usually holds the following courses
each year (approximate dates and times in parentheses):Medicine (M.R.C.P.)General Medicine. Connaught, London Chest, Whipps CrossHospitals (four weeks, twice yearly, April/May, October/November), St Stephen's Hospital (evenings, four weeks,twice yearly). Whittington Hospital (evenings, five weeks,twice yearly, May/June, October/November). Queen Mary'sHospital for the East End (weekend, twice yearly, June,December). Ashford Hospital, Middlesex (two Saturdays,twice yearly, May, November).Infectious Diseases. Hither Green Hospital (weekend, twiceyearly, March/November).Paediatrics (D.C.H.). Princess Louise Kensington Hospital(weekend, twice yearly, March, September/October).Surgery (F.R.C.S.)General Surgery. Connaught Hospital (weekend, twiceyearly, April, September/October). Queen Mary's Hospitalfor the East End (weekend, once yearly, February). RoyalMarsden Hospital (twice yearly, March, September).General Surgery and Orthopaedics. Fulham Hospital (threeweeks, evenings, twice yearly, March / April, September/October).Orthopaedics. Rowley Bristow Hospital, Pyrford (threealternate weekends, twice yearly, March/April, September/October).Please note that instruction arranged by the Fellowship ofPostgraduate Medicine is open only to Associates (annualsubscription, 21s.). Detailed syllabuses are published approxi-mately 6-8 weeks before courses begin and are circulated toall Associates. No entries to courses can be accepted inadvance of the syllabus being published.Information regarding courses can be obtainedfrom the officebetween 10 a.m. and 5 p.m., Mondavs to Fridays (Telephone242-6900), or by writing to the Secretary, Fellowship ofPostgraduate Medicine, 9 Great James Street, London, W. C. 1.
THE COMMONWEALTH AND INTERNATIONALMEDICAL ADVISORY BUREAUXThe Bureaux are maintained by the British Medical Associa-tion to provide a personal advisory service to doctorsvisiting the United Kingdom from all parts of the World.General information, as well as that on postgraduateeducation and accommodation is given.All enquiries should be addressed to the Medical Director,Commonwealth and International Medical Advisory Bureaux,British Medical Association, Tavistock Square, London, W. C. 1.
CAMBRIDGECambridge University Postgraduate Medical SchoolArrangements can be made for practitioners to attend thepractice of the United Cambridge Hospitals for short orlong periods. Advanced courses on special aspects of medicineand research are held from time to time.A revision course in Basic Medical Sciences will be held
on alternate Saturdays from October 1968 to March 1969and will consist of fifty lectures and demonstrations inpharmacology, physiology and physics, clinical measurement,and biochemistry; this course is intended primarily foranaesthetists preparing for the March 1969 primary
F.F.A.R.C.S., but others are welcome to attend. A courseon the Clinical Pathology of Organ Transplantation will beheld on 10 and 11 December 1968 at Addenbrooke'sHospital. Accommodation will be available in PembrokeCollege.
Refresher Courses for general practitioners will be heldat Norwich (5 days) 14-18 April 1969 and at Cambridge,30 June to 5 July 1969. A calendar of lectures, seminars andtutorials for the academical year 1968-69 and furtherinformation may be obtained from the Secretary, TheMedical School, Tennis Court Road, Cambridge.
Details of the teaching facilities available at the RegionalPostgraduate Medical Centres at the West Suffolk GeneralHospital, Bury St Edmunds, Fulbourn Hospital, the Norfolk& Norwich Hospital, The Ipswich and East Suffolk Hospital,the West Norfolk and King's Lynn Hospital, PapworthHospital and Peterborough District Hospital may beobtained from the Clinical Tutor at each of these Centres.
LIVERPOOLUniversity of Liverpool. Courses are held in Anaesthesia,Child Health, Medicine, Obstetrics and Gynaecology,Orthopaedic Surgery, Otorhinolaryngology, PsychologicalMedicine, Public Health, Radiodiagnosis and Radiotherapy,Surgery, Tropical Medicine and Hygiene and Venereology.After fulfilling the regulations, candidates may becomeeligible to take the Degrees of Ch.M., M.Ch.Orth. andM.Ch.Otol., and the Liverpool Diplomas, D.P.H., D.P.M.,D.T.M.&H., D.M.R.(D) or D.M.R.(T).The other courses are designed for students working for theLondon Diplomas.There is also a day-release course in the Basic MedicalSciences for junior hospital staff.Further information may be obtained from the Heads of theappropriate departments of the University, Liverpool 3.
OXFORDUniversity of Oxford
Enquiries about research training and advanced studiesmay be addressed to the head of the relevant clinical orlaboratory departments in the teaching hospitals or to theDirector of Postgraduate Medical Studies (address below).Neuroanatomy and physiology. A one week course suitablefor D.P.M. and M.R.C.P. candidates, with lectures, discus-sions, demonstrations, and dissection, is held in the Univer-sity Department of Human Anatomy annually in September,Fee: £10.Psychiatry. Three-day courses covering selected topics,suitable for D.P.M. Part II candidates are held three to fourtimes a year.Surgery. Subject to there being sufficient demand, a two-weekcourse suitable for final F.R.C.S. candidates will be heldtwice a year in September and April. Fee: £15.General Practice. Clinical attachments (including residentobstetric attachments) and individual programmes of atten-dance in the hospital departments, recognised under Section48 N.H.S. Act. Occasional short courses at Oxford andDistrict Medical Centres in the region.
Enquiries about any of the above, and about study daysand courses in special subjects arranged for those in theOxford region working for higher qualifications, to theDirector, Postgraduate Medical Studies, Medical School, 43Woodstock Road, Oxford.
Postgraduate news
GLASGOWSurgery. An intensive course of instruction in the basicsciences suitable for candidates preparing for the PrimaryFellowship Examination in Surgery is held from October toDecember. A modified form of the course is available forcandidates preparing for the D.A. or F.F.A. examinations,Fee £30.Anaesthetics. A course for specialist anaesthetists and forthose preparing for the final part of the F.F.A.R.C.S. willbe held in May. Fee £10 10s.Medicine. An intensive course on Recent Advances inClinical Medicine suitable for candidates preparing for theMembership Examination is held twice annually for afortnight in March and September. Fee £15 15s.Geriatrics. A course for trainee specialists in GeriatricMedicine or General Practitioners in charge of geriatric bedsin hospitals is held in May. Fee £7 10s.Child Health. A formal course held in May and Novemberfor those preparing for the D.C.H. and M.R.C.P. with ChildHealth as a special subject. Fee £15 15s.Obstetrics. An intensive week's course of instruction inobstetrics for those preparing for the D.Obst.R.C.O.G. heldin September. Fee £7 10s.Mental Deficiency. An intensive course in Mental Deficiencyis held for 3 weeks in October. The course includes lecturesand demonstrations in mental handicap and deficiency,instruction in mental testing and visits to institutions.Fee £18.Introduction to Psychiatry. An intensive course providing ageneral introduction to psychiatry is held for 3 weeks inNovember. The course includes theoretical and clinicalinstruction in child psychiatry and psychology and adultpsychiatry. It is particularly suitable for medical officersconcerned with public health. Fee £18.Steroid Endocrinology. A course for clinicians and hospitallaboratory workers with special interest in Endocrinologyand for those in general medicine who wish to have a betterunderstanding of treatment with steroid hormones is held inApril. Fee £15.Diagnostic Virology. A course for experienced laboratoryworkers who wish to develop diagnostic virology for epidemi-ological purposes in this country and abroad is held in April.Fee £25.Histopathology of the Skin. A course for pathologists andthose with some training in pathology is held for 1 week inMarch. Fee £7 10s.Forensic Medicine. A postgraduate course in the UniversityDepartment of Forensic Medicine is held for 10 weeks fromApril to June. Fee £15.Clinical Attachments. A scheme for clinical attachments ingeneral medicine, general surgery and various specialties hasbeen arranged to assist those working for higher qualifica-tions. An attachment may be started at any time. No formalinstruction is given, but participants can gain intensive clinicalexperience by following the day-to-day work of a unit in aGlasgow teaching hospital. Fee £5 per month. Registrationfee£1lIs.Teaching Ward Rounds. Each academic term a course of tenteaching ward rounds in Medicine is arranged. These occupyone afternoon a week. Fee £8 8s.Radiology. A course in radiological interpretation forclinicians. Lecture demonstrations on alternate Tuesdays inconjunction with Teaching Ward Rounds. Fee £5 5s.Dermatology. An intensive week's course in dermatology.Suitable for M.R.C.P. candidates. March. Fee £7 1Os.A week-end course in dermatology. May. Fee £3 3s.
Research Techniques in Experimental Surgery and Anaesthesia.A 2-day course giving an introduction to research techniquesin Experimental Surgery and Anaesthesia. March. Fee £3 3s.Steroid Endocrinology. A course for clinicians and hospitallaboratory workers with a special interest in Endocrinologyor for those in General Medicine who wish to have a betterunderstanding of treatment with steroid hormones. April.Fee £15.Medical Ophthalmology. An intensive weekend course onthe ophthalmological aspects of general medicine. Suitablefor M.R.C.P. candidates. May and October. Fee £5 5s.
GENERAL PRACTITIONER COURSES
Two Refresher Courses for general practitioners are heldannually - for a fortnight in May and September. Two-weekpostgraduate residencies are available continuously inmaternity hospitals in the Western Region.Clinical Attachments - continuous. Full-time or part-timeattachments to hospital teaching units to enable GeneralPractitioners to increase their experience and keep up to datewith recent trends and advances. Fee £1 5s. per week forfull-time attachment.
Extended Courses and 1-day course covering selected topicsin general subjects or the specialties held in teaching hospitalsin Glasgow and principal hospitals in other parts of theWestern Region. Meetings are generally held on Sundaysfrom October to May and are arranged by the West ofScotland Faculty of the College of General Practitionersfrom whom full details are available.
Full-time Course. The Board offers full-time postgraduatecourses in Radiology (2 years) and Radiotherapy (2 years).The University offers full-time postgraduate courses leadingto the following diplomas:Diploma in Public Health (1 year)Diploma in Clinical Psychology (2 years).
Conference. Specialist conferences on various topics areheld twice a year in the Hall ofthe Royal College of Physiciansand Surgeons. In these, invited guests and local speakersdiscuss current topics and time is provided for audienceparticipation. These conferences are designed particularlyfor consultants and registrars.
Further information and application forms can be obtainedfrom the Director of Postgraduate Medical Education, TheUniversity, Glasgow, W.2.
NEWCASTLE UPON TYNE
Courses of three to four sessions in various Medical andSurgical subjects on a weekly sessional basis during term-time.Suitable for those preparing for a higher qualification.Clinical attachments, full-time or part-time, throughout theyear.Attachments of 1 or 2 weeks for general practitioners inGeneral Medicine, Dermatology, Obstetrics, Paediatrics,Psychiatry, Geriatrics and other subjects by arrangement.Recognized under Section 48 of the N.H.S. Act.Further detailsfrom the Postgraduate Sub-Dean, Organizationfor Postgraduate Medical Education, The Medical School,The University, Newcastle upon Tyne.University courses for postgraduate diplomas. D.P.M. andD.P.H. Further details from the Assistant Registrar, MedicalSchool, The University, Newcastle upon Tyne.
935
Postgraduate news
THE ROYAL COLLEGEOF GENERAL PRACTITIONERSMedical Recording ServiceKitts Croft, Writtle, Chelmsford, Essex. (Tel. Writtle 316).Selection of titles available on tape (5 in reels running at31 ips). These talks may be borrowed by any doctor any-where in the world.
Tape course in geriatricsThis series of seven tapes on aspects of the medical care of theelderly is given by Dr M. K. Thompson, a General Practi-tioner, who has made a special study of geriatrics.The tapes are primarily intended for the trainee General
Practitioner, but should also be listened to by all GeneralPractitioners, Health Visitors, District Nurses and those whohave to deal with the elderly. Each tape is complete in itselfandthe series can be listened to in any order as desired. The costof borrowing the series will be £2 15s. including postage atthe Second Class Mail rate.
68-43 Cerebral Syndromes in the Elderly. 39 min, 21 slides.68-40 The Mind in Old Age. 33 min.68-59 Sight and Hearing in Old Age. 24 min.
68-10 Examining the Elderly. 25 min, 21 slides.68-41 Incontinence of Urine in Old Age. 34 min.68-58 Hazards of Old Age. 30 min, 21 slides.68-60 Heart Disease and the End of Life. 22 min.
WEST MIDDLESEX HOSPITAL. POSTGRADUATEMEDICAL LECTURES.5 December Radioiodine in the Diagnosis and Treatment
of Thyrotoxicosis and Thyroid Cancer-Dr. E. E. Pochin
Thursday at 5 p.m. in Lecture Theatre, West MiddlesexHospital, Isleworth, Middlesex. Tea and biscuits at 4.45 p.m.
ST CHARLES'S HOSPITAL. SURGICAL EVENINGSInformal Surgical Evenings will be held in the MedicalCentre, St Charles's Hospital, Ladbroke Grove, London W.10on the second and fourth Thursdays of each month, 7.30 p.m.to 9 p.m.
12 December Clinical Evening. Discussion of SurgicalPatients.
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POSTGRADUATE( 2
c
MEDICAL JOURNAL
VOLUME 44January to December 1968
BROWN UNIVERSITYLIBRARYMAY 51969
PUBLISHED FOR
THE FELLOWSHIP OF POSTGRADUATE MEDICINE
BY BLACKWELL SCIENTIFIC PUBLICATIONS
OXFORD AND EDINBURGH
Published byBlackwell Scientific Publications
5 Alfred Street, Oxfordfor The Fellowship ofPostgraduate Medicine9 Great James StreetLondon, W.C.1.
Printed in Great Britain byBurgess & Son (Abingdon) Limited
Abingdon-on-Thames
Subject IndexPage
Abdomen and thorax-stab-wounds and otherpenetrating injuries of the. . . J. B. Garland 127
Abdominal aortic aneurysm . . . renal arterystenosis due to . . . M. N. Lowenthal, S. A.Doctor and J. Fine 928
Abnormalities-vascular-, blood sugars-and sur-vival-the Oxford study after 17 years. J. B.O'Sullivan, J. Cosgrove and D. McCaughan 955
Absorption and metabolism of vitamin D aftergastric surgery . .. Studies in the . . . Gilbert R.Thompson 626
The Achilles tendon reflex as an index to thyroidfunction. George Nuke and R. I. S. Bayliss 97
A case of acute hyperparathyroidism, with thyro-toxicosis and pancreatitis, presenting ashyperemesis gravidarum. M. A. 0. Soyannwo,M. G. McGeown, T. G. Milliken 861
A case of oat-cell carcinoma of the lung with thecarcinoid syndrome. M. Govindaraj 815
Acidosis ... plasma 'ketone' level in the diagnosisand treatment of diabetic .. . M. S. Knapp andMargaret F. Horn 799
Addison's disease and pernicious anaemia-diabetes mellitus . . . R. C. Turner and ArnoldBloom 555
A death from tetracycline. Gillian C. Hanson 870Adenoma-oliguric glomerulonephritis and para-
throid ... Jacqueline A. Woolcock and Allen B.Shaw 246
Adenomata with special reference to the Zollinger-Ellison syndrome ... peptide-secreting . .. W.Sircus 742
Adrenal diagnosis-some recent advances inC. L. Cope and D. Mattingly 23
Adrenal relations-thyroid and . . . Victor Parsonsand Ian Ramsay 377
Adult coeliac disease. J. S. Stewart 632Adult nephrotic syndrome in Ibadan, Nigeria: a
prospective study of 135 cases. 0. 0. Akinkugbeand Mollie Hunton 903
Age, glucose tolerance and atherosclerosis. K. J.Kingsbury 944
A medical emergency treated by anti-mitotic drugs.W. S. B. Lowry 926
Amputation for peripheral vascular disease . . . gasgangrene after . I. G. Schraibman. 551
Anaemia, by iron-dextran infusion, with specialreference to the effect on blood-grouping, coagu-lation, sedimentation and haemolysis. The treat-ment of iron-deficiency ... Bernard M. Groden,James Whitelaw and George Will 433
Anaemia complicating methyldopa therapy-auto-immune haemolytic . . . Ivor Surveyor, ByronEvans, K. C. Saunders and T. E. Parry 438
Anaemia-diabetes mellitus, Addison's disease andpernicious ... R. C. Turner and Arnold Bloom 555
Anaemia-with reticulo-endothelial siderosis in acase of hypernephroma. Sideropenic . . . D.Chatterjee and G. E. Maclellan 259
Analgesic nephropathy and papillary necrosis ...
Priscilla Kincaid-Smith 807
PageAn association between Wernicke's encephalopathyand thyrotoxicosis. B. A. Enoch and D. M.Williams 923
Anastomosis-recovery of villous architecture ingluten enteropathy exacerbated by gastro-jejunal ... D. G. Weir 234
Aneurysm-renal artery stenosis due to abdominalaortic ... M. N. Lowenthal, S. A. Doctor andJ. Fine 928
Angiotensin-studies on the metabolism of . . .
Austin E. Doyle 31Anhidrotic ectodermal dysplasia presenting as a py-
rexia of undetermined origin in the neonatalperiod ... J. Mills 193
Ankle fractures-a plea for simplicity in the classi-fication of ... R. S. Phillips, C. J. E. Monk andG. A. Balmer 199
Anorexia nervosa-serum cholesterol levels in ...L. M. Blendis and A. H. Crisp 327
Antagonism-synalbumin insulin ... J. Vallance-Owen 117
Aneurysm after myocardial infarction . . . car-diac ... Bernard M. Groden, W. B. James andIan McDicken 775
Anti-mitotic drugs . . . A medical emergencytreated by ... W. S. B. Lowry 926
Aortic aneurysm . . . renal artery stenosis due toabdominal. . . M. N. Lowenthal, S. A. Doctorand J. Fine 928
A plea for simplicity in the classification of anklefractures. R. S. Phillips, C. J. E. Monk andG. A. Balmer 199
Arterial disease-the effect oftreatment ofmoderatehyperglycaemia on the incidence of ... H. Keen,T. J. Jarrett, C. Chlouverakis and D. R. Boyns 960
Arteriography of the coeliac axis and superiormesenteric artery in five cases of haemochroma-tosis with particular regard to the pancreaticcirculation. L. A. Scuro, G. Curri, G. Monti, R.Zuin and S. Romani 460
Arteriography ... pancreatic and mesenteric ...E. Herlinger 755
Arteriopathy . .. intrahepatic granulomatous ...H. Fox, M. G. Gleeson and W. F. W. E. Logan 256
Arterio-venous fistula with associated carcinomaof the kidney . . . Intra-renal . . . W. J. Mac-Lennan and R. Scott 867
Artery stenosis due to abdominal aortic aneurysm... renal ... M. N. Lowenthal, S. A. Doctor andJ. Fine 928
Arthritis and ulcerative colitis-purpura hyper-globulinaemia in association with rheumatoid ...E. N. Wardle 433
Arthritis ... hard and soft osteo- . . . C. P. Broad 848A simplification of the knee-joint menisectomy
operation. S. Schwartz 212Aspergillosis complicating healed tuberculosis-pneumonic ... E. Freeman 181
Aspergillosis-in two families ... pulmonary ...R. H. Ellis 178
Postgraduate Medical Journal
A study ofpre-operative sedatives. James Parkhouseand Joan Mahoney 229
Atherosclerosis, diabetes and hypertension. W. B.Robertson 939
Atherosclerosis, glucose tolerance and age. K. J.Kingsbury 944
Atrial flutter with complete heart block in a case ofstaphylococcal septicaemia ... Effect of direct-current countershock on . . . James Buchananand Ronald J. Weir 811
Attitude: applications to clinical research-measurements of personality and ... Isaac Marks 277
Autoimmune disease of the gastro-intestinal tract.Ralph Wright 765
Autoimmune haemolytic anaemia complicatingmethyldopa therapy. Ivor Surveyor, ByronEvans, K. C. Saunders and T. E. Parry 438
Behcet's syndrome... major vascular complicationsin ... B. Anthony Enoch, J. L. Castillo-Olivares,T.C.L. Khoo, R.G. Grainger and L. Henry 453
Benign duodenocolic fistula ... Unusual method ofdiagnosis in a new case of ... J. H. P. Cuddiganand M. A. Edgar 481
Biguanides in diabetes mellitus ... the uses of ...H. Keen, and R. J. Jarrett 466
Bilateral retrobulbar neuritis due to insecticides.H. R. Jindal 341
Biochemistry of hyperthyroidism and hypo-thyroidism. Frederic L. Hoch 347
Biopsy needle ... repeated samples of fat obtainedwith a . . . C. G. Hunter and R. R. Kendrick 851
Blindness after cardiac arrest. A. H. Sabah ... 513Blood flow-forearm-and heart rate after haemor-
rhage. 0. G. Edholm and J. D. Hatcher 35Blood-grouping, coagulation, sedimentation and
haemolysis ... the treatment of iron deficiencyanaemia by iron-dextran infusion, with specialreference to the effect on . . . Bernard M. Groden,James Whitelaw and George Will 433
Blood sugars, vascular abnormalities and survival-the Oxford study after 17 years. J. B. O'Sullivan,J. Cosgrove and D. McCaughan 955
Bone disease ... gastric resection and metabolic ...C. N. Pulvertaft 618
Bone sclerosis in infancy. Joan M. R. MacCarthy 908Breast cancer ... Present treatment of ... J. L.Grogono 501
Bronchial muscle ... studies on the action of ...John Crofton 26
Bronchitis and emphysema . . . research into ...
C. M. Fletcher, N. L. Jones and E. J. M.Campbell 48
Bronchogenic carcinoma . . . Effects of differentregimes of metyrapone on steroid production byapatient with a corticotrophin-secreting ... JudithM. Steel and A. A. H. Lawson 485
A 'burnt-out' case of sarcoidosis. J. G. Scadding 105
Cancer ... present treatment of breast . . . J. L.Grogono 501
Carbenicillin in the treatment of septicaemia andmeningitis . . . experiences with . . . A. E.Richardson, C. R. Spittle, K. W. James and0. P. W. Robinson 844
Carbon monoxide poisoning-muscle necrosis andacute renal failure in ... A. L. Linton, J. HumeAdams, and D. H. Lawson 338
Carbon tetrachloride poisoning-infectious mono-nucleosis like syndrome following haemodialysisfor ... A. T. Proudfoot and R. H. MacDonald 249
Carcinoid syndrome ... a case of oat-cell carcinomaof the lung with the ... M. Govindaraj 815
Carcinoma and its treatment-thyroid . . . SelwynTaylor 404
Carcinoma ... effects of different regimes ofmetyra-pone on steroid production by a patient with acorticotrophin-secreting bronchogenic ... JudithM. Steel and A. A. H. Lawson 485
Carcinoma of pancreas . . . Cushing's syndromeassociated with . .. Alaf Khan 925
Carcinoma of the kidney . . . intra-renal arterio-venous fistula with associated . . . W. J. Mac-Lennan and R. Scott 867
Carcinoma of the lung with the carcinoid syndrome... a case of oat-cell . . . M. Govindaraj 815
Carcinoma with multiple ectopic hormone secretionand associated myopathy. Derek R. Cullen andBernard E. Tomlinson 472
Cardiac aneurysm after myocardial infarction.Bernard M. Groden, W. B. James and IanMcDicken 775
Cardiac arrest ... blindness after ... A. H. Sabah 513Calcitonin ... a review of experimental and clinical
investigations. G. V. Foster 411Cardiomyopathy ... mitral regurgitation in con-
gestive ... J. F. Goodwin 62Cardiomyopathy. The systolic murmur in hyper-
trophic obstructive . . . and the nature of theobstruction ... N. Nellen and M. S. Gotsman 89
Cardiovascular action of suprarenal extract . . .
Oliver and Schafer's discovery of ... H. Barcroftand J. F. Talbot 6
Carotid endarterectomy in cerebral vascular disease.W. Rex Morris 242
Central nervous system ... chemical mediators inthe ... P. K. Lahiri and P. Sen 167
Cell culture . . . some studies on inherited diseaseusing the techniques of ... A. G. Beam 9
Cerebral vascular disease ... carotid endarterec-tomy in ... W. Rex Morris 242
Chemical mediators in the central nervous system.P. K. Lahiri and P. Sen 167
Cheshire cat syndrome ... E. G. L. Bywaters 19Childhood ... constipation in ... W. Henderson 724Cholesterol levels in anorexia nervosa ... serum ...
L. M. Blendis and A. H. Crisp. 327Cholesterol metabolism . . . the regulation of ...N. B. Myant 86
Chronic pancreatitis: medical aspects ... Henry T.Howat 733
Circulation-arteriography of the coeliac axis andmesenteric artery in five cases of haemochroma-tosis with particular regard to the pancreatic. . .L. A. Scuro, G. Curri, G. Monti, R. Zuin andS. Romani 460
Cirrhosis-hepato-lienal fibrosis without ... non-cirrhotic intrahepatic portal hypertension . . .
Sheila Sherlock 109
iv
Index to Volume 44
Clinical investigations. Calcitonin. A review ofexperimental and ... G. V. Foster 411
Clinico-pathological aspects of the neurosyphiliticpsychoses. Kenneth Dewhurst 903
Clubbing associated with myxoedema . . . LATSactivity, exophthalmos and digital . . . PeterBeighton 246
Coagulation, sedimentation and haemolysis. Thetreatment of iron-deficiency anaemia by iron-dextran infusion, with special reference to theeffect on blood grouping ... Berhard Groden,James Whitelaw and George Will 433
Coeliac axis and superior mesenteric artery in fivecases of haemochromatosis with particular regardto the pancreatic circulation. L. A. Scuro,G. Curri, G. Monti, R. Zuin and S. Romani 460
Collaterals, the formation of ... C. T. Dollery 28Congenital shortening of one femur in one identical
twin. C. E. A. Holden 813Contrast radiography of the nasopharynx. GordonEvison 825
Corticotrophin-secreting bronchogenic carci-noma ... effects of different regimes ofmetyraponeon steroid production by a patient with a ...
Judith M. Steel and A. A. H. Lawson 485Classification of ankle fractures-a plea for sim-
plicity in the ... R. S. Phillips, C. J. E. Monk andG. A. Balmer 199
Clinical assessment of lymph-nodes after endolym-phatic radio-iodine . . Difficulty in ... J. Blake 336
Clinical patterns and complications of diabetesmellitus in India. H. B. Lal, A. L. Bahl, R. N.Chugh, K. P. Mathur and A. S. Bhalla 223
Clinical research .. measurements of personalityand attitude ... Isaac Marks 277
Coeliac disease . . . adult ... J. S. Stewart 632Colitis ... Ischaemic . . . B. C. Morson 665Colitis ... The medical treatment of ulcerative ...
Geoffrey Watkinson 696Colitis ... the surgical treatment of ulcerative ...
J. C. Goligher 708Colitis . . . the systemic complications of ulcera-
tive ... G. Watkinson 693Colon ... diverticular disease of the ... T. G. Parks 680Colon syndrome . . . the irritable ... A. M. Connell 668Coma . . . hyperosmolar non-keto-acidotic dia-
betic ... Anthony Martin 218Comments on the incidence and natural history of
gastric and duodenal ulcer. C. N. Pulvertaft 597Complications of diabetes mellitus in India . . .
clinical patterns and . . H. B. Lal, A. L. Bahl,R. N. Chugh, K. P. Mathur and A. S. Bhalla 223
Congenital malformations. A clinico-pathologicalconference held at the Royal Alexandra Hospitalfor Sick Children. Trevor P. Mann 148
Congestive cardiomyopathy ... mitral regurgitationin . . . J. F. Goodwin 62
Constipation: definition and classification. J. M.Hinton and J. E. Lennard-Jones 720
Constipation in childhood. W. Henderson 724Constipation in the elderly. E. Gordon Wilkins 728Coronary crisis . . the management of the ...
J. P. Shillingford 111Coronary disease and diabetes. D. A. Pyke 966
Crohn's Disease: natural history and treatment.J. E. Lennard-Jones
Cushing's syndrome associated with carcinoma ofpancreas. Alaf Khan
Cystic disease of the kidney. Its occurrence in twosiblings ... Medullary ... Satya Paul Handa andRobert Tennant
674
925
792
Deficiency in man ... disaccharidase ... A. M.Dawson 646
Diabetes, hypertension and atherosclerosis. W. B.Robertson 939
Diabetes-coronary disease and ... D. A. Pyke 966Diabetes mellitus, Addison's disease and pernicious
anaemia. R. C. Turner and Arnold Bloom 555Diabetes mellitus ... the uses of biguanides in ...H. Keen and R. J. Jarrett 466
Diabetes-serum-insulin response to glucose inpancreatic ... S. Bank, W. P. U. Jackson, P.Keller and I. N. Marks 212
Diabetic acidosis . .. plasma ketone level in thediagnosis and treatment of ... M. S. Knapp andMargaret E. Horn 799
Diabetic coma ... hyperosmolar non-keto-acido-tic ... Anthony Martin 218
Diagnosis in a new case of benign duodenocolicfistula ... unusual method of... J. H. P. Cuddi-gan and M. A. Edgar 481
Diagnosis . . . spatial vectorcardiogram inD. Emslie-Smith and K. G. Lowe 39
Diffusing capacity in obstructive lung disease ...distribution of ... William A. Briscoe 16
Difficulty in clinical assessment oflymph-nodes afterendolymphatic radio-iodine. J. Blake 336
Digital clubbing associated with myxoedema-LATS activity, exophthalmos and . . PeterBeighton 246
Digital osteosclerosis ... primary Raynaud's diseaseassociated with sclerodactyly and . D. N.Golding and H. Baker 553
Direct-current countershock on atrial flutter withcomplete heart block in a case of staphylococcalsepticaemia ... effect of... James Buchanan andJ. Weir 811
Disaccharidase deficiency in man. A. M. Dawson 646Disc ... a pre- and post-operative study of forty-
six cases of slipped intervertebral ... G. Harto-Garofalidis, Ch. Rigopoulos, N. Papavassiliousand B. T. Papathanassiou 144
Diverticular disease of the colon. T. G. Parks 680Drugs ... a medical emergency treated by anti-
mitotic ... W. S. B. Lowry 926Drug ... Phenformin as a fibrinolytic ... G. R.Feamley 468
Drugs ... psychotropic. John Hinton 286Duodenal obstruction due to an anomalous portal
vein. V. V. Kakkar and A. M. B. Tompkin 189Duodenal ulcer ... comments on the incidence and
natural history of the gastric and . . C. N.Pulvertaft 597
Duodenal ulcer ... the medical treatment of gastricand ... M. J. S. Langman 603
Duodenocolic fistula . . unusual method ofdiagnosis in a new case of benign ... J. H. P.
v
vi Postgraduate Medical Journal
Cuddigan and M. A. Edgar 481Dysplasia presenting as a pyrexia of undetermined
origin in the neonatal period . . . Anhidroticectodermal... J. Mills 193
Ectodermal dysplasia presenting as a pyrexia of un-determined origin in the neonatal period . . .
Anhidrotic... J. Mills 193Ectopic gestation in a tubal stump. S. Krzaniak 191Effect of direct-current countershock on atrial
flutter with complete heart block in a case ofstaphylococcal septicaemia. James Buchananand Ronald J. Weir 811
Effect of different regimes of metyrapone on steroidproduction by a patient with a corticotrophinbronchogenic carcinoma. Judith M. Steel andA. A. H. Lawson 854
Embolism . . . the surgical treatment of acutemassive pulmonary ... H. P. Gautam 971
Emphysema... research into bronchitis and ... C.M. Fletcher, N. L. Jones and E. J. M. Campbell 48
Encephalopathy and thyrotoxicosis ... an associa-tion between Wernicke's. B. A. Enoch andD. M. Williams 923
Encephalopathy . . . penicillin .. . N. Conway,E. Beck and Jane Somerville 891
Encephalopathy ... the pathogenesis and medicaltreatment of hepatic ... A. E. Read 652
Endarterectomy in cerebral vascular disease . . .
carotid... W. Rex Morris 242Endocarditis parietalis fibroplastica (Loffler's
disease). R. C. Jennings and C. D. R. Pengelly 251Endolymphatic radio-iodine ... difficulty in clinical
assessment of lymph-nodes after ... J. Blake 336Enterocyte . . . Enteropoiesis: structural and func-
tional relationships of the ... C. C. Booth 12Enteropoiesis: structural and functional relation-
ships of the enterocyte. C. C. Booth 12Enzyme defects . . . hypothyroidism due to ...
E. M. McGirr and John A. Thomson 398Epidemiological psychiatry . . . recent progress
in ... Brian Cooper 331Epilepsy ... psychiatric aspects of... Donald F.
Scott 319Epping jaundice after two years. Harry Kopelman 78Erythrocyte sedimentation rate in acute gastro-
duodenal haemorrhage. Pyrexia and elevated ...R. S. Chapman and S. D. Mohamed 238
Excretion ... a modified index of phosphate ...B. E. C. Nordin and L. Bulusu 93
Exophthalmos and digital clubbing associated withmyxoedema... LATS activity... Peter Beighton 246
Experiences with carbenicillin in the treatment ofsepticaemia and meningitis. A. E. Richardson,C. R. Spittle, K. W. James and 0. P. W.Robinron 844
Experimental and clinical investigations ... Calci-tonin ... a review of... G. V. Foster 411
Fasting, total, in the treatment of obesity. I. C.Gilliland 58
Fat obtained with a biopsy needle . . . repeatedsamples of... C. G. Hunter and R. R. Kendrick 851
Femur in one identical twin, congenital shorteningof one ... C. E. A. Holden 813
Fibrinolytic drug ... phenformin as a ... G. R.Fearley 468
Fibrosis . . . hepato-lineal . . . without cirrhosis:non-cirrhotic intrahepatic portal hypertension.Sheila Sherlock 109
Fistula ... unusual method of diagnosis in a newcase ofbenign duodenocolic... J. H. P. Cuddiganand M. A. Edgar 481
Fistula with associated carcinoma of the kidney ...
intra-renal arteriovenous... W. J. MacLennanand R. Scott 867
Folic acid ... failure of... to influence mortality ofrats with acute tubular necrosis caused by mer-cury ... I. Taraba and G. M. Bull 116
Forearm blood flow and heart rate after haemor-rhage ... 0. G. Edholm and J. D. Hatcher 35
Foreign bodies and their complications . . . themanagement of oesophageal. R. J. Donnelly andP. B. Deverall 830
Fractured fifth metacarpal ... non-union of a ...
C. P. Broad 819Fractures-a plea for simplicity in the classification
of ankle ... R. S. Phillips, C. J. E. Monk andG. A. Balmer 199
Gallstone pancreatitis ... the pathogenesis of...J. E. Trapnell 497
Gangrene after amputation for peripheral vasculardisease... gas... I. G. Schraibman 551
Gas gangrene after amputation for peripheral vascu-lar disease ... I. G. Schraibman 551
Gastric and duodenal ulcer ... comments on theincidence and natural history of . . . C. N.Pulvertaft 597
Gastric and duodenal ulcer... the medical treat-ment of... M. J. S. Langman 603
Gastric resection and metabolic bone diseaseC. N. Pulvertaft 618
Gastric surgery . . . studies in the absorption andmetabolism of vitamin D after . . . Gilbert R.Thompson 626
Gastric surgery . . . the late results of . . . C. N.Pulvertaft 613
Gastric teratoma. S. R. Meadow 183The gastrocamera. G. D. Hadley 763Gastro-duodenal haemorrhage-pyrexia and eleva-
ted erythrocyte sedimentation rate in acute . . .
R. S. Chapman and S. D. Mohamed 238Gastroenterological problems . . . the application
of motility problems to ... J. J. Misiewicz 749Gastro-intestinal disease. Protein malnutrition in...G. Neale 642
Gastro-intestinal haemorrhage... medical aspectsof... G. N. Chandler 586
Gastro-intestinal haemorrhage... surgical aspectsof... C. G. Clark 590
Gastro-intestinal tract ... autoimmune disease ofthe ... Ralph Wright 765
Gastro-jejunal anastomosis ... recovery of villousarchitecture in gluten enteropathy exacerbatedby... D. G. Weir 234
Geriatrics ... Psychological aspects of... Felix Post 307Gestation in a tubal stump . . . ectopic ... S.
Krzaniak 191
Index to Volume 44
Glomerulonephritis and parathyroid adenoma ...oliguric ... Jacqueline A. Woolcock and AllenB. Shaw 246
Glucose in 'pancreatic diabetes'-serum-insulinresponse to . . . S. Bank, W. P. U. Jackson,P. Keller and I. N. Marks 212
Glucose tolerance, age and atherosclerosis. K. J.Kingsbury 944
Gluten enteropathy exacerbated by gastro-jejunalanastomosis ... recovery of villous architecturein ... D. G. Weir 234
Granulomatous arteriopathy ... intrahepatic ...H. Fox, M. H. Gleeson and W. F. W. E. Logan 256
Granulosa-cell tumour of the ovary causing sexualprecocity in a girl aged 31 years. Richard H.Parrott 488
Haematoma: presentation and diagnosis on medicalwards . . . subdural . . . M. E. Walker, MichaelEspir and R. H. Shephard 785
Haemochromatosis with particular regard to thepancreatic circulation-arteriography of thecoeliac axis and superior mesenteric artery infive cases of . . . L. A. Scuro, G. Curri, G. Monti,R. Zuin and S. Romani 460
Haemodialysis for carbon tetrachloride poisoning... infectious-mononucleosis-like syndrome fol-lowing... A. T. Proudfoot and R. H. MacDonald 249
Haemolysis . . . the treatment of iron-deficiencyanaemia by iron-dextran infusion, with specialreference to the effect on blood-grouping, coagu-lation, sedimentation and . . . Bernard M.Groden, James Whitelaw and George Will 433
Haemolytic anaemia complicating methyldopatherapy . . . autoimmune . . . Ivor Surveyor,Byron Evans, K. C. Saunders and T. E. Parry 438
Haemorrhage-forearm blood flow and heart rateafter ... 0. G. Edholm and J. D. Hatcher 35
Haemorrhage . . . medical aspects of gastro-intestinal . . . G. N. Chandler 586
Haemorrhage . . . surgical aspects of gastro-intestinal ... C. G. Clark 590
Haemorrhage-pyrexia and elevated erythrocytesedimentation rate in acute gastro-duodenal . . .R. S. Chapman and S. D. Mohamed 238
Hard and soft osteo-arthritis. C. P. Broad 848Heart block in a case of staphylococcal septi-caemia . . . effect of direct-current countershockon atrial flutter with complete . . . JamesBuchanan and Ronald J. Weir 811
Heart disease . . . the value of praecordial pulsa-tions in the diagnosis of ... Patrick Mounsey 81
Heart rate . . . forearm blood flow and-afterhaemorrhage. 0. G. Edholm and J. D. Hatcher 35
Heart size in thyrotoxicosis. J. S. Staffurth andN. D. W. Morrison 885
Hepatic encephalopathy ... the pathogenesis andmedical treatment of . .. A. E. Read 625
Hepatitis ... recent trends in acute viral ... StuartJ. Saunders 102
Hepato-lineal fibrosis without cirrhosis: non-cirrhotic intrahepatic portal hypertension. SheilaSherlock 109
Hernia ... hiatal ... James S. Davidson 579Hernia . . . preoperative diagnosis of strangulated
obdurator hernia . . . Emmanuel QuayeArchampong 140
Herniation into the pericardial sac ... traumatic ...Patrick W. Davis 875
Hiatal hernia. James S. Davidson 579Hormone secretion and associated myopathy ...
carcinoma with multiple ectopic . . . Derek R.Cullen and Bernard E. Tomlinson 472
Hospital . . . the role of the psychiatrist in thegeneral ... A. H. Crisp 267
Human growth hormone . . . standard proceduresfor assessing hypersecretion or secretory capacityfor . . . using the radioimmunoassay. RussellFraser and A. D. Wright 53
Hyperemesis gravidarum . . . a case of acutehyperparathyroidism, with thyrotoxicosis andpancreatitis, presenting as . . . M. A. 0.Soyannwo, M. G. McGeown, M. Bell and T. G.Milliken 861
Hyperglobulinaemia in association with rheuma-toid arthritis and ulcerative colitis ... purpura ...E. N. Wardle 443
Hyperglycaemia-the effect of treatment ofmoderate ... on the incidence of arterial disease.H. Keen, R. J. Jarrett, C. Chlouverakis andD. R. Boyns 960
Hypernephroma . . . sideropenic anaemia withreticulo-endothelial siderosis in a case of . . .
K. Chatterjee and G. E. MacLellan 259Hyperosmolar non-keto-acidotic diabetic coma. A
report of three cases and review of the literature.Anthony Martin 218
Hyperparathyroidism, with thyrotoxicosis andpancreatitis, presenting as hyperemesis gravi-darum. A case of acute ... M. A. 0. Soyannwo,Mary G. McGeown, M. Bell and T. G. Milliken 861
Hypertension, diabetes and atherosclerosis. W. B.Robertson 939
Hypertension ... propranolol in ... S. N. Tewariand R. H. E. Grant 509
Hypersecretion or secretory capacity for humangrowth hormone, standard procedures for assess-ing . . . using the radioimmunoassay. RussellFraser and A. D. Wright 53
Hypertension . . . hepato-lineal fibrosis withoutcirrhosis: non-cirrhotic intrahepatic portal . . .
Sheila Sherlock 109Hypertension, severe, some aspects of the long-term treatment of . . . with methyldopa. M.Hamilton 66
Hyperthyroidism and hypothyroidism . . . bio-chemistry of . .. Frederic L. Hoch 347
Hypertrophic obstructive cardiomyopathy .systolic murmur in . . . and the nature of theobstruction. M. Nellen and M. S. Gotsman 89
Hyperthyroidism . . . the aetiology and patho-genesis of ... Basil S. Hetzel 363
Hypothyroidism . . . biochemistry of hyperthyroid-ism and ... Frederic L. Hoch 347
Hypothyroidism due to enzyme defects. E. M.McGirr and John A. Thomson 398
Vi1
viii Postgraduate Medical Journal
Hypothyroidism in one ofmonozygotic twins. M. C.Moncrieff and R. G. McArthur 423
Incidence and natural history of gastric andduodenal ulcer . . comments on the ... C. N.Pulvertaft 597
Incompetence due to right ventricular papillarymuscle dysfunction ... tricuspid . . . Anne E.Tattersfield 254
Inco-ordination of oesophageal motor activity.M. Atkinson 575
Infancy . . . bone sclerosis in . . . Joan M. R.MacCarthy 908
Infarction ... cardiac aneurysm after myocardial... Bernard M. Groden, Wilson B. James andIan McDicken 775
Infectious diseases: annual review of significantpublications. Hobart A. Reimann 517
Infectious-mononucleosis-like syndrome followinghaemodialysis for carbon tetrachloride poisoning.A. T. Proudfoot and R. H. MacDonald 249
Inherited disease . . . some studies on using thetechniques of cell culture. A. G. Beam 9
Insecticides . . . bilateral retrobulbar neuritis due to... H. E. Jindal 341
Insulin response to glucose in 'pancreatic diabetes'. . serum . . . S. Bank, W. P. U. Jackson, P.Keller and I. N. Marks 212
Insulin antagonism. Synalbumin ... J. Vallance-Owen 117
Intestinal disease . . . protein malnutrition ingastro-... G. Neale 642
Intestinal haemorrhage . . . medical aspects ofgastro-. G. N. Chandler 586
Intestinal haemorrhage . . . surgical aspects ofgastro-... C. G. Clark 590
Intestinal tract . . . autoimmune disease of thegastro-... Ralph Wright 765
Intrahepatic granulomatous arteriopathy. H. Fox,M. H. Gleeson and W. F. W. E. Logan 256
Intrahepatic . . . hepato-lineal fibrosis withoutcirrhosis: non-cirrhotic intrahepatic portal hy-pertension ... Sheila Sherlock 109
Intralobar pulmonary sequestration . . . unusualpresentation of. . . H. B. Lal, A. L. Bahl, S.Mukherjee, P. N. Dhawad and A. K. Sharma 479
Intra-renal arterio-venous fistula with associatedcarcinoma of the kidney. W. J. MacLennan andR. Scott 867
Intravertebral disc . . . a pre- and post-operativestudy of forty-six cases of slipped intervertebraldisc. G. Harto-Garofalidis, Ch. Rigopoulos, N.Papavassiliou and B. T. Papathanassiou 144
Investigation of portal hypertension. M. S.Losowsky 657
Iodine balance in man. Michael T. Harrison 69Iron-deficiency anaemia by iron-dextran, with
special reference to the effect on blood-grouping,coagulation, sedimentation and haemolysis, thetreatment of . . . Bernard M. Groden, JamesWhitelaw and George Will 433
Ischaemic colitis. B. C. Morson 665Jaundice after two years . . . Epping . . . HarryKopelman 78
Joint meniscectomy operation ... a simplication ofthe knee- ... S. S:hwartz 212
'Ketone' level in the diagnosis and treatment ofdiabetic acidosis. M. S. Knapp and Margaret E.Horn 799
Kidney . . . intra-renal arterio-venous fistula withassociated carcinoma of the . .. W. J. Mac-Lennan and R. Scott 867
Kidney: its occurrence in two siblings... medullarycystic disease of the . . . Satya Paul Handa andRobert Tennant 792
Knee-joint meniscectomy operation-a simplifica-tion of the ... S. Schwartz 212
LATS activity, exophthalmos and digital clubbingassociated with myxoedema. Peter Beighton 426
Lead poisoning in childhood. D. Barltrop 537Leukaemia ... Lymphosarcoma during the course
of myeloid ... J. J. Taylor and D. W. Evans 563'Little strokes' ... the differential diagnosis of...John Marshall 543
Liver disease ... the widening spectrum of neuro-logical damage in ... Roger Williams and P. J.Toghill 173
(Loffler's disease)-Endocarditis parietalis fibro-plastica . . . R. C. Jennings and C. D. E.Pengelly 251
Lung ... Regional differences in the... John B.West 120
Lung disease . . . distribution of diffusing capacityin obstructive .. . William A. Briscoe 16
Lung with the carcinoid syndrome . . . a case ofoat-cell carcinoma of the... M. Govindaraj 815
Lymph-nodes after endolymphatic radio-iodine ...
difficulty in clinical assessment of... J. Blake 336Lymphosarcoma during the course of myeloidleukaemia... J. J. Taylor and D. W. Evans 563
Major vascular complications in Behcet's syn-drome. H. Anthony Enoch, J. L. Castillo-Olivares, T. C. L. Khoo, R. G. Grainger andL. Henry 453
Malnutrition in gastro-intestinal disease . . .
protein . . . G. Neale 642Measurement of personality and attitude: applica-
tions to clinical research. Isaac Marks 277Mediators . . . chemical in the central nervoussystem ... P. K. Lahiri and P. Sen 167
Medical aspects of gastro-intestinal haemorrhage.G. N. Chandler 586
Medical treatment of hepatic encephalopathy ...the pathogenesis and ... A. E. Read 652
Medullary cystic disease of the kidney: its occur-rence in two siblings. Satya Paul Handa andRobert Tennant 792
Melkersson's syndrome-observations on . . .
George A. Scott 447Meningitis ... experiences with carbenicillin in the
treatment of septicaemia and ... A. E. Richard-son, C. R. Spittle, K. W. James and 0. P. W.Robinson 844
Meningitis due to Streptococcus agalactiae . . .
neonatal . . . H. Everley Jones and C. H. L.Howells 549
Index to Volume 44ix
Meniscectomy operation ... a simplification of theknee-joint. S. Schwartz 212
Mercury . . . failure of folic acid to influencemortality of rats with acute tubular necrosiscaused by ... I. Taraba and G. M. Bull 116
Mesenteric arteriography ... pancreatic and ...E. Herlinger 755
Mesenteric artery in five cases ofhaemochromatosiswith particular regard to the pancreatic circula-tion. Arteriography of the coeliac and superior...L. A. Scuro, G. Curri, G. Monti, R. Zuin andS. Romani 460
Metabolic bone disease . . . gastric resection and. . C. N. Pulvertaft 618
Metabolism of angiotensin-studies on the . . .
Austin E. Doyle 31Metabolism of vitamin D after gastric surgery ...
studies in the absorption and . . . Gilbert R.Thompson 626
Metabolism . . . the regulation of cholesterol ...
N. B. Myant 86Metacarpal ... non-union of a fractured fifth ...
C. P. Broad 819Metyrapone on steroid production by a patient
with a corticotrophin secreting bronchogeniccarcinoma ... effects of different regimes of...Judith M. Steel and A. A. H. Lawson 485
McMichael . . . Festschrift for Sir John. C. E.Newman 5
Methyldopa . . . some aspects of the long-termtreatment of severe hypertension with . . .
M. Hamilton 66Methyldopa therapy. Autoimmune haemolyticanaemia complicating ... Ivor Surveyor, ByronEvans, K. C. Saunders and T. E. Parry 438
Mitotic drugs ... a medical emergency treated byanti-... W. S. B. Lowry 926
Mitral regurgitation in congestive cardiomyopathy.J. F. Goodwin 62
Mononucleosis-like syndrome following haemo-dialysis for carbon tetrachloride po:soning . . .
infectious . . . A. R. Proudfoot and R. H.MacDonald 249
Monozygotic twins ... hypothyroidism in one of... M. W. Moncrieffand R. G. McArthur 423
Motility studies to gastroenterological problems ...
the application of ... J. J. Misiewicz 749Motor activity ... inco-ordination of oesophageal
... M. Atkinson 575Multisystem interests . . . John McMichael's ...D. Geraint James and 0. P. Sharma 71
Murmur... systolic... in hypertrophic obstructivecardiomyopathy and the nature of the obstruc-tion. M. Nellen and M. S. Gotsman 89
Muscle disease ... thyrotoxic ... Ian Ramsay 385Muscle dysfunction ... tricuspid incompetence due
to right ventricular papillary . . . Anne E.Tattersfield 254
Muscle necrosis and acute renal failure in carbonmonoxide poisoning ... A. L. Linton, J. HumeAdams and D. H. Lawson 338
Muscle . .. studies on the action of bronchi l ...John Crofton 26
Myeloid leukaemia ... lymphosarcoma during thecourse of... J. J. Taylor and D. W. Evans 563
Myelomatosis ... the management of... A. F.Broad, E. W. Emery, J. N. Godlee and T. A. J.Prankerd 803
Myocardial infarction ... cardiac aneurysm after. . Bernard M. Groden, Wilson B. James andIan McDicken 775
Myopathy... Carcinoma with multiple ectopic hor-mone secretion and associated . . . Derek R.Cullen and Bernard E. Tomlinson 472
Myxoedema. LATS activity, exophthalmos anddigital clubbing associated with . . . PeterBeighton 246
Nasopharynx . . . contrast radiography of the ...
Gordon Evison 825Natural history and treatment ... Crohn's disease
... J. E. Lennard-Jones 674Natural history of gastric and duodenal ulcers ...comments on the incidence and . . . C. N.Pulvertaft 597
Necrosis... analgesic nephropathy and papillary ...
Priscilla Kincaid-Smith 807Necrosis and acute renal failure in carbon mon-
oxide poisoning . . . muscle . . . A. L. Linton,J. Hume Adams and D. H. Lawson 338
Necrosis . . . failure of folic acid to influencemortality of rats with acute tubular ... causedby mercury. I. Taraba and G. M. Bull 116
Neonatal meningitis due to Streptococcus agalactiae.H. Everley Jones and G. H. L. Howells 549
Neonatal period . . . anhidrotic ectodermal dys-plasia presenting as a pyrexia of undeterminedorigin in the... J. Mills 193
Nephropathy and papillary necrosis ... analgesic... Priscilla Kincaid-Smith 807
Nephropathy and viroses. Hobart A. Reimann 844Nephrotic syndrome in Idaban, Nigeria: a pros-
pective study of 135 cases . . . adult ... 0. 0.Akinkugbe and Mollie Hunton 903
Neuritis due to insecticides . . . bilateral retro-bulbar... H. R. Jindal 341
Neurological damage in liver disease . . . thewidening spectrum of... Roger Williams andP. J. Toghill 173
Neurosyphilitic psychoses ... clinico-pathologicalaspects of the ... Kenneth Dewhurst 898
Non-union of a fractured fifth metacarpal... C. P.Broad 819
Oat-cell carcinoma of the lung with the carcinoidsyndrome ... a case of... M. Govindaraj 815
Obesity . . . total fasting in the treatment of...I. C. Gilliland 58
Observations on Melkersson's syndrome. GeorgeA. Scott 447
Obstruction due to an anomalous portal vein ...duodenal... V. V. Kakkar and A. M. B. Tomp-kin 189
Obstructive cardiomyopathy . . . the systolicmurmur in ... and the nature of the obstruction.M. Nellen and M. S. Gotsman 89
Obturator hernia . . . preoperative diagnosis ofstrangulated ... Emmanuel Quaye Archampong 140
x Postgraduate Medical Journal
Oesophageal foreign bodies and their complications... the management of ... R. J. Donnelly andP. B. Deverall 830
Oesophagus-'Spontaneous' rupture of the healthy... P. J. Toghill, C. F. MacGuire and P. S. Raut 504
Oliguric glomerulonephritis and parathyroid ade-noma. Jacqueline A. Woolcock and Allen B.Shaw 246
Oliver and Schafer's discovery of the cardiovascularaction of suprarenal extract. H. Barcroft andJ. F. Talbot 6
Oesophageal motor activity ... inco-ordination of... M. Atkinson 575
Oesophageal pain. John R. Bennett 571Osteo-arthritis ... hard and soft. C. P. Broad 848Osteomalacia and osteoporosis. D. B. Morgan 621Osteoplastica... tracheopathia. H. P. Gautam 186Osteoporosis . . . osteomalacia and . . . D. B.Morgan 621
Osteosclerosis . . . primary Raynaud's diseaseassociated with sclerodactyly and digital . . .
D. W. Golding and H. Baker 553Ovary causing sexual precocity in a girl aged 34
years . . . granulosa-cell tumour of the . . .
Richard H. Parrott 488Oxford study-blood sugars, vascular abnormali-
ties and survival-the Oxford Study after 17years. J. B. O'Sullivan, J. Cosgrove and D.McCaughan 955
Pain ... oesophageal... John R. Bennett 571Pain ... psychological aspects of... H. Merskey 297Pancreatic circulation. Arteriopathy of the coeliac
axis and superior mesenteric artery in five casesof haemochromatosis with particular regard tothe... L. A. Scuro, G. Curri, R. Zuin, S. Romaniand G. Monti 460
Pancreatic and mesenteric arteriography. E.Herlinger 755
Pancreatic disease: surgical aspects. A. V. Pollock 737Pancreatitis: medical aspects . . . chronic . . .
Henry T. Howat 733Pancreatitis, presenting as hyperemesis gravi-darum ... a case of acute hyperparathyroidism,with thyrotoxicosis and ... M. A. O. Soyannwo,M. G. McGeown, M. Bell and T. G. Milliken 861
Pancreatitis ... the pathogenesis of gallstone ...J. E. Trapnell 497
Parathyroid adenoma . . . oliguric glomerulone-phritis and . . . Jacqueline A. Woolcock andAllen B. Shaw 246
'Pancreatic diabetes' . . . serum-insulin response toglucose in . . . S. Hank, W. P. U. Jackson, P.Keller and I. N. Marks 212
Pancreas .. . Cushing's syndrome associated withcarcinoma of . . . B. A. Enoch and D. M.Williams 925
Papillary necrosis . . . analgesic nephropathy . ..Priscilla Kincaid-Smith 807
Pathogenesis of hyperthyroidism ... the aetiologyand... Basil S. Hetzel 363
Pathological aspects of the neurosyphilitic psy-choses ... clinico-... Kenneth Dewhurst 898
Penetrating injuries of the abdomen and thorax ...
stab-wounds and other. J. B. Garland 127Penicillin encephalopathy. N. Conway, E. Beckand Jane Somerville 891
Peptic ulcer ... the surgical treatment of... Iain E.Gillespie 608
Peptide-secreting adenomata with special referenceto the Zollinger-Ellison syndrome. W. Sircus 742
Pericardial sac . . . traumatic herniation intothe... Patrick W. Davis 875
Peripheral vascular disease . . . gas gangrene afteramputation for ... I. G. Schraibman 551
Pernicious anaemia ... diabetes mellitus, Addison'sdisease ... R. C. Turner and Arnold Bloom 555
Personality and attitude: applications to clinicalresearch ... measurements of... Isaac Marks. 277
Phenformin as a fibrinolytic drug. G. R. Fearley 468Phosphate excretion ... a modified index of...
B. E. C. Nordin and L. Bulusu 93Plasma 'ketone' level in the diagnosis and treatmentof diabetic acidosis. M. S. Knapp and MargaretE. Horn 799
Pneumonic aspergillosis complicating healed tuber-culosis. E. Freeman 181
Poisoning-infectious-mononucleosis-like syn-drome following haemodialysis for carbon tetra-chloride. A. T. Proudfoot and R. H. MacDonald 249
Poisoning in childhood-lead-. D. Barltrop 537Poisoning-muscle necrosis and acute renal failure
in carbon monoxide ... A. L. Linton, J. HumeAdams and D. H. Lawson 338
Portal hypertension-hepato-lineal fibrosis withoutcirrhosis: non-cirrhotic intrahepatic. SheilaSherlock 109
Portal hypertension ... investigation of... M. S.Losowsky 657
Portal vein... duodenal obstruction due to an ano-malous ... V. V. Kakkar and A. M. B. Tompkin 189
Praecordial pulsations in health and disease.Patrick Mounsey 134
Praecordial pulsations in the diagnosis of heartdisease ... the value of... Patrick Mounsey 81
Precocity in a girl aged 34 years . . granulosa-celltumour of the ovary causing sexual ... RichardParrott 488
Pregnancy-renal disease in. K. F. Fairley andPriscilla Kincaid-Smith 45
Pregnant immigrants . . . sickle-cell disease in ...A. E. R. Buckle 836
Preoperative diagnosis of strangulated obturatorhernia. Emmanuel Quaye Archampong 140
Pre-operative sedatives-a study of . . . JamesParkhouse and Jean Mahoney 229
Present treatment of breast cancer. J. L. Grogono 501Primary Raynaud's disease associated with schlero-
dactyly and digital osteosclerosis. D. B. Goldingand H. Baker 553
Propranolol in hypertension. S. N. Tewari andR. H. E Grant 509
Protein malnutrition in gastro-intestinal disease.G. Neale 642
Psychiatric aspects of epilepsy. Donald F. Scott 319Psychiatrist in the general hospital-the role ofthe... A. H. Crisp 267
Index to Volume 44 xi
Psychiatry-recent progress in epidemiological.Brian Cooper 331
Psychological aspects of geriatrics. Felix Post 307Psychological aspects of pain. H. Merskey 297Psychoses . . . clinico-pathological aspects of the
neuro-syphilitic. Kenneth Dewhurst 898Psychotropic drugs. John Hinton 286Pulmonary aspergillosis in two families. R. H.
Ellis 178Pulmonary embolism. The surgical treatment of
acute massive ... H. P. Gautam 917Pulmonary sequestration ... unusual presentation
of intralobar . . . H. B. Lal, A. L. Vahl, S.Mukherjee, P. N. Dhawad, A. K. Sharma andG. S. Sarin 479
Pulsations in health and disease-praecordial ...Patrick Mounsey 134
Pulsations in the diagnosis of heart disease ... thevalue of praecordial. Patrick Mounsey 81
Purpura hyperglobulinaemia in association withrheumatoid arthritis and ulcerative colitis. E. N.Wardle 443
Pyrexia and elevated erythrocyte sedimentation ratein acute gastro-duodenal haemorrhage. R. S.Chapman and S. D. Mohamed 238
Pyrexia of undetermined origin in the neonatalperiod. Anhidrotic ectodermal dysplasia pre-senting as a ... J. Mills 193
Radiography of the nasopharynx . . . contrast.Gordon Evison 825
Radioimmunoassay. Standard procedures forassessing. Russell Fraser and A. D. Wright 53
Radio-iodine-difficulty in clinical assessment oflymph-nodes after endolymphatic. J. Blake 336
Rats-failure of folic acid to influence mortalityof . . . with acute tubular necrosis caused bymercury. I. Taraba and G. M. Bull 116
Raynaud's disease associated with schlerodactylyand digital osteosclerosis ... Primary ... D. N.Golding and H. Baker 553
Recent progress in epidemiological psychiatry.Brian Cooper 331
Recovery of villous architecture in gluten entero-pathy exacerbated by gastro-jejunal anastomosis.D. G. Weir 234
Regional differences in the lung. John B. West 120Regurgitation, mitral-in congestive cardiomyo-
pathy. J. F. Goodwin 62Renal arterio-venous fistula with associated carci-noma of the kidney. Intra- ... W. J. MacLennanand R. Scott 867
Renal artery stenosis due to abdominal aorticaneurysm. M. N. Lowenthal, S. A. Doctor andJ. Fine 928
Renal disease in pregnancy. K. F. Fairley andPriscilla Kincaid-Smith 45
Renal failure in carbon monoxide poisoning-muscle necrosis and acute . . . A. L. Linton,J. Hume Adams and D. H. Lawson 338
Repeated samples of fat obtained with a biopsyneedle. C. G. Hunter and R. R. Kendrick 852
Research-measurements of personality and atti-tude: applications to clinical. . . Isaac Marks 277
Resection and metabolic bone disease . . . gastricC. N. Pulvertaft 618
Reticulo-endothelial siderosis in a case of hyper-nephroma sideropenic anaemia with ... K. Chat-terjee and G. F. MacLellan 259
Retrobulbar neuritis due to insecticides . . . bi-lateral... H. R. Jindal 341
Rheumatoid arthritis and ulcerative colitis. Purpurahyperglobulinaemia in association with ... E. N.Wardle 443
Rhinolith. A brief review of the literature and acase report. P. T. Marfatia 478
Right ventricular papillary muscle dysfunction-tricuspid incompetence due to . . . Ann E.Tattersfield 254
Rupture of the healthy oesophagus-'spontaneous'... P. J. Toghill, C. F. Maguire and P. S. Raut 504
Sarcoidosis-A 'burnt-out' case of . . . J. G.S:adding 105
Schafer's (and Oliver) discovery of the cardio-vascular action of suprarenal extract. H. Barcroftand J. E. Talbot 6
Sclerodactyly and digital osteosclerosis ... primaryRaynaud's disease associated with . . . D. N.Golding and H. Baker 553
Sclerosis in infancy . . . bone . . . Joan M. R.MacCarthy 908
Secretory capacity for human growth hormone-standard procedures for assessing hypersecretionor . . . using the radioimmunoassay. RussellFraser and A. D. Wright 53
Sedimentation, haemolysis, the treatment of irondeficiency anaemia by iron-dextran infusion,with special reference to the effect on blood-grouping, coagulation ... Bernard M. Groden,James Whitelaw and George Will 433
Sedatives-a study of pre-operative . . . JamesParkhouse and Joan Mahoney 229
Septicaemia and meningitis . . . experience withcarbenicillin in the treatment of . . . A. E.Richardson, C. R. Spittle, K. W. James andO. P. W. Robinson 844
Sequestration . . . unusual presentation of intra-lobar pulmonary ... H. B. Lal, A. L. Bahl, S.Mukherjee, P. N. Dhawad, A. K. Sharma andG. S. S rin 479
Serum cholesterol levels in anorexia nervosa. L. M.Blendis and A. H. Crisp 327
Serum-insulin response to glucose in 'pancreaticdiabetes'. S. Bank, W. P. U. Jackson, P. Kellerand I. N. Marks 214
Sexual precocity in a girl aged 31 years . . . granu-losa-cell tumour of the ovary causing . ..
Richard H. Parrott 488Sickle-cell disease in pregnant immigrants. A. E. R.Buckle 836
Sideropenic anaemia with reticulo-endothelialsiderosis in a case of hypernephroma. K.Chatterjee and G. E. MacLellan 259
Slipped intervertebral disc. A pre- and post-opera-tive study of 46 cases of... G. Harto-Garofalidis,Ch. Rigopoulos, N. Papavassiliou and B. T.Papathanassiou 144
xii Postgraduate Medical Journal
Spatial vectorcardiogram in diagnosis. D. Emslie-Smith and K. G. Lowe 39
'Spontaneous' rupture of the healthy oesophagus.P. J. Toghill, C. F. Macguire and P. S. Raut 504
Stab-wounds and other penetrating injuries of theabdomen and thorax. J. B. Garland 127
Stenosis due to abdominal aortic aneurysm. Renalartery ... M. N. Lowenthal, S. A. Doctor andJ. Fine 928
Steroid production by a patient with a corticotrophinsecreting bronchogenic carcinoma . . . effectsof different regimes of metyrapone on ... JudithM. Steel and A. A. H. Lawson 485
Strangulated obturator hernia-preoperative diag-nosis of... Emmanuel Quaye Archampong 140
Streptococcus agalactiae . . . neonatal meningitisdue to ... H. Everley Jones and C. H. L. Howells 549
Studies in the absorption and metabolism ofvitaminD after gastric surgery. Gilbert R. Thompson 626
Subdural haematoma: presentation and diagnosison medical wards. M. E. Walder, Michael Espirand R. H. Shephard 785
Sugars-blood-, vascular abnormalities andsurvival-the Oxford study after 17 years. J. B.O'Sullivan, J. Cosgrove and D. McCaughan 955
Superior mesenteric artery in five cases of haemo-chromatosis with particular regard to thepancreatic circulation-arteriography of thecoeliac axis and ... L. A. Scuro, G. Curri, G.Monti, R. Zuin and S. Romani 460
Suprarenal extract-Oliver and Schafer's discoveryof the cardiovascular action of. H. Barcroft andJ. E. Talbot 6
Surgeon's viewpoint. R. C. F. Catterall 969Surgery . . . studies in the absorption and metabo-
lism of vitamin D after gastric . . . Gilbert R.Thompson 626
Surgery . . . the late results of gastric . . . C. N.Pulvertaft 613
Surgical aspects of gastro-intestinal haemorrhage.C. G. Clark 590
Survival-blood sugars, vascular abnormalities and. . . the Oxford study after 17 years. J. B.O'Sullivan, J. Cosgrove and D. McCaughan 955
Synalbumin insulin antagonism. J. Vallance-Owen 117Systolic murmur in hypertrophic obstructive cardio-myopathy and the nature of the obstruction.M. Nellen and M. S. Gotsman 89
Teratoma-gastric. S. R. Meadow 183Tetracycline ... a death from. Gillian C. Hanson 870The aetiology and pathogenesis of hyperthyroidism.
Basil S. Hetzel 363The application of motility studies to gastroentero-
logical problems. J. J. Misiewicz 749The different diagnosis of 'little strokes'. John
Marshall 543The irritable colon syndrome. A. M. Connell 668The late results of gastric surgery. C. N. Pulvertaft 613The management of myelomatosis. A. F. Broad,
E. W. Emery, J. N. Godlee and T. A. J.Prankerd 803
The management of oesophageal fo reign bodies andtheir complications. R. J. Donnelly, andP. B. Deverall 830
The medical treatment of gastric and duodenalulcer. M. J. S. Langman 603
The medical treatment of ulcerative colitis.Geoffrey Watkinson 696
The pathogenesis and medical treatment of hepaticencephalopathy. A. E. Read 652
The pathogenesis of gallstone pancreatitis. J. E.Trapnell 497
The role of the psychiatrist in the general hospital.A. H. Crisp 267
The surgical treatment of peptic ulcer. Iain E.Gillespie 608
The surgical treatment of acute massive pulmonaryembolism. H. P. Gautam 917
The surgical treatment of ulcerative colitis. J. C.Goligher 708
The systemic complications of ulcerative colitis.Geoffrey Watkinson 693
The treatment of iron-deficiency anaemia by iron-dextran infusion, with special reference to theeffect on blood grouping, coagulation, sedimenta-tion and haemolysis. Bernard M. Groden, JamesWhitelaw and George Will 433
The uses of biguanides in diabetes mellitus. H. Keenand R. J. Jarrett 466
The widening spectrum of neurological damage inliver disease. Roger Williams and P. J. Toghill 173
Thorax-stab wounds and other penetrating in-juries of the abdomen and . . . J. B. Garland 127
Thyroid and adrenal relationships. Victor Parsonsand Ian Ramsay 377
Thyroid carcinoma and its treatment. SelwynTaylor 404
Thyroid function-the Achilles tendon reflex as anindex of... George Nuki and R. I. S. Bayliss 97
Thyrotoxic muscle disease. Ian Ramsay 385Thyrotoxicosis . . . an association betweenWericke's encephalopathy and ... B. A. Enochand D. M. Williams 923
Thyrotoxicosis and pancreatitis, presenting ashyperemesis gravidarum . . . a case of acutehyperparathyroidism with . . . M. A. O.Soyannwo, M. G. McGeown, M. Bell and T. G.Milliken 861
Thyrotoxicosis ... heart size in ... J. S. Staffurthand N. D. W. Morrison 885
Tracheopathia osteoplastica. H. P. Gautam 186Traumatic herniation into the pericardial sac.
Patrick W. Davis 875Tricuspid incompetence due to right ventricular
papillary muscle dysfunction. Anne E. Tattersfield 254Tubal stump-ectopic gestation in ... S. Krzaniak 191Tuberculosis-pneumonic aspergillosis complicat-
ing healed ... E. Freeman 181Tubular, acute-insufficiency. A. M. Joekes 75Tubular-failure of folic acid to influence mortality
of rats with acute... necrosis caused by mercury.I. Taraba and G. M. Bull 116
Tumour of the ovary causing sexual precocity in agirl aged 3J years ... granulosa cell ... RichardH. Parrott 488
Index to Volume 44 xiii
Twins-Hypothyroidism in one of monozygotictwins... M. W. Moncrieff and R. G. Arthur 423
Ulcerative colitis: definition, historical background,aetiology, diagnosis, natural history and localcomplications. F. T. de Dombal 684
Ulcerative colitis-purpura hyperglobulinaemiain association with rheumatoid arthritis and ...E. N. Wardle 433
Ulcerative colitis-The medical treatment of ...Geoffrey Watkinson 696
Ulcerative colitis ... the surgical treatment of...J. C. Goligher 708
Ulcerative colitis ... the systemic complications of. . Geoffrey Watkinson 693
Ulcer ... comments on the incidence and naturalhistory of gastric and duodenal . . . C. N.Pulvertaft 597
Ulcer . . . the medical treatment of gastric andduodenal... M. J. S. Langman 603
Ulcer... the surgical treatment of peptic... Iain E.Gillespie 608
Unusual method of diagnosis in a new case ofbenign duodenocolic fistula . . . J. H. P.Cuddigan and M. A. Edgar 481
Unusual presentation of intralobar pulmonarysequestration. H. B. Lal, A. B. Bahl, S.Mukherjee, P. N. Dhawad, A. K. Sharma andG. S. Sarin 479
Vascular abnormalities-blood sugars-and sur-vival-the Oxford study after 17 years. J. B.O'Sullivan, J. Cosgrove and D. McCaughan 955
Vascular complications in Behget's syndrome ...
major . . . B. Anthony Enoch, J. L. Castillo-Olivares, T. C. Khoo, R. G. Grainger and L.Henry 453
Vascular disease-gas gangrene after amputation forperipheral. I. G. Schraibman 551
Vectorcardiogram-spatial-in diagnosis. D.Emslie-Smith and K. G. Lowe 39
Venous fistula with associated carcinoma of thekidney-intra-renal arterio- . . . W. J. Mac-Lennan and R. Scott 867
Villous architecture in gluten enteropathy exacer-bated by gastro-jejunal anastomosis. D. G. Weir 1234
Viral hepatitis-recent trends in acute ... Stuart J.Saunders 102
Viroses . . . nephropathy and . . . Hobart A.Reimann 844
Vitamin D after gastric surgery-studies in theabsorption and metabolism of . . . G. R.Thompson 626
Wemicke's encephalopathy and thyrotoxicosis ...an association between . . . B. A. Enoch andD. M. Williams 923
Zollinger-Ellison syndrome ... peptide-secretingadenomata with special reference to the . . .
W. Sircus 742
Author IndexPage
Akinkugbe, 0.0. (and Hunton, Mollie): Adultnephrotic syndrome in Ibadan, Nigeria: a pros-pective study of 135 cases 903
Archampong, E.Q.: Preoperative diagnosis ofstrangulated obturator hernia 104
Atkinson, M.: Inco-ordination of oesophagealmotor activity 575
Bahl, A.L., (Lal, H.B., Chugh, R.N., Mathur, K.P.and Bhalla, A.S.): Clinical patterns and complica-tions of diabetes mellitus in India 223
Bahl, A.L., (Lal, H.B., Mukherjee, S., Dhawad,P.N., Sharma, A.K. and Sarin G.S.): Unusualpresentation of intralobar pulmonary sequestra-tion 479
Baker, H. (and Golding, D.N.): Primary Raynaud'sdisease associated with sclerodactyly and digitalosteosclerosis 553
Balmer, G.A., (Phillips, R.S. and Monk, C.J.E.):A plea for simplicity in the classification ofankle fractures 199
Bank, S., (Jackson, W.P.U., Keller, P. and Marks,I.N.): Serum-insulin response to glucose in'Pancreatic diabetes' 214
Barcroft, H. (and Talbot, J.F.): Oliver andSchafer's discovery of the cardiovascular actionof suprarenal extract 6
Barltrop, D.: Lead poisoning in childhood 537Bayliss, R.I.S. (and Nuki, G.): The Achilles tendon
reflex as an index of thyroid function 97
PageBeam, A.G.: Some studies on inherited disease
using the techniques of cell culture 9Beck, E., (Conway, N. and S :merville, J.): Penicillin
encephalopathy 891Beighton, P.: LATS activity, exophthalmos and
digital clubbing associated with myxoedema 426Bell, M., (Soyannwo, M.A.O., McGeown, M.G.and Milliken, T.G.): A case of acute hyperpara-thyroidism, with thyrotoxicosis and pancreatitis,presenting as hyperemesis gravidarum 861
Bennett, J.R.: Oesophageal pain 571Bhalla, A.S., (Lal, H.B., Bahl, A.L., Chugh, R.N.and Mathur, K.P.): Clinical patterns and com-plications of diabetes mellitus in India 223
Blake, J.: Difficulty in clinical assessment oflymph-nodes after endolymphatic radio-iodine 336
Blendis, L. M. (and Crisp, A.H.): Serum cholesterollevels in anorexia nervosa 237
Bloom, A. (and Turner, R.C.): Diabetesmellitus, Addison's disease and perniciousanaemia 555
Booth, C.C.: Enteropoiesis: structural and func-tional relationships of the enterocyte 12
Boyns, D.R., (Keen, H., Jarrett, R.J. andChlouverakis, C.): The effect of treatment ofmoderate hyperglycaemia on the incidence ofarterial disease 960
Briscoe, W.A.: Distribution of diffusing capacityin obstructive lung disease 16
xiv Postgraduate Medical Journal
Broad, A.F., (Emery, E.W., Godlee, J.N. andPrankerd, T.A.J.): The management of myelo-matosis 803
Broad, C.P.: Non-union of a fractured fifth meta-carpal 817
Broad, C.P.: Hard and soft osteo-arthritis 848Buchanan, J. (and Weir, R.J.): Effect of direct-
current countershock on atrial flutter withcomplete heart block in a case of staphylococcalsepticaemia 811
Buckle, A.E.R.: Sickle-cell disease in pregnantimmigrants 836
Bull, G.M. (and Taraba, I.): Failure of folic acidto influence mortality of rats with acute tubularnecrosis caused by mercury 116
Bulusu, L. (and Nordin, B.E.C.): A modified indexof phosphate excretion 93
Bywaters, E.G.L.: The Cheshire Cat Syndrome 19
Campbell, E.J.M., (Fletcher, C.M. and Jones,N.L.): Research into bronchitis and emphysema 48
Castillo-Olivares, J.L., (Enoch, B.A., Khoo,T.C.L., Grainger, R.G. and Henry, L.): Majorvascular complications in Behcet's syndrome 453
Catterall, R.C.F.: The surgeon's viewpoint 969Chandler, G.N.: Medical aspects of gastro-intestinalhaemorrhage 586
Chapman, R.S. (and Mohamed, S.D.): Pyrexiaand elevated erythrocyte sedimentation rate inacute gastro-duodenal haemorrhage 238
Chatterjee, K. (and MacLellan, G.E.): Sideropenicanaemia with reticulo-endothelial siderosis in acase of hypernephroma 259
Chlouverakis, C., (Keen, H., Jarret, R.J. andBoyns, D.R.): The effect oftreatment ofmoderatehyperglycaemia on the incidence of arterialdisease 960
Chugh, R.N., (Lal, H.B., Bahl, A.L., Mathur,K.P. and Bhalla, A.S.): Clinical patterns andcomplications of diabetes mellitus in India 223
Clark, C.G.: Surgical aspects of gastro-intestinalhaemorrhage 590
Connell, A.M.: The irritable colon syndrome 668Conway, N., (Beck, E. and Somerville, J.):
Penicillin encephalopathy 891Cooper, B.: Recent progress in epidemiological
psychiatry 331Cope, C.L. (and Mattingly D.): Some recent
advances in adrenal diagnosis 23Cosgrove, J., (O'Sullivan, J.B. and McCaughan,
D.): Blood sugars, vascular abnormalities andsurvival-the Oxford study after 17 years 955
Crisp, A.H.: The role of the psychiatrist in thegeneral hospital 267
Crisp, A.H. (and Blendis, L.M.): Serum cholesterollevels in anorexia nervosa 327
Crofton, J.: Studies on the action of bronchialmuscle 26
Cuddigan, J.H.P. (and Edgar, M.A.): Unusualmethod of diagnosis in a new case of benignduodenocolic fistula 481
Cullen, D.R. (and Tomlinson, B.E.): Carcinomawith multiple ectopic hormone secretion andassociated myopathy 472
Curri, G., (Scuro, L.A., Monti, G., Zuin, R.and Romani, S.): Arteriography of the coeliacaxis and superior mesenteric artery in five casesof haemochromatosis with particular regard tothe pancreatic circulation 460
Davidson, J.S.: Hiatal hernia 579Davis, P.W.: Traumatic herniation into the
pericardial sac 875Dawson, A.M.: Disaccharidase deficiency in man 646De Dombal, F.T.: Ulcerative colitis: definition,
historical background, aetiology, diagnosis,natural history and local complications 684
Deverall, P.B. (and Donnelly, R.J.): The manage-ment of oesophageal foreign bodies and theircomplications 830
Dewhurst, K.: Clinico-pathological aspects of theneurosyphilitic psychoses 898
Dhawad, P.N., (Lal, H.B., Bahl, A.L., Mukherjee,S., Sharma, A.K. and Sarin, G.S.): Unusualpresentation of intralobar pulmonary sequestra-tion 479
Doctor, S.A., (Lowenthal, M.N. and Fine, J.):Renal artery stenosis due to abdominal aorticaneurysm 928
Dollery, C.T.: The formation of collaterals 28Donaldson, I.A. (and Bismillah, A.H.): Life from
a couvelaire uterus 356Donnelly, R.J. (and Deverall, P.B.): The manage-ment of oesophageal foreign bodies and theircomplications 830
Doyle, A.E.: Studies on the metabolism of angio-tensin 31
Edholm, O.G. (and Hatcher, J.D.): Forearm bloodflow and heart rate after haemorrhage 35
Edgar, M.A. (and Cuddigan, J.H.P.): Unusualmethod of diagnosis in a new case of benignduodenocolic fistula 481
Ellis, R.H.: Pulmonary aspergillosis in two families 179Emery, E.W., (Broad, A.F., Godlee, J.N. and
Prankerd, T.A.J.): The management ofmyeloma-tosis 803
Enoch, B.A., (Castillo-Olivares, J.L., Khoo,T.C.L., Grainger, R.G. and Henry, L.): Majorvascular complications in Behcet's syndrome 453
Enoch, B.A. (and Williams, D.M.): An associationbetween Wericke's encephalopathy and thyro-toxicosis 923
Espir, M., (Walker, M.E. and Shephard, R.H.):Subdural haematoma: presentation and diagnosison medical wards 785
Evans, B., (Surveyor, I., Saunders, K.C. andParry, T.E.): Autoimmune haemolytic anaemiacomplicating methyldopa therapy 438
Evans, D.W. (and Taylor, J.J.): Lymphosarcomaduring the course of myeloid leukaemia 558
Everley Jones, H. (and Howells, C.H.L.): Neonatalmeningitis due to Streptococcus agalactiae 549
Evison, G.: Contrast radiography of the naso-pharynx 825
Fairley, K.F. (and Kincaid-Smith, P.): Renaldisease in pregnancy 45
Feamley, G.R.: Phenformin as a fibrinolytic drug 468
Index to Volume 44 xv
Fine, J. (Lowenthal, M.N. and Doctor, S.A.):Renal artery stenosis due to abdominal aorticaneurysm 928
Fletcher, C.M., (Jones, N.L. and Campbell,E.J.M.): Research into bronchitis and em-physema 48
Foster, G.V.: Calcitonin: A review of experimentaland clinical investigations 411
Fox, H., (Gleeson, M.H. and Logan, W.F.W.E.):Intrahepatic granulomatous arteriopathy 256
Fraser, R. (and Wright, A.D.): Standard pro-cedures for assessing hypersecretion or secretorycapacity for human growth hormone, using theradioimmunoassay 53
Freeman, E.: Pneumonic aspergillosis complicatinghealed tuberculosis 181
Garland, J.B.: Stab-wounds and other penetratinginjuries of the abdomen and thorax 127
Gautam, H.P.: Tracheopathia osteoplastica 186Gillespie, I.E.: The surgical treatment of peptic
ulcer 608Gilliland, I.C.: Total fasting in the treatment of
obesity 58Gleeson, M.H., (Fox, H. and Logan, W.F.W.E.):
Intrahepatic granulomatous arteriopathy 256Golding, D.N. (and Baker, H.): Primary Raynaud's
disease associated with sclerodactyly and digitalosteosclerosis 553
Godlee, J.N., (Broad, A.F., Emery, E.W. andPrankerd T.A.J.): The management of myelo-matosis 803
Goligher, J.C.: The surgical treatment of ulcera-tive colitis 708
Goodwin, J.F.: Mitral regurgitation in congestivecardiomyopathy 62
Gotsman, M.S. (and Nellen, M.): The systolicmurmur in hypertrophic obstructive cardiomyo-pathy and the nature of the obstruction 89
Govindaraj, M.: A case of oat-cell carcinoma ofthe lung with the carcinoid syndrome 815
Grainger, R.G., (Enoch, B.A., Castillo-Olivares,J.L., Khoo, T.C.L. and Henry, L.): Majorvascular complications in Behcet's syndrome 453
Grant, R.H.E. (and Tewari, S.N.): Propranolol inhypertension 509
Groden, B.M., (James, W.B. and McDicken, I.):Cardiac aneurysm after myocardial infarction 775
Groden, B.M., (Whitelaw, J. and Will, G.): Thetreatment of iron-deficiency anaemia by iron-dextran infusion, with special reference to theeffect on blood grouping, coagulation, sedimen-tation and haemolysis 433
Grogono, J.L.: Present treatment of breast cancer 501Gautam, H.P.: The surgical treatment of acute
massive pulmonary embolism 917
Hadley, G.D.: The gastrocamera 763Hamilton, M.: Some aspects of the long-term
treatment ofsevere hypertension with methyldopa 66Handa, S.P. (and Tennant, R.): Medullary cystic
disease of the kidney: its occurrence in twosiblings 792
Hanson, G. C.: A death from tetracycline 870
Harrison, M.T.: Iodine balance in man 69Harto-Garofalidis, G., (Rigopoulos, C., Papavas-
siliou, N. and Papathanassiou, B.T.): A pre- andpost-operative study of forty-six cases of slippedintervertebral disc 144
Hatcher, J.D. (and Edholm, O.G.): Forearm bloodflow and heart rate after haemorrhage 35
Henderson, W.: Constipation in childhood 724Henry, L., (Enoch, B.A., Castillo-Olivares, J.L.,Khoo, T.C.L. and Grainger, R.G.): Majorvascular complications in Behcet's syndrome 453
Herlinger, E.: Pancreatic and mesenteric arterio-graphy 755
Hetzel, B.S.: The aetiology and pathogenesis ofhyperthyroidism 363
Hinton, J.: Psychotropic drugs 286Hinton, J.M. (and J.E. Lennard-Jones): Con-
stipation: definition and classification 720Hoch, F.L.: Biochemistry of hyperthyroidism and
hypothyroidism 347Holden, C.E.A.: Congenital shortening of onefemur in one identical twin 813
Horn, M.E. (and Knapp, M.S.): Plasma 'ketone'level in the diagnosis of diabetic acidosis 799
Howat, H.T.: Chronic pancreatitis: medicalaspects 733
Howells, C.H.L. (and Everley Jones, H.): Neonatalmeningitis due to Streptococcus agalactiae 549
Hume Adams, J., (Linton, A.L. and Lawson, D.H.):Muscle necrosis and acute renal failure incarbon monoxide poisoning 338
Hunter, C.G. (and Kendrick, R.R.): Repeatedsamples of fat obtained with a biopsy needle 851
Hunton, M. (and Akinkugbe, 0.0.): Adultnephrotic syndrome in Ibadan, Nigeria: aprospective study of 135 cases 903
Jackson, W.P.U., (Bank, S., Keller, P. andMarks, I.N.): Serum-insulin response to glucosein 'pancreatic diabetes' 214
James, D.G. (and Sharma, O.P.): John McMichael'smultisystem interests 71
James, K.W., (Richardson, A.E., Spittle, C.R.and Robinson, O.P.W.): Experiences with car-benicillin in the treatment of septicaemia andmeningitis 844
James, W.B., (Groden, B.M. and McDicken, I.):Cardiac aneurysm after myocardial infarction 775
Jarrett, R.J. (and Keen, H.): The uses of biguanidesin diabetes mellitus 466
Jarrett, R.J., (Keen, H., Chlouverakis, C. andBoyns, D.R.): The effect of treatment of moder-ate hyperglycaemia on the incidence of arterialdisease 960
Jennings, R.C. (and Pengelly, C.D.R.): Endo-carditis parietalis fibroplastica (Loffler's disease) 251
Jindal, H.R.: Bilateral retrobulbar neuritis due toinsecticides 341
Joekes, A.M.: Acute tubular insufficiency 75Jones, N.L., (Fletcher, C.M. and Campbell,
E.J.M.): Research into bronchitis and em-physema 48
Kakkar, V.V. (and Tompkin, A.M.B.): Duodenalobstruction due to an anomalous portal vein 189
Postgraduate Medical Journal
Keen, H. (and Jarrett, R.J.): The uses of biguanidesin diabetes mellitus 466
Keen, H. (Jarrett, R. J., Chlouverakis, C. andBoyns, D. R.): The effect of treatment ofmoderate hyperglycaemia on the incidence ofarterial disease 960
Keller, P., (Bank, S., Jackson, W.P.U. and Marks,I.N.): Serum-insulin response to glucose in'pancreatic diabetes' 214
Kendrick, R.R. (and Hunter, C.G.): Repeatedsamples of fat obtained with a biopsy needle 851
Khan, A.: Cushing's syndrome associated withcarcinoma of pancreas 925
Khoo, T.C.L., (Enoch, B.A., Castillo-Olivares,J.L., Grainger, R.G. and Henry, L.): Majorvascular complications in Behqet's syndrome. 453
Kincaid-Smith, P.: Analgesic nephropathy andpapillary necrosis 807
Kingsbury, K.J.: Glucose tolerance, age andatherosclerosis 944
Knapp, M.S. (and Horn, M.E.): Plasma 'ketone'level in the diagnosis and treatment of diabeticacidosis 799
Kopelman, H.: The Epping Jaundice after twoyears 78
Krzaniak, S.: Ectopic gestation in a tubal stump 191
Lahiri, P.K. (and Sen, P.): Chemical mediators inthe central nervous system 167
Lal, H.B., (Bahl, A.L., Chugh, R.N., Mathur, K.P.and Bhalla, A.S.): Clinical patterns and com-plications of diabetes mellitus in India 223
Lal, H.B., (Bahl, A.L., Mukherjee, S., Dhawad,P.N., Sharma, A.K. and Sarin, G.S.): Un-usual presentation of intralobar pulmonarysequestration 479
Langman, M.J.S.: The medical treatment ofgastric and duodenal ulcer 603
Lawson, A.A.H. (and Steel, J.M.): Effects ofdifferent regimes of metyrapone on steroid pro-duction by a patient with a corticotrophinsecreting bronchogenic carcinoma 485
Lawson, D.H., (Linton, A.L. and Hume Adams,J.): Muscle necrosis and acute renal failure incarbon monoxide poisoning 338
Lennard-Jones, J.E.: Crohn's disease: naturalhistory and treatment 674
Lennard-Jones, J.E. (and Hinton, J.M.): Constipa-tion: definition and classification 720
Linton, A.L., (Hume Adams, J. and Lawson, D.H.):Muscle necrosis and acute renal failure in carbonmonoxide poisoning 338
Logan, W.F.W.E., (Fox, H. and Gleeson, M.H.):Intrahepatic granulomatous arteriopathy 256
Losowsky, M.S.: Investigation of portal hyper-tension 657
Lowe, K.G. (and Emslie-Smith, D.): The spatialvectorcardiogram in diagnosis 39
Lowenthal, M.N., (Doctor, S.A. and Fine, J.):Renal artery stenosis due to abdominal aorticaneurysm 928
Lowry, W.S.B.: A medical emergency treated byanti-mitotic drugs 926
McArthur, R.G. (and Moncrieff, M.W.): Hypo-thyroidism in one of monozygotic twins 423
McDicken, I., (Groden, B.M. and James, W.B.):Cardiac aneurysm after myocardial infarction 775
McGeown, M.G., (Soyannwo, M.O.A., Bell, M.and Milliken, T.G.): A case of acute hyperpara-thyroidism, with thyrotoxicosis and pancreatitis.presenting as hyperemesis gravidarum 861
McGirr, E.M. (and Thomson, H.A.): Hypothy-roidism due to enzyme defects 398
MacCarthy, J.M.T.: Bone sclerosis in infancy 908MacDonald, R.H. (and Proudfoot, A.T.): Infec-
tious-mononucleosis-like syndrome followinghaemodialysis for carbon tetrachloride poisoning 249
MacGuire, C.F., (Toghill, P.J. and Raut, P.S.):'Spontaneous' rupture of the healthy oesophagus 504
MacLellan, G.E. (and Chatterjee, K.): Sideropenicanaemia with reticulo-endothelial siderosis in acase of hypemephroma 259
MacLennan, W.J. (and Scott, R.): Intra-renalarterio-venous fistula with associated carcinomaof the kidney 867
Mahoney, J. (and Parkhouse, J.): A study of pre-operative sedatives 229
Mann, T.P.: Congenital malformations, A clinico-pathological conference held at the RoyalAlexandra Hospital for Sick Children. January1966 148
Marfatia, P.T.: Rhinolith. A brief review of theliterature and a case report 478
Marks, I.: Measurement of personality and atti-tude: applications to clinical research 277
Marks, I.N., (Bank, S., Jackson, W.P.U. andKeller, P.): Serum-insulin response to glucose inpancreatic diabetes 214
Marshall, J.: The differential diagnosis of LittleStrokes 543
Martin, A.: Hyperosmolar non-keto-acidotic dia-betic coma. A report of three cases and reviewof the literature 218
Mathur, K.P., (Lal, H.B., Bahl, A.L., Chugh,R.N. and Bhalla, A.S.): Clinical patterns andcomplications of diabetes mellitus in India 223
Mattingly, D. (and Cope, C.L.): Some recentadvances in adrenal diagnosis 23
Meadow, S.R.: Gastric teratoma 183Merskey, H.: Psychological aspects of pain 297Milliken, T.G., (Soyannwo, M.A.O., McGeown,M.G. and Bell, M.): A case of acute hyperpara-thyroidism with thyrotoxicosis and pancreatitis,presenting as hyperemesis gravidarum 861
Mills, J.: Anhidrotic ectodermal dysplasia pre-senting as a pyrexia of undetermined origin in theneonatal period 193
Misiewicz, J.J.: The application of motility studiesto gastroenterological problems 749
Mohammed, S.D. (and Chapman, R.S.): Pyrexiaand elevated erythrocyte sedimentation rate inacute gastro-duodenal haemorrhage 238
Moncrieff, M.W. (and McArthur, R.G.): Hypo-thyroidism in one of monozygotic twins 423
Monk, C.J.E., (Phillips, R.S. and Balmer, G.A.): Aplea for simplicity in the classification of anklefractures 199
XVi
Incdex to Voliume 44 xvii
Monti, G., (Scuro, L.A., Curri, G., Zuin, R. andRomani, S.): Arteriography o, the coeliac axisand superior mesenteric artery in five cases ofhaemochromatosis with particular regard to thepancreatic circulation 460
Morgan, D.B.: Osteomalacia and osteoporosis 621Mor-is, W.R.: Carotid endarterectomy in cerebral
vascular disease 242Morrison, N.D.W. (and Staffurth, J.S.): Heart size
in thyrotoxicosis 885Morson, B.C.: Ischaemic colitis 665Mounsey, P.: Praecordial pulsations in health and
disease 134Mounsey, P.: The value of praecordial pulsations
in the diagnosis of heart disease 8Mukherjee, S., (Lal, H.B., Bahl, A.L., Dhawad,
P.N., Sharma, A.K. and Sarin, G.S.): Unusualpresentation of intralobar pulmonary sequestra-tion 479
Myant, N.B.: The regulation of cholesterol meta-bolism 86
Neale, G.: Protein malnutrition in gastro-intestinaldisease 642
Nellen, M. (and Gotsman, M.S.): The systolicmurmur in hypertrophic obstructive cardio-myopathy and the nature of the obstruction 89
Newman, C.E.: John McMichael 35Nordin, B.E.C. (and Bulusu. L.): A modified index
of phosphate excretion 93Nuki, G. (and Bayliss, R.I.S.): The Achilles tendon
reflex as an index of thyroid function 97
Owen, J.V.: Synalbumin insulin antagonism 117
Papathanassiou, B.T., (Harto-Garofalidis, G.,Rigopoulos, C. and Papavassiliou, N.): A pre-and post-operative study of forty-six cases ofslipped intervertebral disc 144
Papavassiliou, N., (Harto-Garofalidis, G., Rigo-poulos, C. and Papathanassiou, B.): A pre- andpost-operative study of forty-six cases of slippedintervertebral disc 144
Parkhouse, J. (and Mahoney, J.): A study ofpre-operative sedatives 229
Parks, T.G.: Diverticular disease of the colon 680Parrott, R.H.: Granulosa-cell tumour of the ovary
causing sexual precocity in a girl aged 3! years 488Parry, T.E., (Surveyor, I., Evans, B. and Saunders,
K.C.): Autoimmune haemolytic anaemia com-plicating methyldopa therapy 438
Parsons, V. (and Ramsay, I.): Thyroid and adrenalrelationships 377
Pengelly, C.D.R. (and Jennings, R.C.): Endo-carditis parietalis fibroplastica (Loffler's disease) 251
Phillips, R.S., (Monk, C.J.E. and Balmer, G.A.):A plea for simplicity in the classification of anklefractures 199
Pollock, A.V.: Pancreatic disease: surgical aspects 737Post, F.: Psychological aspects of geriatrics 307Prankerd, T.A.J., (Broad, A.F., Emery, E.W. and
Godlee, J.N.): The management of myelomatosis 803Proudfoot, A.T. (and MacDonald, R.H.): Infec-
tious-mononucleosis-like syndrome followinghaemodialysis for carbon tetrachloride poisoning 248
Pulvertaft, C.N.: Comments on the incidence andnatural history of gastric and duodenal ulcer 597
Pulvertaft, C.N.: The late results of gastric surgery 613Pulvertaft, C.N.: Gastric resection and metabolic
bone disease 618Pyke, D.A. Coronary disease and diabetes 966
Ramsay, I. (and Parsons, V.): Thyroid and adrenalrelationships 377
Ramsay, I. Thyrotoxic muscle disease 385Raut, P.S., (Toghill, P.J. and MacGuire, C.F.):
'Spontaneous' rupture of the healthy oesophagus 504Read, A.E.: The pathogenesis and medical treat-
ment of hepatic encephalopathy 652Reimann, H.A.: Infectious diseases: annual
review of significant publications 517Reimann, H.A.: Nephropathy and viruses 853Richardson, A.E., (Spittle, C.R., James, K.W.and Robinson, O.P.W.): Experiences with car-benicillin in the treatment of septicaemia andmeningitis 844
Rigopoulos, C., (Harto-Garofalidis, G., Papavas-siliou, N. and Papathanassiou, B.T.): A pre- andpost-operative study of forty-six cases of slippedintervertebral disc 144
Robertson, W.B.: Diabetes, hypertension andatherosclerosis 939
Robinson, O.P.W., (Richardson, A.E., Spittle, C.R.and James, K.W.): Experiences with carbenicillinin the treatment of septicaemia and meningitis 844
Romani, S., (Scuro, L.A., Curri, G., Monti, G.and Zuin, R.): Arteriography of the coeliac axisand superior mesenteric artery in five cases ofhaemochromatosis with particular regard to thepancreatic circulation 460
Sabah, A.H.: Blindness after cardiac arrest 513Sarin, G.S., (Lal, H.B., Bahl, A.L., Mukherjee, S.,Dhawad, P.N. and Sharma, A.K.): Unusualpresentation of intralobar pulmonary sequestra-tion 479
Saunders, K.C., (Surveyor, I., Evans, B. andParry, T.E.): Autoimmune haemolytic anaemiacomplicating methyldopa therapy 438
Saunders, S.J.: Recent trends in acute viral hepatitis 97Scadding, J.G.: A 'burnt-out' case of sarcoidosis 105Schraibman, 1.G.: Gas gangrene after amputation
for peripheral vascular disease 551Schwartz, S.: A simplification of the knee-jointmeniscectomy operation 212
Scott, D.F.: Psychiatric aspects of epilepsy 319Scott, G.A.: Observations on Melkersson's syn-drome 447
Scott, R. (and MacLennan, W.J.): Intra-renalarterio-venous fistula with arsociated carcinomaof the kidney 867
Scuro, L.A., (Curri, G., Monti, G., Zuin, R. andRomani, S.): Arteriography of the coeliac axisand superior mesenteric artery in five cases ofhaemochromatosis with particular regard to thepancreatic circulation 460
Sen, P. (and Lahiri P.K.): Chemical mediators inthe central nervous system 167
xviii Postgraduate Medical Jolurnal
Shaw, A.B. (and Woolcock, J.A.): Oliguricglomerulonephritis and parathyroid adenoma 246
Sharma, A.K., (Lal, H.B., Bahl, A.L., Mukherjee,S., Dhawad, P.N. and Sarin, G.S.): Unusualpresentation of intralobar pulmonary sequestra-tion 479
Shephard, R.H., (Walker, M.E. and Espir, M.):Subdural haematoma: presentation and diagnosison medical wards 785
Sherlock, S.: Hepato-lineal fibrosis without cir-rhosis: non-cirrhotic intrahepatic portal hyper-tension 109
Sircus. W.: Peptide-secreting adenomata withspecial reference to the Zollinger-Ellison syn-drome 742
Smith, D. Emslie (and Lowe, K.G.): The spatialvectorcardiogram in diagnosis 39
Smith, P. Kincaid- (and Fairley, K.F.): Renaldisease in pregnancy 45
Somerville, J., (Conway. N. and Beck, E.):Penicillin encephalopathy 891
Soyannwo, M.A.O., (McGeown, M.G., Bell, NI.and Milliken, T.G.): A case of acute hyper-parathyroidism, with thyrotoxicosis and pan-creatitis, presenting as hyperemesis gravidarum 861
Spittle, C.R., (Richardson, A.E., James, K.W.and Robinson, O.P.W.): Experiences withcarbenicillin in the treatment of septicaemia andmeningitis 844
Staffurth, J.S. (and Morrison, N.D.W.): Heart sizein thyrotoxicosis 885
Steel, J.M. (and Lawson, A.A.H.): Effect ofdifferent regimes of metyrapone on steroid pro-duction by a patient with a corticotrophinsecreting bronchogenic carcinoma 495
Stewart, J.S.: Adult coeliac disease 632Surveyor, I., (Evans, B., Saunders, K.C. and
Parry, T.E.): Autoimmune haemolytic anaemiacomplicating methyldopa therapy 438
Talbot, J.F. (and Barcroft, H.): Oliver andSchaffer's discovery of the cardiovascular actionof suprarenal extract 6
Taraba, I. (and Bull, G.M.): Failure of folic acid toinfluence mortality of rats with acute tubularnecrosis caused by mercury 116
Tattersfield, A.E.: Tricuspid incompetence due toright ventricular papillary muscle dysfunction 254
Taylor, J.J. (and Evans, D.W.): Lymphosarcomaduring the course of myeloid leukaemia 558
Taylor, S.: Thyroid carcinoma and its treatment 404Tennant, R. (and Handa, S.P.): Medullary cystic
disease of the kidney: its occurrence in twosiblings 792
Tewari, S.N. (and Grant, R.H.E.): Propranolol inhypertension 509
Thompson, G.R.: Studies in the absorption andmetabolism of vitamin D after gastric surgery 626
Thomson, J.A. (and McGirr, E.M.): Hypothyroid-ism due to enzyme defects 398
Toghill, P.J., (MacGuire, C.F. and Raut, P.S.):'Spontaneous' rupture of the healthy oesophagus 504
Toghill, P.J. (and Williams, R.): The wideningspectrum of neurological damage in liver disease 173
Tomlinson, B.E. (and Cullen, D.R.): Carcinomawith multiple ectopic hormone secretion andassociated myopathy 472
Tompkin, A.M.B. (and Kakkar, V.V.): Duodenalobstruction due to an anomalous portal vein 189
Trapnell, J.E.: The pathogenesis of gallstonepancreatitis 497
Turner, R.C. (and Bloom, A.): Diabetes mellitus,Addison's disease and pernicious anaemia 555
Walker, M.E., (Espir, M. and Shephard, R.H.):Subdural haematoma: presentation and diag-nosis on medical wards 785
Wardle, E.N.: Purpura hyperglobulinaemia inassociation with rheumatoid and ulcerativecolitis 443
Watkinson, G.: The systemic complications ofulcerative colitis 693
Watkinson, G.: The medical treatment of ulcera-tive colitis 696
Weir, D.G.: Recovery of villous architecture ingluten enteropathy exacerbated by gastro-jejunalanastomosis 234
Weir, R.J. (and Buchanan, J.): Effect of direct-current countershock on atrial flutter withcomplete heart block in a case of staphylococcalsepticaemia 811
West, J.B.: Regional differences in the lung 120Whitelaw, J., (Groden, B.M. and Will, G.): The
treatment of iron-deficiency anaemia by iron-dextran infusion, with special reference to theeffect on blood-grouping, coagulation, sedimen-tation and haemolysis 433
Wilkins, E.G.: Constipation in the elderly 728Will, G., (Groden, B.M. and Whitelaw, J.): The
treatment of iron-deficiency anaemia by iron-dextran infusion, with special reference to theeffect on blood-grouping, coagulation, sedimen-tation and haemolysis 433
Williams, D.M. (and Enoch, B.A.): An associationbetween Wernicke's encephalopathy and thyro-toxicosis 923
Williams, R. (and Toghill, P.J.): The wideningspectrum of neurological damage in liver disease 173
Woolcock, J.S. (and Shaw, A.B.): Oliguric glo-merulonephritis and parathyroid adenoma 246
Wright, A.D. (and Fraser, R.): Standard proceduresfor assessing hypersecretion or secretor capacityfor human growth hormone using the radio-immunoassay 53
Wright, R.: Autoimmune d;sease of the gastro-intestinal tract 765
Zuin, R. (Scuro, L.A., Curri, G., Monti, G. andRomani, S.): Arteriography of the coeliac axisand superior mesenteric artery in five cases ofhaemochromatosis with particular regard to thepancreatic circullation 460
Postgraduate Medical Journal: Notice to Contributors
Typescripts (two complete copies) should be sent tothe Editor, Dr A. A. G. Lewis, Postgraduate MedicalJournal, 9 Great James Street, London, W.C.I.Papers should be typewritten on one side of thepaper only, with a 1j inch margin, and the linesshould be double-spaced. In addition to the title ofthe paper there should be a 'running title' (for pageheadings) of not more than 45 letters (includingspaces). The paper should bear the name of theauthor(s) with their degrees and descriptions and ofthe laboratory or research institute where the workhas been carried out. The full postal address of theprincipal author should be given as a footnote. (Theproofs will be sent to this author and address unlessotherwise indicated).Armngement. Papers should normally be dividedinto: (a) Introduction; (b) Materials and methods;(c) Results, as concise as possible (both tables andfigures illustrating the same data will rarely bepermitted); (d) Discussion and conclusions; (e)Summary, brief, self-contained and embodying themain conclusions; (f) Acknowledgments; (g)References.
References. Only papers closely related to theauthor's work should be included, exhaustive listsshould be avoided. References should be made bygiving the author's surname, with the year of publi-cation in parentheses. When reference is made to awork by three authors all names should be givenwhen cited for the first time, and thereafter only thefirst name, adding et al., e.g. Smith et al. (1958).The 'et al!' form should always be used for works byfour or more authors. If several papers by the sameauthor and from the same year are cited, a, b, c, etc.,should be put after the year of publication, e.g.Smith et al. (1958a). All references should be broughttogether at the end of the paper in alphabetical order.References to articles and papers should mention(a) name(s) of the author(s); (b) year of publicationin parentheses; (c) title of paper; (d) title of journal,underlined, abbreviated according to World MedicalPeriodicals (3rd edn, World Medical Association);(e) volume number; number of first page of article.References to books and monographs should include(a) name(s) and initials of author(s) or editor(s);year of publication in parentheses; (b) title, under-lined; (c) edition: (d) page referred to; (e) publisher;(f) place.Standard usage. The Concise Oxford English Diction-ary is used as a reference for all spelling and hyphen-ation. Verbs which contain the suffix ize (ise) andtheir derivatives should be spelt with the z. Statisticsand measurements should always be given in figures,i.e. 10 min, 20 hr, 5 ml, except where the numberbegins the sentence. When the number does not
refer to a unit of measurement, it is spelt out exceptwhere the number is greater than one hundred.Abbreviations. Abbreviations for some of thecommoner units are given below. The abbreviationfor the plural of a unit is the same as that for thesingular unless confusion is likely to arise.
gram(s) g second(s) seckilogram(s) kg cubic millimetre(s) mm3milligram(s) millimetre(s) mm
(10-3 g) mg centimetre(s) cmmicrogram(s) millicurie(s) mCi
(10-6 g) u.g millilitre(s) mlnanogram(s) pound(s) lb
(10-9 g) ng milliequivalent mEqpicogram(s)
(10- 12 g)hour(s)minute(s)micron(s)
pghrmin
RF values RF
gravitational acceleration gper cent %
Example: mg/100 ml, for biochemical values; mEq/l
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