Plegable Biomol Mateo Torres
-
Upload
mateo-torres -
Category
Health & Medicine
-
view
25 -
download
0
Transcript of Plegable Biomol Mateo Torres
![Page 1: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/1.jpg)
Transcription,gene regulation and operons
Mateo Torres Ceballos Medicine Student
![Page 2: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/2.jpg)
![Page 3: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/3.jpg)
![Page 4: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/4.jpg)
IntroductionTranscr ipt ion is an i m p o r t a n t p ro c e s s during the expression of the DNA
Some studies try to create a vaccine to prevent from virus for example from coxsackievirus
![Page 5: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/5.jpg)
Long noncoding RNA found to quell inflammation University of Massachusetts Medical School (2016, July 14).
![Page 6: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/6.jpg)
Long noncoding RNA found to quell inflammation
A long noncoding RNA is responsible for regulating the innate immunity and i s v e r y c a r e f u l l y regulated
Found in
Microphages
![Page 7: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/7.jpg)
Long noncoding RNA found to quell inflammation
Researches study this RNA using a mouse model lacking of lincRNA-EPS
![Page 8: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/8.jpg)
Long noncoding RNA found to quell inflammation
This RNA can provide information about Lupus and inflammatory bowel disease
![Page 9: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/9.jpg)
Long noncoding RNA found to
quell inflammation
Student`s observation
I think this discovery is important because it can led to the understanding of a several pathologies related with the immune system and inflammatory processes, providing the best way to treat them so they won`t be more a difficulty like nowadays
![Page 10: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/10.jpg)
Biochemists feed “poison pill” to deadly virus
Colorado State University (2016, July 15).
![Page 11: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/11.jpg)
Biochemists feed “poison pill” to deadly virus
The RNA polymerase is the enzyme implicated in making the copies of the virus
![Page 12: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/12.jpg)
Biochemists feed “poison pill” to deadly virus
Researchers are creating a vaccine with change of an aminoacid in the RNA polymerase (phe tyr) to minimize the chances of an infection produced by the vaccine
The enzyme will make l o w e r m u t a t i o n s , reducing the capacity of the virus to replicate and cause illness that will cause a self-destruction
“Genetic poison pill”
![Page 13: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/13.jpg)
Biochemists feed “poison pill” to deadly virus
This poison pill could also be effective with those RNA viruses linked with asthma a n d f o o t - a n d - m o u t h disease
![Page 14: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/14.jpg)
Biochemists feed “poison pill” to deadly virus
Student`s observation
I think this investigation is important because it can provide a mechanism of protection to certain viruses that produce deseases that in some cases can be lethal
![Page 15: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/15.jpg)
Medical Utility
![Page 16: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/16.jpg)
Medical Utility
Both researches are trying to find the way to prevent diseases cause either by a type of RNA or for viruses
![Page 17: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/17.jpg)
Medical Utility
Even though the investigations are looking for something specific, they can also give a lot of information about other diseases that can be illustrated with further investigations about it
![Page 18: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/18.jpg)
Medical Utility
Through the understanding of the process behind the inflammatory diseases caused by uncontrolled immune responses like lupus the researchers can find a better way to treat it
![Page 19: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/19.jpg)
Bibliography• Colorado State University. (2016, July 15). Biochemists
feed 'poison pill' to deadly virus. ScienceDaily. R e t r i e v e d S e p t e m b e r 1 , 2 0 1 6 f r o m w w w . s c i e n c e d a i l y . c o m / r e l e a s e s /2016/07/160715130201.htm
• University of Massachusetts Medical School. (2016, July 14). Long noncoding RNA found to quell inflammation: Researchers implicate lincRNA in immune system. ScienceDaily. Retrieved September 1, 2016 f rom www.sc ienceda i ly.com/re leases/2016/07/160714120654.htm
• Martinez Sánchez, Lina Maria. Biologia Molecular. 2. ed. Medellin: UPB. Fac. de Medicina, 2006. 208 p.
![Page 20: Plegable Biomol Mateo Torres](https://reader033.fdocuments.us/reader033/viewer/2022042907/58d070181a28abc9788b4de1/html5/thumbnails/20.jpg)
“The distance between your dreams and reality is called action”