Pathology Visions Conference

Giri Iyer

General Manager, Strategic Development

Integrated IT Solutions

10/22/2007

Digital Pathology

HCIT Visions – A GE Healthcare Perspective

3GE Healthcare IITS

July 24, 2007

A Tale of Two Cities…

Pre-Clinical Research

Clinical Care Delivery

Patient Safety: Need better Tox data earlier

Drug Efficacy: Need better biomarkers and ADME profiles

Patient Safety : Five Rights Checking

Drug Efficacy: Need better drugs

Clinical Trial Process

Drug Candidate Funnel weak

Drug Costs and Failure Rates

Lost in Translation: Need better data exchange earlier

4GE Healthcare IITS

July 24, 2007

From Quasi-quantitativeTo Dynamic Range

From Single Biomarker To Multiplexing

From Dx To enabling Rx

To DigitalFrom Glass

The Future of Anatomical Pathology

5GE Healthcare IITS

July 24, 2007

Market Adoption Projection

Rx adopting

first;AMCs for Research

only

Ref Labs driving clinical;

AMCs for Clinical

Main stream clinical

adoption

2008-2009

2009-2010

2010+ Time

Market Access

• Scan times

•Image Quality

•Latency

• FDA approval

•Workflow

•Algorithms

•Workflow

•ROI story

• TCO story

6GE Healthcare IITS

July 24, 2007

Key Drivers for Industry Success• Whole slide Imaging today.. In vivo

molecular imaging tomorrow

• Better standards for Interoperability…DICOM, Jpeg, HL7, CDISC, MIMIx?, MIAPE?

• FDA compliance vs speed-to-market trade-offs

• Better Data Exchange…Fusion between Medical Informatics and Bio Informatics

• Ultimate litmus test is Drug Efficacy that is concomitant with Patient Safety

7GE Healthcare IITS

July 24, 2007

GE HCIT Perspective • Industry evolution driven through image digitization

• When its about fast scan times and high resolution images.. GE is a usual suspect

• Industry definitions changing? Is it a PACS? Is it a LIS? Is it just the old Anatomic Pathology Module on new

steroids?

• Interoperability with existing systems is key to success

• Customer acceptance will depend upon transforming Pathology workflow with significant value added

• Thanks for having us here.. The youngest start-up in the market… much to learn