Parental Haemoglobin
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Transcript of Parental Haemoglobin
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EFFECT OF MATERNAL HAEMOGLOBIN VARIANT
ON PRE-WEANING GROWTH RATE OF SELECTEDBREEDS OF NIGERIAN SHEEP
Iyiola-Tunji, A.O.
Ahmadu Bello University,
Zaria, Nigeria
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Introduction Nigerian sheep breeds and their productive
potentials - Adu and Ngere (1979).
Limited attempts at improvement of Nigerian sheep
breeds.
Localized rearing of sheep in ecological zones
Osinowo and Adu, 1985.
Sheep breed characteristics and agro-ecologicical
location.
Sheep improvement through crossbreeding.
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Introduction Contd
Some adaptive and productive traits in sheep had
been linked to some variants of blood proteins.
Electrophoretic study of sheep haemoglobin types
showed that there are three main genotypes, which
are HbAA, HbBB and HbAB.
Variants of haemoglobin as genetic markers forselection of superior animals as parent of thenext generation.
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Objective of the study
This study was aimed at evaluating the
effect of maternal haemoglobin variant on
the pre-weaning growth rate of lambs in a
diallel crossbreeding involving Yankasa,
Uda and Balami.
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Materials and methods
Study location.
Sheep breed used.
Breeding pattern. Sire breed Dam breed
Yankasa Yankasa
Uda Uda
Balami Balami
Yankasa Uda
Yankasa Balami
Uda Yankasa
Uda Balami
Balami Yankasa
Balami Uda
Table 1: Diallel breeding pattern
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Materials and methods Contd
All lambs were singles.
Lambs identification.
Lambs weighed at birth and 2 weeks interval.
Statistical analysis- GLM Proc (SAS, 2003);
- Chi Square Proc.
Blood sample collection
Biochemical analysis of blood samples.
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Materials and methods Contd
Blood sample collection.
Sample analysis using cellulose acetate
electrophoresis.
B
A
Figure 1: Electrophoregram of haemoglobin variants
Anode
Cathode
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Results and discussion
Genotype frequency
Dam Hb Frequency Percent Sire Hb Frequency
AA 40 32.0 AA 0
BB 10 8.0 BB 0
AB 75 60.0 AB 10
Gene frequency
Dam Sire
A 0.62 A 50.0
B 0.38 B 50.0Hb = Haemoglobin; X2 = 50.8, P
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Allele A had the highest frequency (62%) in the
dam population.
This was in agreement with the report of
Akinyemi (2010) on Hb frequencies from similarbreeds of sheep.
Evans et al. (1958) had earlier suggested that
HbA has a selective advantage at higheraltitudes because it constitutes the mostcommon allele in highlands breeds of sheep.
Results and discussion Contd
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Contrastly, Salako et al. (2007) reported a higherfrequency of HbB in population of West AfricanDwarf sheep at low altitude in South-WestNigeria.
Results and discussion Contd
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Results and discussion Contd
Dam haemoglobin
Lamb genotype A B AB Total
YK X YK 15 (50.0) 5 (16.7) 10 (33.3) 30
UD X UD 0 (0.0) 0 (0.0) 10 (100.0) 10
BL X BL 0 (0.0) 2 (16.7) 10 (83.3) 12
YK X UD 10 (50.0) 0 (0.0) 10 (50.0) 20
YK X BL 0 (0.0) 0 (0.0) 5 (100.0) 5
UD X YK 0 (0.0) 0 (0.0) 10 (100.0) 10
UD X BL 10 (55.6) 3 (16.7) 5 (27.8) 18
BL X YK 5 (33.3) 0 (0.0) 10 (66.7) 15
BL X UD 0 (0.0) 0 (0.0) 5 (100.0) 5
Table 3: Cross-tabulation of lamb genotype by dam haemoglobin variant
Figures in parenthesis are expression of frequencies in percentages
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Dam haemoglobin variant
Trait AA BB AB Overall mean
GLT (days) 153.250.51b 153.900.89 b 152.200.28a 152.670.28
BWT (kg) 2.910.09 b 3.340.16 a 3.010.05 a 3.000.06
2WT (kg) 4.660.16 b 5.270.27 a 5.290.09 a 5.090.09
4WT (kg) 5.690.19 b 6.560.34 a 6.430.11 a 6.210.11
6WT (kg) 6.210.21 b 7.140.37 a 7.200.12 a 6.880.12
8WT (kg) 7.010.24 b 7.850.42 a 8.070.14 a 7.720.14
10WT (kg) 7.690.22 b 8.710.47 a 8.860.15 a 8.470.15
12WT (kg) 7.960.30 b 8.850.52 a 9.300.17 a 8.830.16abMeans across rows with different superscripts are significantly different (P
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Results and discussion Contd
The heterozygous form of haemoglobin (HbAB)in the population was probably more adapted tothe semi-arid condition of the study area than thehomozygous form HbAA.
This is clearly seen in better performance(in terms of pre-weaning growth rate) of the lamband the abundance of the genotype (HbAB) inthe population.
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Results and discussion Contd
Gootwine (1988) corroborated the result of thisstudy.
He stated that HbAB genonotype showed asignificant advantage over the other genotypesin both lamb and milk production.
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Conclusion
Haemoglobin genotype AB (HbAB) was thepredominant variant in the sheep population inNAPRI, Zaria, Nigeria.
HbAB dams had reduced gestation length andproduced lambs that performed outstandinglybetter than HbAA dams.
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Recommendation
The shorter gestation length and faster lambgrowth recorded for dams with HbAB should beconsidered and used in selection for a reduced
gestation length and improved growth rate oflambs in the population.
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