PersonnelPlacement

SCIENCE publishes each Friday, except the last Fridayof the year. Advertising is accepted only in writing; noabbreviations. Any deadline in ad must be at least 2weeks after date of issue in which ad appears. Also,personnel advertising is accepted only with the under-standing that the advertiser does not discriminateamong applicants on the basis of race, sex, religion,age, color, national origin, handicap, or sexual prefer-ence. SCIENCE reserves the right, in its discretion, todecline to publish advertisements submitted to it.

UNE CLASSIFIED ADVERTISING DEADLINES:Thursday, 10 a.m., 2 weeks prior to issue date (mailedon issue date). For deadlines for display advertising,please contact Scherago Associates.

POSITIONS WANTED: 40¢ per word, plus $4 for use ofbox number, per week. $10 minimum, per week.Prepayment required. This rate is available only toindividuals seeking jobs.

UNE CLASSIFIED (POSITIONS OPEN, COURSES,FELLOWSHIPS, MARKETPLACE, and so forth):$38.00 per line; $380 minimum, per week (minimumcharge covers one inch on a single column; one inchequals 10 lines of 52 characters and spaces per line).No charge for use of box number. No agency commis-sion for Ids less than 4 inches. No cash discount.Prepayment required for all foreign ads. Purchaseorders and/or cover letter including billing addressrequired for all other advertising.

To ESTIMATE ad coat:Structure ad copy on a separate page, on lines of 52characters and spaces. Include any desired heading.Each line of heading, and/or extra line spaces, and allpartial lines (including centered reply information) arecounted as full lines. Ad titles located within the textare printed in boldface caps and are only 32 charac-ters per line. In ESTIMATING the cost, multiply totallines x $38.00 = approximate cost of ad. (This is anapproximate cost ONLY: Allow for variation betweenestimated lines and actual typeset lines and the result-ing final cost. Purchase orders must allow for somedegree of flexibility and/or adjustment.)

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Send copy for all Positions Wanted ads and LineClassifled ads less than 1/6 page in size (39 lines) to:

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1333 H Street, NWWashington, DC 20005

POSITIONS WANTED

Biochemical Pharmacologist, Ph.D. with group leader-ship experience in industrial laboratory for cardiovascularand CNS research, proven publication record, fluent inFrench and Spanish. Seeking challenging and responsibleposition in industry at the international evel, domestic orforeign. Box 115, SCIENCE.

Biologist/Physiologist, Ph.D., research on the physiol-ogy of the gastrointestinal tract, vitamin metabolism,chromatography, solid phase extraction, atom absorp-tion, HPLC, enzyme assays, immunocytochemistrv.Seeking a research position in physiology or related fieldin an industrial, academic, or clinical laboratorv. 1910West Main Street, Richmond, VA 23220.

POSITIONS WANTED

Immunologist, Ph.D. Specialist in cellular immunolo-gy, hybridomas, monoclonal antibodies, and lympho-kines. Experience in biotechnology research and develop-ment in cancer immunotherapeutics. Seeking position inindustrial or academic laboratory investigating immuno-logical approaches to human disease. Excellent back-ground and references. Box 118, SCIENCE.

Immunologist, Ph.D. Principal investigator with 14years of broad background in inflammatory mediatorsand platelet and leukocyte function. Some vaccine devel-opment. Experience as a coinvestigator in clinical re-search and development within pharmaceutical industrv.Seeking industriaf research and development position asgroup leader or senior scientist. Box 107, SCIENCE.

Molecular Biologist, Ph.D. Research in gene regulationofoncogenes and Ig genes. Broad knowledge in a varietyof techniques used in cell culture, immunology, molecu-lar genetics and transgenic mice. Seeks group leaderposition in academidiindustrial laboratory in Europe.Excellent publication record. Box 117, SCIENCE.

Toxicologist. Ph.D., Board-certified with extensive in-dustrial and governmental experience (laboratorv andnon-laboratory). Seeks industrial/consulting position inthe Mid-Atlantic area. Box 116, SCIENCE.

POSITIONS OPEN

AIR POLLUTION RESEARCHERSMust have B.S. degree with major work in engineer-

ing, math, or physical/biological/environmental sciencesand 4 years of experience in those areas including 1 yearof specialized experience in research consultation anddetermination of research design/methods for studies inair pollution or related field. Salary: $3393 to $4096 permonth. Call: 916-322-8205 collect before 20 August1988 or write to: Air Resources Board, 1234 U Street,Sacramento, CA 95818.

ASSISTANT DIRECTORALABAMA AGRICULTURALEXPERIMENT STATIONAUBURN UNIVERSITY

Provide leadership for research program managementand extramural support. Ph.D. within agricultural, for-estrv and related sciences. Have understanding of land-grant system and be effective communicator. Successfulexperience in extramural grant funding. Must be eligiblefor tenure in your discipline. Position available 1 January1989. Curricula vitae will be reviewed starting 15 Sep-tember 1988. Send curriculum vitae to: Dr. Paul K.Turnquist, Chairman Search Committee, Depart-ment of Agricultural Engineering, Auburn Universi-ty, AL 36849-5417. Minorities and ftmales encouraged toapply. Atn Affirmative Action/Equal Opportunity Employer.

ASSISTANT/ASSOCIATE PROFESSOR. TheDepartmnents of Neuroscience and Neurological Surgeryat the University of Florida College of Medicine areseeking to fill a tenure-track position with an anticipatedstarting date of 1 March 1989. The focus of this search isfor an individual with research interests that couldintegrate with our Spinal Cord Injury and RegenerationProgram which presently emphasizes neural tissue trans-plantation, neuroanatomy, electrophysiology, and behav-ior (i.e., psvcho-physics). Applications are being soughtfrom individuals with complementary expertise (e.g., inneuropharmacology of spinal cord function, identifica-tion and expression oftrophic and/or tropic factors in theinjured CNS, or neuroimmunology). The successfulcandidate will be expected to establish an independentresearch program and to participate in teaching medicaland graduate courses. We encourage applications frompersons having a Ph.D. and/or M.D. degree and aminimum of 2 years of postdoctoral experience.

Persons interested in applying for this position shouldsend their curriculum vitae, a brief overview of presentand future research directions, and the names, addresses,and telephone numbers of four references bv 1 October1988 to: Dr. Paul J. Reier, Department of Neurologi-cal Surgery, University of Florida College of Medi-cine, JHM Health Centcr, Box J-265, Gainesville, FL32610-0265.

The University ofFlorida is an Affirmative Action and EqualOpportunity Employer.

POSITIONS OPEN

ASSISTANT PROFESSORCOGNITIVE NEUROBIOLOGYUNIVERSITY OF CALIFORNIA,

IRVINEApplications are invited for a tenure-track position at

the level of assistant professor in cognitive neurobiology.Preference will be given to applicants who have demon-strated expertise in the organization of neural systemsunderlying cognition, cognitive changes induced by dis-ease and aging, and/or neural modelling of cognitiveprocesses.The Department of Psychobiology emphasizes inter-

disciplinary approaches to the study ofthe nervoussystem and behavior. The current major research themesof the Department are development, reorganization fol-lowing injury and disease, and learning and memory.

Please submit by 1 October 1988, curriculum vitae,description of research interests, and three confidentialletters of recommendation to: Dr. James L. McGaugh,Chair, Department of Psychobiology, University ofCalifornia, Irvine, CA 92717.UCI is an Affirmative Action/Equal Opportunity Employer.

ASSISTANT PROFESSORMOLECULAR NEUROBIOLOGYUNIVERSITY OF CALIFORNIA,

IRVINEApplications are invited for a tenure-track position at

the level of assistant professor in molecular neurobiolo-gy. Preference will be given to applicants who havedemonstrated expertise in applying molecular biology toresearch problems within the themes emphasized by ourDepartment.The Department of Psychobiology emphasizes inter-

disciplinary approaches to the study of the nervoussystem and behavior. The current major research themesof the Department are development, reorganization fol-lowing injury and disease, an leaming and memorv.

Please submit by 1 October 1988, curriculum vitae,description of research interests, and three confidentialletters of recommendation to: Dr. James L. McGaugh,Chair, Department of Psychobiology, University ofCalifornia, Irvine, CA 92717.UCI is an Affirmative Action/Equal Opportunity Employer

ASSISTANT/ASSOCIATEE/PROFESSOR-Ten-ure-track position available immediately for a molecularbiologist with experience in prokaryotic molecular genet-ics. Independen y funded research programs and experi-ence directing graduate students at the Ph.D. level arerequired. Candidate will also participate in ongoingprojects in molecular analysis of virulence factors includ-mg surface adhesins of oral bacteria. Salary and title arecommensurate with experience. Send curriculum vitaeand three names of references to: Dr. Pamela Jones,State University ofNew York at Buffalo, Departmentof Oral Biology, 3435 Main Street, 109 Foster Hall,Buffalo, NY 14214. An Equal Opportunity/AffinnativeAction Employer.

ASSISTANT/ASSOCIATE PROFESSOROF PATHOBIOLOGY

The Department of Cancer Biology at the HarvardSchool of Public Health is seeking an assistant or asso-ciate professor of pathobiology. Background and train-ing appropriate for conducting research on viral diseasesis required. Knowledge of virology, pathology, andinfectious disease immunology is highly desirable. Expe-rience studying chronic infections prevalent in develop-ing countries is particularly valuable. The successfulcandidate will participate in the teaching of graduatelevel courses on viral diseases and supervise doctoralstudents conducting research in this area.

Interested candidates should send curriculum vitaewith a complete bibliographv, representative recent re-prints, a description of research and teaching interests,and the names and addresses of three references as soonas possible to:

Mrs. Ann R. OliverAssociate Dean for Academic Administration

Harvard School of Public Health677 Huntington Avenue

Boston, MA 02115Harvard Utniversity is committed to increasing representation

ofwomen and minority members among its faculty and particu-larly encourages applicationsfrom such candidates.

PERSONNEL PLACEMENT 369

Simultaneous Interpreter and Translator from Japa-nese publications, patents, and technical report. P.O.B.211063, Columbus, OH 43221.

IS JULY 1988

POSITIONS OPEN

ASSOCIATE CHEF OF STAPFASSISTANT/ASSOCIATE/FULL PROFESSOR

(Department as appropate) AND ASSOCIATECHIEF OF STAFF FOR RESEARCH AND DE-VELOPMENT, VA MEDICAL CENTER (VAMC).The San Diego VAMC is a hospital filly affiliated withthe University of Califoriia, San Diego (UCSD) Schoolof Medicine. The position's pnmary function is adminis-tration of the Medical Center's Research and Devlop-ment Program which includes assisting investigators mall administrative, scientific, and techncal matters per-mining to the conduct oftheir research. It is essential that

candidtes for the position be nationally recognizedscientists with well established records of research pro-ductivity who have received msearch funding from peerreviewed sources. Candidates should also have significantadministrative experience. Familiarity and experiencewith the Veterans Administration Research Service isdesirable, but not essential. Candidates should submitVA application form for physicians (VA Form 10-2850)and curriculum vitae with bibliography and history of allVA and extra-VA research support. Candidates shouldbe physicians, however, in an exceptional circumstancethe ChiefMedical Director can approve the appointmcntof a Ph.D. Ph.D. candidates should submit a PersonalQualifications Statement (SF 171) and curriculum vitaewith bibliography and history of all VA and extra-VAresearch support. Salary related to level of appointmentand determmied by the established salary schedules oftheVeterans Administration and the University of Califor-nia, San Diego School of Medicine. Reply to: JerroldOlefdky, MD., Chairman, Search Commit(ACOS/RED) (V-111G), VA Medical Center, 3350LA Jolla Vilbge Drive, San Diego, CA 92161. The SanDiego VAMC and UCSD are Equal Opportunity/AffirmativeAction Employers. Closing date 26 August 1988.

BIOCHEMISTRY POSTDOCTORAL RE-SEARCH POSMON at Laser Institute on mammali-an tissues light interactions: Position available for indi-vidual intereste in working in the new frontier ofopticalsperoscopy with mammaan cancer and normal tissuesand cels. Ph.D. required with previous expericence inbiochemistry and mammalian tissue and cclls. Opticalspectroscopy desirable. Annual salary $21,000 plus fullmedical and fringe benefits. Send rdsumi withthree ref ces to: Dr. L R Alfano, IUSL, Ihe CityCollege ofCUNY, New York, NY 10031. Telephone:212-368-1017.

BIOMEDICAL TECHNOLOGISTSCedars-Sinai Medical Center has two biomedical tech-

nolobist positions availabk, one in medical genetics andone in medicine. Both positions rquwre prior expenencein molecular biology laboratory, tissue cuture, MNA andDNA probes, Southern Blot analysis and a reevantBachelor's degree.For immediate consideration, please send resume to:

Marjorie AlienTdephone: 213-855-5504

CedarsSinai Medical Center8700 Bverly BoulevardBrown IBuikding, lst FloorLos Angdes,a 908

CLINICAL PATHOLOGY. The Department ofPathology at the University of California, Los Angeles(UCLA) School ofMedicine has JUNIOR FACULTTYPOSMIIONS availablc in hematopathology and micro-biology bqNinning on or after 1 January 1 and clnicalchemistry/toxicology-therapeutic drug momtorng andtransfusion medicine beginbing 1 July 1989. Quilifica-tions indude an M.D. degree, certification in clinical orspecialty pathology or equivalent experience, demon-strated rsearch ability and potential for the developmentof an independent research program. Applications in-cluding curriculum vitae, sunnary of research interests,and names and addresses of four frefnces should besent to: P. A Cancilla, M.D., Chairman, Departmentof Pathology, UCLA School ofMediine, Los Ange-les, CA 90024-1732. UCLA is an Equal Opportnuty/Afirmative Action Employer. Minority and women candidatesare encouraged to apply.

370

Department of Cell BiologyDuke University Medical CenterDuke University is seeking candidates for theposition of Professor and Chairperson of its newlycreated Department of Cell Biology. Respon-sibilities include providing leadership for researchand teaching in the area of cell biology in theSchool of Medicine. Qualifications include a dis-tinguished academic record and administrativeexperience in an academic environment.

The position will be available in the Fall of 1989.Applicants should send a copy of their curriculumvitae with references and other credentials to:Cell Biology Search Committee, Box 3701,DUKE UNIVERSITY MEDICAL CENTER, Durham,North Carolina 27710.

Du keeUniversity

Duke University is an Equal Opportunity!Affirmative Action Employer

The Office of Naval Research (ONR) is seeking an outstanding individual to serve in this Civil Service position in the Sen-ior Executive Service. Salary range is $64,700 to $73,400, depending on qualifications. In addition to salary, career SESappointees are eligible to compete for performance awards and bonuses.The Director, Ocean Engineering Division is responsible for providing leadership, coordination and direction for ONR's$16M fundamental research programs in ocean technology, coastal sciences, research facilities and remote sensing. Thegoal of the Division is to understand the interactions of ocean processes with man-made structures, and sensors and sys-tems. The Division Director is the scientific administrator of ONR R&D activity in the described fields with full responsibilityfor staffing his/her program, establishing overall priorities and procedures, and recommending change in program objec-tives and policies to the Director, Ocean Sciences Directorate. The Division Director serves as the principal consultantto the Navy on developing naval applications in ocean engineering and related fields.Candidates should possess a Ph.D. or equivalent in engineering, oceanography or physics and have significant experi-ence in ocean engineering or a related field. Considerable experience in the administration and management of researchand its application to development is also required.Interested persons should submit a Standard Form 171, Application for Federal Employment (available at Federal JobInformation Centers or from the address below) and a resume including a list of publications, to,

OFFICE OF THE CHIEF OF NAVAL RESEARCHCivilian Personnel Division, Code 01242P, Attn: Announcement 88-45 (S)

800 North Quincy Street, Arlington, VA 22217-5000Applications will be accepted through 19 August 1988 and must be received by that date. Applicants are requested to com-plete the appropriate supplemental forms. For further information and supplement forms, please call (202) 696-4705.

U S CITIZENSHIP REQUIRED * AN EQUAL OPPORTUNITY EMPLOYER

PERSONNEL PLACEMENT 371

EDUCATION COORDINATORThe American Association for the Advancementof Science, a prestigious science associationlocated in downtown Washington, D.C. has animmediate need for an Education Coordinator.

Qualified candidate will have a doctorate inscience, science education, or a related disci-pline, and experience as a teacher, supervisor,or administrator in the elementary or second-ary schools. Must understand the social andpolitical structure of the education system inthe United States. Experience in coordinatingeducation projects that involve states, schooldistricts, and universities and familiar with allaspects of curriculum development. Collegial-ity, inventiveness, energy, commitment to edu-cational reform, and the ability to facilitate thework of others will be major considerations forthe position.

For immediate consideration, please submityour resume and salary history in confidenceto:

Debra WrightAmerican Association for theAdvancement of Science

Personnel Office1333 H Street, N.W.

Washington, D.C. 20005

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IS JULY I988

ODENSE UNIVERSITY, DENMARKPROFESSOR OF ECOLOGICAL

PHYSIOLOGYA position as Professor is vacant at the Institute of Biology.The present salary is Dkr. 377.198,19 per year.It is desirable that applicants have a broad background know-ledge of biology and research experience in ecological physio-logy, preferably in the aquatic environment.Research at the Institute mainly concerns environmental res-ponses and adaption mechanisms. The Institute is well equip-ped with modern apparatus and has a field laboratory with run-ning sea water. Additional information, including the full text ofthe advertisement, can be obtained information, including thefull text of the advertisement, can be obtained form the Head ofthe Department.Applications should be addressed to the Queen of Denmarkand sent in 5 copies (5 copies of publications) to Odense Uni-versity, Campusvej 55,5230 Odense M, Denmark.The application must include information regarding the appli-cant's pedagogical qualifications and be received no later thanSeptember 1, 1988 kl. 12.00.

,zJ

OLIGONUCLEOTIDECHEMIST

We seek an individual to operate a central facilityin nucleic acid chemistry in the Cancer Center ofthe Worcester Foundation for Experimental Biology.This position, and the facility, is supported by a NCICancer Center core grant (Dr. Thoru Pederson,Principal Investigator). The appointee will beresponsible for automated synthesis of oligonucleo-tides for cloning, sequencing and hybridizationprojects in the Center, and for organic synthesis ofmodified nuclpotides and oligonucleotides. Thefacility is associated with a group working ontherapeutic applications of antisense oligonucleo-tides (Drs. Paul Zamecnik and John Goodchild), andthe appointee will have scientific Interactions withthis and other nucleic acid-gene expressionresearch groups In the Center. A Ph.D. degree inOrganic Chemistry Is preferred although othercandidates with relevant experience in oligo-nucleotide chemistry will be considered. TheWorcester Foundation is a nonprofit, basic researchinstitute located on a 100-acre wooded campus 38miles west of Cambridge. Send curriculum vitaeand a synopsis of research interests and careerobjectives including the names of three individualswho can be contacted to: OligonucleotideChemi, C/O Peronnel Office.

Worcester Foundatlon forExperimental Biology222 Maple Avenue

Shrewsbury, MA 01545 USAAN EQUAL OPPORTUNITY/AFFIRMATIVE

ACTION EMPLOYER M/FIH

AERONOMER - BRANCH CHIEFSPACE SCIENCE LABORATORY

NASA/George C. Marshall Space Flight CenterHuntsville, Alabama 35812

The Solar-Terrestrial Phyics DMsion Is seeWng a highly qualfied individual toseve as Chief of the Atomic Physics and Aronoy Branch. The Branch Isinvlvd In an active research program In the physics and ch stryd the upperatnophere and bnosphere. Research Programs are currently underway Instratospheric, mo-pheric, rm sp, and bw: mognetopheri photo-chnistry, enrget, and dynamics. Instrumwnt forSpao Shuttle, satekite, andhigh altitud, baloon Investigaions of thes regions currently emphasize state.d-theartopticx systems overwavelengthe atending fromtheeotrem ultraviolettoth infrared. Well-equippd laboratory facitie ae avalblo within the Branch tosupport instrument design, development, and caibratlion. Computer facikitlsavalabie nlude VAX minicorrputers togethr with IBM and CRAY mahin".Extensive theortical modeling of the thermophe,' ionosphere, and plasmas-pher is undwrway, and efforts will be made tosrng modeing d the middleatmosphere. In addition toperforring hisblhown reserch, the hwncum,nwill beexpected to guide the work of the Branch and to purue new directions asWropriate. Salary will be $46,679 - $71,377. depending on -experice andqualfications. Further technical nformation conowming the posion can be db-wined by calling Dr. M. R. Torr (205-544-7676).

Qualltngioa: The sucoessful candidat must bea recognizedreserch sciontstwith administrative Interes. In addition, candidates mt have corwnpted an approprite professional acadmic background in science adorengsr g.ph-have increangly respoble experience direty relad to the dutie of theposiion.

Topply,forwardaresumsorAppcationforFedera Epklnpbt(SF-171), aongwith aliktdpubliatkns,to NASAIGeorgeC. MarshallSpac FligtCenter, CM44/S. Payne. Huntsville, AL 35812. Forms rwbeobtainedbycaling205.544-7530.Dedline for fiNng i September 30, 1968.

NASAn Equal Opportunity U.S. Citizenship RequiredEmployer

CHEMEX PHARMACEUTICALS/YALE UNIVERSITY

Two positions are available at the level of a postdoctoralfellow to work on a "Oligonucleotide Directed Photoche-motherapy" project, which involves photomodification ofanti-sense DNA with photoactivable compounds; character-ization of nuclease sensitivity; membrane transport andtarget specificity.Requirements include a Ph.D. in Biochemistry or MolecularBiology with 0-3 years postdoctoral experience in MolecularBiology. Experience in HPLC, Oligonucleotide and DNAsynthesis and purification is preferred, but not required.Highly competitive salary commensurate with experience.The successful candidate will work in the Department ofDermatology at Yale University in New Haven for a period oftwo years at the end of which that individual will beconsidered for a position at CHEMEX PHARMACEUTI-CALS to continue research in the area of molecular biologyof skin diseases and disorders and discovery of new drugs.For confidential consideration please forward your personalletter and curriculum vitae to both:

Dr. Frank GasparroDeparbnent of DermatologyYale UniversityP.O. Box 3333 (HUNTER A-615)New Haven, Conn. 06510Dr. Atula KhandwalaVice President, ResearchCHEMEX PHARMACEUTICALS, INC.1401 Seventeenth St., Suite 850Denver, Colorado 80202

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IVERSITAS(MIINI

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POS$TDO9¢CTORAL

POSITIONS

As one of the most dynamic and progressivepharmaceutical and medical research organi-zations in the world, Scientists who join

Hoffmann-La Roche find professional challenges and rewardsthat can not be equalled. We currently have several postdoctoralopenings:

ASTHMA/ALLERGY RESEARCHOne position will involve investigating the regulation of signaltransduction in models for mast cell function. To qualify, youwill need a PhD in biochemistry/pharmacology and experiencewith SDS-PAGE electrophoresis. Familiarity with Ca+2 mea-surement techniques, and demonstrated success in the fields ofprotein and lipid biochemistry are preferred. Please refer toPosition AG.

The other position will involve investigating mechanisms andmodulation of airway hyperreactivity/late phase asthmaticresponses, including the role of inflammatory mediators andeosinophils in pulmonary disease. A PhD in biochemistry, phar-macology or physiology is required; experience with inflam-matory mediators is desirable. Please refer to Position WS.

CARDIOVASCULAR RESEARCHThis position will involve studying the cellular and metabolicbases of ischemia/reperfusion injury. A PhD in biochemistry orcardiac physiology is required; experience with ex vivo perfusedheart is desirable. Please refer to Position DJ.

Hoffmann-La Roche offers an environment conducive todiscovery, as well as comprehensive compensation packages.For confidential consideration, please send your curriculumvitae, indicating position of preference and salary requirements,to: Ms. R. Chiaramonte, Hoffmann-La Roche Inc., Nutley, NewJersey 07110. We are an equal opportunity employer.

@ Hoffmann-La RocheWorking Today For

A Healthier Tomorrow.

111* i.iII[@].kO]UU.II.IE..PRODUCT MANAGEMENT To fulfill IBI's dedication to supplying high quality, innovative products to the

molecular biology research market, we are expanding our marketing group to includeproduct managers for enzymes and for DNA synthesis.

These exciting positions require skills in marketing, product development and ininterfacing with researchers on the cutting edge of molecular biology.

The ideal candidates will have first hand experience in the Marketing or Sales ofsophisticated laboratory equipment or research products to the life sciences market.

RECOMBINANT DNA This position is an exciting opportunity for a molecular biologist to combineWORKSHOP INSTRUCTOR teaching, marketing and travel. Responsibilities include scheduling, managing and

teaching 4-day training programs in recombinant DNA technology. The ideal candi-date will have a Ph.D. in molecular biology or a related field, extensive laboratoryexperience in gene cloning and exceptional organizational and interpersonal skills.Approximately 50% travel is required.

DNA SEQUENCING This position is an exciting opportunity for a molecular biologist to combineWORKSHOP INSTRUCTOR teaching, marketing and travel. Responsibilities include developing, scheduling,

managing and teaching short courses in dideoxy sequencing technology. The idealcandidate will have significant laboratory experience in sequencing DNA and excep-tional organizational and interpersonal skills. Approximately 50% travel is required.

SOFTWARE PRODUCTSPECIALIST

IBI is currently seeking a Programmer/Biologist to direct the development andmaintenance of our sequence analysis software for microcomputers. The idealcandidate must have a graduate degree in the Biological Sciences and have a proventrack record in developing software for microcomputers. A proficiency in C is re-quired and experience with both PC-DOS and Macintosh systems helpful. A

Interested candidates should mail their resumes to:Position TitleInternational Biotechnologies, Inc.A Kodak CompanyP.O. Box 9558 * New Haven, CT 06535

'A

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POSITIONS OPEN

CELL BIOLOGY FACULTYThe Biology Division at the California Institute of

Technology hias a tenure-track faculty position open in

the areas of cell biology or cellular neurobiology. Thesefields are broadly defined and include biophysical, struc-tural, biochemical, and immunological approaches. Ap-plications from women and minority candidates are especiallyencouraged. Interested persons should submit curriculumvitae, a statement of research interests, and the names ofthree references to:

Cell Biology Search Committeec/o Candace Hochenedel

Division of Biology 216-76California Institute of Technology

Pasadena, CA 91125

New Endowed CHAIR IN GASTROENTEROL-OGY at University of Califomia, Los Angeles (UCLA)School of Medicine, Dorothy and Leonard Straus Pro-fessorship. Search committee seeking accomplished clini-cal gastroenterologist of great distinction in science.UCLA is an Equal Opportunity-Employer. Send curriculumvitae to: Sherman Mellinkoff, M.D., Department ofMedicine, UCLA School of Medicine, Los Angeles,CA 90024.

CHAIRMANDEPARTMENT OF PEDIATRICS

The University of Florida College of Medicine seeks adistinguished academic pediatrician to serve as Professorand Chairman of the Department of Pediatrics. Appli-cants should have an M.D. degree, Board Certification inPediatrics (or equivalent), a record of significant accom-plishments in research, clinical skills in pediatrics, and adear commitment to the teaching of medical studentsand to post-graduate education. Applications, includingcurriculum vitae, bibliography, and the names and ad-dresses of at least five persons that may be contacted forreference should be sent before 26 August 1988 to:Jerome H. Modell, M.D., Chairman, Pediatric SearchCommittee, Collcge ofMedicine, University ofFlori-da, Box J-254, JHMHC, Gainesville, FL 32610. Theearliest anticipated starting date is 1 January 1989. EqualOpportunity/Afirmative Action Employer.

CONSULTINGTOXICOLOGIST

Exxon Biomedical Sciences, Inc. has an opening for aqualified toxicologist in our chemical and petroleumgroups. The successful candidate will have a Ph.D. intoxicology with 0-3 years of experience and be knowl-edgeable in the design of toxicology studies for petro-leum and chemical products. Consulting activity includesproduct line interacion, literature evaluation, generalbiomedical research as well as governmental/regulatorybody interactions and risk assessment. The positionrequires extensive consulting with Exxon Affiliates worldwide. Client interactions are an important aspect of ourwork, and thus we are seeking individuals who possessexcellent communication skills. Please forward resumeto: Human Resourmcs,

EXXON BIOMEDICAL SCIENCES, INC.CN 2350, Mettlers Road

East Millstone, NJ 08875-2350Equal Opportunity Employer M/F/H/V

CONSULTINGTOXICOLOGIST

Exxon Biomedical Sciences, Inc. has an opening for a

qualified toxicologist in our chemical and petroleumgroups. The successful candidate will have a Ph.D. intoxicology with 3-5 years of experience and be knowl-ed,eable in the design of toxicology studies for petro-leum and chemical products. Consufting activity includesproduct line interaction, literature evaluation, generalbiomedical research as well as governmental/regulatorybody interactions and risk assessment. The positionrequires extensive consulting with Exxon Affiliates worldwide. Client interactions are an important aspect of ourwork, and thus we are seeking individuas who possessexcellent communication skills. Please forward resumeto: Human Rcsources,

EXXON BIOMEDICAL SCIENCES, INC.CN 2350, Mcttlers Road

East Millstone, NJ 08875-2350Equal Opportunity Employer M/F/H/V

374

POLLUTANT TRANSPORT AND REACTIONSIN SOILS OR INDOOR ATMOSPHERES

The Lawrence Berkeley Laboratory's Indoor Environment Program isseeking highly qualified scientists to perform research on the behaviorof radon or organic chemicals inside buildings or in the ground nearbuilding foundations. A Ph.D. or equivalent Degree in Chemistry, Physics,Geology, Environmental Engineering, or related fields is required, withsubstantial experimental or theoretical capabilities applicable to investi-gation of fundamental transport and reaction processes.

STAFF SCIENTIST II (C/4743) Available for an individual who has at least 5years' experience beyond the BA Degree and has demonstrated a strongcapability for productive research in areas related to those of theprogram (see above description). Ph.D. preferred.STAFF SCIENTIST IlIl (C/4701) Requires 5 or more years' experience, inaddition to the Ph.D., and strong evidence of research and leadershipcapabilities. The successful candidate will initially perform research inexisting areas, with the expectation of developing new efforts andcontributing to the leadership of the program. Position requirescapabilities and interest in conducting fundamental research in an inter-disciplinary field, the ability to work well with and stimulate others, anda record of effective communication and publication.

Competitive salary commensurate with experience, plus comprehensivebenefits. Please send resume, including publication list, names ofreferences (must indicate Job C/4743 or C/4701) to: Employment Office,Lawrence Berkeley Laboratory, 90-1012,#1 Cyclotron Road, Berkeley, CA94720, (415) 486-4226. An Equal Opportunity Employer, M/F/H.

~ LAWRENCE

BERKELEYLABORATORY

Smith Kline & French Laboratories, in suburban Philadelphia, isseeking qualified, B.S./M.S. Analytical Chemists to join theirPharmaceutics group. Experience in instrumental analysis and wetchemical analysis is required as well as in development andvalidation of new analytical methods. Candidates with specificexperience in HPLC, GC, spectrophotometry or dissolution testingwould be highly desirable. Good interpersonal skills, a sense ofcommitment and teamwork and a preference for a fast-paced,creative environment would mark the ideal candidates.We offer an excellent compensation and benefits plan andopportunities for professional growth and development. Forconfidential consideration, please forward your resume and thenames of three references to Liz McKendry, Associate EmploymentAdministrator, LOIO, SK&F Laboratories, P.O. Box 1539, King ofPrussia, PA 19406-0939. We are an equal opportunity employer,M/F/H/V.

A

lb

LET Corporation is a well-funded start-up company, char-tered to carry out a vigorous research and development pro-gram concerning human immune cell receptors and growthmodifiers. That program is aimed at the discovery of basicknowledge leading to the development of effective pharma-ceuticals that will impact the clinical management of disease.LET has several assets already in place including an activecollaboration with a major academic research center andnovel technology developed from progress made in itsresearch effort.LET Corporation is seeking three scientists with experienceand ability to form and lead groups in Molecular Biology, Pro-tein Chemistry, and Immunology to both discover anddevelop novel compounds for the treatment of immune sys-tem diseases. Compensation packages, including stockoptions, will be designed for each group leader. All will reportto the Scientific Director.

MOLECULAR

BIOLOGISTThis position requires a Ph.D., 4 plus years beyond the post-doctorate, with academic or industry experience in procaryoticand eucaryotic expression systems, including CHO and in anyof the following aspects of the molecular biology of humanT-cells: molecular genetics, control of gene expression, virol-ogy. The ability to make significant and original contributionsto basic science will be reflected in the publication record. Thecandidate will have supervisory experience to form and lead asmall group focused on molecular biology or viral molecularbiology and apply molecular biology to protein production.

PROTEINBIOCHEMIST

This position requires a Ph.D., 2 plus years beyond the post-doctorate, with academic or industry experience in microse-quencing, analysis of protein structure and its relationship tofunction, and protein purification, especially hormones orlymphokines, receptors and cell surface structures. The can-didate must have experience in the application of suchresearch to drug design. The candidate will have supervisoryexperience to form a small group to characterize novel pro-teins and peptides derived from the immune system and todevise means to purify and enhance the activity of such mole-cules. Preference will be given to candidates with prior expe-rience with human T-cell receptors and lymphokines.

CELLULARaIMMUNOLOGISTThis position requires a Ph.D. plus at least four years expe-rience beyond the post-doctorate in human T-cell lympho-kines and receptor structures. In addition, the candidate willhave experience in the development of monoclonals forimmune cell surface structures and proteirs and their use inelucidating the mechanisms controlling the immune response.The candidate will have supervisory experience to form agroup to identify and test receptor structures and cytokininswith pharmacological value.Interested scientists should send their CVs and telephonenumber where they can be contacted to: Ms. Annette Bass,Personnel Department, LET Corporation, 359 Allston Street,C-nbridge, Mass. 02139. All materials received will betreated as a confidential communication.

r_

C 0 R P 0 R A T I 0 N

If ResearchIs What

You Do Best...Break through to a new world ofpossibilities in biotechnology.

As the innovative leader in today's dynamic industry...biotechnology, Genetics Institute can offer you a research en-vironment that's rich in creativity and entrepreneurial spirit.Whether your background stems from academia or anotherresearch setting, we at Genetics Institute encourage our researchprofessionals to explore their talents in a stimulating, scientif-ic atmosphere. It is this type of environment that has enabledour research team to make the kind of contributions deserv-ing of our reputation in the application and creation ofrecom-binant DNA technology.

Protein PurificationWe are seeking creative individuals to develop purificationschemes for novel pharmaceuticals, such as blood cell differen-tiation factors and thrombolytic agents. Suitable applicants willhave a Ph.D. degree, a strong background in protein biochemis-try and extensive experience and interest in protein purifica-tion. The position carries direct responsibility for developingprocedures for purification of both bacterial and mammalianexpressed proteins, up to the point at which clinical produc-tion commences. Beyond this point, there will be ongoingresponsibility for biochemical aspects ofthe large scale produc-tion process. It will be essential that applicants for this key po-sition have an understanding of purification scale up and theability to interact with personnel in other disciplines, especiallyengineering and production. There will also be considerableopportunity to interact with peptide and carbohydrate chemists,as well as cell biologists, in exploring structure/function rela-tionships of protein of interest.We also have positions open at the BS/MS level in this areaand welcome applications from suitably qualified applicants.Structural Protein Chemistry

An exciting opportunity exists for a highly motivated individualto join our Structural Protein Chemistry group. This personwill be expected to provide scientific leadership in the develop-ment of strategies oriented toward the structural characteriza-tion of recombinant DNA derived pharmaceutical proteins.Candidates should hold a Ph.D. in Biochemistry, with ex-perience in protein sequencing, amino acid composition anal-ysis, chemical modification and peptide mapping strategies.Candidates with a background in exploring functional domainsin enzymes or glycoprotein hormones would be particularlywell suited. This position will offer scientists the challenge ofinteracting with experts in other disciplines such as biophysi-cal chemistry, carbohydrate chemistry and biomolecular massspectrometry and the responsibility of taking a project fromconception to completion.We also have openings for talented BS/MS level Research As-sociates interested in pursuing structure/function studies onrecombinant DNA-derived proteins. Candidates should havea general background in protein biochemistry and a workingknowledge of techniques utilized to examine protein structure(i.e. SDS-PAGE, IEF, Western Analysis, enzyme assays, and/orHPLC of peptides and proteins).These positions will be based out ofour newly renovatedfacility in Andover, Massachusetts, within commuting dis-tance to Boston and Southern New Hampshire. We offeran excellent compensation and benefits package, includ-ing relocation, as well as a stimulating scientific environ-ment and substantial growth potential. Qualifiedapplicants should forward their resumes, in confidence,to: Sheri Rist, Genetics Institute, 87 CambridgePark Drive,Cambridge, MA 02140.

An Equal Opportunity Employer

Genetics InstituteI ~~~~~~~~~

SR. RES[ARCIISCI[NTISTMolecular Biology EnzymesExperienced enzymologist required to work on thedevelopment and applications of enzymes used inmolecular biology research. The successful candidateis likely to have a PhD and postdoctoral experience inthe purification, characterization and use of enzymeswhich cleave or modify DNA.PHARMACIA P-L Biochemicals is a thriving subsidiaryof PHARMACIA LKB Biotechnology, responsible forthe development and production of molecular biologyreagents. We offer a stimulating work environment, acompetitive salary and benefits package, and the op-portunity to work close to the shores of Lake Michigan.For consideration please send your resume to:

SUSAN HOIST, ADMINISTRATIVE ASSISTANT,PHARMACIA P-L BIOCHEMICALS, INC., 2202 N.BARTLETT AVE, MILWAUKEE, WI 53202.WC' drc' dni'qUdl (opporIuflir\un 1MpI(Ar \I Il I/\.

^J PharmaciaP-L Biochemicals

"MRRINE POUCY RNRLYSr'RESERRCH RSSOCIRTE

east-Wet CenterThe East-West Center, established In 1960 by the United States Congresswhich provides principal funding. is a public nonprofit educotionalinstitution, with an international board of governors. Support also comesfrom Asian ond Pacific govemments, internationol organizations, andprivate institutions.Applications are being occepted for a Research Associate position In theEnvironment ond Policy Institute (EAPI). the chief concerns of which areproblems of environmentol quolity ond resources management. Theposition is for three years with the possibility of extensions. TheResearch Associate will work as part of a collaborotive, interdisciplinary.multinational team undertaking reseorch and other activities ptoainingto marine resources monagement. Responsibilities include policy-relatedreseorch and publication, organizing ond contributing to conferences.colloboroting in the preparotion of marine policy otases and otherpublicotions, and maintaining liaison with research personnel engoged Inoceon-related studies in the Asio-Pocific region.Rieqired QuaMlfcatleo Ph.D. in a notural or social science, or a higherdegree in another field concerned with or reloted to morine policystudies. A strong English-longuage publications record In morine policy.Professional experience in the Asio-Pocific region with first-handknowledge of at leost one country in the region as demonstrated bypublicotions or other evidence.Preered aOwilcatlons: Reoding knowledge of an Asion laonuage.Familiarity wlth the preporotion of atlases. porticularly in the field ofocean olaairs ond resources monogementSalary Betig.: $27.71 6 to $46,679 per year. depending onqualifications, plus cost-of-living allowance currently ot 22.5% (subject tochange).Submit resume with cover letter which includes title of position you areopplying for, a narrative detailing relevance of your qualifications to theresponsibilities of the position, and nomes and addresses of threeprofessionol refences. Applications must be postnarked by September15, 1988. Send to: Rebecc Dzeeo, Perseu ONk., Dept 19. Et-West Ceete, 1777 Eat-West Roed. HoMu, Nell 968U

Rn Equol Employment OppotmnltVRflrmot Action Employer

PROJECT ASSOCIATE IN CELL BIOLOGY ANDPOSTDOCTORAL RESEARCH ASSOCIATE POSITIONS

at the Integrated Microscopy Resource forBiomedical Research (IMR)

at the University of Wisconsin-MadisonTwo positions are available. The IMR offers high voltage electron microscopy, video-

enhanced light microscopy, low voltage scanning electron microscopy, and laser scanningand tandem scanning confocal microscopy.

1. PROJECT ASSOCIATE IN CELL BIOLOGY. Applicants should have a Ph.D. or anadvanced degree in cell biology and five years of practical experience in several phases ofstructural investigations with TEM and, ideally, computer-based video-enhanced micros-copy, SEM and immunofluorescence and immuno-electron microscopy. The successfulindividual will be expected: 1. to participate in Core research projects which integrate highvoltage electron microscopic analyses with video, LVSEM, and confocal imaging; 2. toCollaborate on research projects with investigators on campus and nationwide; 3. toassist and instruct users in the operation of the million volt HVEM; 4. to assist in theTraining and Dissemination activities of the IMR. Salary: $24,000-30,000 annually.

2. POSTDOCTORAL RESEARCH ASSOCIATE. Applicants should either have a Ph.D. incell biology or expect to earn this degree prior to the start of this appointment. Researchinterests in utilizing and developing the usage and integration of several sophisticatedmicroscopes for the study of cellular dynamics are particularly encouraged. Salary: NIHrates for postdoctoral investigators.

In addition, the Integrated Microscopy Resource for Biomedical Research welcomesall qualified investigators to conduct studies requiring high voltage electron microscopy(HVEM), video-enhanced light microscopy, low-voltage scanning electron microscopy, andlaser scanning and tandem scanning confocal microscopy. Travel funds for first-timeusers and short term stipends for doctoral and postdoctoral visitors are available on acompetitive basis.

Please forward a curriculum vitae with a list of individuals who could be contactedfor letters of recommendation and two recent reprints, by August 5, 1988 to:

Dr. Gerald Schatten, DirectorIntegrated Microscopy Resource for Biomedical Research

University of Wisconsin-Madison1117 W. Johnson Street

Madison, WI 53706

An Equal Opportunity Employer, M/F.

BUILDING ANEW LAB?

LET THE SCIENCE FREE PRODUCTINFORMATION SERVICE PUT YOU INTOUCH WITH THE VENDORS WHOSEPRODUCTS YOU WILL NEED.

SIMPLY WRITE US A LETTER STATINGTHE SPECIFICS ABOUT YOUR PROPOSEDLAB AND WE WILL DO THE REST.

WRITE TO:

SCIENCE MAGAZINENEW LAB SERVICE DEPT.1515 BROADWAYNEW YORK, N.Y. 10036

* POSITION AVAILABLE o

Chief, Clinical Pharmacology Research BranchAlcohol Drug Abuse, and Mental Health Administration

Public Health Service * Department of Health and Human Services

The Alcohol, Drug Abuse, and Mental Health Administration invitesnominations and applications for the position of Chief, ClinicalPharmacology Research Branch.

This is a Senior Executive Service position in the career civil service,with an annual salary range of $65,994 to $73,400. Physicians mayalso be eligible for a Physician's Comparability Allowance of up to$20,000 per year. The position is located at the Addiction ResearchCenter (ARC) in Baltimore, Maryland.

The Chief, Clinical Pharmacology Research Branch, ARC, plans,develops, and oversees the Branch's programs which are carried outwith volunteer subjects (utilizing a 15-bed inpatient ward in addition tooutpatient facilities) and which test various drugs for dependence po-tential; develops new pharmacological treatment; analyzes themetabolic pathway of drugs; and devises drug addiction systems forscreening drugs in body fluids. The Chief provides scientific leadershipand technical guidance to a multidisciplinary staff of 15, and allocatesa budget of approximately $4.2 million. The Chief also plans andconducts independent research and conducts collaborative researchwith investigators of ARC, as well as with scientists of otherorganizations.

Minimum qualifications requirements include the following: a degreeof Doctor of Medicine from an AMA approved medical school, or aDoctor of Osteopathy degree from an approved school. In addition, theapplicant must possess a permanent and full license to practicemedicine in a State, the District of Columbia, the Commonwealth of

Puerto Rico, or a territory of the United States. Professional backgroundand/or education must indicate an extensive knowledge of researchmethodology. Applicants must demonstrate progressively responsibleexperience in scientific research administration, and proven professionalcompetence in areas related to the intramural research function. Theexperience must show evidence of involvement in research programsconcerned with drug abuse related disorders, and demonstrate broadunderstanding of the biological, clinical, and behavioral sciences as theyrelate to the drug abuse field. Candidates must also have experience inthe management of programs; demonstrating competence to assumeleadership in planning, directing, coordinating, and allocating resources,and other responsibilities associated with executive leadership of amajor national program.

Further information about the position and qualifications may beobtained by contacting Ms. Leslie Everheart at (301) 443-5030. Appli-cations (Application for Federal Employment SF 171) accompanied bya current curriculum vitae and bibliography should be submitted to Ms.Everheart at the Division of Personnel Management Alcohol, DrugAbuse, and Mental Health Administration, 5600 Fishers Lane, Room1 5C26, Rockville, Maryland 20857. Complete application material(including the SF 1711 must be postmarked by August 31, 1988.

Applications from women and minority group members are especiallysolicited.

The Alcohol, Drug Ahuse, and Mental Health Administration is anEqual Opportunitv Emplover.

GLAXO INSTITUTE FOR MOLECULAR BIOLOGY S.A.III11 m B X

The Geneva biotechnology research unit of the largest U.K. pharmaceutical group has a vacancy for a

PROTEIN CHEMISTThe Glaxo Institute for Molecular Biology provides a molecular basis for discovering effective newmedicines. Projects include viral and fungal therapeutics, inflammatory diseases, and regulation of cellproliferation and differentiation.The Institute has a staff of over one hundred, grouped in small teams of specialists from severaldomains of modern biology. We are part of the Glaxo Group - one of the largest pharmaceuticalcompanies in the world - which has an outstanding reputation for the quality of its research andproducts.We offer an excellent salary and benefits package, with opportunities for career development in one ofthe most attractive parts of Europe.The ideal candidate will have postdoctoral research experience and a proven track record in proteinchemistry research. Experience with microbial systems would be an advantage.If you are interested in this position, please send your curriculum vitae with a list of publications and thenames of three references to: Rita Gloor, Personnel Manager, GLAXO IMB S.A., 46, route des Acacias,1211 Geneva 24, Switzerland.

I

POSITIONS OPEN

Princeton University CONNECTIONIST: The Hu-man Information Processing Group (HIPG) at Prince-ton University offers a position for a member of theprofessional research staff to coordinate a broad range ofresearch in human information processing and to con-duct research in neural networks, connectionist, or PDP-style models. The applicant should have some interest orbackground in neuro-science and its relation to neuralnetwork models and be willing to collaborate or interactwith neuroscience faculty. The application should alsohave a familiarity with main-stream cognitive scienceareas, human factors, and computational modeling moregenerally. Ph.D. required. Deadline 1 September 1988.HIPG is an inter-disciplinary group within Princeton

University consisting of psychologist, engineers, philoso-phers, linguists, and computer scientists. Its facilitiesinclude the Cognitive Science Laboratory, the InteractiveComputer Graphics Laboratory, the Robotics Labora-tory, the Engineering Anomalies Laboratory, and theCognitive Motivation Laboratorv. Princeton University isan Equal Opportunity Employer.

Address inquiries to:Search Committee

Human Information Processing GroupDepartment of Psychology

Green HaPrinceton UniversityPrinceton, NJ 08544

DIRECTOR-UNIVERSITY OF VIRGINIA

DIABETES CENTERThe Diabetes Center of the University of Virginia is

seeking a new director. The Center is a multidisciplinarvorganization within the University which supports andpromotes diabetes and diabetes-related basic and clinicalresearch and training and outreach programs. Support isprovided by a National Institutes of Health grant, theCommonwealth of Virginia and the School of Medicine.There are more than 60 investigators and cliniciansinvolved in the activities of the Center and five corelaboratories operated as research support facilities.

Candidates for the Directorship should have a strongrecord in diabetes or diabetes-related research and ad-ministrative experience. The position will include ap-pointment in the appropriate basic science and/or clinicaldepartments. Curriculum vitae and three letters of refer-ence should be submitted to: Erik L. Hewlett, M.D.,Associate Director of the Diabetes Center Box 419School of Medicine, University of Virginia, Char-lottesville, VA 22908.

DIRECTOR OF GASTROENTEROLOGY ANDHEPATOLOGY-The Department of Medicine of theJefferson Medical College is seeking a Director for theDivision of Gastroenterology and Hepatology. Respon-sibility for research, teaching and clinical programs atThomas Jefferson University. Please forward inquiriesand curriculum vitae to: Willis C. Maddrey, M.D.,Chairnan, Department of Medicine, Jefferson Medi-cal College of Thomas Jefferson University, 1025Walnut Street, Philadelphia, PA 19107. Equal Oppor-tunity/Afirmative Action Employer.

DIRECTOR OF GROSS ANATOMYUNIVERSITY OF PITTSBURGH

SCHOOL OF MEDICINEThe University of Pittsburgh, School of Medicine is

seeking a mature anatomist to coordinate the grossanatomy programs of the basic science and clinicaldepartments. Duties will involve directing the first-yearmedical student course, coordinating the fourth-yearsurgical elective course, providing some instruction forresident programs, as required, overseeing and partici-pating in surgical research and ensuring proper andefficient usage of cadavers. This is a newly createdposition in the tenure stream, designed to complementthe strengths in investigative surgery at this institution. Aprimary appointment will be offered in the Departmentof Neurobiology, Anatomy and Cell Science, with a jointappointment in the Department of Surgerv. Deadline forapplications, 30 September 1988.

Please send curriculum vitae and names of three refer-ences to: Gross Anatomy Search, c/o Raymond D.Lund, Department of Neurobiology, Anatomy andCell Science, University of Pittsburgh, School ofMedicine, Pittsburgh, PA 15261. The University is anEqual Opportunity/Affirmative Action Employer.

378

POSITIONS OPEN

DIRECTOR, CENTER OF EXCELLENCE-FIELD BIOLOGY, Ph.D., experimental ecology, 12months. Develop an externally funded research prograrn.Fifty percent administration, 50% research. Successfulbackground in external funding required. Salary com-mensurate with experience. Send transcripts, curriculumvitae, and three letters of recommendation to: Dr. B. P.Stone, Chairman, Biology Department, Austin PeayStatc University, Clarksville, TN 37044. Closing date:15 December 1988 or until filled. Appointment 1 Au-gust 1989. APSU is an Equal Opportunity/AffirmativeAction Employer. Minorities, women, and members of otherprotected groups are encouraged to apply.

DIRECTORENVIRONMENTAL RESEARCH LABORATORY

GULF BREEZE, FLORIDA$65,994 to $71,910

U.S. Environmental Protection Agency (EPA) is seek-ing highly qualified candidates for the position of Direc-tor, Gulf Breeze Environmental Research Laboratorv.The Director is responsible for an applied researchprogram which deveops the scientific understanding,methods, and information required by EPA in order toprotect marine ecological resources. The laboratory re-search areas include: marine ecology, microbial ecology,environmental chemistry, biology, and bio-chemistry.The Laboratory Director is responsible for the designand implementation of a long-term core scientific pro-gram of the Laboratory. The emphasis of the program ison scientific quality and relevancy to long-term ecologi-cal risks. The Director also serves as a major scientificadvisor to the Agency in the area of marine ecologicalsciences.To meet the requirements of the position, applicants

must have demonstrated experience in the conduct ofresearch and must meet the technical and executivequalifications described in the vacancy announcement.Telephone or write for a copy of the vacancy announce-ment to: Edna Morse, U.S. EPA, Executive Resourcesand Special Programs Division, PM-224, 401 MStreet, S.W., Washington, D.C. 20460. The telephonenumber is 202-382-3328.

Applications must be postmarked by 31 August 1988.EPA is an Equal Opportunity Employer.

ECOTOXICOLOGISTExxon Biomedical Sciences, Inc. has an immediate

opening for a qualified individual specializing in ecotoxi-cology and environmental hazard assessment. The suc-cessfiil candidate will have a Ph.D. in ecotoxicology or inan environmentally related field with 0-2 years postdoc-toral experience. Experience in or a knowledge of theapplication of both effects and fate data to real worldconcerns, as well as knowledge of regulatory require-ments (TSCA/PMN) would be desired. Exxon Biomedi-cal performs both consulting and laboratory toxicologyfor affiliates around the world. Its resources include state-of-the-art aquatic toxicology, environmental chemistryand mammalian toxicology laboratories. The candidatewill perform as a study monitor and internal consultingtoxicologist. Client interactions are an important aspectof our work, and thus, we are seeking an individual whohas excellent communication skills. Please forward resu-me to: Human Resources,

EXXON BIOMEDICAL SCIENCES, INC.CN 2350, Mettlers Road

East Millstone, NJ 08875-2350Equal Opportunity Employer M/F/H/V

ENTOMOLOGY: The University of Idaho an-nounces a tenure-track position ofASSISTANT/ASSO-CIATE PROFESSOR of entomology located at theSW Idaho R&E Center in Parma. The appointee will beexpected to develop a strong research program on thebiology and management of insect vectors of plantviruses, with emphasis on those pests affecting potatoesand cereals, and participate in graduate student training.Candidates must have a Ph.D. in entomology, andresearch experience or training in plant virus-vectorrelationships. Applicants should submit curriculum vitae,academic transcripts, and three letters of recommenda-tion to: Dr. C. M. Smith, Division of Entomology,University of Idaho, Moscow, ID 83843. Telephone:208-885-7544. The deadline for receiving applicationsand supporting material is 1 October 1988, and may beextended until a qualified applicant is selected. TheUniversity ofIdaho is an Affirmative Action/Equal Opportuni-ty Employer.

POSITIONS OPEN

UNIVERSITY OF COLORADODIRECTOR

MOLECULAR AND ENVIRONMENTALTOXICOLOGY PROGRAM

The School of Pharmacy at the Universitv of Coloradois seeking applicants for the directorship oe its Molecularand Environmental Toxicology Program. The appoint-ment is tenured or tenurable at the associate or fullprofessor level. Applicants should have a strong researchfocus and an established reputation for excellence inteaching and research. Research interests may includemolecular mechanisms of toxicity, immunotoxicologv,genotoxicology, or the application of molecular biologi-cal techniques to toxicological problems. Please sendcurriculum vitae, reprints, and a letter of interest, bv 29July 1988 to: Louis Diamond, Ph.D., Dean, School ofPharmacy, University of Colorado, Boulder, CO80309-0297. The University of Colorado is an AffirmativeAction/Equal Opportunity Employer.

DIRECTOR OF RESEARCH INSTITUTEDEPARTMENT OF SURGERYTHE ST. LOUIS UNIVERSITY

The St. Louis University School of Medicine seeks adirector for The Surgical Research Institute.

Qualifications include an M.D. and/or Ph.D. degreeand a record of administrative and research accomplish-ments.The Director will have primary responsibility for the

overall administration of research programs for the insti-tute. It is expected that the Director will have an activeresearch program which preferably will be in the area of,but not limited to, basic immunologv, metabolism orshock. The directorship is associated with academicappointment to the St. Louis University School ofMedicine. Interested individuals should submit theircurriculum vitae to: Chairman, Search Committee,Department of Surgery, St. Louis University Hospi-tal, 1325 South Grand Boulevard, St. Louis, MO63104. Equal Employment Opportunity/Affirmative Action.

HEAD, VIROLOGY DEPARTMENTAMERICAN TYPE CULTURE COLLECTIONPh.D. virologist with 5 to 8 vears of experience to

manage the collections of animal, plant, and molecularlycloned viruses and to develop an applicable researchprogram. Candidates must have demonstrated strongleadership, organization supervisorv skills and successfulextramural funding. Send curriculum vitae, salary re-quirements, and names of three references to: Ms. Hol-land, 12301 Parklawn Drive, Rockville, MD 20852.Equal Opportunity Employer.

Harvard University. The Department of Psychology issearching for JUNIOR APPOINTEES (initially or a5-vear term), beginning 1 July 1989 in the area ofdevelopmental psychology. Candidates should hold thedoctoral degree by the appointment date to be eligiblefor consideration. A specia interest in emotional process-es or infant perception would be desirable. In addition,competence in psvchological measurement and statisticswould be an advantage. Applications should includereprints, a current curriculum vitae, and applicantsshould ask at least three individuals familiar with theirwork to write directlv to: Brendan A. Maher, Chair-man, Department ofPsychology, Harvard University,33 Kirkland Street, Cambridge, MA 02138. Applica-tions received after 15 October 1988 may not be consid-ered. Applications from women and minority groups are espe-cially welcome.

HEBREW UNIVERSITY-HADASSAH MEDICAL SCHOOL,DEPARTMENT OF PHYSIOLOGY

Seeks a LECTURER/SENIOR LECTURER for atenure-track position to conduct independent research inany field of system, cellular or molecular phvsiology andto participate in teaching. M.D. or Ph.D. Postdoctoraltraining essential.

Persons interested in the position should send curricu-lum vitae, bibliography, relevant reprints or preprints,and three letters of recommendation to: Chairman,Department of Physiology, Hebrew University-Ha-dassah Medical School, P.O. Box 1172, Jerusalem91010, Israel bv 1 October 1988.

Preference wihl be given to an excellent candidate insystem physiology.

SCIENCE, VOL. 241

POSITIONS OPEN

GROWTH FACTOR SENIOR SCIENTISTCephalon, Inc., a neurscenc-bioted olo compa-

ny, is seeking an energetc individual tOo C ourprogram on discovery of novel neurotrophic factors.Prior experience in Frowth factor purification and char-actenzation is essential. Succesful candidate will partici-pate in hiring support staff. Sal and equity positioncommnnsurate with experience. Reply to: Cephalon,Inc, 145 B Pa , est Cheser, PA19380.

FACULTY POSlIIONS INCARDIOVASCULAR/RENAL

PHARMACOLOGYThe Departmnent of Pharmacology, University ofTen-

nessoc, Memphis, is seing candates for two tenure-track positions available immediately, in cardiovascular/renal pharmacology. Rank and salary will be commensu-rate with experience. Candidates should posscss a Ph.D.dgrein or related discipline, or anM.-D., and slsouldhave demonstrated excellence in re-search and commitment to tcadhino. Candidates shouldhave appropriate experience in application ofphysiokgy,biochemistry, molecular biology, or immunology to car-diovasclar/renal pharmacology. Candidates will be ex-peted tO participate in teaching of pharmacol tOprofessional and graduate sudents. Applicatons fromminority candidates and women are stngly encour-aged. Please submit curriculum vitae, the names othreerefernces, and a brief statement offuure rsearch plansto: Murray Heamberg, PhD., MD., Cairman, Dv-

ent of PhaJ olog, Universty of Tennesse,Memphis, The Healt Sence Ccnter, Memphis, TN38163. Search will continue until positions have beenfilled. The University of Tennessee is an Equal Opporunity/Afrnative Acion Employer.

MICROBIAL ECOLOGISTThe c ems Center of the Marine Bioogical Lab-

Oratory (MEL) is seeking applicants at the postdocralor masters leve for a National Science Foundationfiundd project. Research involves dissolvedo c mat-ter, bacteria and stable isotopes in estuanes. Applicantsshould have a strong background in chemistry, labora-tory research cxperience, and familiarity with field sam-pling techniques. Plcase submit curriculum vitae, state-ment of interests, and names of three refrences by 1August 1988 to: Dr. Bruc Petron, ECenter, MBL, Woods Hole, MA 023. A tivAction/Equal Opportnity Employer.

The Department of Pediatrics at the University ofMichigan is _wi aPEDIATRICGASTROENTER-OLOiIST. Dutics include adminisative responsibil-ite, paticnt carc, teaching and research activities. TheUniversity of Michigan is an Equal Opportunity/AfinnativeAction Employer. Ifintcrested please send curriculum vitaeto: A Craig H :ll , MD., Director, PediatricGtroen , C6105 OPB Box 0800, 1500 EastMcdial Center Drive, Ann Arbor, MI 48109-0718.

PHARMACOLOGIST/CELL PHYSIOLOGISTPATCH-CIAMP ELECTROPHYSIOLOGISTNatural Product Scicnces (NPS) Inc. is a rapidly-

grwing company involved in basic and applied researchon compounds of non-human biological origin. We areseeking two Ph.D.-leve scientists with expemse in cellphysiology/phar ology or electrophysioogy tO jOIn agroup Mvestigating the effects of such compounds. Ap-plicants for the ffrst position should have ecperiencestudying responses tO drugs in neural or cardiovasculartissues; the second position requires expcrience in patch-clamp analysis ofresponses in ncuronafor cardiovascularcells. Both positions offer the opportunityto work with awide range of nove compounds in an exciting andcomprehensive program involving pharmacology, chem-istry, and molecular biology. The successful applicantwill be given major responsibility for directng his or herown efforts and will be expected to contribute to evaluat-ing and guiding the general research pr rm. Qualifiedapplicants will also be eligible for facuity appontments inthe University ofUtah Department ofPhysiology, whichis adjacent to the companys facility. NPS offers competi-tive salaries and a full benefits package. Please send ar6sumi and the names ofthreernces to: Dr. HunterJackson, Natura Product Sciences In, 420 ChipetaWay, Sakt Lake City,UT 84108. Natural Produat SdeesInc. is an Equal Opportunity Employer.

IS JULY 1988

ONE DISCOVERYDESERVES ANOTHER

Boehringer Mannheim is a leader in Medical Diagnostics, Biochemicals,and Medical Research This leadership has been attained through

emphasis on quality and team effort. We are continuing our expansionand growth throughout 1988, and are seeking those talented individuals

lookino for a dynamic, Progressive organization which offers thepotential to turn aspirations into realitY

RESEARCH INVESTIGATORPROBE ASSAY DEVELOPMENT

We are seeking an experienced Senior Scientist or group leader for a

probe assay development project. The position requires a PhD., or

equilvalent degree, with 2 to 3 years of industrial experience in probeassay development with documentation of progressive increases in

_t- _ ___.----.TI :_. _ __.x___ ..__responsibility. inskills. The s

We aredevelopment proj

ie candidate must nave strong scientlric and supervisory

zuccessful applicant will supervise one of several groupsworking on a probe assay development project.

MANAGERPROBE ASSAY DEVELOPMENTseeking an experienced manager to head a probe assay

iect. The position requires a PhD., or equivalent degree,with 5 or more years of broad industrial experience in probe assay

development with documentation of progressive increases inresponsibility. The candidate must have strong leadership and

communication skills. ft will be necessary for the successful applicant to

put together a project team and to coordinate the team's efforts withcollaborating outside organizations.

At Boehringer Mannheim, we offer an exciting and challenqingenvironment as well as an eXcellent compensation and beneflt program.We invite you to send your resume with salary history, for confldential

consideration to: ept. SCI, HumRan Resources BOEHRINGERMANNHEIM, P.. Box 5G1t0, 9115 Hague Road, Indiewois IN 45250

We are an equal opportunity employer

BOEI1NGERMMNNHEIM

ag

.- -.. ...7 .1

RESEARCHANDDEVELOPMENTOPPORTUNITIES

The Dade Division of Fortune 75 Baxter HealthcareCorporation is a worldwide leader in the developmentand manufacture of clinical diagnostic products andinstrumentation. Through research and development,our reputation for quality products continues, creatingimmediate opportunities for scientists in our Research& Development operation. Current opportunitiesinclude:

ImmunochemistryResearch Scientist

This position requires working knowledge of variousimmunochemical techniques utilized in the analysisof monoclonal and polyclonal antibodies. The candi-date should possess a B.S. or M.S. in BiologicalScience and 3-5 years experience in a laboratoryenvironment. Familiarity with immunoassay, electro-phoretic and chromatographic techniques is desirable.

Immunology ResearchScientist

This position involves research, development, andproduction of monoclonal antibodies. A B.S. or M.S.in Biological Science or related field is desired, alongwith experience in sterile technique. The incumbentshould possess 3-5 years tissue culture experienceand prior work with animals in a laboratory setting.Working knowledge of GMP's highly desirable. Inaddition, qualified individual will possess good tech-nical skills in immunology and will be able to functionas a member of a team.

Research ScientistThis position, in our STRATUS Reagent Development

Department, involves performance of experiments andformulation of reagents to establish immunoassayfeasibility, stability, precision and accuracy. Either aB.S. or M.S. in Chemistry, Immunology or related fieldis required; industrial immunoassay development aplus. Good communication skills and computer expe-rience desirable.The Dade Division is based on the beautiful east

cost of south Florida where, in addition to paying nostate or local income taxes, you will enjoy a year-roundquality lifestyle which attracts new residents andvisitors from around the world. As a member of theBaxter R&D team, you will not only enjoy an outstand-ing professional and scientific environment and ex-ceptional career growth opportunity, you'll also receivea very competitive salary and benefits package.For consideration for any of the above positions, pleasesend your resume along with salary history in con-fidence to: Proesional Staffing, Baxter HealthcareCorporation, Dade Division, P.O. Box 140520,Coral Gables, FL 33114. Equal Opportunity Employer.

Dade Division

Baxter

THE UNIVERSITY OF ALABAMA

Position Announcement for

DIRECTOR, ENVIRONMENTAL INSTITUTE FORWASTE MANAGEMENT STUDIES

The University of Alabama invites applications and nominations for the position ofDirector of the Environmental Institute for Waste Management Studies (EIWMS). Theposition will carry an academic appointment either in the College of Engineering or theCollege of Arts and Sciences. The Director will report to the Academic Vice-Presidentand the academic department chairman. To be successful, a candidate is expected tohave a strong academic background with a record of research and publications in wastemanagement. An earned doctorate in engineering or science is required. Candidatesmust have demonstrated dynamic leadership, be a good motivator, possess goodadministrative skills, and have an interest in govemment interaction. Interviews willbegin on June 1, 1988. Applications will be considered until the position is filled.The Environmental Institute for Waste Management Studies was established in October1983 in recognition by The University of Alabama of the "need for an effective andcredible vehicle to study and inform the public, the media, and government officials ofthe major technical issues involving safe management of hazardous and non-hazardouswastes" (Charter of EIWMS). Patterned after the National Academy of Sciences panels,the Institute members are academicians from across the United States. They include ageologist, hydrogeologist, toxicologist, environmental socioeconomist, statistician,geochemist, biologist, and civil, chemical, biochemical, and geochemical engineers.During the past four years they have completed 19 major studies resulting in thepublication of intemally and externally reviewed open file reports. Funding for theInstitute is from industry, federal and state sources.The University of Alabama is a dynamic, sun-belt university located in Tuscaloosa,situated in the rolling hills of West Alabama about fifty miles southwest of Birmingham.The metropolitan area has a population of about 130,000. Most winters are snowless,and the region abounds with lakes and streams.

Applicants should send a resume which includes three references to:Dr. Irvin A. Jefcoat, ChairmanEIWMS Search CommitteeP.O. Box 6373Tuscaloosa, AL 35487-6373

The University of Alabama is an equal opportunity/affirmative action employer.

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-j

The John rvn NeumaNadona SpLaeLptter Center

VISUALIZATIONSCIENTIST

The John von Neumann National Supercom-puter Center (JvNC) in Princeton, New Jerseyis seeking candidates for the position of Visu-alization Sdentist. The JvNC is operated bythe Consortium for Scientific Computing, Inc.,a non-profit corporation formed to providestate-of-the-art supercomputer resources tothe national community of research sdentists,engineers and mathematidans.Responsiblities are: collaborates as a peer withsenior researchers from academia and industryin every sdentific and engineering discpline,using Visualization in Sdentific Computing torefine choices of algorithm instrument super-computer codes, and darify tradeoffs amongspecalized capabilities (e.g., interactMty versusrealism) between supercomputer and worksta-tion. Publishes (co) authored papers inreferred scientific journals and represents theCenter at SIGGRAPH and other professionalmeetings. Initiates research projects proactivelyand writes grant proposals.M.S. degree in the sciences and at least fiveyears direct experience in graphics and imageprocessing is required. Must have demon-strated dose collaboration on sophisticatedcomputational problems with senior sdentist inmore than one field. Excellent written andoral communication skills are required. Fluencyin FORTRAN and C is required and experiencewith scientific codes of at least 10,000 FOR-TRAN lines is preferred. A Ph.D. and experi-ence with advanced human interface designissues, particularly on interactive high-perform-ance workstations and supercomputers, isdesired.This grant funded position offers an excellentbenefits package and a salary commensuratewith experience. To apply, send resume, salaryhistory and salary requirements indicatingreference #408 to:

,HF STATE UNIVERSITV OF NEW JERSEY

Division of Personnel ServicesPiscataway, N.J 08855Successful candidate toprovide employmenteligibility verification

AA/E.O.EI I

M:ICROBIOLOGIST-IN-CHIEF

The Hospital for Sick Children, one of thelargest paediatric hospitals in North America,invites applications for the position ofMicrobiologist-in-Chief. Located in downtownToronto, the Hospital is in close proximity to,and affiliated with the University of Toronto.The Department of Microbiology is a newdepartment formed by the amalgamation ofBacteriology and Virology, each of which ishighly productive in service, research andteaching activities, and provides a clinicalconsultative service.The position is responsible for theadministration of a hospital laboratorydepartment with a combined professionalcomplement of 2 virologists, 3 medicalmicrobiologists and several researchscientists.There is an Infectious Disease Division of theDepartment of Paediatrics that collaborateswith the Department of Microbiology.Candidates should be medically qualifiedand possess specialist qualifications inmedical microbiology from the Royal Collegeof Physicians and Surgeons of Canada or anequivalent body. The incumbent should beexperienced in directing a microbiology servicelaboratory. It is expected that the applicantwill be active in research and teaching.Through the affiliation with the University ofToronto, the incumbent will be required toparticipate in teaching at undergraduate andpostgraduate levels, including residenttraining in medical microbiology and otherallied disciplines. Cross-appointments withthe University of Toronto, Department ofMicrobiology are customary at an appropriaterank, subject to the approval of the Professorand Chairman of Medical Microbiology.In accordance with immigration regulations,priority will be given to Canadian citizens andpermanent residentsofCanada.An applicationincluding curriculum vitae and appropriatereferences should be forwarded by August1, 1988, to: Chairman, Search Committee,Microbiologist-in-Chief, c/o Mr. BruceLaughton.

555 University AvenueToronto, Ontario M5G 1X8

IU

-I THE HOSPITALFOR SICK CHILDREN

POSITIONS OPEN

PARASITOLOGISTASSISTANT PROFESSOR

A 3-year, nontenure-trackJresearch faculty positionavailable fall 1988, for a helminthologist, with at least 2years of postdoctoral experience involving parasite bio-chemistry or genetics. Opporties exist for collabora-tive research in molecular biology with the interdisciplin-ary Microbiology Department at The University ofTen-nessee, Memphis and associated institutions. Send curric-ulum vitae, brief description of research interests, andnames of three references by 29 July 1988, to:

Dr. Raymond H. CypessDepartment of Microbiology & Immunology

The Ufniversity of Tennessee Health Scicnce Center847 Monroe Avenue, Room 217

Memphis, TN 38163The University of Tennessee, Memphis is an Equal Employ-

ment Opportunity/Affirmative Acion Employer.The Department of Pediatrics at the University of

Michigan is seeking a Board-eligible/certified PEDIA-TRICIAN. Duties indude patient care, teaching andresearch activities in the fields of general pediatrics orambulatory care. The University of Michigan is an EqualOpportunity/Afirmnative Action Employer. If interestedplease send curricula vitae to: Robert C. Kelsch, M.D.,Direcor, Pediatric Ambulatory Care, Department ofPediatrics, 1924 Taubman Center, UMMC, 1500East Medical Center Drive, Ann Arbor, MI 48109-0318.

PHYSICAL METALLURGIST: 40 hours perweek. 8:00 a.m. to 4:30 p.m., $44,990.40 per year.Responsible for the development of novel dagnosticmethods and finite element analysis for the study ofmechanical testing of small volume solid samples. Re-sponsibk for mechanical testing, particularly the impres-sion test methodologies as applied to weldments andsuperplastic alloys. Responsible for development of im-proved techniques for the manufacturing offerromagnet-ic amorphous alloys. Must possess a thorough under-standing of mechanical testing methods, with demon-strated practical experience in the study ofweldment andsuperplastic alloy. Knowledge of computer software re-quired. Ph.D. in materials science and 3 years of experi-encein physical metatlurgy rescarch required. S,ndr5su-me to: D ta¶entrfE rloyment Servicns,500 CStreet, Room 325, N.W.,Nashington, D.C. 20001.Telephonc: 202-724-3770, Monday to Friday, 9:30a.m. to 3:30 p.m. Indicate in resume Job Order # 5975.

POSTDOCTORAL ASSOCIATEA postdoctoral position is available to study either the

regulation of maternal mRNA expression in early Xeno-pus development [cf. Development 101, 741 (1987)] orthe mechanism of adenovirus ElA-induced transcriptionusing injected Xenopus oocytes [cf. Mol. Cell. Biol. 7,3049 (1987)]. Send curriculum vitae and three refer-ences to: Dr. Joel Richter, c/o Personnel Office,Worcester Foundation for Experimental Biology,222 Maple Avenue, Shrewsbury, MA 01545.An Equal Opportunity/Afirmative Action Employer M/F/H.

University of Michigan: Unexpected immediate op-portunity for POSTDOCTORAL FELLOW with syn-thetic or organometallic chemistry background to reineradiometal labeling of monoclonal antibodies. Well-equipped laboratory with multidisciplinary environment.Ideal position for the chemist desiring to apply chemicalsolutions to biological systems. Position is NIH-fundedand applicants must be U.S. citizen or permanent resi-dent. Please send curriculum vitae with name of tworeferences to: Richard L. Wahl, M.D., Division ofNudear Medicnc, Univcrsity of Michigan MedicalCenter, jAnn Arbor, MI 48109-0028. The University ofMichigan is a non-discriminatory, Affirmative Action Employer.

POSTDOCTORAL POSMIIONPostdoctoral position is available immediately to study

gene expression in preimplantation mouse embryos. Weare using in situ hybridization of gene-specific probes toexamine the relationship between gene expression andcell lineage in the early embryo. Backgund in molecularbiology or embryology wouid be useful. Send curriculumvitae to: Dr. William Crain, c/o Personnel Office,Worcester Foundation for Experimcntal Biology,222 Maple Avenue, Shrewsbury, MA 01545.An Equal Opportunity/Affirmative Aaion Employer M/F/H.

382

I IThe COMMISSION ON LIFESCIENCES of the National ResearchCouncil seeks a Director to administerits Board on Biology - an ongoing pro-gram of studies in biology. The positionrequires broad experience and expertisein areas ranging from ecology to geneticsand neuroscience. Applicant should haveat least 6 years of experience in theacademic or government environment,preferably a combination of both, and arecord of holding increasingly responsi-ble positions involving the examinationof issues requiring knowledge of biologyand science policy issues, e.g., scienceeducation, research resources, andresearch trends. A doctorate or equiva-lent in one of the life sciences isrequired, along with demonstrated skillsin communication, administration, andinterpersonal relations.The NRC offers a salary commensuratewith experience and an exceptionalbenefits package including paid reloca-tion to the D.C. area. Please sendcurriculum vitae and letter of interestin confidence to:COMMISSION ON LIFE SCIENCESJ. Burris/NAS 3432101 Constitution Ave., N.W.Washington, D.C. 20418 NASAn Equal Opportunity IOAMEmployer.

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Genentech, Inc., a leader in thefield of biotechnology, is currentlyseeking an Associate Scientist towork with our Immunopharmacol-ogy Group pursuing research anddevelopment of experimental animalmodels and in vitro assays for eval-uating the immunogenicity ofrecombinant proteins.Requirements include 2 + years ofpostdoctoral training in immunologyand a demonstrated, strong back-ground and interest in investigatingimmunobiological effects of anti-genic structure and antigen process-ing, B and T cell epitope mapping,T cell cloning and cellular immuneresponsiveness to peptide and pro-tein antigens, and/or immunogene-tic. Experience with in vitro and invivo immunological assays in

The NATIONAL RESEARCH COUNCILis seeking an Associate Director for itsSoviet and East European Affairs Office.The incumbent will share with the Directorresponsibility for managing a program ofexchanges of scientists, bilateral scientificworkshops, cooperative research pro-grams, and science policy studies. Otherresponsibilities include supervision ofspecial cases, scientific leadership forstructuring workshops, and providing ad-vice on programs concerning U.S. scientificrelations with the USSR and EasternEurope. Requirements include a minimumof five years' experience in administeringscientific programs with significant inter-national components; MS or Ph.D. inscience or engineering; knowledge of scien-tific and economic developments in theUSSR and Eastern Europe, internationalscience policy issues, and East-Westeconomic and technological security issues.Proficiency in Russian language desirable,but not required. Excellent written and oralcommunication skills necessary. Salaryrange: $50-60,000. The Academy offers anexcellent benefits package including paidrelocation to the D.C. area. Please sendresume in confidence to: NATIONALRESEARCH COUNCIL,SEEA/AD/HA 166, ENA92101 Constitution Ave., N.W., *NAEWashington, D.C. 20418. EOE. IQM

murine models is also essential.Some knowledge of human immuneassays would be helpful.Genentech, Inc. offers an excellentsalary and benefits package coupledwith the opportunity to make a sig-nificant contribution to our organi-zation. For consideration, pleasesend your resume to Eric Mankuta,Human Resources Department 557,Genentech, Inc., 460 Point SanBruno Blvd., South San Francisco,CA 94080. An equal opportunityemployer.

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ScientistImmunopharmacology

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DEVELOPMENTALNEUROBIOLOGISTThe Hospital for Sick Children Research Institute,one of the largest and most active of its kind in theworld, is seeking an outstanding scientist with aPh.D. or M.D. to carry out basic research indevelopmental neurobiology as related to cardio-respiratory control. The appointee will have theopportunity to interact with an established groupstudying the sudden infant death syndrome whiledeveloping his/her own research program. Theposition is well funded, and includes both on-going support and a salary, which is negotiable.The appointment will be at a rank commensuratewith experience and background, and will includeappointment to the senior staff of The ResearchInstitute.Send curriculum vitae, a brief description of researchinterests, and the name of three references beforeAugust 15,1988, to: Dr. Barry T. Smith, TheResearch Institute.

555 University Avenue'-'2 Toronto, Ontario M5G 1X8

II THE HOSPITALFOR SICK CHILDREN

PUBLIC HEALTH SERVICE, NATIONAL INSTITUTES OF HEALTHNATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES

RESEARCH TRIANGLE PARK, NORTH CAROLINADIRECTOR, DIVISION OF INTRAMURAL RESEARCH

A SENIOR EXECUTIVE SERVICE VACANCYThe National Institute of Environmental Hiences (NIEHS) invites nominations andtions for the position of Director, Division olral Research. This is a Civil Service positSenior Executive Service (SES) with a salof $65,994 to $73,400 per annum. In addicandidates may be eligible for a Physiciaparability Allowance up to $20,000 per yenatively, candidates may be eligible for ap,in the Commissioned Corps of the U.'Health Service.) A one-year probationamust be served if the individual selectcurrently in the SES.The Division of Intramural Research p

conducts the Institute's basic laboratoryprograms which encompass the areas cand molecular pharmacology, genetics, rbiophysics, molecular carcinogenesis, rgenetics, molecular and integrative neuro'pulmonary pathobiology, reproductive aropmental toxicology and an animal facilityAs Director for the Division of Intrarr

search, the incumbent manages and dire(of approximately 397 employees and m;budget of approximately $17.5 million. DIFposed of eight laboratories and a branch ccbench research in-house and by contfincumbent evaluates research efforts arlishes Programs' priorities; allocates fundand personnel ceilings and integrates ongnew research activities into Programs'collaborates with other organizations, andgrams; and provides advice to the Institutiand staff on matters of scientific interenational expert in the field of environmenlthe incumbent serves as expert consultEthe United States and abroad.

ealth Sci- Candidates must meet the following professional prioritiesIapplica- and managerial qualifications: ability toIfntramu- Mandatory Qualification Requirements through ation in the This is a multidisciplinary position. All candidates ing skills;ary range must: (1) meet the minimum educational require- subordin;ition, M.D. ments for either; (a) Biologist, GS-401, (b) Chemist, attitude rkn's Com- GS-1 320, (c) Medical Officer, GS-602, (d) Pharma- opportunar. (Alter- cologist, GS-405, (e) Microbiologist, GS-402, (f) organizalpointment Physiologist, GS-413, or (g) Geneticist, GS-440, as governmfS. Public described in the U.S. Office of Personnel Manage- communiry period ment Handbook X-1 18 (Qualification Standards for ganizatioed is not Positions under the General Schedule) which is and (6) t

available in Federal Job Information Centers and evaluatioc)lans and Federal Personnel Offices; and (2) Biomedical re- Candidresearch search experience at the GS/GM-1 5 grade level or tions will)f cellular equivalent which reflects demonstrated abilities to tors: trairmolecular develop, implement and administer intramural re- andleademolecular search programs using the muftidisciplinary re- environrrsciences, search approaches to environmental health; con- recogniti(nd devel- siderable experience involving research, analysis managere. and evaluation of data related to the study of biologi- mandatoiiural Re- cal and hazardous effects of chemical, physical and Furthercts a staff biological substances found in the environment. cation reanages a Mandatory Managerial/Executive Bruce WR is com- Qualifications ment Spi)nducting The incumbent must have had extensive expe- is requireract. The rience of sufficient scope to carry outthe managerial Resumid estab- duties of the position. Experience must have in- entranceIs, space, cluded progressively responsible experience in di- cations, '3oing and recting, guiding and managing complex research mation Cstructure; projects and/or programs. Must have demonstrated accompaINIH pro- possession of: (1) a broad knowledge of and demon- bibliograle Director strated ability to apply management practices and August 1ast. As a principles related to planning, organizing, staffing, Brucetal health, directing, allocation of resources and coordinating NIEHSant within complex research programs; (2) ability to develop P.O. B(

policy and establish short-term and long-term goals, ReseaiNIH IS AN EQUAL OPPORTUNITY EMPLOYER

and objectives for complex programs; (3)deal with diverse and complex problemsapplication of analytical and decision-mak-(4) ability to select, develop and utilize a

late staff, including a demonstrated positiveregarding the implementation of an equality program; (5) ability to represent theition and deal effectively with high leveliental officials, the scientific and academicities, national/international professional or-ns and societies and the general public;skill and ability to conduct analysis and)n of programs.dates who meet the mandatory qualifica-Ibe further evaluated on the following fac-ning and education; research experienceership of a research program in or related tonental health; scientific reputation/peerion; honors and awards; and additionalrial/executive qualifications in excess of theiry level.,r information about the position and qualifi-quirements may be obtained by callingViggins, Supervisory Personnel Manage-ecialist at 919-541-3317. U.S. Citizenship3d.nes are not acceptable applications forinto the Senior Executive Service. Appli-SF-1 71 (available at all Federal Job Infor-Centers and Federal Personnel Offices)anied by a current curriculum vitae andphy should be submitted not later than9, 1 988 to:Wiggins (Code: HNV2)Personnel Officeox 12233rch Triangle Park, NC 27709

THE

SCiENCERECRUITMENT

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FOUR DAYS AFTER SUBMISSIONScientific Recruiters can now advertise positions almost assoon as the need arises. Instead of reserving space a month ormore in advance, you can now place your ad four days beforethe magazine mailing date. SCiENCE is mailed on the cover date.Film (right-reading, emulsion face down) or full camera readyart and insertion order must reach: StCiENCE, Short Close Desk,1515 Broadway, New York, NY 10036 by NOON Mondays(except for legal holidays when material must reach New Yorkby Noon Fridays). Because space is limited, the four-day closepage will be reserved on a first-come, first-served basis, at a15% premium. 1/4 and 1/2 page ads only.Now you don't have to wait to find the researchers you needimmediately, nor must you advertise in a Sunday paper thatpans a lot of sand, but not much gold. Scientific employersknow that SCiENCE ads fill the job better. Now they fill it fastertoo.You can call it "INSTANT RECRUITMENT."For further information, telephone Ed. Keller, Recruitment Ad-vertising Manager, or Donna Rivera, Production Manager atSCiENCE: 212-730-1050, or write to: SCiENCE, 1515 Broadway,NY, NY 10036.

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aI

POSITIONS OPEN

PLANT VIROLOGISTKansas State University, Department of Plant Patholo-

gy, invites applications for a tenure-track position at theassistant professor level to begin 1 October 1988. Suc-cessful candidate will be expected to investigate themolecular basis of viral biology and disease and partici-pate in the development of control measures for impor-tant viral diseases of cereal crops. A Ph.D. in plantpathology and a strong record of training and researchexperience in plant virology is required. Salary commnen-surate with academic training and experience. Submitletter of application, resume, transcripts, and three lettersof reference to: Dr. Frank F. White, Department ofPlant Pathology, Throckmorton Hall, Kansas StateUniversity, Manhattan, KS 66506 bv 1 September1988. Kansas State University is an Equal Opportunity!Afirmative Action Employer.

POSTDOCTORAL FELLOW/RESEARCH AS-SOCIATE. Work in the area of intestinal development,adaptation and gene-nutrient interaction, including isola-tion of cDNA and genomic sequences encoding theamidophosphoribosvl transferase gene. Experience withcDNA cloning and sequencing as well as general knowl-edge of molecular biologv desired. Send curriculum vitaeto: Neal S. LeLeiko, M.D., Ph.D., Department ofPediatrics, The Mount Sinai School of Medicine, Box1198, One Gustave L. Levy Place, New York, NY10029-6574. Ani Equal Opportunity Employer.

POSTDOCTORAL POSITION available immedi-ately in the Pacific Northwest to studv regulation andexpression of tyrosine protein kinases and phosphotvro-syl phosphatases. The applicant will investigate the regu-lation of the kinase activities of receptors bv phosphoryl-ation and dephosphorvlation using a varietv of differentmolecular techniques. The individual should possessstrong research skUs with a background in proteinchemistry, enzymology, or molecular biology and haveobtained a Ph.D. within the last 4 vears. Send curriculumvitae and names of three references to: Dr. G. M.Clinton, Dtpartnent of Biochemistry, Oregon HealthSciences Umversity, Portland, OR 97201. OHSU is anEqual Opportunity/Affirmative Action Employer.

POSTDOCTORAL POSITION in molecular de-velopmental genetics available fall/winter, 1988 in theBiology Division of the Oak Ridge National Laboratory.Project involves the molecular and functional character-ization of regions of the mouse genome associated withradiation-induced deletion mutations. Background ingenetics, molecular biology, and/or developmental biolo-gy desirable. Applicants should arrange for curriculumvitae, a brief statement of research interests, and threeletters of reference to be sent to: Dr. Eugene M.Rinchik, University of Tennessee-Oak Ridge Gradu-ate School of Biomedical Sciences, P.O. Box 2009,Oak Ridge, TN 37831-8077. An Equal Opportunity!Affirmative Action Employer.

POSTDOCTORAL POSITION available immedi-ately for a Ph.D. in biophysics/biochemistry or physicalchemist to participate in studies using NMR methodsto elucidate iomacromolecules solution structure andfunction. Specific systems include metalloproteins anddrug-protein interactions. Applicants must have provenexperience in NMR with experience in computer pro-gramming and protein manipulation techniques pre-ferred but not essential. Send curriculum vitae and thenames of three references to:

Dr. Ian M. ArmnitageYale University

Department of Molecular Biophysicsand Biochemistry

333 Cedar Street, P.O. Box 3333New Haven, CT 06510

POSTDOCTORAL POSITIONS-Research he-matology: The Hematology Division of the Johns Hop-kins University School of Medicine has positions avail-able now for individuals with an M.D. or Ph.D. degreeand an interest in hematology research (normal andneoplastic cell proliferation, coagulation, immunohema-tology, membrane proteins, genetic control of globinsynthesis, oxygen transport, red cell enzymes). U.S.citizenship required. Send curriculum vitae and three refer-ences to: J. L. Spivak, M.D., Hematology Division,The Johns Hopkins Hospital, Baltimore, MD 21205.Equal Opportunity/Affirmative Action Employer.

POSITIONS OPEN

POSTDOCTORAL POSITION available on 1 Julv1988 for beginning postdoctoral candidate. Position willbe in laboratorv studying epithelial cell polarity andmembrane protein sorting-research will involve analysisof targeting in epithelial cells transfected with genesencoding ion pump proteins-experience in molecularbiology is desirable. Position is funded by a departmentalNIH training-grant. Applicants must be U.S. citizens. Sendcurriculum vitae with names of references to:

Dr. Michael CaplanDepartment of Cellular and Molecular Physiology

Yale University School of MedicineP.O. Box 3333

New Haven, CT 06510

POSTDOCTORAL POSITION in molecular biol-ogy of drug metabolizing enzymes at the NationalInstitute of Child Health and Human Development,National Institutes of Health, Public Health Service, tostudy the genetics, regulation, and expression of glucur-onidating enzymes using biochemical and recombinantDNA techniques. Experience desired, but not required.Salary depends on experience and qualifications. Pleaserespond bv 26 August 1988. For further informationcontact: Dr. Ida S. Owens, Section on Drug Biotrans-fornation, Building 10, Room 8C313, National In-stitutes of Health, 9000 Rockville Pike, Bethesda,MD 20892. NIH is an Equal Opportuntity Employer.

POSTDOCTORAL POSITION available immedi-ately to study DNA damage and repair in higher cells.Experience in 32P-postlabeling, TLC, HPLC and massspectrometry desirable. Competitive salarv, plus fringes,based on experience. Please send curriculum vitae andnames of three references to: James W. Gaubatz, Ph.D.,Department of Biochemistry, College of Medicine,Umversity of South Alabama, Mobile, AL 36688. AnAffirmative Action/Equal Opportunity Employer.

POSTDOCTORAL POSITION available to studymuscle fiber types-development and neuronal regula-tion of myosin expression; methods include immunocy-tochemistry and electron microscopv. Background inmuscle biology desirable. Send curriculum vitae andnames of three references to: Dr. G. F. Gauthier,Department of Cell Biology, University ofMassachu-setts Medical School, 55 Lake Avenue North,Worcester, MA 01655. UMMC is an Equal Opportunity!Affirmative Action Employer.

POSTDOCTORAL POSITION IN HORMONERECEPTORMOLECULAR BIOLOGYAND BIO-CHEMISTRY. Parathvroid hormone isolation, charac-terization, sequencing, and molecular biology. Immnedi-ate opening for beginning postdoctoral candidates. Ex-cellent salarv and fringe benefits. Stimulating intellectualenvironment in a basic science department. Call or applydirectly to: J. E. Zull, Department of Biology, CaseWestern Reserve University, Cleveland, OH 44106.Telephone: 216-368-3572. CWRU is an Equal Opportu-nity/Afirmative Action Employer.

POSTDOCTORAL POSITION IN IMMUNO-GENETICS/AUTOIMMUNE DISEASE. Strongmolecular genetics background required, salary negotia-ble. Position includes appointment as research fellow atthe Universitv of Wisconsin.

Principal projected studies in the laboratorv includefurther characterization of the HLA and T-cell receptorgenes that affect susceptibilitv to insulin-dependent dia-betes. We are currently investigating these genes andtheir products at the cell-surface and DNA levels, andwill extend the investigation to the whole-bodv level in atransgenic mouse study with the assistance of the Univer-sitv of Wisconsin Biotechnology Center.

Please send curriculum vitae, one page or less describ-ing your research experience, and three reference lettersto: Michael Sheehy, Ph.D., Science Director, Ameri-can Red Cross Blood Center, 4860 Sheboygan Ave-nue, Madison, WI 53705.

POSTDOCTORAL POSITIONS in microbial ecol-ogy/biogeochemistry available September 1988 in theareas of bacterial decomposition, organic matter transfor-mations, and fate of novel genetic sequences in marineand freshwater ecosvstems. Please send curriculum vitaeand names of three references to: Dr. Robert E. Hod-son, Department of Microbiology, University ofGeorgia, Athens, GA 30602. An Equal EmploymentOpportunity/Afirmative Action Institution.

POSITIONS OPEN

POSTDOCTORAL RESEARCH ASSOCIATEDAVID TAYLOR RESEARCH CENTER

Annapolis, Maryland 21402-5067Fall 1988. To study marine microbial attachment

mechanisms. Experience in microbiology, spectral meth-ods, surface characterization desirabke. Contact: Dr.Loeb at 301-267-2460. An Equal Opportunity Employer,U.S. citizenship required.

POSTDOCTORAL RESEARCH SCIENTISTMOLECULAR AND DEVELOPMENTAL

NEUROBIOLOGYPostdoctoral scientist position available as of the fall of

1988 to study gene regulation during the developmentof neurons. Ongoing efforts include the identification ofgenes related to neuronal differentiation and plasticity,the study of their transcriptional control, and the analysisof their function by purturbation in vitro and in trans-genic mice.

Interested persons should send curriculum vitae to:Dr. Mark C. Fishman

Howard Hughes Medical InstituteWellman 4

Massachusetts General HospitalBoston, MA 02114

RADIOBIOLOGISTThe Department of Radiation Oncology at the Uni-

versity of North Carolina is recruiting at the assistantprofessor level for a radiobiologist. The candidate willave completed a Ph.D. in radiobiology and have experi-

ence in the study of cellular systems, tumor biology, andtumor response to radiation and radiation modifyingagents. Women and minorities are encouraged to identiXthemselves voluntarily. UNC is an Equal Opportunity/Afir-mative Action Employer. Send a current curriculum vitaeby 31 August 1988 to: Joel Tepper, M.D., Departmentof Radiation Oncology, North Carolina MemorialHospital, Chapel Hill, NC 27514.

RESEARCH ASSISTANT PROFESSOR, medicalbiochemistry. Twelve-month, renewable. Research onlipid peroxidation in human degenerative disease usingGC-MS. Teach biochemistry and biochemical basis ofhuman disease states to medical students. Ph.D. inbiochemistry or related area, research experience in GC-MS, and strong publication record required. Experiencewith human biopsy methods and an M.D. desirable.Salary $30,000 to $40,000, dependent on qualifications.Desired start date 1 September 1988. Screening begins 1August 1988. Send letter of application, curriculumvitae, and three letters of recommendation to: EdwardA. Dratz, Professor of Chemistry, Montana StateUniversity, Bozeman, MT 59717. MSU is an EqualOpportunity/Afirmative Action Employer.RESEARCH ASSISTANT PROFESSOR with 5

years of postdoctoral training to study flavonoids in cellactivation and chemoprevention. Ph.D. biochemistry/enzymolo trainng in polyphenol metabolism. Experi-ence in ce an or anele isolation, membrane enzymesand purification/characterization, lipid peroxidation,HPLC, enzyme induction/xenobiotic metabolism, car-cinogen-DNA binding, carcinogen metabolite character-ization, radioisotope handling and write grant proposals.Candidate expected to develop independent researchprogram on flavonoids. Salary: to $27,500. Send resumeand three reference letters to: Director, Allergy Divi-sion, SUNY/Buffalo, Buffalo General Hospital, 100High Street, Buffalo, NY 14203. Affirmative Action!Equal Opportunity Employer.

RESEARCH ASSOCIATECORNELL UNIVERSITYMEDICAL COLLEGE

The Laboratory of Psychopharmacology, Cornell Uni-versity Medical College seeks applicants to work on aprogram studying monoamine receptor regulation andrelated areas in human brain and peripheral tissues.Applicants must have a Ph.D. and postdoctoral experi-ence in biochemistry/molecular biology/pharmacology.Experience with receptor binding, autoradiography andHPLC would be an advantage. A supervisory role isavailable for a suitable experienced applicant. Send cur-riculum vitae and names of three references to: Dr. JohnMann, Departnent of Psychiatry, Cornell UniversityMedical College, 1300 York Avenue, New York, NY10021. Equal Employment Opportunity/Affirmative Action!MIFIHIV.

SCIENCE, VOL. 241384.

POSITIONS OPEN

PROFESSOR AND HEADPENN STATE DEPARTMENT

OF ENTOMOLOGYApplications and nominations are invited for this

position which is the departmental administrative officerand program leader, and reports directly to the Dean ofthe Colege of Agriculture. Qualifications include aPh.D. in entomology or closely related field, and asignificant period of professional or academic experiencewith a strong record of scholarly activities. The applicantshould have an understanding ofthe land-grant universi-ty system. Letter of application should include completeresume with documentation of academic training andprofessional leadership. Names, addresses, and telephonenumbers of five individuals who can be contacted forrecommendations should be included. Applications willbe accepted through 15 August 1988, or until a suitablecanddidate is identified. Nominations and letters ofapplication should be forwarded to: Dr. Arthur A.Hower, Chairman ofSearch Committee, DepartmentofEntomology, 106B Patterson Building, Penn StateUniversity, UIniversity Park, PA 16802. Penn State is anAfirmative Action/Equal Opportunity Employer. Women andMinorities are encouraged to apply.

THEMAX-PLANCK-GESELLSCHAFT

OPENS AT THEMAX-PLANCK-INSTITUT FURIMMUNBIOLOGIE, FREIBURG

THE"HANS-SPEMANN-LABORATORIES"

In the new building several independent research gupsare to complement and extend the permanent research areasof the institute which indude: Cellular immunology, mo-kcular immunology, biology of infectious and parasiticdiseases, bacteriology and embryology.We are looking for internationally recognized young

scientists asRESEARCH GROUP LEADERS

working in the above mentioned fields or in tumorbiology, cell biology, protein chemistry, gene regulationand differentiation in vertebrates.The duration of the contract starting at the earliest in

June 1989 will be 5 years with a salary in accordance withqualification up to approximately DM 73,000, per an-num (C3 of the German University scale, equivalent toassociate professor). There is no teaching commitment.The groups will have modern laboratory facilities with

up to 120 m of laboratory space, operating expenses andfunding for scientific and technical co-workers.

Applications, including a tabular curriculum vitae, listof publications, and a description of major scientificachievements and future research plans, should be sub-mitted by 31 August 1988 to:

Dr. Georges KohlerGeschiiftsfihrender Direktor

des Max-Planck-Instituts fir ImmunbiologiePostfach 1169

D-7800 Freiburg i.Br.

DEPARTMENT OF NEUROBIOLOGY,ANATOMY AND CELL SCIENCEUNIVERSITY OF PrITSBURGH,

SCHOOL OF MEDICINEWe are seeking to fill THREE TENURE-TRACK

POSMIIONS with individuals having research intereststhat are compatible with current areas of strength in thedepartment. These include neural development, nerve-muscle interactions, neural transplantation, cortical orga-nization, endocytotic mechanisms and cell/cell interac-tions. Techniques used include molecular biology, anti-body probes and cell biological approaches as well asmore traditional neurophysiological and neuroanatomi-cal methods. Candidates must have strong competitiveresearch programs, and be prepared to teach in medicalhistology/cell biology or gross anatomy courses as well asparticipate in interdisciplinary graduate programs. Dead-line for application is 30 September 1988.

Please send curriculum vitae, a summary of currentresearch and future research plans and the names of threereferences to: Raymond D. Lund, Chairnan of SearchCommittee, Department of Neurobiology, Anatomyand Celi Science, University of PittsburIO, School of'Medicine, Pittsburgh, PA 15261. The University is anEqual Opportunity/Affirmative Action Employer.

15 JULY I988

--.

Molecular Diagnostics, Inc. (MDI). Molecular Therapeutics.Inc. (MTI). the Institute for Arthritis and Autoimmunity(IAA). and Miles Institute for Preclinical Pharmacology(MlPP) are advanced research institutes which collectivelycomprise the newly-formed Miles Research Center in WestHaven. CT. The Center functions as a major researchresource of Bayer AG of West Germany and its subsidiary.Miles Inc. It is located in a newly-constructed facility whichis the first of several such facilities to be built at the WestHaven site.

MDI and MTI are engaged in biotechnology research; thenewly-formed IAA is dedicated to the discovery of new tar-gets for drug therapy. Areas of interest include molecularand cellular genetics, nucleic acid chemistry, cell biology,immunology and protein chemistry. The individual insti-tutes function collaboratively with each other, and withother research entities of the Bayer group.

I--r--

RESEARCH ASSOCIATESApplicants must have BS or MS degree, 1 year or more experience, and

proficiency in any of the following areas: RNA isolation and recombi-

nant DNA techniques; nucleic acid hybridization; protein biochernistry:tissue culture or hybridoma technology.

The companies are located in a new research facility near New Haven

and Yale University, and midway between Boston and New York

City. They offer competitive salaries, excellent benefits, and a stimu-

lating and challenging work environment.

Applicants should forward a curriculum vitae along with a state-

ment of research interest and capabilities in confidence to: Research

Director. Molecular Diagnostics, Inc., 400 Morgan Lane. West Haven.CT 06516.

An Equal Opportunity Employer M/F/H/V

PERSONNEL PLACEMENT 385

POSITIONS OPEN

RESEABCH ASSOCIATE: Postdoctoral positionto study the role of atmospheric nitrogen deposition innitrogen concentrations and acidification of drainagewaters. Strong background in biogeochemistry, dataanalysis, conputernodeIing and statistics reauired, as well

cs&udronduct independct research.Submit curriculum vitae and three letters of refrence to:Dr. Chares T. Drisooll, Deament of Civil Engineer-ing, 220 Hinds Hal, Syracuse Unirsity, Syracuse, NY13244 by 15 August 1988. Syracuse University is an EqualOpportunity/Afimative Action Employer.

RESEARCH ASSOCIATEINHALATION TOXICOLOGY

CIIT, an innovative leader in toxicology rcsearchsecks to fill the position of research associate in itsResearch Triangle TPark, North Carolina facility. Selectedindividual must have previous inhalation toxicologycxperience and will be responsible for generation andanalysis ofgas, vapor, and aerosol test atmospheres usinggas chromatography, IR-UV-VIS spectrophotometry,and wet chemical assays in conjunction with airbornesampling techniques. Experience in statistics and com-puter-based data management systems would bc benefi-cial. Requires good mechanical ability and M.S. or B.S.in chemistry or biology with 3 to 8 years of relevantexpeience. Reply in confidence to: Employment Of-fice, Chemical Indu;try Institute ofToxicology, P.O.Box 12137, Research Triangle Park, NC 27709. AnEqual Opportunity/Afirmative Action Employer.RESEARCH SCIENTIST for pharmaccutical man-

ufacturer in Central Ohio. Design and conduct researchnd deveopment in the area oftransdermal drug deliverysystems incudin skin permeation studies using chroma-tography and radiosstopes and prototype development.Evaluate physicochemical properties of drugs & ionexchange resins for preformulation and formuhlation ofcontroled release dosage forms, specialy transdermaldelivery sytems. Prepare technical progress reports onfindings. o experence necessary. Requires a Ph.D. inpharmaceutics with specialization in controlled releasetransdenral drug delivery systems. Must have one courseeach in: Drug diffusion; statistical analysis systems(SAS); animal. research methods; advanced physicalpharmacy; chromatography. Must be certified to handleradioisotopes in Ohio. Forty hours per week, 8 a.m. to4:30 p.m., $38,004 per year. Qualified applicants replyimmately wit resume to: A. Mac Lean JO#3045491, Ohio Bureau of Employment Services,P.O. BoX 1618, Colubus, OH 43216.

SCIENTIC PROGRAMMER/ANALYSTGeneral Servces Corporation (GSC), ranked as one of

the nationWs TOP 100 Small Companies, seeks scientificprogrammers and analysts for our current involvemcnt insoftware development for USEPA. Projects include: database management; data integration; uscr interface sys-tems development; and mapping and graphics related toenvironmental data.Prferred skills indude wfllingness to solve complex

problems, knowledge ofDBMS systems, PIU, and ISPFI man IBM 3090 MVS/XA environment. Company offerscompetitive salaries, advancement oprtumties, chal-knging work, and a completelbeneflts package. Pleaseforward your r6suni in confidence to Pamela McLean:

GSC6100 Chevy Chase Drive

Laurel, MD 20707'SOIL BIOGEOCHEMIST

Design and develop an ecologically-oricnted soil sci-ence tesearch p egramemphasizing gcosphere-bio--sph-ere&atmnosphere ist4racions for the Biological Sci-ences Center of the Desert Research Institute. Grantsupp and start-up funds are, available.

Reluirements include a Ph.D. in soil science, extensivetraining in the plant sciences, professional cxperienceteondt Ph.D., a strong pubiication record, and the

proven ability to attract research funding. A research-background emphasizing soil-plant-atmospherc interac-,-tions and/or remote sensing is highly desirable.

Salary cionimqisurate with jualifications, excellentbenefits. ApplicatiOns must be received by 19 August1988& Send turriulum vitac, statement ofiesearch inter-ests, and names of.three rfernces to: Personnel Office,DesertRscarth-jstitute, P.O. Box 60220, Reno,NV 8i66. For addtional information contact: Dr.Carl Fox atX702-673-7322.

An. Afinnative Action/Equal Opportunity Employer.

386

SENIOR STAFF SCIENTIST, National Biomedi-cal ESR Center. A position is available for an individualwith a Ph.D. in biophysics with cxperience in pulseelectron spin resonance spectroscopy. Our funded 9IHgrant emphasizes saturation recovery experiments onsynthetic and biological mcmbranes. Salary: $25,000.Rsuns to: Dr. James S. Hyde, Director, NaionalBkxnedical ESR Cetr, Medical College ofWiscmsin,8701 Watrtown Plank Road, M ihwauee, WI 53226.Equal Opportunity, Affirmative Action Employer M/F/H.

TOXICOLOGIST/ELECTRON MICROSCO-PIST RESEARCH SCIENTIST. The Virginia Insti-tute of Marine Science (VIMS), School of Marine Sci-ence, College of William and Mary, is seeking a Ph.D.-level scientist with a background in toxicology andelcttron microscopy. The applicant will conduct rcsearchon the efects of toxic chemicals on marine or anisms atthe EM level and will direct the efforts ofthe EM facility.Women and minority scientists are encouraged to apply. Sendthree refcrencesand curriculum vitae by 29 July 1988 to:Professor E. M. Burreson, Search Committee, VIMS,Gloucestr Poiint, VA 23062. Equal Opportunity/Afir-mative Action Employer.

VIROLOGISTHands-on bench position working with HIV and

other viruses. Research involves quantitating the destruc-tion of infectious virus by chemical disinfction. GoodIndustrial opportunity. Salary is $30,000 to $40,000(commensufatc with experience). Send a detailed r6sumEw#h a letter of application to: Microgen, Inc., 122Farid Road, Fairfidd, NJ 07006.

AWARDS

The Rosenstiel School of Marine and AtnosphericSciaente ofthe University ofMiami secks nominations forthe ROSENSTIEL AWARD.The Rosenstiel Award is presented annually to recog-

nize outstanding achievemcnt and distinction in oceano-graphic scicnce. This year's award will be presented forexcellence in the field ofmarne geology and geophysicsNominations induding a curriculum vitae an the namesof duree referees should bc sent to: Dr. Garrett W.Brass, Chairman, Rosenstiel Award Committee, Di-vision of Marine Geolo and Geophysics, 4600Ricnbacker Caseway, L3149.

CALL FOR PAPERS

WASTE MINIMIZATION AND CLEANTECHNOLOGY: MOVING TOWARD THE 21STCENTURY. Abstracts are sought for this internationalconference to be held 29 May to 2 June 1989 in Geneva,Switzerland. Topics indude: Intemational Appraisals ofWaste Minimization Efforts; R&D Needs; ManagementDirections and Challenges; Training and Education;Industry-Specific Systems Approaches; and EmployeeIncentives. Major sponsors: U.S. EPA, InternationalSolid--Wastes and Public Cleansing Association. Sendabstracts by 31 July 1988 to: Dr. Arthur H. Purcell,Reur Policy Institute, PO Box 39185, Washing-ton, DC 20016.

FELLOWSHIPS

Univcrsity of Michigan: POSTDOCTORAL FEL-LOWSHIP availablc for rocent Ph.D. or M.D., Ph.D. inimmunology or relevant related field with expertse inimmunoglobuin genetics and protein cxpression. Specif-ic project involves doning, modil6ring and expressingDNA for a murmnc monoclonal antiby with high-levelreactivitv with man carcinomas, for eventual targtedcancer th p Muti-disciplinary laboratory with sup-port available at various levels for the proposed work.For M.D. applicants, program may be tailored to allowfor cventualboard certification In nudear medicine.Opportunity grcatest for the ventiuresome. Please sendcurriculum vitae and names of two refrences to: Rich-ard L. Wahl, M.D, Division of Nudear Medicine,University of Michigan -Medical Cnter, Ann Arbor,AM 4319-0028. Applicants must be U.S. citizen orpermanent resident. The University of Michigan is a Nondis-

cunator, Afirnve Action Employer.

POSTDOCTORAL FELLOWSHIP INMOLECULAR MECHANISMS OF

DNA DAMAGE,REPAIR AND MUTAGENESIS

Postdoctoral positions are available to participate inongoing studies on the molecular mechanisms involvedin the sequence-specific DNA damage produced bytargeted antitumor antibiotic radicals. Current researchinterest centers around agents that, upon activation to aradical species, attack specific sites in DNA deoxyriboseto generate novel doubIe-stranded lesions. Experimenta-tion will involve elucidation of the detailed chemical andbiochemical mechanisms involved in DNA damage for-mation and repair, the DNA structural requirementsleading to sequence-specific lesions, the relation of theselesions to mutagenesis, and the use of such agents as

bsof unusual DNA structures. A background inbiochemistry or chemistry and/or molecular biolo-

gy is desirable. Please send curnculum vitae, publicationsLst and names of at least two references to: Dr. IrvingH. Goldberg, Department of Biological Chemistyand Molecular Pharmacology, Harvard MedicalSchool, 250 Longwood Avenuc, Boston, MA 02115.

POSTDOCTORAL FELLOWSHIPSIN VISION RESEARCHEMORY UNIVERSITYATLANTA, GEORGIA

Postdoctoral fellowships to begin 1 July 1989 are nowbeing offered by the Department of Ophthalmology atEmory Univcrsity in vision research. Individuals withM.D., D.V.M. and/or Ph.D. degrees are sought. Theprogram will allow training in several research areas:immunology, pharmacology, recombinant DNA, physi-ology, biochemistry, and experimental pathology. Spe-cial emphasis will be placed upon research training inclinically relevant problems. Stipends are dependentupon the trainee's previous experience and will range upto $30,000 per year. Applicants must be citizens or non-citizen nationals ofthe United States or must have been lawfullyadmitted for penmanent residency at the time of appointment.Deadline for receipt ofsuch applicantons is 15 November1988. Applicants will be notlfied by 1 January 1989 oftheir acceptance into the program. Interested personspease contact: Dr. Bernard E. McCarey, Dep entof Ophthalmology, Emory University, 132 CliftonRoad, N.E., Atlanta, GA 30322. Equal Opportunity/Afirmiative Action Employer.

SYMPOSIUM

ADVANCES INCHEMOTHERAPY OF AIDS

23 SEPTEMBER 1988

Symposium on recent advances in basic research ondevelopment of novel drugs and pharmacologic ap-proaches against AIDS. Dctails and application formsfrom: Division of Clinical Pharmacology, Universityof Alabama at Birmingha Box 600, BirminAL 35294.

MARKETPLACE

"'powerful and easy to use..."Ask for our Ire 16 page brochure that includes

complete program descriptions and detailed technicalapplication notes.

2034 East Fort Union Blvd acS fSaft Lake City, Utah 84121telephone: (801) 943-0290 SCIENTIFIC SOFTWARE

Circle No. 105 on Readers' Service Card

I

SCIENCE, VOL. 241

FELLOWSHIPSPOSITIONS OPEN

Syva, a subsidiary of Syntex, is a lead-er in medical diagnostics - develop-ing, manufacturing and marketing teststo diagnose infectious diseases and todetect and quantify clinically signifi-cant substances in patients' bodyfluids. We provide opportunities forinnovative research few biotechnologycompanies can match...in some of thefinest facilities in the country.

Currently, we have a number of op-portunities at all levels in the followingdisciplines:*Biochemistry *Organic Chemistry*Surface Chemistry oBlood TYpingoMicrobiology eMolecular Biology

*Nucleic Acid Probes

Creative senior scientists withexperience in the above disciplines areneeded for laboratory positions relatedto new assay development in both ourResearch and Development groups. Toqualify for these key openings, a PhDor equivalent is essential with relatedpost doctoral and/or industrialtraining.

In addition, we are looking forpostdoctoral fellows and BSIMS levelscientists with strong analyficalcapabilities. Some positions requireindustrial experience.

Syva's excellent benefit package in-cludes generous relocation assistance.Please send your resume or CV to:Syva, Dept. DP/S, Professional Staff-ing, P.O. Box 10058, Palo Alto, CA94303. An equal opportunity employer.

A SyntexCompany

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