Percutaneous VSD closure - SECARDIOPED Percutaneous VSD closure Gianfranco Butera San Donato...
Transcript of Percutaneous VSD closure - SECARDIOPED Percutaneous VSD closure Gianfranco Butera San Donato...
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IRCCS Policlinico San Donato
Percutaneous VSD closure
Gianfranco Butera San Donato Milanese - Italy
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IRCCS Policlinico San Donato
Patients selection• Pts having hemodynamically significant VSD • Left ventricular enlargement (left ventricular overload),defined as a LVEDD > +2 SD above the mean for the patient’s age. . Hystory of bacterial endocarditis • Clinical evaluation, EKG, Chest-x-ray, echo !
• Exclusion criteria: !
• Body weight < 5-6 Kg for mVSD and <8-10 kg for pmVSD
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Which patients with congenital VSD are not suitable to percutaneous closure?
Exclusion criteria: Supracrystal VSD ! Malalignement VSD Associated significant aortic regurgitation Prolapse of aortic cusp ! Sub-aortic stenosis ! Sub-pulmonary stenosis (RV mid ventricular stenosis) ! Eisenmenger syndrome ! High pulmonary pressures (PAR > 2/3 SAR)
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VSD
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VSD
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Muscular VSDPre-procedural Echocardiographic evaluation (TTE/TEE)
Size (measure in different views) !!Number (single/multiple) !!Location (apical/mid muscular/high muscular) !!Associated defects (ASD/pulmonary stenosis/aortic coarctation/others) !!Contra-indication to percutaneous closure
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Muscular VSDProcedural Echocardiographic evaluation (TEE)
Integrate data from fluoroscopy and EKG !Analysis of VSD (Size/Number/Location/Associated defects Contra-indication to percutaneous closure) !Check position of : Guide wire (TV, AoV) ! Ventricular function during manoeuvres ! Long-sheath (MV, free LV wall, AoV, TV)
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Muscular VSD
Policlinico San Donato IRCCS
!!
Usually it is quite easy to analyse the margins and measure the size of the defect
!Margins are usually well seen
!Measure of the defect in 2D
and with color (measure at the “PISA”)
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Muscular VSD
Policlinico San Donato IRCCS
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Muscular VSD
Policlinico San Donato IRCCS
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Procedure protocol
• General anesthesia
• Full heparinization
• Arterial and venous access
• Basal hemodynamics
• Assessment of VSD size and location
• Fluoro and TEE monitoring
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Amplatzer muscular VSD occluder
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IRCCS Policlinico San Donato
Amplatzer muscular VSD occluder
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IRCCS Policlinico San Donato
Amplatzer muscular VSD occluder
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IRCCS Policlinico San Donato
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IRCCS Policlinico San Donato
Multiple Muscular VSD’s Implantation of 2 devices
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IRCCS Policlinico San Donato
Retrograde closure of high muscular VSD
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IRCCS Policlinico San Donato
Retrograde closure of high muscular VSD
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IRCCS Policlinico San Donato
Retrograde closure of high muscular VSD
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IRCCS Policlinico San Donato
Retrograde closure of high muscular VSD
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IRCCS Policlinico San Donato
Retrograde closure of high muscular VSD (interrupted IVC and azygos continuation)
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IRCCS Policlinico San Donato
Retrograde closure of high muscular VSD (interrupted IVC and azygos continuation)
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Complications
Device entangled in the tricuspid valve !!!Sometimes worsening of TR during f-up
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Residual post-surgery VSD
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IRCCS Policlinico San Donato
Residual post-surgical VSD !
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IRCCS Policlinico San Donato
Residual post-surgical VSD !
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IRCCS Policlinico San Donato
Residual post-surgical VSD !
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IRCCS Policlinico San Donato
Residual post-surgical VSD !
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IRCCS Policlinico San Donato
Residual post-surgical VSD !
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Istituto Policlinico San Donato
Non standard procedure (aortic approach)
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Istituto Policlinico San Donato
Non standard procedure (aortic approach)
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IRCCS Policlinico San Donato
Residual post-surgical VSD !
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Residual post-surgical VSD !
Balloon sizing of the defect - exact site, size, and position of the residual shunt - not ‘stop-flow’ in most of the cases but a ‘pull-through’ !TEE and angiography It is essential to have expert TEE guidance !Aortic retrograde approach - easier in these cases. -anterograde approach: it can be difficult to advance the sheath tip to the LV apex (surgical patches?) - there is less space in the sub-aortic region to deploy the LV disc and increased risk of complications. - if the LV disc is deployed in the ascending aorta, it is more difficult to retrieve it back in the sheath, if required, with increased risk of damaging the aortic valve. !Limitation subjects who may accommodate the use of a 8Fr long-sheath in the femoral artery.
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IRCCS Policlinico San Donato
Amplatzer membranous VSD occluder “eccentric device”
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IRCCS Policlinico San Donato
Amplatzer membranous VSD occluder “eccentric device”
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IRCCS Policlinico San Donato
Amplatzer membranous VSD occluder “eccentric device”
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Perimembranous VSDPre-procedural Echocardiographic evaluation (TTE)
Size (measure in different views) !Number (single/multiple) !Extension (inlet/trabecular/outlet) !Aneurysm/Pouches from the TV/ septal L of the TV !Associated defects (ASD/pulmonary stenosis/aortic coarctation/others) !Contra-indication to percutaneous closure
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Perimembranous VSDProcedural Echocardiographic evaluation (TEE)
Integrate data from fluoroscopy, EKG !Analysis of VSD (Size/Number/Location/Aneurysm/Associated defects Contra-indication to percutaneous closure) !Check position of : Guide wire (TV, AoV) ! Ventricular function during manouevres ! Long-sheath (MV, free LV wall, AoV,TV)
Policlinico San Donato IRCCS
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Perimembranous VSD Echocardiographic evaluation
Policlinico San Donato IRCCS
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Perimembranous VSD Echocardiographic evaluation
Policlinico San Donato IRCCS
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Perimembranous VSD Echocardiographic evaluation
Policlinico San Donato IRCCS
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Perimembranous VSDProcedural Echocardiographic evaluation (TEE)
Check interatrial septum, direction of shunting on PFO/ASD !Check tricuspid valve !Check device deployement: ! LV disk (MV, free LV wall, IVS, Ao valve) ! Connecting waist ! RV disk (IVS, TV) !
Policlinico San Donato IRCCS
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Perimembranous VSDProcedural Echocardiographic evaluation (TEE)
Check device position: ! malposition? embolization? !Pericardial effusion? !Regurgitation of AoV,MV,TV? !
Policlinico San Donato IRCCS
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IRCCS Policlinico San Donato
Perimembranous VSD Closure with “eccentric device”
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IRCCS Policlinico San Donato
Perimembranous VSD
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IRCCS Policlinico San Donato
Perimembranous VSD
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IRCCS Policlinico San Donato
Perimembranous VSD
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IRCCS Policlinico San Donato
Perimembranous VSD with “septal aneurysm”
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IRCCS Policlinico San Donato
Multiple Perimembranous VSD with “septal aneurysm”
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IRCCS Policlinico San Donato
Multiple Perimembranous VSD with septal aneurysm
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IRCCS Policlinico San Donato
Multiple Perimembranous VSD with septal aneurysm
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IRCCS Policlinico San Donato
Perimembranous VSD with “septal aneurysm” Closure with Muscular VSD occluder
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IRCCS Policlinico San Donato
Perim.VSD + ASD + PDA
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IRCCS Policlinico San Donato
Amplatzer perimembranous VSD occluder
Tips, Tricks, Hints and Pitfalls !
➢ Difficulties in advancing the sheath over the AV circuit: start all over again !➢ Desaturation when the sheath is in place: R-to-L shunt through the PFO/ASD due to “functional” tricuspid stenosis !
➢ Retrograde closure from the the aortic side !
➢ Difficulties in placing the sheath towards the LV apex: open the device from the aorta
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Istituto Policlinico San Donato
Complete -AVBLarge variability in
!Clinical presentation (asymptomatic-mild symptoms-syncope-sudden death) !Timing (up to 2 years after procedure) !Answer to steroids
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IRCCS Policlinico San Donato
Perimembranous VSD and cAV block:possible mechanisms and risk factors
Early Heart block
Trauma/edema from catheter manipulation and/or device
Inflammatory reaction to device
Late Heart blockTrauma from continuing expansion of an oversized device
fibrosis
Down’s Syndrome
Down’s Syndrome
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IRCCS Policlinico San Donato
Perimembranous VSD
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“Oversizing”
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“Oversizing”
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IRCCS Policlinico San Donato
Perimembranous VSD
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IRCCS Policlinico San Donato
Perimembranous VSD
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IRCCS Policlinico San Donato
Perimembranous VSD
Transcatheter closure of congenital ventricular septal defects in adults: Mid-term results and complications.
Int J Cardiol 2008 Jan 28
M . Chessa, G. Butera, M. Carminati.
0% occurrence of cAVB
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IRCCS Policlinico San Donato
Perimembranous VSD
0% occurrence of cAVB in children > 5 years old
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IRCCS Policlinico San Donato
Perimembranous VSD
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Closure of PMVSDs Tomorrow
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AMPLATZER® Membranous VSD Occluder 2
!■ Minimizes Pressure on the Septal Tissue !
!■ The dual-layer waist is engineered to
impart minimal radial pressure against the defect while providing stability !
■ 3mm waist length reduces clamp force on the ventricular septum
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HSD - PEDIATRIC CARDIOLOGY
Thank you for your attention