PORTUGAL REPORT ON THE PREVENTIVE VACCINATION PLAN … · DSPA/ Direção Geral de Alimentação e...
Transcript of PORTUGAL REPORT ON THE PREVENTIVE VACCINATION PLAN … · DSPA/ Direção Geral de Alimentação e...
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PORTUGAL REPORT
ON THE PREVENTIVE VACCINATION PLAN FOR AVIAN
INFLUENZA IN A GAME BIRD HOLDING OF BREEDING
DUCKS (Anas Platyrhynchus)
Commission Decision 2012/110/UE
SCoFCAH Brussels, 10&11 September 2013
DSPA/ Direção Geral de Alimentação e Veterinária
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History
• Emergency Vaccination Plan (EVP), approved by Decision
2008/285/EC → applied until 31 July 2008
• Preventive Vaccination Plan for 2008/2009 (PVP1), approved
by Decision 2008/838/EC → applied until 31 July 2009
• Preventive Vaccination Plan for 2010/2011 (PVP2), approved
by Decision 2010/189/EU → applied until 31 July 2011
• Preventive Vaccination Plan for 2012/2013 (PVP3), approved by Decision 2012/110/UE
→ applied until 31 July 2013
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Vaccination Plan (PVP3)
• Monovalent vaccine (subtype H5)
• 50 non-vaccinated ducks (sentinels)
• Subcutaneous administration (0,5-1ml)
• Individual identification of vaccinated ducks (wing tags)
• Surveillance and monitoring of the vaccinated flocks
• Surveillance of unvaccinated poultry flocks in the surrounding area
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Vaccination procedures
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Vaccination Plan (PVP3)
Plan Date Vaccine Flock 4 Flock 5
PVP2 V7 02-12-2010 H5N3 1st application
PVP2 V8 17-12-2010 H5N3 2nd application
PVP3 V9 10-03-2011 H5N2 Revaccination
PVP3 V10 28-12-2011 H5N2 Revaccination
PVP3 V11 13-12-2012 H5N2 1st application
PVP3 V12 10-01-2013 H5N2 2nd application
PVP3 V13 07-06-2013 H5N2 Revaccination
Flock 4 Flock 5
Males 878 700
Females 3.508 2.800
Total 4.386 3.500
Age at 1st application 7 months 8 months
Slaughter date July 2012 July 2014
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Serological Monitoring of vaccine response (PVP3)
• 20 blood samples from vaccinated ducks every month
• Antibodies titre by HI
• Positivity: titre 1:16
• All samples sent to the National Reference Laboratory
Flock 4 Flock 5
Min. <1:16 - 1:32 <1:16 - 1:256
Max. 1:32 - 1:512 1:64 - 1:1024
Mode 1:16 - 1:128 <1:16 - 1:1024
Median 1:16 - 1:64 1:16 - 1:1024
Geo.Mean 1:16 - 1:64 1:16 - 1:1024
%Positivity 70% - 100% 50% - 100%
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Serological Monitoring of vaccine response (PVP3)
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Serological Monitoring of vaccine response (PVP3)
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15 monthly reports (behavioural and clinical surveillance)
sent by the veterinarian to the Official Services
Clinical surveillance (PVP3)
Flock Period Mortality Food
Intake Water Intake
Growth
4 Dec. 2011. to June 2012
Normal (< 0,1%) Normal Normal Normal
5 Dec. 2012 to July 2013
Normal (< 0,1%) Normal Normal Normal
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Surveillance results (PVP3)
Samples Flock 4 Flock 5
Sentinels 180 180
Dead ducks 6 9
Poultry flocks in the surrounding area
35 70
Total 221 259
All results were negative
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THANK YOU FOR YOUR ATTENTION