Pharmacodynamics
description
Transcript of Pharmacodynamics
PharmacodynamicsPharmacodynamicsBSCI 493BSCI 493
March 2008March 2008
Pharmacodynamics:Pharmacodynamics:
The study of the biochemical The study of the biochemical and physiological effects of and physiological effects of
drugs on the body or drugs on the body or microorganisms within or on microorganisms within or on
the bodythe body
Effects on the BodyEffects on the Body
4 Main Drug Actions:4 Main Drug Actions:
DepressingDepressing StimulatingStimulating Destroying CellsDestroying Cells Replacing CellsReplacing Cells
Desired ActivityDesired Activity Cellular membrane disruptionCellular membrane disruption Chemical reactionChemical reaction Interaction with enzyme proteinsInteraction with enzyme proteins Interaction with structural proteinsInteraction with structural proteins Interactions with carrier proteinsInteractions with carrier proteins Interaction with ion channelsInteraction with ion channels Ligand binding to receptorsLigand binding to receptors
Hormone receptorsHormone receptors Neuromodular receptorsNeuromodular receptors Neurotransmitter receptorsNeurotransmitter receptors
Terms to RememberTerms to Remember
Therapeutic effectsTherapeutic effects Site of actionSite of action Mode of actionMode of action Mechanism of actionMechanism of action