Ovarian stimulation strategies:Nurturing efficiency in ART9 December 2017 - Dubai, United Arab Emirates

REGIONAL WORKSHOP

FINAL PROGRAMME

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GENERAL INFORMATION

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CME Provider EXCEMED is a non profit foundation dedicated, since the last four decades, to the development ofhigh-quality medical education programmes all over the world.

EXCEMED adheres to the guidelines and standards of the European Accreditation Council forContinuing Medical Education (EACCME®) which states that continuing medical education must be balanced, independent, objective and scientifically rigorous.

EXCEMED adheres to the principles of the Good CME Practice group (gCMEp).

OverviewSuccess rates following IVF treatment have increased significantly since the early days, mainly contributed by the introduction and use of ovarian stimulation. Controlled ovarian stimulation (COS) has a vital role in IVF by allowing control of the various events and increasing the number of oocytes to optimise outcomes. The aim of COS is to achieve maximal success with minimal side effects. Other important aspects to be considered are cost-effectiveness and patient compliance. Progress in or understandings of ovarian physiology and new advances in ovarian stimulation strategies have made it possible to achieve the best outcomes with COS. The aim of this workshop is to lay out ideal outcomes desired by patients, embryologists, clinicians following (ART) and fine-tuned, individualised approaches towards attaining these goals.

Learning objectivesBy attending this live educational workshop, participants will be able to: • Define laboratory and clinical outcomes for defining success in ART• Key factors influencing the success of ART• Tailor the best stimulation protocol for patient undergoing ART• Discuss and debate changing approaches to ART

Target audienceThis programme is designed for clinicians and biologists working in assisted reproductive medicine, who want to acquire up-to date information for improving their current practice.

ChairRobert FischerFertility Centre HamburgHamburg, Germany

Ovarian stimulation strategies: Nurturing efficiency in ART

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VenueThis live educational workshop will take place at the:Le Méridien Dubai Hotel & Conference CentreAirport Road, PO Box 10001Dubai, United Arab Emirates

LanguageThe official language of this live educational course is English.

CME ProviderEXCEMED - Excellence in Medical Education

Senior Programme Manager: Chloé XilinasT +39 06 420413 505 - F +39 06 420413 677chloe.xilinas@excemed.org

Medical Advisor: Sesh Kamal Sunkara

For any logistic inquiry, please contact

Meridiano Congress InternationalEvent Manager: Giorgia Di EgidioT +39 06 88 595 209 - F +39 06 88595 234giorgia.diegidio@meridiano.it

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FACULTY

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Salem El ShawarbyUK Consultant & Subspecialist in Reproductive MedicineDirector of Corniche Fertility CentreCorniche HospitalAbu Dhabi, UAE

Robert FischerFertility Centre HamburgHamburg, Germany

Sesh Kamal SunkaraReproductive Medicine UnitQueen’s HospitalEssex, UK

Filippo Maria UbaldiG.EN.E.R.A Centre for Reproductive MedicineRome, Italy

Faculty

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PROGRAMME

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08.30 Registration

09.00 Opening and introduction R. Fischer (Germany)

Session I Fine tuning COS

Chair: R. Fischer (Germany) 09.10 L1: What is success in ART? (Laboratory and clinical outcomes for defining success in ART) F.M. Ubaldi (Italy)

09.35 L2: Number of oocytes for optimising IVF outcomes S.K. Sunkara (UK)

10.00 L3: Female age, ovarian reserve and ovarian reserve tests: implications for ART F.M. Ubaldi (Italy)

10.25 Panel discussion

11.05 Coffee break

11.25 L4: What kind of gonadotropins to use? S. El Shawarby (United Arab Emirates)

11.50 L5: Ovarian response groups, suboptimal response and The POSEIDON concept S.K. Sunkara (UK)

12.15 L6: Stimulation strategies for overcoming impaired response S. El Shawarby (United Arab Emirates)

12.40 Panel discussion

13.20 Lunch

Saturday, 9 December 2017

Session II Current debates in ART

Chair: R. Fischer (Germany)

14.20 L7: Is there a place for mild stimulation and modifying natural cycle in ICOS? F.M. Ubaldi (Italy)

14.45 L8: Is the time ready for all freeze strategy for all patients? S.K. Sunkara (UK)

15.10 Panel discussion

15.40 Coffee break

16.00 Two interactive case studies S.K. Sunkara (UK) S. El Shawarby (United Arab Emirates) 16.55 Concluding remarks R. Fischer (Germany)

17.00 End of the workshop

Legend

L : Lecture : Interactive case studies : Panel discussion

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EXCEMED adheres to guidelines of the European Accreditation Council for Continuing Medical Education (EACCME®) and all other professional organizations, as applicable, which state that programmes awarding continuing education credits must be balanced, independent, objective and scientifically rigorous. Investigative and other uses for pharmaceutical agents, medical devices and other products (other than those uses indicated in approved product labeling/package insert for the product) may be presented in the programme (which may reflect clinical experience, the professional literature or other clinical sources known to the presenter). We ask all presenters to provide participants with information about relationships with pharmaceutical or medical equipment companies that may have relevance to their lectures. This policy is not intended to exclude faculty who have relationships with such companies; it is only intended to inform participants of any potential conflicts so that participants may form their own judgements, based on full disclosure of the facts. Further, all opinions and recommendations presented during the programme and all programme-related materials neither imply an endorsement nor arecommendation on the part of EXCEMED. All presentations represent solely the independent views of the presenters/authors.

The following faculty provided information regarding significant commercial relationships and/ordiscussions of investigational or non-EMEA/FDA approved (off-label) uses of drugs:

Salem El Shawarby Declared no potential conflict of interest.

Robert Fischer Declared no potential conflict of interest.

Sesh Kamal Sunkara Declared receipt of honoraria or consultation fees from Merck and Ferring. Participation in a company sponsored speaker’s bureau Merck Europe, Ferring UK, MSD.

Filippo Maria Ubaldi Declared receipt of grants from Merck (GFI) and Finox and receipt of honoraria or consultation fees from Merck, MSD, Ferring, Cook, EXCEMED.

Stakeholder of Genera Health Care Srl and Flam Srl.

Faculty disclosures

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BIOGRAPHIES

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Robert Fischer

Fertility Centre HamburgHamburg, Germany

Robert Fischer is founder and Medical Director of the IVF unit at the Fertility Center Hamburg - one of Germany’s largest and leading IVF centres. In July 1998 the Fertility Center Hamburg was one of the first centres inGermany, and worldwide, to introduce certified quality management according to the ISO 9001. In 2002, the IVF laboratory became ISO 17025 certified. Prior to these developments, in 1983 he pioneered and was medical director ofthe first outpatient IVF unit in Hamburg. Authorof numerous publications in national and international scientific journals and books, as wellas lecturer at conferences worldwide, he is also an active member of the American Society of Reproductive Medicine, founding member of the European Society of Human Reproduction and past member of its advisory committee as well as founding member of the German reproductive organisations, “AG Gynäkologische Endokrinologie und Fortpflanzungsmedizin” and “Berufsverband Reproduktionsmedizinischer Zentren”.

Salem El Shawarby

UK Consultant & Subspecialist in Reproductive MedicineDirector of Corniche Fertility CentreCorniche HospitalAbu Dhabi, UAE

Salem El Shawarby is a Consultant in Reproductive Medicine and is the Director of the Corniche Fertility Centre at the reputable Corniche Hospital (the largest and longest established Government maternity hospital in UAE) since September 2014. Prior to moving to UAE, Dr. El Shawarby was a Consultant in Reproductive Medicine & Surgery in the UK at the world renowned IVF Hammersmith; the IVF unit of the Hammersmith, Queen Charlotte’s & Chelsea Hospitals, Imperial College London. He also ran his own private clinic at the prestigious Harley Street, where he used to treat patients from both the UK, as well as overseas patients from different parts of the world. He has over 23 years of experience in the field of Reproductive Medicine, having worked in 5 Assisted Conception units of some of the UK’s leading University hospitals. He started his career in Reproductive medicine by obtaining a clinical research fellowship at IVF Hammersmith. He then became a RCOG Accredited Subspecialist in Reproductive Medicine & Surgery after completing a Subspecialty training fellowship at the IVF unit of University College London Hospital/Centre for Reproductive & Genetic Health.

He has also previously worked at the IVF units of Guy’s and St. Thomas’ Hospital, and the University Hospitals of Leicester & Southampton. Dr. El Shawarby graduated from Cairo University- Egypt (MBBCh) with Honours in 1994, where he then obtained MSc & MD in Reproductive Medicine in 1998 and 2002 respectively, and he also holds a professor position in Obstetrics & Gynaecology in the same university. He was admitted as a member of the Royal College of Obstetricians & Gynaecologists in London in 2000, and was granted the college’s fellowship in 2017. He is also a member of the RCOG Reproductive Medicine Clinical Studies Group and the British Fertility Society. Dr. El Shawarby is the author of more than 30 peer-reviewed papers published in top medical journals in the field of Reproductive Medicine. He has presented at several national and international conferences and meetings. His current clinical and research interests include: ovarian reserve tests, assisted conception, optimizing ovarian stimulation protocols and the outcome of IVF, recurrent implantation failure, and reproductive surgery.

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Filippo Maria Ubaldi

G.EN.E.R.A Centre for Reproductive MedicineRome, Italy

Filippo Maria Ubaldi is Medical Doctor, Clinical Director at the GENERA Centres for Reproductive Medicine in Rome, Marostica, Umbertide and Naples, Italy. With academic degrees in Obstetrics and Gynaecology, Masters in Andrology and Reproductive Medicine, he is also intensely dedicated to educational, editorial and practitioner activities. Co-author of 8 books on Reproductive Medicine and Co-author of 8 books on the topic of Reproductive Medicine and of 118 peer reviewed journals; author H-index is 38. Editor of the treaty on Reproductive Medicine ‘Medicina della Riproduzione Umana’ published in Italy in 2010. Invited as speaker at over 300 National and International congresses on the topic of Reproductive Medicine and has been Scientific Coordinator of more than 30 congresses and courses. Member of the ESHRE Executive Committee during 2005-2009, he has been Chairman of the 26th ESHRE Annual Meeting held in Rome in June 2010. In 2014 received the

Italian National Scientific License as full Professor in Obstetrics and Gynaecology. During 2014-2015 has been member of the technical advisory board established by the Ministry of Health on heterologous fertilization.

Sesh Kamal Sunkara

Reproductive Medicine UnitQueen’s HospitalEssex, UK

Sesh Kamal Sunkara is a Consultant Gynaecologist and Subspecialist in Reproductive Medicine and Surgery.She specialised in the field of Obstetrics and Gynaecology and is a Member of the Royal College of Obstetricians and Gynaecologists (MRCOG), UK. She undertook translational research in Reproductive Medicine at the Assisted Conception Unit, Guy’s and StThomas’ NHS Foundation Trust and King’s College London which formed the basis forher Research degree in Reproductive Medicine; Doctor of Medicine (MD) awarded by King’s College London. She has dual accreditation with the UK General Medical Council as a specialist in Obstetrics and Gynaecology as well as Reproductive Medicine. She worked as a Consultant gynaecologist and Subspecialist in Reproductive Medicine at the Aberdeen Fertility Centre, University of Aberdeen before moving to Barking Havering and Redbridge University Hospitals to set up anew IVF service. In addition to her clinical work, she has published in the field of Reproductive Medicine and authored severalbook chapters. She has organised

and participated in several national and international symposia and workshops in thefield of Reproductive Medicine. She is the Associate Editor for Human Reproduction Journalby the European Society of Human Reproduction and Embryology (ESHRE). She is on the executive board for the RCOG – Reproductive Medicine Clinical Studies Group which is actively involved in supporting multi-centre research studies in the UK.

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All EXCEMED programmes are organized solely to promote the exchange and dissemination of scientific and medical information. No forms of promotional activities are permitted. There may be presentations discussing investigational uses of various products. These views are the responsibility of the named speakers, and do not represent an endorsement or recommendation on the part of EXCEMED. This independent programme is made possible thanks to educational grants received from: Ferty School, MVZ Fertility Center Hamburg, Istituto di Ricerche Genetiche, Merck KGaA Darmstadt Germany and San Raffaele Hospital Milan.

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