pathoPhy of Appendicitis
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Transcript of pathoPhy of Appendicitis
8/7/2019 pathoPhy of Appendicitis
http://slidepdf.com/reader/full/pathophy-of-appendicitis 1/2
Episodes of constipation Low fiber diet
Occlusion of appendix by
fecaloth
Decreased flow/ drainage of
Increased ILP in the appendix
Vasocongestion
Decreased blood supply in the appendix
Decreased oxgen supply in the appendix
Appendix starts to be necrotic; bacteria
invade the appendix
Start of the inflammatory process
Release of chemical mediators Activation of the vomiting
center in the medulla
Neutrophils to area
Histamine, prostaglandin,
leukotrienes, bradykinin
Swelling of appendix
Prostaglandin, bradykinin
Pain in the RLQ of
abdomen
Stimulation of vagus
nerve
Nausea & vomiting
Risk for deficient
fluid volume
Pus formation
(phagocytized
bacteria and dead
cells)
Risk for infection (if
appendix ruptures)
Inflammation of appendix
a endicitis
Acute ain
Interleukin-l
Increased WBC