Pathogenesis of non-alcoholic fatty liver disease by J. K. Dowman, J.W. Tomlinson, and P.N. Newsome...

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Pathogenesis of non-alcoholic fatty liver disease by J. K. Dowman, J.W. Tomlinson, and P.N. Newsome QJM Volume ():hcp158 November 13, 2009 © 2009 The Author(s)

Transcript of Pathogenesis of non-alcoholic fatty liver disease by J. K. Dowman, J.W. Tomlinson, and P.N. Newsome...

Page 1: Pathogenesis of non-alcoholic fatty liver disease by J. K. Dowman, J.W. Tomlinson, and P.N. Newsome QJM Volume ():hcp158 November 13, 2009 © 2009 The Author(s)

Pathogenesis of non-alcoholic fatty liver disease

by J. K. Dowman, J.W. Tomlinson, and P.N. Newsome

QJMVolume ():hcp158

November 13, 2009

© 2009 The Author(s)

Page 2: Pathogenesis of non-alcoholic fatty liver disease by J. K. Dowman, J.W. Tomlinson, and P.N. Newsome QJM Volume ():hcp158 November 13, 2009 © 2009 The Author(s)

J. K. Dowman et al. QJM 2009;qjmed.hcp158

© 2009 The Author(s)

Page 3: Pathogenesis of non-alcoholic fatty liver disease by J. K. Dowman, J.W. Tomlinson, and P.N. Newsome QJM Volume ():hcp158 November 13, 2009 © 2009 The Author(s)

J. K. Dowman et al. QJM 2009;qjmed.hcp158

© 2009 The Author(s)

Page 4: Pathogenesis of non-alcoholic fatty liver disease by J. K. Dowman, J.W. Tomlinson, and P.N. Newsome QJM Volume ():hcp158 November 13, 2009 © 2009 The Author(s)

Mechanisms of hepatic fat accumulation.

J. K. Dowman et al. QJM 2009;qjmed.hcp158

© 2009 The Author(s)

Page 5: Pathogenesis of non-alcoholic fatty liver disease by J. K. Dowman, J.W. Tomlinson, and P.N. Newsome QJM Volume ():hcp158 November 13, 2009 © 2009 The Author(s)

Proposed pathogenesis of NASH. The likelihood of progression to advanced NASH/cirrhosis results from a complex interplay between genetic predisposition and the mechanisms described

earlier.

J. K. Dowman et al. QJM 2009;qjmed.hcp158

© 2009 The Author(s)


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