Physiology of Energy Expenditure Eric Ravussin [email protected]
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Physiology of Energy Expenditure Eric Ravussin [email protected]. DRUGS?. ENVIRONMENT. ACTIVITY?. Physical Environment. Energy Partitioning Fat Accretion. Obesity. Behaviors. Social Environment. Overweight. Adipogenesis. Biology. Energy Intake. Energy Expenditure. - PowerPoint PPT Presentation
Transcript of Physiology of Energy Expenditure Eric Ravussin [email protected]
Diapositiva 1
Physiology of Energy Expenditure
Eric [email protected]
DRUGS?ACTIVITY?ENVIRONMENT
BiologySocial EnvironmentBehaviorsPhysical EnvironmentObesityAdipogenesisOverweightEnergy Partitioning FatAccretionEnergy Intake Energy ExpenditureBouchard and Rankinen, 2007SS 08 0908 HUEC8/17/2012 8:08 AM3SS 07 0827 Taiwan (from Toronto and Oulu)8/17/2012 8:08 AM3V2004 0516 01 obesityChanged 10/17/07 Last used 9/08/08, 7/08/08, 11/14/07, 10/24/07, 9/28/07, 8/27/07, 6/25/07, 6/7/07, 3/30/07, 6/15/06, 1/20/06, 1/19/06, 9/21/05, 6/20/05, 6/11/05, 5/30/05, 5/18/05, 4/14/05, 2/25/05, 2/17/05, 1/17/05Causes series obesogenic diagramClement, Ch 11Obesogenic EnvironmentObesogenic BehaviorBiologyObesityAdipogenesisOverweightEnergy ExpenditureEnergy Partitioning FatAccretionEnergy Intake Social EnvironmentBuilt EnvironmentSS 08 0908 HUEC8/17/2012 8:08 AM4SS 07 0827 Taiwan (from Toronto and Oulu)8/17/2012 8:08 AM4V2004 0516 20.1 -cs obesity Changed 9/23/07 Last used 9/08/08, 7/08/08, 2/13/08, 11/14/07, 10/24/07, 8/27/07, 6/25/07, 3/30.1/07, 9/01/06, 6/15/06Causes series obesogenic diagram
Traditional EnvironmentLeptogenic EnvironmentSocial EnvironmentBuilt EnvironmentObesogenic Environment1900s2000sLeptogenic environmentObesogenicenvironmentBMI (kg/m )2GeneticsEnvironmentGeneticsObesity ResistantObesity ProneObesity SusceptibilityObesity SusceptibilityRedman & Ravussin 2008
SS 05 1108 Dallas AM 8/17/2012 8:08 AM6
Walk the dog and keep fitThe American waySS 05 1108 Dallas AM 8/17/2012 8:08 AM7
NHANES 1976-1980NHANES 1999-20041976-198032.1 0.615.0 0.41.4 0.12003-200433.4 1.232.9 1.35.1 0.6BMI distribution (%)OverweightObeseExtremely ObeseRedman & Ravussin 2008Putative Contributors to the Secular Increase inObesity Besides more Food and less ActivityKeith SW et al. Int J Obes. 2006;30:1585-1594; and McAlister et al., Crit Rev in Food Sci & Nutr, 2009.12131415161718192021222324252627282930313278910111213141516171819202122232425636465666768697071727374757677787980555657585960616263646566676869707172737475767778798054.55555.55656.55757.558.559.5596060.56161.56262.56363.56464.56565.56666.567.558672121.2521.521.752222.2522.522.752323.2523.523.752424.2524.524.752525.2525.525.752602505007501000122515001750200022502500275030003250350037504000.34.35.36.37.38.39.40.41.42.43.44.45.46.47.48.49.5015.515.615.715.815.91616.116.216.316.416.516.616.716.816.91717.117.217.3Prevalence of AC (%)Nonsmoker prevalence (%)Antidepressant prescriptions (millions)Adult obesity prevalence (%)Time spent awake (hours/day)Proportion Hispanic and/or aged between 35 and 55 yearsPBDE concentration (pg/g)Mean age of mothers at first birth (years)Average home temperature (F)196019651970197519801985199019952000YearAdult obesity prevalence (%)Antidepressant prescriptions(millions)Average home temperature (F)Mean age of mothers at firstbirth (years)Nonsmoker prevalence (%)PBDE concentration (pg/g)Prevalence of AC (%)Proportion of Hispanicand/or aged between35 and 55 yearsTime spent awake(hours/day)91 % e r r o r = 1 kg / yrLong-term Weight Homeostasis Principles of Energy Balance
Energy Stores> 60,000 kcalCarbohydrate2,000 kcalProtein40,000 kcalFat125,000 kcal1,00050-100%5001.3%1,000
