Path Review 1

7/25/2019 Path Review 1

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PathologyReview 1: Cell Injury, Death,

and Adaptation I,II,III

Andrew Mason

andrew.masontu!ts.edu


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"ips !or this #ourse:

$ %o#us on the le#tures, i! possi&le wat#h

them multiple times

$ "he hardest part is organi'ing the

in!ormation in your &rain

$ I! you don(t understand something, use

the internet

$ D) *)" overanaly'e the test +uestions


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Dis#laimer:

$ "he review slides may not in#lude

everything you need to now !or the

test.$ %o#us on the learning the main points,

then add details later.

$ -e did not have images on the testslast year, &ut this year you might.


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$ iopsy: removal o! tissue !or

mi#ros#opi# e/amination, e.g. needle

0!luid, pun#h, #one

$ Cytology: use mi#ros#ope to e/amine

#hanges in individual or small groups o!

#ells to D/ disease, e.g. pap smear,

thora#entesis 0pleural !luid


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Disease 2 #ellular rea#tion to

injury, i.e. adaptation or !ailureto adapt 0R. 3ir#how


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CellAdaptations


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4ypertrophy

$ In#rease in si'e 0not in#rease in

num&er

$ Physiologi#: e.g. seletal mus#les 0no

#ell division

$ Pathologi#: e.g. #ardia# myo#ytes

$ 5uellular: e.g. 6R


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-hi#h o! the !ollowing

#hanges is #hara#teristi# o!

hypertrophy7

a In#reased protein degradation

& In#reased protein synthesis

# In#reased protein degradation and

in#reased protein synthesis

d De#reased protein degradation andin#reased protein synthesis


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-hi#h o! the !ollowing

#hanges is #hara#teristi# o!

hypertrophy7

a In#reased protein degradation

& In#reased protein synthesis

# In#reased protein degradation and

in#reased protein synthesis

d De#reased protein degradation andin#reased protein synthesis


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8imitations o! hypertrophy as

adaptive me#hanism:$ Mus#le growth plateaus: 9somehow

you don(t loo lie Mr. ;niverse

Path Review 1

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