Our secret for your radiant skin - Lubex anti-ageThe anti-aging effect on the skin has been ......
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Our secret for your radiant skin www.lubexantiage.ch innovation & expertise in dermatology
Transcript of Our secret for your radiant skin - Lubex anti-ageThe anti-aging effect on the skin has been ......
Our secret for your
radiant skin
www.lubexantiage.ch
innovation & expertise in dermatology
2
Contents
Page
4 Our ambassadors for Lubex anti-age®
7 40 years of dermatological competence
8 Own research and development as well as GMP-compliant manufacturing
10 Lubex anti-age® – together against breast cancer
12 Prevention of skin aging
13 Airless dispenser packaging for high-quality formulations
14 3 skin-specific active day and night treatment lines: light, classic, rich
16 Lubex anti-age® light Active day and night treatment
20 Lubex anti-age® classic Active day and night treatment
24 Lubex anti-age® rich Active day and night treatment
3
Permamed supports the breast cancer prevention programme of the Swiss Can- cer League with one Swiss franc for each package of Lubex anti-age® sold.
United against breast cancer28 Lubex anti-age®
Specific skin treatment
30 Overview of specific skin treatment products 32 Lubex anti-age® serum 33 Lubex anti-age® hyaluron 4 types NEW 34 Lubex anti-age® intelligence 35 Lubex anti-age® vitamin C NEW STUDY
36 Around the eyes Lubex anti-age® eye intensive | Lubex anti-age® eye pads
38 For silky-soft skin Lubex anti-age® hydration oil NEW STUDY
39 UV A+B all-round skin protection Lubex anti-age® sun fluid face SPF 50 NEW
40 Lubex anti-age® dermatological cleansing and refreshing Lubex anti-age® cleansing milk | Lubex anti-age® tonic
42 Lubex anti-age® professional active skin treatment regimen in 7 steps
44 Clinical Lubex anti-age® studies
50 Lubex anti-age® – with dermatologically approved ingredients
52 For skin and hair – additional dermatological Lubex line extension products (OTC)
56 Our Internet and social media presence
Lubex anti-age® products are available in Switzerland at your pharmacy or drugstore and online.
4
More and more people rightly place high demands on the quality of their
daily-used skincare products and gladly rely on the expert advice from specialist doctors and pharmacists.
The aging processes of the skin are not only due to genetics, but are also pro-moted by oxidative stress (UV radiation, environ mental pollutants, smoking, etc.).
Over the years this will result in visible and perceptible signs of skin aging: dryness, thinning of the skin, wrinkles and pigment irregularities.
Prof. Dr. med. Monica Gericke
Plastic face surgeon Faceclinic, Zurich
«The aging processes of the skin are not only due to genetics»
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«You will immediately feel the difference and see the result»
«The optimum combination of high doses of active ingredients and pleasant textures convinces me»
The optimum combination of high dos-es of active ingredients and pleasant
textures convinces me of the Lubex anti-age® products.
The anti-aging effect on the skin has been proved in clinical studies carried out in collaboration with dermatologists. Ani-mal trials are dispensed with at both the develop ment and testing stages.
All Lubex anti-age® products are deliber-ately developed without colour additives, allergenic perfumes, preservatives and paraffin oil, so they are also suitable for sensitive skin.
Dr. med. Kerstin Haufe
Dermatologist Practice dermamedica
Schwyz
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As a dermatologist, I recommend Lubex anti-age® products in my practice be-
cause of their high efficacy, good tolerability and positive results.
To define your ideal skincare programme, you should consult a specialized retailer. Lubex anti-age® is exclusively available from trained experts in pharmacies, drug-stores and doctors’ practices to ensure clients receive comprehensive advice and achieve an optimal result.
Dr. med. Ursula Gansser
Dermatologist Practice Cosmodermis Einsiedeln
«The focus is on the specific needs of your skin»
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AllLubex anti-age®products are:
• suitable for sensitive skin
• developed with dermatologists
• clinically tested
• free from preservatives
• free from allergenic perfumes
• free from colour additives and paraffin oil
• without animal experiments
40 years of dermatological competenceinnovation & expertise
in dermatology
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Own research and development as well as GMP-compliant manufacturing
Permamed is one of Switzerland’s lead-ing pharmaceutical companies in the
field of dermatology. The company’s inno-vative pharmaceutical and dermatological preparations have been successfully es-tablished in the market, with doctors and with specialized retailers for over 40 years.
For about 10 years, Permamed has also made use of its dermatological compe-tence in the development of the dermato-logical line Lubex anti-age®.
The efficacy of our Lubex anti-age® pro-ducts has been scientifically proven in clinical trials. Lubex anti-age® acts from the surface of the skin down to the lower layers and protects the skin from prema-ture aging.
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All Lubex anti-age® products are being developed in our own research department and are then being manufactured according to GMP standards.
Skin analysis and consulting
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Lubex anti-age® together against breast cancer
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Permamed supports the Swiss Cancer League. Every time a Lubex anti-age®
product is sold, we donate one Swiss franc to the Swiss Cancer League for breast cancer prevention measures.
Lubex anti-age® is primarily used and ap-preciated by female clients, so we want to give them something back by sponsoring the Swiss Cancer League.
Permamed supports the breast cancer prevention programme of the Swiss Can- cer League with one Swiss franc for each package of Lubex anti-age® sold.
United against breast cancer
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20 30 40 50 60 70 80 Age
Skin
agi
ng
Lube
x anti
-age
® comb
ats sk
in ag
ing
Delayed skin aging through use of Lubex anti-age®
Average skin aging
Accelerated skin aging
mar
ked
av
erag
e sl
ight
St
art
x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
* modified according to Wolf A., Hausarzt 2005
Prevention of skin aging
As early as 20 years of age, our skin begins to age because it is subject to both, the biological and the environment-induced aging processes.
Lubex anti-age® is a very efficient meas-ure to combat premature aging but cannot completely halt the process.* Lubex anti-age® enhances and refreshes the skin’s appearance and allows the skin to shine.
Care and pamper your skin with Lubex anti-age® specific skin treatment. The sooner you start, the better: your skin stays young for longer and radiantly fresh.
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«Airless»- pump
Cream
Plunger
«Airless»- pump
Serum
Inner sac
The deployment of innovative airless dispenser-style packaging allows
• high-quality active ingredients to be protected from light and oxygen,• their effect is optimally sustained, • the addition of skin-stressing preservatives can be omitted.
Airless dispenser packaging for high-quality formulations
3 skin-specific active day and night treatment lines: light, classic, rich
day light night light
for normal to slightly oily skin and combination skin
young ager 20+
day classic night classic
for normal to slightly dry skin for normal to slightly dry skin
middle ager 35+ middle ager 35+
day rich night rich
for dry to very dry and/or mature skin
best ager 50+
Lubex anti-age®
daylightUV 15
Lubex anti-age®
nightlightLubex anti-age®
dayclassicLubex anti-age®
dayclassicUV 10
Lubex anti-age®
dayclassicUV 30
Lubex anti-age®
nightclassicLubex anti-age®
dayrichLubex anti-age®
dayrichUV 20
Lubex anti-age®
nightrich
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Apply to the face, neck and décolleté and massage in gently, mornings or evenings after cleansing.
day light night light
for normal to slightly oily skin and combination skin
young ager 20+
day classic night classic
for normal to slightly dry skin for normal to slightly dry skin
middle ager 35+ middle ager 35+
day rich night rich
for dry to very dry and/or mature skin
best ager 50+
Lubex anti-age®
daylightUV 15
Lubex anti-age®
nightlightLubex anti-age®
dayclassicLubex anti-age®
dayclassicUV 10
Lubex anti-age®
dayclassicUV 30
Lubex anti-age®
nightclassicLubex anti-age®
dayrichLubex anti-age®
dayrichUV 20
Lubex anti-age®
nightrich
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Lubex anti-age® products are available in Switzerland at your pharmacy, drugstore and online.
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Lubex anti-age®light Active day and night treatment
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Lubex anti-age® light products are suitable for younger, normal to slight-ly oily skin and for combination skin.
• low content of lipids
• high content of moisturizers
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Lubexanti-age®day light
• hydrates the skin and cushions it from inside out
• increases the skin elasticity and prevents the formation of wrinkles
• protects against free radicals
• with UV filter SPF 15• with hyaluronates and
HAF (hyaluronic acid fragments)• with ectoine®
• with hexapeptides• with microalgae extract• with provitamins C + E
Lubexanti-age® light Active day and night treatment
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Lubexanti-age®night light
• prevents the formation of wrinkles • hydrates the skin intensively• protects against free radicals
• with ectoine®
• with biochromones• with coenzyme Q10• with hyaluronates• with ceramides
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Lubex anti-age®classic Active day and night treatment
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Lubex anti-age® classic products are suitable for normal to slightly dry skin at middle-age maturity.
• medium content of lipids
• high content of moisturizers
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Lubexanti-age®day classic
• tightens the skin by collagen building• smoothes expression lines • hydrates sustainably and makes the skin supple
• with highly effective peptides and dipeptide complex
• with hyaluronates and HAF (hyaluronic acid fragments)
Lubexanti-age®day classic UV 10
• additionally with 100 % mineral UV filter SPF 10
Lubexanti-age®classic Active day and night treatment
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Lubexanti-age® day classic UV 30
• effectively reduces fine wrinkles• tightens the skin by collagen building• increases the resistance of the skin against
environmental stress factors• protects actively during 24 h against free radicals
• with UV filter SPF 30• with highly effective peptides• with ectoine® and AntiOx system• with niacinamides
Lubexanti-age®night classic
• reduces wrinkling effectively, builds up the skin from within and repairs skin damage
• hydrates sustainably and increases the skin’s resistance• fights free radicals and premature skin aging
• with stabilised retinol 1900 IU / g• with provitamins C + E and coenzyme Q10• with ceramides
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Lubex anti-age® rich Active day and night treatment
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Lubex anti-age® rich products are suitable for dry to very dry skin and/or for mature skin.
• high content of lipids
• very high content of moisturizers
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Lubexanti-age®day rich
• reduces wrinkles • hydrates sustainably and makes the skin
more elastic• improves the skin structure and
plumps up wrinkles from the inside• keeps the skin vibrant • protects actively during 24 h against free radicals
• with highly effective peptides• with AntiOx system• with soy isoflavone liposomes• with apple stem cells• with HAF (hyaluronic acid fragments)
Lubexanti-age®day rich UV 20
• additionally with UV filter SPF 20
Lubexanti-age®rich Active day and night treatment
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Lubexanti-age®night rich
• reduces wrinkles noticeably and leads to a sustained lifting effect
• regenerates the skin and repairs skin damages • hydrates sustainably and makes the skin more elastic
• with high-dosed retinol 5000 IU / g• with hyaluronates, HAF (hyaluronic acid
fragments) and ceramides• with soy isoflavone liposomes• with AntiOx system
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Lubex anti-age® Specific skin treatment
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Lubex anti-age®
specific skin treatment products
are suitable for all skin types.
• as a complement to the active day and night treatment
• excellent for combining
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Special skin treatment products Hydration oil Active eyes contour treatment
UV A+B protection Cleansing and refreshing
combination of highly concen-trated active ingredients
page 32 page 33 page 34 page 35 page 38 page 36 page 37 page 39 page 41
Lubex anti-age®
serumanti-wrinkle serum
Lubex anti-age®
hyaluron 4 typesintensive booster
Lubex anti-age®
intelligencerefining & correcting
biostimulator
Lubex anti-age®
vitamin Cdepigmenting concentrate
Lubex anti-age®
hydration oilblack orchid
Lubex anti-age®
eye intensive intensive firming
Lubex anti-age®
eye padsanti-wrinkle &
skin-stress control
Lubex anti-age®
sun fluid face100 % mineral
SPF 50
Lubex anti-age®
cleansing milkclarifying,
antioxidant
Lubex anti-age®
tonic refreshing, hydrating
NEW
Overview of specific skin treatment products
Always apply Lubex anti-age® specific skin treatment products before active day or night treatment.
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Special skin treatment products Hydration oil Active eyes contour treatment
UV A+B protection Cleansing and refreshing
combination of highly concen-trated active ingredients
page 32 page 33 page 34 page 35 page 38 page 36 page 37 page 39 page 41
Lubex anti-age®
serumanti-wrinkle serum
Lubex anti-age®
hyaluron 4 typesintensive booster
Lubex anti-age®
intelligencerefining & correcting
biostimulator
Lubex anti-age®
vitamin Cdepigmenting concentrate
Lubex anti-age®
hydration oilblack orchid
Lubex anti-age®
eye intensive intensive firming
Lubex anti-age®
eye padsanti-wrinkle &
skin-stress control
Lubex anti-age®
sun fluid face100 % mineral
SPF 50
Lubex anti-age®
cleansing milkclarifying,
antioxidant
Lubex anti-age®
tonic refreshing, hydrating
NEW NEW
Lubex anti-age® products are available in Switzerland at your pharmacy, drugstore and online.
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Lubexanti-age®specific skin treatment Special skin treatment products
Lubexanti-age®serum anti-wrinkle serum
• reduces age wrinkles and acts against expression lines
• hydrates intensively• acts against oxidative stress and
increases the skin’s resistance
• with resveratrol• with penta- and hexapeptides• with biochromones• with vitamin C glucoside• with ectoine and with
HAF (hyaluronic acid fragments)
NEW
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Lubex anti-age® hyaluron 4 types intensive booster
• hydrates with 4-fold intensity from the surface into the lower layers and replenishes the skin’s moisture reserves
• noticeably plumps up wrinkles and tightens the skin
• acts as an antioxidant and protects against skin aging
• with 4 highly active hyaluron ingredients• with tripeptides• with provitamin C + vitamin E• with coenzyme Q10
Lubex anti-age® hyaluron 4 types replenishes the skin’s moisture reserves from the surface into the deeper layers with 4 different types of hyaluron agents.
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Intelligent active system with 6 biostimulators
Lubexanti-age®intelligence refining & correcting biostimulator
The 6 biostimulators in Lubex anti-age intelligence recognise and treat the skin’s various requirements in a targeted manner from the surface into the lower layers:
• makes the skin appear finer • mattifies the skin immediately and makes it smoother• corrects and reduces wrinkles • provides a fresh and radiant complexion
• with phyto stem cells• with pistachio tree extract• with tripeptides• with astragalus root extract• with HAF (hyaluronic acid fragments)• with ginger extract
Lubexanti-age®specific skin treatment Specific skin treatment products
Tip: Optimal for combination skin. Great for men as well !
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NEW STUDY
Lubexanti-age®vitamin C depigmenting concentrate
• reduces pigment and age spots • ensures an even complexion • reduces wrinkles and hydrates intensively• acts as a strong antioxidant
• with high dosed vitamin C• with soy isoflavone and cress sprout extract• with vitamin E• with HAF (hyaluronic acid fragments)
Tip: Use as a cure for 1 to 2 months or longer.
Clinical application study • reduces wrinkle depth by 32 %1 • changes ITA° (skin lightening) by 22 %1
• improves skin roughness (skin smoothing) by 13 %1 • Very good tolerability*1 Dermatest, Dr. med. Werner Voss, Clinical application study under
dermatological control. March 2018, DE-48143 Münster, Germany
*www.5-sterne-garantie.de
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Before After 1 month
Lubexanti-age®eye intensive intensive firming
• tightens the eye lids• smoothes eye wrinkles• acts against pouches as well as dark circles
and shadows
• with ash tree- and algae extract• with biochromones, peptides and complex of dipeptides• with HAF (hyaluronic acid fragments)
Lubexanti-age® specific skin treatment Around the eyes
Reduction of wrinkle depth after 1 month with twice daily application
Measurements with Visioline®
(exemplary 1:1 il lustration)
Tip: Also for lip contour.
NEW
36 37
Lubexanti-age®eye pads anti-wrinkle & skin-stress control
combination of highly concentrated active ingredients
• plumps up and moisturizes• smoothes mimic wrinkles• acts as an antioxidant and
counteracts stress factors• for cell detoxification
• with HAF (hyaluronic acid fragments) and ectoine®
• with complex of dipeptides• with plankton extract
Remove the pads from the package and detach them from the separating sheet. Place them below your eyes and relax for 15 minutes.
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NEW STUDY
Lubexanti-age®hydration oil black orchid
• hydrates sustainably• reduces wrinkles and sensation of skin tension
• with black orchid extract• with Kahai oil, Brazil nut oil und flavonoids
Lubexanti-age® specific skin treatment For silky-soft skin
Tip: Put a few drops on one hand and rub the palms together to warm the oil slightly. Apply to the skin while it is still moist from cleaning. Avoid the eye area.
Clinical application study • improves skin moisture by 44 %1 • improves skin elasticity by 25 %1
• improves skin tightness by 9 %1 • Very good tolerability*1 Dermatest, Dr. med. Werner Voss, Clinical application study under
dermatological control. March 2018, DE-48143 Münster, Germany
* www.5-sterne-garantie.de
*
NEW
38 39
Mineral UV filters adhere very well, so skin needs to be cleansed with a mild dermatological skin wash emulsion.
UV A+B all-round skin protection Lubex anti-age® sun fluid face SPF 50
Lubexanti-age®sun fluid face SPF 50
• protects against UVA/UVB radiation• acts as an antioxidant• protects against wrinkling,
cell and DNA damage (anti-pollution)• is well tolerated• does not irritate the eyes
• with 100 % mineral UVA+B filters SPF 50 • with ectoine®
Tip: Especially for sunlight-exposed areas.
Ideal for combining with Lubex anti-age®day classic and Lubex anti-age® day rich.
4040
Lubex anti-age® dermatological cleansing and refreshing
Tip:Remove all traces of make-up and the day’s debris with gentle Lubex anti-age® cleansing milk. Then refresh the skin with Lubex anti-age®
tonic. You will feel relaxed!
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Lubexanti-age®cleansing milk clarifying & antioxidant
• cleanses, nurses and regenerates stressed skin• acts as an antioxidant• gently removes make-up
• with provitamins C+E• with coenzyme Q10
Lubexanti-age®tonic (without alcohol) refreshing & hydrating
• hydrates intensively• acts as an antioxidant and calms the skin• tightens and refreshes the skin
• with hyaluronates and HAF (hyaluronic acid fragments)• with bisabolol and with hexapeptides• with vitamin C glucosides
Tip: Lubex anti-age® tonic is also recommended for men – especially after shaving.
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1. Cleansing Remove all eye make-up and gently cleanse your skin with Lubex anti-age® cleansing milk. Page 41
2. Clearing and refreshingLubex anti-age® tonic hydrates, calms and re-freshes the skin after cleansing. Page 41
3. Intensive hydrationAfter cleansing and refreshing, your skin will be ideally prepared for Lubex anti-age® hydration oil. The oil provides intensive hydration and reduces skin tension. Page 38
4. Specific skin treatment Ideally, you now apply one of our four effective Lubex anti-age® special skin treatment products such as serum, hyaluron 4 types, intelligence or vitamin C. From page 32
Lubexanti-age® professional active skin treatment regimen in 7 steps
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5. Active eyes contour treatment The first signs of aging are often seen in the eye area because of its very delicate and sensitive skin. This area of skin therefore needs to be treated with Lubex anti-age® eye intensive. Or you relax for 15 minutes with the Lubex anti-age® eye pads placed below the eyes. From page 36
6. Active day treatmentYou can use Lubex anti-age® active day treatment products (light, classic or rich, depend-ing on your skin requirements) to supply your skin with preventative and protective ingredi-ents, the optimum hydration factors and the correct amount of lipids (fats) during the day. From page 14
7. Active night treatmentThe appropriate Lubex anti-age® active night treatment product (light, classic or rich, depending on your skin requirements) ensures that the skin regenerates overnight thanks to skin-specific lipids, the intense hydration factors and effective regeneration ingredients. From page 14
Lubex anti-age® products are available in Switzerland at your pharmacy, drugstore and online.
44
Clinical Lubex anti-age® studies
4 5
Start Start
2 months 2 months
Start Start
2 months 2 months
8000
9000
10000
11000
12000
13000
1400012574,5 −10%
Start 2 Monate
11269,4*
15000*p=0,0001
Increase in skin densityNumber of black pixels in Dermascan**
**The lower the number of black pixels, the higher the skin density
n=30
8000
9000
10000
11000
12000
13000
1400012539,7 –9%
Start 2 Monate
11469,5*
15000*p=0,009
Increase in skin densityNumber of black pixels in Dermascan**
**The lower the number of black pixels, the higher the skin density
Competitor product with retinaldehyde
and HAF
n=30
500
600
700
800
900
1000848,5 −10%
Start 2 months
763,7*
*p=0,0059
Increase in skin tighteningParameter F4**
**The lower the value F4, the tighter the skin
n=30
500
600
700
800
900
1000
832,2 –9%
Start 2 Monate
753,7*
*p=0,007
Increase in skin tighteningParameter F4**
**The lower the value F4, the tighter the skin
Competitor product with retinaldehyde
and HAF
n=30
25
30
35
40
45
50
55
36,28
+29%
Start 2 months
46,93**p<0,0001
Increase in skin moisture (face)
n=30
Competitor product with retinaldehyde
and HAF
Increase in skin moisture (face)
25
30
35
40
45
50
55
36,56
+15%
Start 2 months
42,06*
*p=0,0016 n=30
1 Béguin A. Evaluation of the in vivo comparative anti-aging efficacy of two skin care products. A two-month randomized double-blind study on 30 healthy female volunteers. Study no.. CTE122A (2012).
1 Béguin A. Evaluation of the in vivo comparative anti-aging efficacy of two skin care products. A two-month randomized double-blind study on 30 healthy female volunteers. Study no.. CTE122A (2012).
Lubex anti-age® night richExample: Test subject no. 16
Competitor product with retinaldehyde and HAF
Example: Test subject no. 16
Result:With Lubex anti-age® night rich, the network
(green lines) is re-established and improves thereby the skin structure considerably.
Result:With Lubex anti-age® night rich, the skin be-
comes up to 10% tighter.
Result:With Lubex anti-age® night rich, skin mois-
ture is very significantly increased by 29%.
Result:With Lubex anti-age® night rich, the skin dens-
ity increases very significantly.
Skin tightening¹(Cutometer SEM 575)
Skin moisture¹(Corneometer CM825)
Skin density¹(DermaScan C)
An increase in the number of coloured pixels shows an increase in skin density (epidermis and dermis).
Skin structure¹(Visioscan VC98)
Klinische Anti-Aging-Studie mit Lubex anti-age ®day und Lubex anti-age ®night
Monozentrische klinische Studie über 3 Monate bei Frauen im Alter zwischen 45 und 60 Jahren mit mittelstark lichtgealterter Haut im Gesicht und Décolleté.
Dermatologische Klinik, Hôpital Saint Jacques, Besançon (Prof. Dr. med. Philippe Humbert) 2008
Anwendung morgens: Lubex anti-age cleansing milk (zur Reinigung) Lubex anti-age day
Anwendung abends: Lubex anti-age cleansing milk (zur Reinigung) Lubex anti-age night
- Hautphysiologische Messungen mit Reviscometer, Corneometer, Echographie, Visioscan - Fotografische Dokumentation mit Beurteilung im Doppelblindverfahren durch Dermatologen
- Auto-Evaluation
1. HAUTPHYSIOLOGISCHE MESSUNGEN a) Anti-Aging-Global-Index (Reviscometer, Corneometer, Echographie, Visioscan)
Resultat: Nach 3 Monaten Behandlung mit Lubex anti-age day + Lubex anti-age night verbessert sich der Anti-Aging-Global-Index im Gesicht und Décolleté signifi-
kant (p < 0.001).
b) Hautstraffung (Reviscometer)
Resultat: Nach 3 Monaten Behandlung mit Lubex anti-age day + Lubex anti-age night ist die Haut im Gesicht (p 0.05) und im Décolleté (p 0.006) signifikant straffer
geworden.
Gesicht Décolleté
Gesicht Décolleté
Start nach 3 Monaten Start nach 3 Monaten
Start 6 W 12 W Start 6 W 12 W
n = 30
n = 30
4 5
Start Start
2 months 2 months
Start Start
2 months 2 months
8000
9000
10000
11000
12000
13000
1400012574,5 −10%
Start 2 Monate
11269,4*
15000*p=0,0001
Increase in skin densityNumber of black pixels in Dermascan**
**The lower the number of black pixels, the higher the skin density
n=30
8000
9000
10000
11000
12000
13000
1400012539,7 –9%
Start 2 Monate
11469,5*
15000*p=0,009
Increase in skin densityNumber of black pixels in Dermascan**
**The lower the number of black pixels, the higher the skin density
Competitor product with retinaldehyde
and HAF
n=30
500
600
700
800
900
1000848,5 −10%
Start 2 months
763,7*
*p=0,0059
Increase in skin tighteningParameter F4**
**The lower the value F4, the tighter the skin
n=30
500
600
700
800
900
1000
832,2 –9%
Start 2 Monate
753,7*
*p=0,007
Increase in skin tighteningParameter F4**
**The lower the value F4, the tighter the skin
Competitor product with retinaldehyde
and HAF
n=30
25
30
35
40
45
50
55
36,28
+29%
Start 2 months
46,93**p<0,0001
Increase in skin moisture (face)
n=30
Competitor product with retinaldehyde
and HAF
Increase in skin moisture (face)
25
30
35
40
45
50
55
36,56
+15%
Start 2 months
42,06*
*p=0,0016 n=30
1 Béguin A. Evaluation of the in vivo comparative anti-aging efficacy of two skin care products. A two-month randomized double-blind study on 30 healthy female volunteers. Study no.. CTE122A (2012).
1 Béguin A. Evaluation of the in vivo comparative anti-aging efficacy of two skin care products. A two-month randomized double-blind study on 30 healthy female volunteers. Study no.. CTE122A (2012).
Lubex anti-age® night richExample: Test subject no. 16
Competitor product with retinaldehyde and HAF
Example: Test subject no. 16
Result:With Lubex anti-age® night rich, the network
(green lines) is re-established and improves thereby the skin structure considerably.
Result:With Lubex anti-age® night rich, the skin be-
comes up to 10% tighter.
Result:With Lubex anti-age® night rich, skin mois-
ture is very significantly increased by 29%.
Result:With Lubex anti-age® night rich, the skin dens-
ity increases very significantly.
Skin tightening¹(Cutometer SEM 575)
Skin moisture¹(Corneometer CM825)
Skin density¹(DermaScan C)
An increase in the number of coloured pixels shows an increase in skin density (epidermis and dermis).
Skin structure¹(Visioscan VC98)
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Study: comparison ofLubex anti-age® nightrich
and a competitor product
In this randomized double-blind clinical study* of 30 subjects aged 40 to 65 years, after two months equivalent to much better anti-aging effects were obtained with Lubex anti-age® nightrich in comparison with the competitor’s product (retinaldehyde + HAF):
Example: test person no. 20
start (original photo)
2 months (original photo)
4746
* Béguin A. Evaluation of the in vivo comparative anti-aging ef f icacy of two skin care products.
A two-month randomized double-blind study on 30 healthy female volunteers (2012).
Results of the studies
• The elasticity of the skin has increased significantly with Lubex anti-age® nightrich – in contrast to the comparative product.
• Lubex anti-age® night rich smoothes the skin about 3 times more.
• The skin is tightened slightly more with Lubex anti-age® nightrich and the facial skin is about twice as much hydrated.
• Lubex anti-age® night rich leads to a slightly stronger increase in skin density.
• With regard to the reduction of wrinkles, both products had a highly significant effect.
• Both products were well or very well tolerated with a slight superiority of Lubex anti-age® nightrich.
Conclusion
«In this double-blind clinical trial Lubex anti-age® nightrich has proven to be an ex-cellently effective anti-aging product for mature and dry to very dry skin with a good to very good tolerability.»*
Clinical double-blind study *
Lubex anti-age® day classic and night classic
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Single-centre study** over three months with women between 45 and 60 years of age with moderately photoaged facial and neckline skin:
Skin physiological measurementsAnti-aging global index
After three months of treatment with Lubex anti-age® dayclassic and Lubex anti-age® nightclassic the anti-aging global index for the face and neckline improves significantly.
neckline12
Ant
i-agi
ng g
loba
l ind
ex
7
9
8
10
11
Start after 3 monthsStart after 3 months
face12
Ant
i-agi
ng g
loba
l ind
ex
7
9
8
10
11
4948
Clinical anti-aging study* *
Summary of the clinical study results
• Skin tighteningAfter three months of treatment with Lubex anti-age® dayclassic and Lubex anti-age® nightclassic facial and neckline skin improves significantly.
• HydrationEven if the skin in the face and the neckline had been well hydrated already at the start of the study (approximately 51 corneometer units), a significant increase of hydration in the face and the neckline was reported after three months.
• Photographic documentationAfter three months of treatment the extent of the wrinkle depth assessed by dermatol-ogists with an objectified double-blind method had been greatly reduced both nasola-bially (fold from the nose to the mouth) as well as in the area of the eyes.
• ToleranceBoth products were well or very well tolerated.
* * Prof. Dr méd. Philippe Humbert, Dermatology Clinic, Hôpital Saint-Jacques, Besançon (2008).
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Lubexanti-age®products with dermatologically approved ingredients
For more detailed information on our dermatologically approved active ingredients, visit our homepage: www.lubexantiage.ch/ueber-lubex-anti-age/lubex-anti-age/glossar
Ingredients Product
highly active fragments of the natural hyaluronic acid (HAF), hyaluro-nates, microalgae extract, hexapeptides, ectoine, provitamins C + E
Lubex anti-age® daylight
biochromones and coenzyme Q10, hyaluronates, ceramides, ectoine, provitamins C + E
Lubex anti-age® nightlight
highly effective peptides, complex of dipeptides, highly active fragments of the natural hyaluronic acid (HAF), hyaluronates
Lubex anti-age® dayclassic
highly effective peptides, complex of dipeptides, highly active frag-ments of the natural hyaluronic acid (HAF), hyaluronates, 100 % mineral filters SPF 10
Lubex anti-age® dayclassicUV10
niacinamide, highly effective peptides, ectoine, multi-active AntiOx complex HDBM, UV filters SPF 30
Lubex anti-age® dayclassicUV30
stable microencapsulated retinol, coenzyme Q10, ceramides, provitamins C + E
Lubex anti-age® nightclassic
highly effective peptides, highly active fragments of the natural hyaluronic acid (HAF), soy isoflavone liposomes, apple stem cells, multi-active AntiOx complex HDBM
Lubex anti-age® dayrich
highly effective peptides, highly active fragments of the natural hyaluronic acid (HAF), soy isoflavone liposomes, apple stem cells, multi-active AntiOx complex HDBM; UVA+B filters SPF 20
Lubex anti-age® dayrichUV20
high-dosed retinol, coenzyme Q10, multi-active AntiOx complex HDBM, highly active fragments of the natural hyaluronic acid (HAF), hyaluronates, ceramides, soy isoflavone liposomes
Lubex anti-age® nightrich
50 51
Ingredients Product
biochromones, penta- and hexapeptides, resveratrol, ectoine, vitamin C glucoside, vitamin E, highly active fragments of the natural hyaluronic acid (HAF)
Lubex anti-age® serumanti-wrinkle serum
4 different types of long and short-chain hyaluron agents, provitamin C, vitamin E, coenzyme Q10, tripeptides
Lubex anti-age® hyaluron4typesintensive booster
peptides, phyto stem cells, pistachio tree extract, astragalus root extract, highly active fragments of the natural hyaluronic acid (HAF), ginger extract
Lubex anti-age® intelligencerefining & correcting biostimulator
vitamin C glucoside, soy isoflavone, cress sprout extract, vitamin E, highly active fragments of the natural hyaluronic acid (HAF)
Lubex anti-age® vitaminCdepigmenting concentrate
kahai oil, brazil nut oil, black orchid extract (contains flavonoids) Lubex anti-age® hydrationoilblack orchid
biochromones, algae extract, complex of dipeptides, ash tree extract, peptides, highly active fragments of the natural hyaluronic acid (HAF)
Lubex anti-age® eyeintensiveintensive firming
dipeptide complex, short-chain hyaluron agents, ectoine, plankton extract, cornflower water
Lubex anti-age® eyepadsanti-wrinkle & skin-stress control
provitamins C + E, coenzyme Q10 Lubex anti-age® cleansingmilkclarifying & antioxidant
hyaluronates, HAF, bisabolol, vitamin C glucosides, hexapeptides, provitamin E
Lubex anti-age® tonicrefreshing & hydrating
100 % mineral filters UV A+B, ectoine Lubex anti-age® sunfluidfaceSPF 50
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additional dermatological Lubex line extension products (OTC)
52 53
Dermatological competence since 40 years
54
For skin and hair – additional dermatological Lubex line extension products (OTC)
Dermatological shampoo with three-
fold care treatment for sleek hair
Gentle protective wash emulsion for daily inti-
mate care
Dermatological shampoo for irritated and
dandruff-prone scalp
Ichthyo®
l shampooLubex®
NEW NEW
54 55
Dermatologisches Körperöl
Soon with
NEW DESIGN!
Dermatological peeling with 2-phase effect for
face and body
Non-irritant dermatological washing and treatment foam
for face, hands and body
Dermatological lotion with threefold effect for
face and body
Dermatological body oil
Laa/
E/1
8090
7
Permamed AG, Ringstrasse 29, CH-4106 Therwil
Phone +41 61 725 20 20 | Fax +41 61 725 20 40
www.permamed.ch | www.lubexantiage.ch
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