PORTUGAL INFORMATION ON PAST AND NEW VACCINATION … · BREEDING MALLARD DUCKS (Anas platyrhynchus)...
Transcript of PORTUGAL INFORMATION ON PAST AND NEW VACCINATION … · BREEDING MALLARD DUCKS (Anas platyrhynchus)...
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PORTUGAL
INFORMATION ON PAST AND NEW
VACCINATION PLAN FOR AVIAN INFLUENZA IN
A GAME BIRD HOLDING OF
BREEDING MALLARD DUCKS (Anas platyrhynchus)
Direção Geral
de Alimentaçãoe Veterinária
www.dgav.pt
Brussels, 5 March 2015
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History Direção Geral
de Alimentaçãoe Veterinária
Outbreak of LPAI subtype H5 → September 2007
Emergency Vaccination Plan (EVP), approved by Decision 2008/285/EC
→ applied until 31 July 2008
Preventive Vaccination Plan for 2008/2009 (PVP1), approved by Decision
2008/838/EC → applied until 31 July 2009
Preventive Vaccination Plan for 2010/2011 (PVP2), approved by Decision
2010/189/EU → applied until 31 July 2011
Preventive Vaccination Plan for 2012/2013 (PVP3), approved by Decision
2012/110/EU → applied until 31 July 2013
Preventive Vaccination Plan for 2013/2014 (PVP4), approved by
Decision 2013/651/EU → applied until 31 December 2014
Preventive Vaccination Plan for 2015/2016 (PVP5), submitted
→ until 31 July 2018
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Criteria justifying a preventive vaccination
Direção Geral
de Alimentaçãoe Veterinária
• Vaccine is a valuable tool for the reduction
of susceptibility to infection, virus shedding
and spreading
• Holding is located in a high risk area for AI
• Increased risk of becoming infected with AI
viruses for this type of holding
• Good results from the previous vaccination
plans
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Vaccination Plan
Direção Geral
de Alimentaçãoe Veterinária
• Monovalent vaccine (subtype H5)
• Subcutaneous administration (0,5 ml)
• Individual identification of vaccinated ducks (wing tags)
• 50 non-vaccinated ducks (sentinels)
• Surveillance and monitoring of the vaccinated flock
• (Surveillance of poultry flocks in the surrounding area,
within the framework of the AI surveillance plan)
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Wing tags
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Sentinels
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Vaccination procedures Direção Geral
de Alimentaçãoe Veterinária
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Surveillance and monitoring of vaccinated flock
Direção Geral
de Alimentaçãoe Veterinária
• Behavioral (water and food consumption)
• Clinical
• Serological monitoring of vaccinated birds
• Surveillance: virological evaluation (sentinels,
diseased or dead birds)
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Direção Geral
de Alimentaçãoe Veterinária
• Serological monitoring of vaccine response
– 20 blood samples from vaccinated ducks every month
– Antibodies titer by HI
– Positivity: titer 1:16
– All samples sent to the National Reference Laboratory
• Behavioural and clinical surveillance
– Monthly reports sent by the veterinarian to the Official Services
• Surveillance: virological evaluation
– 15 cloacal swabs + 15 oropharyngeal swabs per month
– PCR and virus isolation if PCR is positive
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Direção Geral
de Alimentaçãoe Veterinária
Report on the Vaccination Plan
2013-2014 (PVP4)
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Direção Geral
de Alimentaçãoe Veterinária
Plan Date Vaccine Flock 5 Flock 6
PVP3 V11 13-12-2012 H5N2 1st application
PVP3 V12 10-01-2013 H5N2 2nd application
PVP3 V13 07-06-2013 H5N2 Revaccination
PVP4 V14 09.01.2014 H5N2 Revaccination
PVP4 V15 06.11.2014 H5N2 1st application
PVP4 V16 04.12.2014 H5N2 2nd application
Flock 5 Flock 6
Males 700 1000
Females 2800 3450
Total 3500 4450
Age at 1st application 8 months 8 months
Slaughter date August 2014 2nd semester 2016
Flocks 5 and 6
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Clinical and behavioral surveillance
Direção Geral
de Alimentaçãoe Veterinária
Flock Mortality Feed
intake
Water
intake Growth
5 Normal (< 0,1%) Normal Normal Normal
6 Normal (< 0,1%) Normal Normal Normal
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Serological monitoring of vaccine response
Direção Geral
de Alimentaçãoe Veterinária
Flock 5 Flock 6
Min. 1:16 - 1:1024 1:8 - 1:32
Max. 1:128 - 1:2048 1:64 - 1:512
Mode 1:128 - 1:1024 1:8 - 1:128
Median 1:128 - 1:1024 1:16 - 1:128
Geo.Mean 1:64 - 1:1024 1:16 - 1:128
%Positivity 100% 60% - 100%
July 2013 - Aug 2014 Dec 2014 – Jan 2015
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Serological monitoring of vaccine response
Direção Geral
de Alimentaçãoe Veterinária
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Serological monitoring of vaccine response
Direção Geral
de Alimentaçãoe Veterinária
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Surveillance results
Direção Geral
de Alimentaçãoe Veterinária
All results were negative
Samples Flock 5 Flock 6
Sentinels 360 60
Dead ducks 0 3
Poultry flocks in the
surrounding area 140
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Direção Geral
de Alimentaçãoe Veterinária
Vaccination Plan for
2015-2018 (PVP5)
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Direção Geral
de Alimentaçãoe Veterinária
Vaccination Plan
Plan Provisional Date Flock 6
PVP5 May 2015 Revaccination
PVP5 November 2015 Revaccination
PVP5 May 2016 Revaccination
Flock 6
Males ± 1.000
Females ± 3.550
Total ± 4.450
Continue vaccination of subsequent breeding flocks up to July 2018
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Direção Geral
de Alimentaçãoe Veterinária
Movement restrictions
• Vaccinated mallard ducks will not be moved to other
poultry holdings within the country or dispatched to other
Member States
• After their reproductive period, the vaccinated ducks will be
killed humanely on the holding and their carcases safely
disposed off
• The descendants that leave the holding will be, at least, 4
months old and only for restocking of wild game supplies
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THANK YOU FOR YOUR ATTENTION
Direção Geral
de Alimentaçãoe Veterinária
www.dgav.pt