GBIME0071MR Diabetes Care Devices Market to … Care Devices Market to 2018 ... 6.2.21 Diabetes Care...

Diabetes Care Devices Market to 2018 Integrated Insulin Pumps with Continuous Glucose Monitoring Technology to Add a New Dimension to Diabetes Management

GBI Research Report Guidance

GBIME0071MR / Published AUG 2012

© GBI Research. This is a licensed product and is not to be photocopied

GBI Research Report Guidance

The report includes an executive summary capturing the key points that determine the dynamics of the diabetes care devices market. Competition in the industry and key categories, segments and geographical regions are also outlined.

The ‘Market Characterization’ chapter provides information on the market size for the historic period (2004-2011) and the forecast period (2011-2018). It also has information related to the diabetes care devices market trends, market dynamics, and the competitive landscape. In the market dynamics section, comprehensive information is provided on market drivers and restraints.

The ‘Category Analysis and Forecasts’ chapter discusses glucose monitoring devices and insulin delivery devices categories. Market size information for the historic period (2004-2011) and the forecast period (2011-2018) is discussed for each category, along with market dynamics.

This is followed by the ‘Country Analysis and Forecasts’ section. Market size information for the historic period (2004-2011) and the forecast period (2011-2018) is provided for the US, Canada, the UK, France, Germany, Italy, Spain, Japan, China, India, Australia and Brazil. A cross-country analysis of these countries is also discussed.

The ‘Competitive Assessment’ chapter gives profiles of the leading diabetes care device companies and the companies’ key products.

The ‘Pipeline Product Analysis’ chapter focuses on the pipeline products in various categories. Key pipeline products are listed and discussed in detail, and product approval and expected launch dates are also provided for a number of products.

The ‘Consolidation Landscape’ chapter discusses the consolidation landscape in the diabetes care devices industry. This chapter examines the total number of deals that took place during 2007-2012 (Q1, Q2).


© GBI Research. This is a licensed product and is not to be photocopied

Executive Summary

Executive Summary

The Global Diabetes Care Devices Market is Forecast to Witness Moderate Growth During 2011−2018

The global market for diabetes care devices is forecast to reach $XX billion by 2018, with a Compound Annual Growth Rate (CAGR) of XX% from 2011 to 2018. Glucose monitoring devices will be the largest category in the market, with a value of $XX billion by 2018. The insulin delivery devices market was valued at $XX billion in 2011, and is forecast to grow at a CAGR of XX% to reach revenues of $XX billion in 2018.

Diabetes Care Devices Market, Global, Overall Revenues ($bn), 2011−2018

2011 2018

Rev

enue

($bn

)

CAGR (2011-2018):XX%

Source: GBI Research’s proprietary database [accessed on May 2, 2012]; primary research interviews with marketing managers and other industry experts.

The market is primarily expected to be driven during the forecast period by the large patient pool suffering from diabetes and the rapid uptake of innovative, minimally or non-invasive products. Examples include the C8 MediSensors Optical Glucose Monitor, NBM-200G, Easy Check Breath Glucose and EyeSense Blood Glucose Measurement Device, which utilize a patient’s sweat, exhaled breath or a fluorescent eye signal to measure blood glucose levels. Integrated Continuous Glucose Monitoring (CGM) systems will also contribute to the growth of the glucose monitoring devices market.

Compelling clinical needs, expanding research activities and applications to develop non-invasive therapies will accelerate technological innovations in diabetes care devices. Moreover, increasing awareness, improving diagnosis and treatment rates and a growing demand for safer, more effective, more accurate and cost-effective therapies for diabetes will lead to increased adoption rates for diabetes care devices.

The global market for diabetes care devices is forecast to reach $XX billion by 2018, with a CAGR of XX% from 2011 to 2018


Page 6 © GBI Research. This is a licensed product and is not to be photocopied

Table of Contents

1 Table of Contents

1 Table of Contents................................................................................................................................. 6 1.1 List of Tables............................................................................................................................. 9 1.2 List of Figures...........................................................................................................................11

2 Introduction........................................................................................................................................12 3 Global Diabetes Care Devices Market - Overview.................................................................................13

3.1 Disease Overview.....................................................................................................................13 3.1.1 Types of Diabetes.............................................................................................................13 3.1.2 Prevalence .......................................................................................................................13 3.1.3 Diabetes Care Devices ......................................................................................................13

4 Global Diabetes Care Devices Market - Market Characterization ..........................................................14 4.1 Diabetes Care Devices Market, Global, Revenue ($bn), 2004-2011............................................14 4.2 Diabetes Care Devices Market, Global, Revenue ($bn), 2011-2018............................................15 4.3 Diabetes Care Devices Market, Global, Key Company Share (%), 2011.......................................16 4.4 Global Diabetes Care Devices Market: Key Trends ....................................................................17

4.4.1 Increase in Healthcare Spending Attributable to Diabetes .................................................17 4.4.2 Increase in Awareness to Help Control Diabetes and Manage Complications......................18

4.5 Global Diabetes Care Devices Market: Market Dynamics...........................................................19 4.5.1 Market Drivers.................................................................................................................19 4.5.2 Market Restraints ............................................................................................................22

5 Global Diabetes Care Devices Market - Category Analysis.....................................................................24 5.1 Glucose Monitoring Devices Market, Global, Revenue ($m), 2004-2011 ....................................24 5.2 Glucose Monitoring Devices Market, Global, Revenue ($m), 2011-2018 ....................................25 5.3 Glucose Monitoring Devices Market, Global, Key Company Share (%), 2011..............................27 5.4 Glucose Monitoring Devices Market: Market Dynamics ............................................................28

5.4.1 Market Drivers.................................................................................................................28 5.4.2 Market Restraints ............................................................................................................31

5.5 Insulin Delivery Devices Market, Global, Revenue ($m), 2004-2011...........................................32 5.6 Insulin Delivery Devices Market, Global, Revenue ($m), 2011-2018...........................................33 5.7 Insulin Delivery Devices Market, Global, Key Company Share (%), 2011.....................................34 5.8 Insulin Devices Market: Market Dynamics ................................................................................35

5.8.1 Market Drivers.................................................................................................................35 5.8.2 Market Restraints ............................................................................................................36

6 Global Diabetes Care Devices Market - Country Analysis ......................................................................38 6.1 Global Diabetes Care Devices Market: Cross Country Analysis...................................................38 6.2 Historic and Forecast Revenue, By Country...............................................................................39

6.2.1 Diabetes Care Devices Market, the US, Revenue ($m), 2004-2011......................................39 6.2.2 Diabetes Care Devices Market, the US, Revenue ($m), 2011-2018......................................40 6.2.3 Diabetes Care Devices Market, Canada, Revenue ($m), 2004-2011....................................41 6.2.4 Diabetes Care Devices Market, Canada, Revenue ($m), 2011-2018....................................42 6.2.5 Diabetes Care Devices Market, Germany, Revenue ($m), 2004-2011..................................43 6.2.6 Diabetes Care Devices Market, Germany, Revenue ($m), 2011-2018..................................44 6.2.7 Diabetes Care Devices Market, France, Revenue ($m), 2004-2011 .....................................45 6.2.8 Diabetes Care Devices Market, France, Revenue ($m), 2011-2018 .....................................46 6.2.9 Diabetes Care Devices Market, the UK, Revenue ($m), 2004-2011 .....................................47 6.2.10 Diabetes Care Devices Market, the UK, Revenue ($m), 2011-2018 .....................................48 6.2.11 Diabetes Care Devices Market, Italy, Revenue ($m), 2004-2011.........................................49 6.2.12 Diabetes Care Devices Market, Italy, Revenue ($m), 2011-2018.........................................50 6.2.13 Diabetes Care Devices Market, Spain, Revenue ($m), 2004-2011 .......................................51 6.2.14 Diabetes Care Devices Market, Spain, Revenue ($m), 2011-2018 .......................................52 6.2.15 Diabetes Care Devices Market, Australia, Revenue ($m), 2004-2011..................................53



Table of Contents

6.2.16 Diabetes Care Devices Market, Australia, Revenue ($m), 2011-2018..................................54 6.2.17 Diabetes Care Devices Market, Japan, Revenue ($m), 2004-2011.......................................55 6.2.18 Diabetes Care Devices Market, Japan, Revenue ($m), 2011-2018.......................................56 6.2.19 Diabetes Care Devices Market, China, Revenue ($m), 2004-2011.......................................57 6.2.20 Diabetes Care Devices Market, China, Revenue ($m), 2011-2018.......................................58 6.2.21 Diabetes Care Devices Market, India, Revenue ($m), 2004-2011........................................59 6.2.22 Diabetes Care Devices Market, India, Revenue ($m), 2011-2018........................................60 6.2.23 Diabetes Care Devices Market, Brazil, Revenue ($m), 2004-2011 .......................................61 6.2.24 Diabetes Care Devices Market, Brazil, Revenue ($m), 2011-2018 .......................................62

7 Global Diabetes Care Devices Market - Competitive Assessment..........................................................63 7.1 F. Hoffmann-La Roche Ltd. .......................................................................................................63

7.1.1 Business Overview............................................................................................................64 7.1.2 Key Marketed Products ....................................................................................................64

7.2 LifeScan, Inc.............................................................................................................................64 7.2.1 Business Overview............................................................................................................64 7.2.2 Key Marketed Products ....................................................................................................65

7.3 Medtronic, Inc. ........................................................................................................................65 7.3.1 Business Overview............................................................................................................65 7.3.2 Key Marketed Products ....................................................................................................65

7.4 Novo Nordisk A/S.....................................................................................................................66 7.4.1 Business Overview............................................................................................................66 7.4.2 Key Marketed Products ....................................................................................................66

7.5 Sanofi ......................................................................................................................................67 7.5.1 Business Overview............................................................................................................67 7.5.2 Key Marketed Products ....................................................................................................68

7.6 Eli Lilly and Company ...............................................................................................................68 7.6.1 Business Overview............................................................................................................68 7.6.2 Key Marketed Products ....................................................................................................68

7.7 Bayer HealthCare AG ...............................................................................................................69 7.7.1 Business Overview............................................................................................................69 7.7.2 Key Marketed Products ....................................................................................................69

7.8 Abbott Laboratories.................................................................................................................69 7.8.1 Business Overview............................................................................................................69 7.8.2 Key Marketed Products ....................................................................................................70

7.9 Becton, Dickinson and Company ..............................................................................................70 7.9.1 Business Overview............................................................................................................70 7.9.2 Key Marketed Products ....................................................................................................70

8 Global Diabetes Care Devices Market - Pipeline Analysis ......................................................................71 8.1 Glucose Monitoring Devices: Product Pipeline..........................................................................72

8.1.1 Glucose Monitoring Devices: List of Pipeline Products........................................................72 8.1.2 Glucose Monitoring Devices: Profiles of Key Pipeline Products ...........................................76

8.2 Insulin Delivery Devices: Product Pipeline.................................................................................82 8.2.1 Insulin Delivery Devices: List of Pipeline Products...............................................................82 8.2.2 Insulin Delivery Devices: Profiles of Key Pipeline Products ..................................................84

8.3 Artificial Pancreas: Product Pipeline .........................................................................................90 8.3.1 Artificial Pancreas: List of Pipeline Products ......................................................................90 8.3.2 Artificial Pancreas: Profiles of Key Pipeline Products ..........................................................90

8.4 Other Diabetes Care Devices ....................................................................................................92 8.4.1 Other Diabetes Care Devices: List of Pipeline Products.......................................................92

9 Global Diabetes Care Devices Market - Consolidation Landscape..........................................................93 9.1 Key Deals: 2010-2012 (Q1, Q2).................................................................................................93

9.1.1 EKF Diagnostics Holdings Sells International Brand Licensing AG........................................93



Table of Contents

9.1.2 ActiveCare’s Acquisition of 4G Biometrics..........................................................................94 9.1.3 D. Medical Industries Completes Sale of its 57.5% Stake in NextGen Biomed ......................94 9.1.4 Insulet’s Acquisition of Neighborhood Diabetes.................................................................94 9.1.5 Roche Holding’s Acquisition of Medingo from Elron Electronic Industries ...........................94

9.2 Key Partnership Deals: 2007-2012 (Q1, Q2) ..............................................................................95 9.2.1 Insulet’s Agreement with Ypsomed Holding ......................................................................96 9.2.2 Haselmeier’s Distribution Agreement with Biocon .............................................................96 9.2.3 Roche Diagnostics’ Distribution Agreement with DexCom..................................................96 9.2.4 Cellnovo’s Technology Integration Agreement with LifeScan..............................................96 9.2.5 Bayer HealthCare Diabetes Care’s Partnership with Medtronic ..........................................96 9.2.6 PositiveID’s Agreement with HMD BioMedical ..................................................................97 9.2.7 Powder Pharma’s Agreement with Health-Chem Diagnostics.............................................97 9.2.8 Insulet’s Distribution Agreement with GlaxoSmithKline .....................................................97 9.2.9 Dance Pharma’s Licensing Agreement with Aerogen .........................................................97 9.2.10 EyeSense’s Agreement with Qiagen ..................................................................................97 9.2.11 AgaMatrix’s Agreement with Sanofi-Aventis .....................................................................97 9.2.12 JDRF’s Agreement with Becton, Dickinson and Company ...................................................98 9.2.13 Insulet’s Distribution Agreement with Ypsomed Holding....................................................98 9.2.14 Luminous Medical’s Agreement with a Supplier of Electrochemical Sensors .......................98 9.2.15 Arkray’s Distribution Agreement with Nipro Corporation...................................................98 9.2.16 Edwards Lifesciences’ Agreement with DexCom ................................................................98 9.2.17 Oxygen Biotherapeutics’ Agreement with Glucometrics.....................................................99 9.2.18 Smiths Medical’s Agreement with Abbott Labs..................................................................99 9.2.19 Mankind Pharma’s Agreement with Roche Diagnostics .....................................................99 9.2.20 DexCom’s Joint Venture with Animas................................................................................99 9.2.21 Insulet Corporation’s Partnership with DexCom.................................................................99 9.2.22 BioPharmetics’ Agreement with HMD Biomedical ...........................................................100

10 Appendix ..........................................................................................................................................101 10.1 Definitions.............................................................................................................................101

10.1.1 Diabetes Care Devices ....................................................................................................101 10.1.2 Glucose Monitoring Devices............................................................................................101 10.1.3 Insulin Delivery Devices ..................................................................................................101

10.2 Acronyms ..............................................................................................................................102 10.3 Sources..................................................................................................................................104 10.4 Research Methodology ..........................................................................................................105

10.4.1 Secondary Research .......................................................................................................105 10.4.2 Primary Research ...........................................................................................................105 10.4.3 Models ..........................................................................................................................106 10.4.4 Forecasts .......................................................................................................................106 10.4.5 Expert Panels .................................................................................................................106

10.5 Contact Us.............................................................................................................................106 10.6 Disclaimer..............................................................................................................................107



Table of Contents

1.1 List of Tables

Table 1: Diabetes Care Devices Market, Global, Revenue ($bn), 2004-2011 ...........................................14 Table 2: Diabetes Care Devices Market, Global, Revenue ($bn), 2011-2018 ...........................................15 Table 3: Diabetes Care Devices Market, Global, Key Company Revenue ($m), 2011 ...............................16 Table 4: Glucose Monitoring Devices Market, Global, Revenue ($m), 2004-2011 ...................................24 Table 5: Glucose Monitoring Devices Market, Global, Revenue ($m), 2011-2018 ...................................25 Table 6: Glucose Monitoring Devices Market, Global, Key Company Revenue ($m), 2011 ......................27 Table 7: Glucose Monitoring Devices Market, Global, Key Product Launches, 2011−2012 ......................28 Table 8: Insulin Delivery Devices Market, Global, Revenue ($m), 2004-2011..........................................32 Table 9: Insulin Delivery Devices Market, Global, Revenue ($m), 2011-2018..........................................33 Table 10: Insulin Delivery Devices Market, Global, Key Company Revenue ($m), 2011.............................34 Table 11: Diabetes Care Devices Market, Cross Country Analysis, Global, CAGR, 2004-2018.....................38 Table 12: Diabetes Care Devices Market, the US, Revenue ($m), 2004-2011............................................39 Table 13: Diabetes Care Devices Market, the US, Revenue ($m), 2011-2018............................................40 Table 14: Diabetes Care Devices Market, Canada, Revenue ($m), 2004-2011...........................................41 Table 15: Diabetes Care Devices Market, Canada, Revenue ($m), 2011-2018...........................................42 Table 16: Diabetes Care Devices Market, Germany, Revenue ($m), 2004-2011........................................43 Table 17: Diabetes Care Devices Market, Germany, Revenue ($m), 2011-2018........................................44 Table 18: Diabetes Care Devices Market, France, Revenue ($m), 2004-2011............................................45 Table 19: Diabetes Care Devices Market, France, Revenue ($m), 2011-2018............................................46 Table 20: Diabetes Care Devices Market, the UK, Revenue ($m), 2004-2011............................................47 Table 21: Diabetes Care Devices Market, the UK, Revenue ($m), 2011-2018............................................48 Table 22: Diabetes Care Devices Market, Italy, Revenue ($m), 2004-2011 ...............................................49 Table 23: Diabetes Care Devices Market, Italy, Revenue ($m), 2011-2018 ...............................................50 Table 24: Diabetes Care Devices Market, Spain, Revenue ($m), 2004-2011..............................................51 Table 25: Diabetes Care Devices Market, Spain, Revenue ($m), 2011-2018..............................................52 Table 26: Diabetes Care Devices Market, Australia, Revenue ($m), 2004-2011 ........................................53 Table 27: Diabetes Care Devices Market, Australia, Revenue ($m), 2011-2018 ........................................54 Table 28: Diabetes Care Devices Market, Japan, Revenue ($m), 2004-2011 .............................................55 Table 29: Diabetes Care Devices Market, Japan, Revenue ($m), 2011-2018 .............................................56 Table 30: Diabetes Care Devices Market, China, Revenue ($m), 2004-2011 .............................................57 Table 31: Diabetes Care Devices Market, China, Revenue ($m), 2011-2018 .............................................58 Table 32: Diabetes Care Devices Market, India, Revenue ($m), 2004-2011 ..............................................59 Table 33: Diabetes Care Devices Market, India, Revenue ($m), 2011-2018 ..............................................60 Table 34: Diabetes Care Devices Market, Brazil, Revenue ($m), 2004-2011..............................................61 Table 35: Diabetes Care Devices Market, Brazil, Revenue ($m), 2011-2018..............................................62 Table 36: Diabetes Care Devices Market, Global, Pipeline Analysis, by Category, 2012.............................71 Table 37: Diabetes Care Devices Market, Glucose Monitoring Devices, Global, List of Pipeline Products,

Table 1, 2012..........................................................................................................................72 Table 38: Diabetes Care Devices Market, Glucose Monitoring Devices, Global, List of Pipeline Products,



Table 4, 2012..........................................................................................................................75 Table 41: Diabetes Care Devices Market, Pipeline Analysis - Enlite Sensor, 2012......................................76 Table 42: Diabetes Care Devices Market, Pipeline Analysis - C8 MediSensors Optical Glucose Monitor,

2012.......................................................................................................................................77 Table 43: Diabetes Care Devices Market, Pipeline Analysis - GlucoTrack, 2012.........................................77 Table 44: Diabetes Care Devices Market, Pipeline Analysis - Integrated Guardian Real-Time Continuous

Glucose Monitoring System, 2012 ...........................................................................................78 Table 45: Diabetes Care Devices Market, Pipeline Analysis - NBM- 200G, 2012........................................78 Table 46: Diabetes Care Devices Market, Pipeline Analysis - OptiScannner, 2012.....................................79 Table 47: Diabetes Care Devices Market, Pipeline Analysis - Animas Vibe Insulin Pump and CGM System,

2012.......................................................................................................................................79 Table 48: Diabetes Care Devices Market, Pipeline Analysis - Easy Check Breath Glucose Detection System,

2012.......................................................................................................................................80



Table of Contents

Table 49: Diabetes Care Devices Market, Pipeline Analysis - EyeSense Blood Glucose Measurement Device, 2012.......................................................................................................................................80

Table 50: Diabetes Care Devices Market, Pipeline Analysis - Redscan, 2012.............................................81 Table 51: Diabetes Care Devices Market, Pipeline Analysis - 5th Generation Short-term Sensor, 2012......81 Table 52: Diabetes Care Devices Market, Insulin Delivery Devices, Global, List of Pipeline Products, Table 1,

2012.......................................................................................................................................82 Table 53: Diabetes Care Devices Market, Insulin Delivery Devices, Global, List of Pipeline Products, Table 2,

2012.......................................................................................................................................83 Table 54: Diabetes Care Devices Market, Pipeline Analysis - Paradigm Veo System, 2012 ........................84 Table 55: Diabetes Care Devices Market, Pipeline Analysis - ClikSTAR, 2012 ............................................84 Table 56: Diabetes Care Devices Market, Pipeline Analysis - NovoPen Echo, 2012 ...................................85 Table 57: Diabetes Care Devices Market, Pipeline Analysis - Next Generation OneTouch Ping, 2012 ........85 Table 58: Diabetes Care Devices Market, Pipeline Analysis - Eros Insulin Pump, 2012 ..............................86 Table 59: Diabetes Care Devices Market, Pipeline Analysis - Needle-Free Injection Device, 2012..............86 Table 60: Diabetes Care Devices Market, Pipeline Analysis - Spring Zone Insulin Delivery System, 2012 ...87 Table 61: Diabetes Care Devices Market, Pipeline Analysis - Solo MicroPump Insulin Delivery System, 2012

...............................................................................................................................................87 Table 62: Diabetes Care Devices Market, Pipeline Analysis - PaQ Insulin Delivery Device, 2012................88 Table 63: Diabetes Care Devices Market, Pipeline Analysis - Jewel Pump, 2012 .......................................89 Table 64: Diabetes Care Devices Market, Pipeline Analysis - Cellnovo Wireless Insulin Pump System, 2012

...............................................................................................................................................89 Table 65: Diabetes Care Devices Market, Artificial Pancreas, Global, List of Pipeline Products, 2012.........90 Table 66: Diabetes Care Devices Market, Pipeline Analysis - Artificial Pancreas, 2012 ..............................90 Table 67: Diabetes Care Devices Market, Pipeline Analysis - Bionic Pancreas, 2012..................................91 Table 68: Diabetes Care Devices Market, Pipeline Analysis - Closed-Loop Artificial Pancreas System, 2012

...............................................................................................................................................91 Table 69: Diabetes Care Devices Market, Pipeline Analysis - MiniMed Closed Loop Insulin Delivery System,

2012.......................................................................................................................................91 Table 70: Diabetes Care Devices Market, Other Diabetes Care Devices, Global, List of Pipeline Products,

2012.......................................................................................................................................92 Table 71: Diabetes Care Devices Market, Global, Key Deals, 2010-2012 (Q1, Q2).....................................93 Table 72: Diabetes Devices Market, Global, Key Partnerships, 2007-2012 (Q1, Q2)..................................95



Table of Contents

1.2 List of Figures

Figure 1: Diabetes Care Devices Market, Global, Revenue ($bn), 2004-2011 ...........................................14 Figure 2: Diabetes Care Devices Market, Global, Revenue ($bn), 2011-2018 ...........................................15 Figure 3: Diabetes Care Devices Market, Global, Key Company Share (%), 2011 .....................................16 Figure 4: Diabetes Care Devices Market, Global, Healthcare Expenditure ($bn), by Country, 2010−2030 .17 Figure 5: Diabetes Care Devices Market, Global, Number of People with Diabetes (20-79 years), by

Country, 2011−2030................................................................................................................20 Figure 6: Glucose Monitoring Devices Market, Global, Revenue ($m), 2004-2011 ...................................24 Figure 7: Glucose Monitoring Devices Market, Global, Revenue ($m), 2011-2018 ...................................25 Figure 8: Glucose Monitoring Devices Market, Global, Key Company Share (%), 2011 .............................27 Figure 9: Insulin Delivery Devices Market, Global, Revenue ($m), 2004-2011..........................................32 Figure 10: Insulin Delivery Devices Market, Global, Revenue ($m), 2011-2018..........................................33 Figure 11: Insulin Delivery Devices Market, Global, Key Company Share (%), 2011....................................34 Figure 12: Diabetes Care Devices Market, Cross Country Analysis, Global, CAGR, 2004-2018.....................38 Figure 13: Diabetes Care Devices Market, the US, Revenue ($m), 2004-2011............................................39 Figure 14: Diabetes Care Devices Market, the US, Revenue ($m), 2011-2018............................................40 Figure 15: Diabetes Care Devices Market, Canada, Revenue ($m), 2004-2011...........................................41 Figure 16: Diabetes Care Devices Market, Canada, Revenue ($m), 2011-2018...........................................42 Figure 17: Diabetes Care Devices Market, Germany, Revenue ($m), 2004-2011........................................43 Figure 18: Diabetes Care Devices Market, Germany, Revenue ($m), 2011-2018........................................44 Figure 19: Diabetes Care Devices Market, France, Revenue ($m), 2004-2011............................................45 Figure 20: Diabetes Care Devices Market, France, Revenue ($m), 2011-2018............................................46 Figure 21: Diabetes Care Devices Market, the UK, Revenue ($m), 2004-2011............................................47 Figure 22: Diabetes Care Devices Market, the UK, Revenue ($m), 2011-2018............................................48 Figure 23: Diabetes Care Devices Market, Italy, Revenue ($m), 2004-2011 ...............................................49 Figure 24: Diabetes Care Devices Market, Italy, Revenue ($m), 2011-2018 ...............................................50 Figure 25: Diabetes Care Devices Market, Spain, Revenue ($m), 2004-2011..............................................51 Figure 26: Diabetes Care Devices Market, Spain, Revenue ($m), 2011-2018..............................................52 Figure 27: Diabetes Care Devices Market, Australia, Revenue ($m), 2004-2011 ........................................53 Figure 28: Diabetes Care Devices Market, Australia, Revenue ($m), 2011-2018 ........................................54 Figure 29: Diabetes Care Devices Market, Japan, Revenue ($m), 2004-2011 .............................................55 Figure 30: Diabetes Care Devices Market, Japan, Revenue ($m), 2011-2018 .............................................56 Figure 31: Diabetes Care Devices Market, China, Revenue ($m), 2004-2011 .............................................57 Figure 32: Diabetes Care Devices Market, China, Revenue ($m), 2011-2018 .............................................58 Figure 33: Diabetes Care Devices Market, India, Revenue ($m), 2004-2011 ..............................................59 Figure 34: Diabetes Care Devices Market, India, Revenue ($m), 2011-2018 ..............................................60 Figure 35: Diabetes Care Devices Market, Brazil, Revenue ($m), 2004-2011..............................................61 Figure 36: Diabetes Care Devices Market, Brazil, Revenue ($m), 2011-2018..............................................62 Figure 37: Diabetes Care Devices Market, Global, Competitive Assessment, 2012.....................................63 Figure 38: Diabetes Care Devices Market, Global, Pipeline Analysis, by Category (%), 2012.......................71



Introduction

2 Introduction

The diabetes care devices market is growing at a moderate rate due to an increase in the prevalence of diabetes, changes in lifestyle related factors that are known to cause diabetes such as obesity and physical inactivity, a longer lifespan among people with diabetes, increasing awareness, improving diagnosis and treatment rates, technological advancements, government initiatives, and an increase in clinical trials for the development of innovative and patient-convenient diabetes care products. The diabetes care devices market comprises glucose monitoring devices and insulin delivery devices. The market is constantly driven by R&D activities, which has helped companies to launch technologically advanced products. The market is dominated by Roche, LifeScan, Medtronic, Novo Nordisk, Sanofi, Lilly and Bayer.

Although the glucose monitoring devices category is the largest in terms of revenue, the insulin delivery devices category is expected to witness a stronger growth rate. The glucose monitoring devices market was in dire need of products that measure blood glucose levels by minimally invasive or non-invasive procedures, which forgo the need for painful finger pricks to collect a blood sample for glucose measurement. The glucose monitoring devices pipeline now comprises such products, which comprise innovative technologies capable of measuring blood glucose levels using a patient’s sweat, exhaled breath or a fluorescent eye signal. Continuous glucose monitoring systems dominate the glucose monitoring devices category pipeline. These systems are designed to measure blood glucose levels continuously in the body of a diabetic patient, which enables the identification of glucose trends and the detection of hypo and hyperglycemia events. As technology advances and patient self-management becomes more feasible, the quality of life of diabetes patients will improve.



Global Diabetes Care Devices Market: Market Characterization

4 Global Diabetes Care Devices Market - Market Characterization

4.1 Diabetes Care Devices Market, Global, Revenue ($bn), 2004-2011

The global market for diabetes care devices was worth $XX billion in 2004, and has grown at a CAGR of XX% to reach $XX billion in 2011.

Figure 1: Diabetes Care Devices Market, Global, Revenue ($bn), 2004-2011

2004 2005 2006 2007 2008 2009 2010 2011

Rev

enue

($bn

)

Glucose Monitoring Insulin Delivery


Table 1: Diabetes Care Devices Market, Global, Revenue ($bn), 2004-2011

2004 2005 2006 2007 2008 2009 2010 2011 CAGR

Glucose Monitoring

Insulin Delivery

Total


Glucose monitoring was the largest category, with revenues worth $XX billion in 2011. The insulin delivery devices market was valued at $XX billion in 2011. The market was driven by increased demand for home care diagnostics and increasing affordability, coupled with an increasing diabetic population and efforts to raise awareness of better diabetes management.



Global Diabetes Care Devices Market: Category Analysis

5.3 Glucose Monitoring Devices Market, Global, Key Company Share (%), 2011

The current glucose monitoring devices market is consolidated, as a few players hold a large share of the market. The top XX players in the glucose monitoring devices market in 2011 were identified as LifeScan, Roche, Bayer HealthCare, Abbott, Terumo Corporation and ARKRAY. However, as Bayer seeks to divest its blood glucose meters business unit, the market shares are expected to significantly change in the future.

Figure 8: Glucose Monitoring Devices Market, Global, Key Company Share (%), 2011

LifeScan, Inc.

F. Hoffmann-La Roche Ltd.

Bayer HealthCare AG

Abbott Laboratories

Terumo Corporation

ARKRAY, Inc.

Others

Source: GBI Research’s proprietary database [accessed on August 7, 2012]; primary research interviews with marketing managers and other industry experts.

Table 6: Glucose Monitoring Devices Market, Global, Key Company Revenue ($m), 2011

Company Name Revenue ($m)

LifeScan, Inc.

F. Hoffmann-La Roche Ltd.

Bayer HealthCare AG

Abbott Laboratories

Terumo Corporation

ARKRAY, Inc.

Others

Source: GBI Research’s proprietary database [accessed on August 7, 2012]; primary research interviews with marketing managers and other industry experts.

LifeScan, with its OneTouch brand of glucose monitoring devices, is the dominant player, with revenues of $XXm and a market share of XX% in 2011. LifeScan was closely followed by Roche, which holds a XX% market share and revenues of $XXm in 2011. The postponed launch of the latest Accu-Chek product portfolio in the US affected Roche’s revenues and market share (Roche, annual report, 2011). These companies have successfully launched products and acquired market share in emerging countries, where a higher prevalence of diabetes has led to greater adoption of these devices.

Bayer HealthCare occupied the third position with a market share of XX% of the total glucose monitoring devices market. Abbott, with its FreeStyle line of blood glucose monitoring systems, occupied a smaller market share of XX% of the glucose monitoring devices market in 2011.



Appendix

10 Appendix

10.1 Definitions

10.1.1 Diabetes Care Devices

Diabetes care devices are used in the treatment and management of diabetes. They include home and personal care use devices. The categories included in this market are glucose monitoring devices and insulin delivery devices.

10.1.2 Glucose Monitoring Devices

Glucose monitoring devices are used for time defined or continuous measurement of blood glucose. Glucose monitoring does not include devices for ketone body testing or for any blood constituents other than glucose. This category includes blood glucose meters and blood glucose test strips.

10.1.2.1 Blood Glucose Meters

A blood glucose meter is an electronic diabetic management device used for measuring blood glucose levels.

Continuous Glucose Monitoring Systems

Continuous Glucose Monitoring (CGM) systems are used for the continuous measurement and transmission of blood glucose. They include an implantable sensor with wireless transmission capability and a monitor. Wireless sensors/transmitters are not covered in this segment. One unit of the system includes one monitor.

Traditional Glucose Meters

A traditional blood glucose meter is an external device used for colorimetric or electrochemical glucose measurement of whole blood. Devices for both home and hospital use are included in traditional blood glucose meters. One unit includes the monitoring device only and not the test strips.

10.1.2.2 Blood Glucose Test Strips

Blood glucose test strips are the consumable components of traditional blood glucose meters. Glucose test strips contain chemicals that oxidize with the patient’s blood glucose to produce an electric current which is measured by the meter. One unit includes 50 glucose test strips.

10.1.2.3 Lancets

Lancets are used to prick the skin to obtain a small quantity of capillary blood for testing blood glucose using a glucose meter. These are usually used in combination with a lancing device (which holds the lancet firmly) and moves the lancet when triggered. One unit includes 25 lancets.

10.1.3 Insulin Delivery Devices

Insulin delivery devices are used to inject measured doses of insulin through the skin and into the fatty tissue below. Insulin delivery devices included in this market are syringes, pens and insulin pumps. Non-percutaneous delivery devices such as inhaled, buccal and ocular are not included in this category.

10.1.3.1 Insulin Pens

An insulin pen is a device that delivers measurable doses of insulin through the skin. A pen is comprised of disposable needles and an insulin cartridge. Insulin pens constitute disposable and reusable types.

Disposable Insulin Pens

Disposable insulin pens are pre-filled insulin devices and are disposed of after use. One insulin pen has been considered as one unit.

Pen Needles

Pen needles are used in conjunction with the insulin pens to deliver insulin into the body. A pen needle consists of a hollow needle which is embedded in a plastic hub which, in turn, attaches to the insulin pen. A pack of 100 needles per pack is considered as one unit.



Appendix

Reusable Insulin Pens

Reusable insulin pens are delivery devices that can be loaded with a cartridge of insulin and are reusable. First time purchase of the device includes one pen, needles and one cartridge. One unit consists of a pen, needle and an insulin cartridge. Subsequent purchase of insulin cartridges is not considered in this segment.

10.1.3.2 Insulin Pumps

An insulin pump is an insulin delivery device that administers programmed doses of insulin for diabetes management. The device consists of a battery-operated pump, an insulin reservoir and an infusion set with a tubing system for subcutaneous intervention. Traditional and disposable insulin pumps are tracked under insulin pumps.

Disposable Insulin Pumps

Disposable insulin pumps use microfluidic MEMS (Micro-Electro-Mechanical System) technology, which allows a tiny pump to be mounted on a disposable skin patch that can be replaced every two to three days to provide continuous insulin infusion. Personal Diabetes Managers (PDM) are not covered under this segment. One unit consists of a built-in blood glucose monitor and disposable skin patches with sensors.

Traditional Insulin Pumps

Traditional insulin pumps are programmable battery-powered pumps which deliver insulin through insulin infusion catheters. The traditional insulin pumps market does not include insulin reservoirs and infusion sets. One unit consists of one battery-powered pump.

10.1.3.3 Insulin Syringes

Insulin syringes are hypodermic needles attached to hollow barrels that are used to inject insulin. Insulin syringes come in several different sizes to match insulin strength and dosage. One unit of general insulin syringes consists of 100 syringes.

10.1.3.4 Traditional Insulin Pump Accessories

Traditional insulin pump accessories are the consumable items which are used in conjunction with the battery-powered pumps. One unit of traditional insulin pump accessories contains a disposable reservoir for storing insulin, a disposable infusion set, including a cannula for subcutaneous insertion, and a tubing system to interface the insulin reservoir to the cannula.

10.2 Acronyms

AADE: American Association of Diabetes Educators

ANAD: Associacao Nacional de Assistencia de Diabetico

APC: Artificial Pancreas Control Software

BD: Becton, Dickinson and Company

BGM: Blood Glucose Monitoring

CAGR: Compound Annual Growth Rate

CDC: Centers for Disease Control and Prevention

CDiC: Changing Diabetes in Children

CGM: Continuous Glucose Monitoring

CRDM: Cardiac Rhythm Disease Management

DKA: Diabetic ketoacidosis

DPCP: Diabetes Prevention and Control Programs

EFSD: European Foundation for the Study of Diabetes

FENAD: Federacao Nacional de Associacoes e Entitades de Diabetes

GDH-PQQ: Glucose Dehydrogenase-Pyrroloquinoline Quinone



Appendix

GSK: GlaxoSmithKline plc

HbA1c: Hemoglobin A1c

HCD: Health-Chem Diagnostics

IBL AG: International Brand Licensing AG

ICU: Intensive Care Unit

IDF: International Diabetes Federation

IR: Infra Red

ISPAD: International Society for Pediatric and Adolescent Diabetes

JAPI: Journal of the Association of Physicians of India

JDRF: Juvenile Diabetes Research Foundation Ltd

LGS: Low Glucose Suspend

LRL: Lilly Research Laboratories

M&A: Merger and Acquisition

MDI: Multiple Daily Injection

MEMS: Micro Electro Mechanical Systems

MPR: Monthly Prescribing Reference

NDEP: National Diabetes Education Program

NHS: National Health Service

NICE: National Institute for Health and Clinical Excellence

OAD: Oral Antidiabetics

PDM: Personal Diabetics Managers

PEC: Personal Ear Clip

PRC: People’s Republic of China

R&D: Research and Development

RDC: Roche Diabetes Care

SMBG: Self Monitoring of Blood Glucose

SOI: Silicon-on-Insulator

STS: Short-Term Sensor

UAB: University of Alabama at Birmingham

UHG: UnitedHealth Group

USB: Universal Serial Bus

WDF: World Diabetes Foundation

WHO: World Health Organization



Appendix

10.3 Sources

AADE (2008). Insulin Pump Therapy: Guidelines for Successful Outcomes. American Association of Diabetes Educators (2008). Available from http://www.diabeteseducator.org/export/sites/aade/_resources/pdf/Insulin_Pump_White_Paper.pdf [Accessed on May 29, 2012].

Bergenstal R, et al. (2010). Effectiveness of Sensor-Augmented Insulin-Pump Therapy in Type 1 Diabetes. New England Journal of Medicine; 363:4.

CDC (2011a). National diabetes fact sheet: national estimates and general information on diabetes and prediabetes in the United States. Available from http://www.cdc.gov/diabetes/pubs/pdf/ndfs_2011.pdf [Accessed on May 14, 2012].

CDC (2011b). Obesity and Overweight. Available from http://www.cdc.gov/nchs/fastats/overwt.htm/ [Accessed on May 14, 2012].

IDF (2009). Economic impact of Diabetes, 4th edition. Available from http://www.idf.org/sites/default/files/Economic_impact_of_Diabetes.pdf [Accessed on May 15, 2012].

IDF (2011). The Global Burden, 5th edition. Available from http://www.idf.org/diabetesatlas/5e/the-global-burden [Accessed on May 15, 2012].

IDF-Europe (2011). “The Policy Puzzle: Is Europe Making Progress?” 3rd edition, 2011. Available from http://ec.europa.eu/health/major_chronic_diseases/docs/policy_puzzle_2011.pdf [Accessed on May 14, 2012].

J.E. Shaw, et al. (2010). Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Research and Clinical Practice (2010). Available from http://blogimages.bloggen.be/diabetescheck/attach/35622.pdf [Accessed on May 28, 2012].

JAPI (2011). Jothydev Kesavadev. Continuous Insulin Infusion Systems in Type 2 Diabetes. Journal of the Association of Physicians of India; Volume 59.

JNJ (2011). Annual Report, 2011.

mims (2012). OptiClik, OptiPen and OptiSet insulin pens discontinued. Available from http://www.mims.co.uk/news/1110165/OptiClik-OptiPen-OptiSet-insulin-pens-discontinued/ [Accessed on May 18, 2012].

MPR (2009). Novolin insulin delivery devices to be discontinued. Available from http://www.empr.com/novolin-insulin-delivery-devices-to-be-discontinued/article/146607/ [Accessed on May 18, 2012].

NHS (2008). Insulin pump therapy for diabetes. Available from http://www.nice.org.uk/nicemedia/live/12014/41303/41303.pdf [Accessed on May 18, 2012].

Bayer (2012) via Reuters. Germany's Bayer considers diabetes device unit sale: report. Available from http://news.yahoo.com/germanys-bayer-considers-diabetes-device-unit-sale-report-051429706.html [Accessed on May 22, 2012].

Roche (2011). Annual Report, 2011.

Sanofi (2011). Annual Report, 2011.

UAB (2010). Reasons to Change to Insulin Pump. UAB School of Medicine. Available from http://medicine.uab.edu/Peds/54568/endo/80131/ [Accessed on May 25, 2012].

UHG (2010). The United States of Diabetes: Challenges and opportunities in the decade ahead. Available from http://www.unitedhealthgroup.com/hrm/unh_workingpaper5.pdf [Accessed on May 14, 2012].

WDF (2008; last updated in January 2011) China continues to create access to care. Available from http://www.worlddiabetesfoundation.org/composite-118.htm and http://www.worlddiabetesfoundation.org/composite-1925.htm [Accessed on May 28, 2012].



Appendix

WDF (2012). From budgets to patients - bridging the gap in Brazil. Available from http://www.worlddiabetesfoundation.org/composite-939.htm [Accessed on May 28, 2012].

10.4 Research Methodology

GBI Research’s dedicated research and analysis teams consist of experienced professionals in marketing and market research with consulting backgrounds in the medical devices industry and advanced statistical expertise.

GBI Research adheres to the codes of practice of the Market Research Society (www.mrs.org.uk) and the Strategic and Competitive Intelligence Professionals (www.scip.org).

All GBI Research databases are continuously updated and revised. The following research methodology is followed for all databases and reports.

10.4.1 Secondary Research

The research process begins with exhaustive secondary research on internal and external sources being carried out to source qualitative and quantitative information relating to each market.

The secondary research sources that are typically referred to include, but are not limited to:

Company websites, annual reports, financial reports, broker reports, investor presentations and SEC filings.

Industry trade journals, scientific journals and other technical literature.

Internal and external proprietary databases.

Relevant patent and regulatory databases.

National government documents, statistical databases and market reports.

Procedure registries.

News articles, press releases and web-casts specific to the companies operating in the market.

10.4.2 Primary Research

GBI Research conducts hundreds of primary interviews a year with industry participants and commentators in order to validate its data and analysis. A typical research interview fulfills the following functions:

It provides first-hand information on the market size, market trends, growth trends, competitive landscape and future outlook.

It helps in validating and strengthening the secondary research findings.

It further develops the analysis team’s expertise and market understanding.

Primary research involves email correspondence, telephone interviews and face-to-face interviews for each market, category, segment and sub-segment across geographies.

The participants who typically take part in such a process include, but are not limited to:

Industry participants: CEOs, VPs, marketing/product managers, market intelligence managers and national sales managers.

Hospital stores, laboratories, pharmacies, distributors and paramedics.

Outside experts: investment bankers, valuation experts, research analysts specializing in specific medical equipment markets.

Key opinion leaders: physicians and surgeons specializing in different therapeutic areas corresponding to different kinds of medical equipment.



Appendix

10.4.3 Models

Where no hard data is available GBI Research uses modeling and estimates in order to produce comprehensive data sets. The following rigorous methodology is adopted:

Available hard data is cross referenced with the following data types to produce estimates:

Demographic data: population, split by segment.

Macro-economic indicators: Gross Domestic Product, Inflation rate. .

Healthcare Indicators: health expenditure, physicians base, healthcare infrastructure and facilities.

Selected epidemiological and procedure statistics.

Data is then cross-checked by the expert panel.

All data and assumptions relating to modeling are stored and are available to clients on request.

10.4.4 Forecasts

GBI Research uses proprietary forecast models. The following four factors are utilized in the forecast models:

Historic growth rates.

Macro indicators such as population trends and healthcare spending.

Forecast epidemiological data.

Qualitative trend information and assumptions.

Data is then cross-checked by the expert panel.

All data and assumptions relating to modeling are stored and are available to clients on request.

10.4.5 Expert Panels

GBI Research uses a panel of experts to cross verify its databases and forecasts.

GBI Research’s expert panel comprises marketing managers, product specialists, international sales managers from medical device companies; academics from research universities, KOLs from hospitals, consultants from venture capital funds and distributors/suppliers of medical equipment and supplies.

Historic data and forecasts are relayed to GBI Research’s expert panel for feedback and adjusted in accordance with this feedback.



Appendix

10.6 Disclaimer

All Rights Reserved.

No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form by any means, electronic, mechanical, photocopying, recording or otherwise, without the prior permission of the publisher, GBI Research.

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