Pharmacodynamics

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Pharmacodynamics Pharmacodynamics BSCI 493 BSCI 493 March 2008 March 2008

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Pharmacodynamics. BSCI 493 March 2008. Pharmacodynamics:. The study of the biochemical and physiological effects of drugs on the body or microorganisms within or on the body. Effects on the Body. 4 Main Drug Actions: Depressing Stimulating Destroying Cells Replacing Cells. - PowerPoint PPT Presentation

Transcript of Pharmacodynamics

Page 1: Pharmacodynamics

PharmacodynamicsPharmacodynamicsBSCI 493BSCI 493

March 2008March 2008

Page 2: Pharmacodynamics

Pharmacodynamics:Pharmacodynamics:

The study of the biochemical The study of the biochemical and physiological effects of and physiological effects of

drugs on the body or drugs on the body or microorganisms within or on microorganisms within or on

the bodythe body

Page 3: Pharmacodynamics

Effects on the BodyEffects on the Body

4 Main Drug Actions:4 Main Drug Actions:

DepressingDepressing StimulatingStimulating Destroying CellsDestroying Cells Replacing CellsReplacing Cells

Page 4: Pharmacodynamics

Desired ActivityDesired Activity Cellular membrane disruptionCellular membrane disruption Chemical reactionChemical reaction Interaction with enzyme proteinsInteraction with enzyme proteins Interaction with structural proteinsInteraction with structural proteins Interactions with carrier proteinsInteractions with carrier proteins Interaction with ion channelsInteraction with ion channels Ligand binding to receptorsLigand binding to receptors

Hormone receptorsHormone receptors Neuromodular receptorsNeuromodular receptors Neurotransmitter receptorsNeurotransmitter receptors

Page 5: Pharmacodynamics

Terms to RememberTerms to Remember

Therapeutic effectsTherapeutic effects Site of actionSite of action Mode of actionMode of action Mechanism of actionMechanism of action