parsley is not amenable to forward genetics
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parsley is not amenable to forward genetics
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parsley is not amenable to forward genetics. NHL25. NHL3. Innate immunity – A common theme in mammals, Drosophila and plants (1). Pathogen-associated molecular patterns (PAMP) are recognized by pattern. recognition receptors and trigger expression of immune response genes - PowerPoint PPT Presentation
Transcript of parsley is not amenable to forward genetics
parsley is not amenable to forward genetics
NHL3
NHL25
Innate immunity – A common theme in mammals,Drosophila and plants (1)
Pathogen-associated molecular patterns (PAMP) are recognized by patternrecognition receptors and trigger expression of immune response genes(Medzhitov, R & Janeway, CA (1997) Cell 91:295-8)
LPS from gram-negative bacteriaPGN from gram-positive bacteriaFungal glucans, chitin, proteins
Eubacterial flagellin
(often) abundant structuresSurface-exposed structures
Not present in hostsEvolutionarily conserved
Crucial to the biology of the pathogen
Institut of plant biochemistry
Institute of Plant Biochemistry
Innate immunity – A common theme in mammals,Drosophila and plants (2)
AcknowledgementJustin LeeAnnette RomanskiGuido FellbrichMagdalena Krzymowska
Anne Varet
Sabine RosahlCarola Geiler
Thorsten Nürnberger
Dierk Scheel
Collaborations:
Sakari Kauppinen (Novo Nordisk A/S, Denmark)Grethe RasmussenFrancine Govers (University of Wageningen, The Netherlands)Jürg Felix (FMI Basel, Switzerland)Jeff Dangl (University of North Carolina, USA)KWS Einbeck, Germany
Institute of Plant Biochemistry
