PATHOLOGYPATHOLOGY

RONI YULIWAR

PATHOLOGYPATHOLOGY

A bridging discipline involving both basic science and clinical

practice and is devoted to the study of the

structural and functional changes in cells, tissues, and organs that underlie

“diseases.”

Pathology could be defined as the specialty that employs morphological techniques to explain symptoms and signs, to determine the cause of

death, to guide therapy, and to predict the

evolution of disease.

PATHOLOGY

Director, Rockefeller Institute of Experimental Pathology.

"Pathology is far more important for us than physiology or pharmacology, and the background of medicine than general science. Pathology is the fundamental branch of medicine"

Simon Flexner

"You can take notes for 25 years, from morning to

evening, by the patient's bedside on diseases of the lung, heart and stomach, and the result will be a long list of confusing symptoms leading to

incoherent conclusions. Open a few bodies, and you

will see darkness immediately recede".

Xavier Bichat

Rudolf Virchow Rudolf Virchow (1821-1902)(1821-1902)

Father of Modern Pathology

His major contribution was the idea that pathologic reactions were reactions of cells.

Why Study Why Study PathologyPathology

1. Because it’s the most important So that all the Basic Science trivia has a practical or clinical application

2. Minimize ignorance

Why Study Why Study PathologyPathology

3. To understand the mechanisms of symptom production

4. Provides a reason or rational for treatment choices

Why Study Why Study PathologyPathology

5. To intelligently communicate with professional colleagues

6. So that you can correctly explain things to your patients

7. Understand what you read

PATHOLOGYPATHOLOGY

Clinical pathology

Forensic pathology

Experimental Pathology

Anatomic pathology

PATHOLOGYPATHOLOGY

The four aspects of a disease process that form

the core of pathology

1. Etiology

2. Pathogenesis

3. Morphologic change

4. Clinical significance

EtiologyEtiology

The cause

PathogenesisPathogenesis

The mechanism

Morphologic Morphologic changechange

Alteration of structure

Clinical Clinical significancesignificance

Signs & Symptoms

What is the What is the responsibility of responsibility of the Chiropractic the Chiropractic

physician physician for Pathologyfor Pathology

FIND IT FIND IT

AND IF POSSIBLE AND IF POSSIBLE

FIX ITFIX IT

How is pathology How is pathology detecteddetected

Or how do you find itOr how do you find itSigns & SymptomsImaging

Laboratory TestingBiopsy

Autopsy

SEARCH BY USING

YOUR CLINICAL SKILLS

Chapter 1 Cell Injury, Death and AdaptationChapter 2, Acute and Chronic Inflammation Chapter 3, Repair: Cell Regeneration, Fibrosis and Wound Healing Chapter 4, Hemodynamic Disorders,Thrombosis and Schock, Chapter 5, Disorders of the Immune System Chapter 6 NeoplasiaChapter Disease of Erythrocytes and Luekocytes

LECTURE/LABORATORY SERIES OUTLINE: