Our New Organelle Our New Organelle Design Design

NitrosolvoNitrosolvo

Nitrosolvo means “to dissolve Nitrosolvo means “to dissolve nitrogen”nitrogen”

Name has Latin originsName has Latin origins Organelle is located in red blood cells Organelle is located in red blood cells Red blood cells are located in the Red blood cells are located in the

bloodstreambloodstream

Decompression SicknessDecompression Sickness

Your lungs inhale a certain amount of Your lungs inhale a certain amount of nitrogen in the airnitrogen in the air

When you are under water the nitrogen in When you are under water the nitrogen in your lungs becomes more dense because your lungs becomes more dense because there is more pressurethere is more pressure

The body seeks equilibrium with your The body seeks equilibrium with your lungs by diffusing nitrogen into muscle lungs by diffusing nitrogen into muscle tissue and bonestissue and bones

When you ascend towards the surface of When you ascend towards the surface of the water the pressure of the nitrogen in the water the pressure of the nitrogen in your lungs decreases and the pressure of your lungs decreases and the pressure of nitrogen in your blood and tissues nitrogen in your blood and tissues decreasesdecreases

When you ascend too quickly nitrogen When you ascend too quickly nitrogen will rush out of your blood in bubble form, will rush out of your blood in bubble form, causing decompression sicknesscausing decompression sickness

Symptoms include: headache, fatigue, Symptoms include: headache, fatigue, rash, joint pain, paralysis, tingling, rash, joint pain, paralysis, tingling, unconsciousness, or deathunconsciousness, or death

Nitrosolvo’s StructureNitrosolvo’s Structure

Nitrosolvo’s FunctionsNitrosolvo’s Functions

Nitrosolvo engulfs nitrogen bubblesNitrosolvo engulfs nitrogen bubbles Enzymes eat nitrogen bubblesEnzymes eat nitrogen bubbles Enzymes then release gasEnzymes then release gas The gas dissolves into bloodstreamThe gas dissolves into bloodstream

Nitrosolvo’s Nitrosolvo’s InteractionsInteractions

cell membrane: the organelle is stationed cell membrane: the organelle is stationed in the cell membrane in the cell membrane

lysosomes: the waste from the outside of lysosomes: the waste from the outside of the bubble is transported to the lysosomethe bubble is transported to the lysosome

mitochondrion: the organelle gets its mitochondrion: the organelle gets its energy from the mitochondrion because it energy from the mitochondrion because it has to change shape to let in the nitrogen has to change shape to let in the nitrogen bubbles. bubbles.

Positive EffectsPositive Effects Helps those who experience pressure changesHelps those who experience pressure changes Decreases risk of death by decompression sickness or Decreases risk of death by decompression sickness or

“the bends”“the bends” Mainly effects divers, sperm whales, and those in Mainly effects divers, sperm whales, and those in

airplanes that lose cabin pressureairplanes that lose cabin pressure

Negative EffectsNegative Effects

Nitrosolvo may allow a smaller amountNitrosolvo may allow a smaller amount of nitric oxideof nitric oxide Nitric oxide helps muscles relax and Nitric oxide helps muscles relax and

increase blood flowincrease blood flow

Project InspirationProject Inspiration

In one episode of House MD in which a man In one episode of House MD in which a man gets “The Bends” from Scuba Diving, surfacing gets “The Bends” from Scuba Diving, surfacing too quickly, and then boarding a plane. too quickly, and then boarding a plane.

We wanted to learn about decompression We wanted to learn about decompression sickness because it is not well known and the sickness because it is not well known and the topic of pressure arose in classtopic of pressure arose in class

After discussing the episode in class we After discussing the episode in class we decided to create an organelle that would allow decided to create an organelle that would allow the body to naturally adapt to changes in the body to naturally adapt to changes in pressurepressure

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