Innovative InvestmentsAdvancing Healthcare

Annual Arab Health Dinner

2015

Annual Dinner 2015

Regional Life Sciences

Platform Update

KLSC is fully owned by NTEC, the technology transfer arm of the Kuwait Investment Authority

World’s First Sovereign Wealth Fund Established in 1953 >550 bn USD in AUM

Created by Kuwait’s Council of Ministers Established in 2005 Fully owned by the KIA 100 mn KD or ~ $350 mn paid up capital Five fully owned subsidiary companies:

Clean and Alternative Energy

Investments

Life Sciences and Healthcare

Investments

ICT and Mobile Technology Investments

Strategic and Technology

Advisory Services

Human Capital Development Solutions

and HR Services

From 2006 to 2009, prior to KLSC establishment, NTEC Life Sciences team developed its relationships and cemented its strategy

The KLSC team studied and analyzed the Life Sciences Sector in MENA…

…and developed a strategy to develop unique platforms that would catalyze technology transfer to the region

The NTEC Life Sciences team developed strong relationshipswith leading International

Industry Pioneers and Investors

Technology InvestorsTechnology Pioneers

Knowledge Transfer Platform

PharmaceuticalCommercialization

Platform

Medical DevicesCommercialization

Platform

Industrial(Specialty Chemicals)

Platform

Clinical Research (CRO)

Platform

Starting in 2010, operational strategy started implementation

Building on the aforementioned strategy, KLSC developed five individual platform companies to stimulate the life sciences sector in MENA

Operational in 2010 Fully owned by the NTEC 15 mn KD or ~ $53 mn paid up capital Five platform companies in life sciences:

MENA’s leadingContract Resource

Organization

Medical Devices and Consumables Distribution

MENA’s FirstLife Science Focused

Training Academy

MENA’s PremiereActive Pharmaceutical Ingredients Producer

Leading PharmaceuticalLicensor for the Middle

East and Africa

World Class Partners:

The Why? NewBridge aims to improve the access for ‘big pharma’ companies, genomics and biologicsmanufacturers to the MENA region

The How?NewBridge pharmaceuticals is a regional specialty company providing one-stop-solution to pharmaceuticals, biological, genomics and other innovative healthcare companies

The What? NewBridge is the exclusive licensor of pharmaceutical products in:

Oncology Immunology NutritionAstral®, Aware®, Clasteon™, Halaven® Cimzia® Celia®, Delicel®, M2PK®, Oncotype Dx®, Sancuso® RealDiet™, Taranis®

CNS Care Dermatology Metabolic Care Woman’s HealthNeupro®, Vimpat® Ebenet® Diabase® Glinconorm®, Pylera® Femmed®,Verifi®

Joe Henein, President and CEO Former VP & Managing Director ME/Africa - Wyeth Former VP & Therapeutic Area Head – Women Heath Former VP & Global Therapeutic Commercial Chair -

Wyeth

A leading MENA pharmaceutical licensor

Anchored in 2011 Venture Capital

Regional Footprint

The Why? Innomedics aims to improve the efficiency of the healthcare system and encourage value based medicine by providing the most efficient and best value medical equipment and consumables

The How?Innomedics delivers innovative personalized health and mobile health products directly to the consumers via partnerships with local pharmacy and retail distributors

The What? Innomedics is a regional distributor of medical equipment in the GCC region that provides innovative medical products and consumables to both government and private sector healthcare service providers

Dr. Zahran Ahmed, Sales Director Total 20 years experience in medical devices distribution Director of Medical &Scientific Division, Al -Hajery & Sons Sales supervisor Bristol-myers SquibbA leading GCC focused medical devices

and consumables distribution company

Incubated in 2011 Venture Capital

Innovative Medical Products

World Class Partners and Agencies:

The Why? Clinart hopes to improve the ability for big pharma companies and governments to host world-class clinical trials in the MENA region

The How?Clinart provides quality services with a proven track record of successful trials in the region (phase II-IV) since 2001

The What? Clinart MENA is a Full Service Contract Research Organization (CRO) headquartered in Dubai Health Care City, that brings Clinical Research expertise to the Middle East region in line with local cultures and customs

Dr. Alaa Assem, President and CEO 20 years experience in MENA with Sandoz, Lilly, Wyeth,

Pfizer M.Sc in Ophthalmology from University of Alexandria MBA from Maastricht School of Management

(Netherlands)

Invested in 2012 Growth Capital

Experience by Therapeutic Area

World Class Partners and Clients:

Over 8,000 Patient’s Recruited for Non-Interventional Studies

A leading MENA focused CRO

The Why? LSA aims to develop healthcare professionals knowledge, practice, and clinical outcome LSA believes in transforming healthcare leaders to advance the system & inspire change

The How?LSA has prestigious affiliations with international top ranked medical universities to provide state-of-the-art training programs which are accredited and recognized for its value & impactLSA also collaborates with regional & local experts to share latest practices in their field

The What? Unique platform for Continuous Professional Development (CPD) programs, Continuous Medical Education (CME), and Evidence-based Professional Development (EPD)

In 2014, LSA has offered +70 various training programs to +700 participantsIn 2015, LSA plans to conduct 85 programs and opens its training facility in March 2015

First Healthcare Training App in GCC

Ph. Mohammad Nahis Al Anzi, CEO Former COO at Kuwait Life Sciences Company MBA, Maastricht School of Management, B.Sc, Pharmacy, University of Sunderland Certified Professional Coach, ICF

The First Healthcare Academy in the GCC

Incubated in 2013 Venture Capital

World Class Partners:

The Why? eCore aims to improve access for pharmaceutical manufacturers to best in class APIs at a reasonable value proposition

The How?eCore is focused on commercial and representation services in the field of industrial chemicals for the Middle East and Africa region, across multiple industries including Food, Feed, Pharmaceuticals, Paints, and home care

The What? eCore is involved in: Representation services - for reputable suppliers to develop their business in the MENA marketImportation and Distribution servicesExportation services - to support local MENA companies in identifying new export opportunities for their products

Eng. Wael Gaama, CEO 30 years of experience in API industry with Ciba-Geigy,

Rhone, Poulenc/Rhodia MBA, Ecole des HEC - Universite de Lausanne BS, Faculty of Engineering - University of AlexandriaMENA’s Premiere Manufacturer of

Active Pharmaceutical Ingredients (APIs)

Added in 2014 Growth Capital + Exit for Existing Partner

A Diversified Echelon of Clients Across Multiple Industries:

Regional Footprint

KLSC is also an investor in multiple healthcare and life science funds and companies across the world

Investment Location Description

“KLSC invests between 3 to 5 mn USD for Significant Minority Shares in Revenue generating companies that are ideally looking for a commercial partner for MENA”

LP in Burrill Life Sciences Capital Fund III 300 mn USD fund focused on life sciences Investments include: Acusphere, Ceptanis, Gevo, Taiwan Liposome,

Neos Therapeutics, Nevotech, Nova Therapeutics, OcooGenex, NovadaqTechnologies, Vividia, Waterstone Pharmaceuticals, Wellpartner Inc.

LP in WP Venture IV Life Science Fund 100 mn USD fund focused on life sciences Investments include: Genticel, Middle Peak, Immatics, Neuway Pharma,

Rigontec, Definiens, ImevaX

San Francisco, USA

Germany

Birmingham, UK

Ind

ire

ct (

Fun

ds)

Dir

ect

Aix-en-Provence, France

Quanta is focused on the development and commercialisation of a novel cartridge-based haemodialysis system named SC+

SC+ is the only high performance, portable, compact haemodialysis system with the clinical efficacy and high flow rates of traditional in-centre machines

The only ultrasound system with an UltraFast™ platform This SuperSonic speed enables innovations such as ShearWave™

Elastography and UltraFast™ Doppler while rendering clinically detailed B-mode image quality for all clinical applications

Valbonne, France Provides advanced medical imaging products and services for diagnosing and monitoring cancer patients in both routine clinical practice and clinical drug development

Innovative InvestmentsAdvancing Healthcare

THANK YOU

KIPCO Tower, 27th Floor, Al Shuhadaa St., SharqP.O. Box 25363, Safat 13114, Kuwait

Tel : +965 22215622Fax: +965 2249 0959

www.klsc.com.kw

Thank you and Enjoy the Dinner