Pharmointro
description
Transcript of Pharmointro
PHARMACOLOGYPHARMACOLOGYScience dealing with
interactions between living systems and molecules,
especially chemicals from outside the body.
Science dealing with interactions between living
systems and molecules, especially chemicals from
outside the body.Drugs will be different in:
Size--most smallShape--to fit receptorChemical nature--acid/base
Drugs will be different in:Size--most smallShape--to fit receptorChemical nature--acid/base
Drug-body interactionDrug-body interactionPharmacodynamic:What drug does to youa) mimic or inhibit normal physiological/biochemical
processes or inhibit pathological processes in animals or(b) inhibit vital processes of endo- or ectoparasites and microbial organisms.
Pharmacokinetic:What you do to drug(absorb, distribute,
metabolize,eliminate)
Pharmacodynamic:What drug does to youa) mimic or inhibit normal physiological/biochemical
processes or inhibit pathological processes in animals or(b) inhibit vital processes of endo- or ectoparasites and microbial organisms.
Pharmacokinetic:What you do to drug(absorb, distribute,
metabolize,eliminate)
Get the drug in:Get the drug in:
OralInhaleTopicalTransdermalSubcutaneousIntramuscularBuccalSublingualRectal
Parenteral---must skip the GI tract to avoid stomach acid(some penicllins and insulin)
OralInhaleTopicalTransdermalSubcutaneousIntramuscularBuccalSublingualRectal
Parenteral---must skip the GI tract to avoid stomach acid(some penicllins and insulin)
DRUG GROUPSDRUG GROUPSAntibioticsAntifungalsAntiviralsAntiretroviralsAffective disordersInsomniaCNS disordersRespiratory agentsGastrointestinal agentsUrinary systemCardiovascularAnticoagulantHyperlipidemiaNarcotic and opoid analgesicsNon-narcotic analgesicsThyroid
AntibioticsAntifungalsAntiviralsAntiretroviralsAffective disordersInsomniaCNS disordersRespiratory agentsGastrointestinal agentsUrinary systemCardiovascularAnticoagulantHyperlipidemiaNarcotic and opoid analgesicsNon-narcotic analgesicsThyroid
DRUG GROUPS CONTDRUG GROUPS CONT
Hormone replacementBone diseaseCorticosteroidsHypoglycemicTopicalchemotherapy
Hormone replacementBone diseaseCorticosteroidsHypoglycemicTopicalchemotherapy
drug interactionsdrug interactions drug-drug interactions--- addition--combined effect of 2 drugs antagonism---drugs work against each
other potentiation----one drug increase effect of
the other synergism----combined effect is more
intense or longer
drug-disease interaction-some diseases may inhibit effects of drugs.
drug nutrient interaction--poor nutrition may affect metabolism
drug-drug interactions--- addition--combined effect of 2 drugs antagonism---drugs work against each
other potentiation----one drug increase effect of
the other synergism----combined effect is more
intense or longer
drug-disease interaction-some diseases may inhibit effects of drugs.
drug nutrient interaction--poor nutrition may affect metabolism
drug interactionsdrug interactions drug-food interaction----some drugs have
better absorption with fatty meal some drugs have decreased absorption
with food grapefruit juice may affect some drugs warfarin interacts with vitK foods. newborns---organs not developed until
1yoa geriatric---pharmacokinetics changes with
age due to GI, cardiac,ect changes.
drug-food interaction----some drugs have better absorption with fatty meal
some drugs have decreased absorption with food
grapefruit juice may affect some drugs warfarin interacts with vitK foods. newborns---organs not developed until
1yoa geriatric---pharmacokinetics changes with
age due to GI, cardiac,ect changes.