1.Osteoporosis is estimated to affect 200 million women worldwide - approximately one-tenth of women aged 60, one-fifth of women aged 70, two-fifths of women aged 80 and two-thirds of women aged 90 (2007) WHO Technical Report, University of Sheffield, UK: 66 It is projected that more than about 50% of all osteoporotic hip fractures will occur in Asia by the year 2050 (Osteoporosis Int 7:407.(1998) Osteoporosis seems to be a significant problem due to major nutritional issues as well as limited and underutilized diagnostic facilities Epidemiology, costs and burden of osteoporosis in Asia 2009.

2. Osteoporosis means Porous bones causes bones to become weak and brittle so brittle that even mild stress like bending over ,lifting a vacuum cleaner or coughing can cause a fracture In most cases bones weak when low levels of calcium phosphorus and other minerals in bones and result as low bone density As a common result of osteoporosis is fracture of the spine, hip or wrist Although it is often thought of as women s disease. Osteoporosis also effect many men 3. Symptoms Back pain which can be severe if fracture collapsed vertebra Loss of height over time with an accompanying stooped posture Fracture of wrist,vertebera ,hip and other bones 4. Normal bone has the appearance of honey comb matrix (left).Under microscope osteoporotic bone (right) looks porous bone 5. Causes The strength of the bones depends on their size and density; bone density depends on the amount of calicum,phosphours and other minerals bones contain When the bones contain fewer minerals than normal, they're less strong and eventually lose their internal supporting structure 6. Risk Factors Fractures from the osteoporosis are about twice more in women then men. Risk in women at menopause at age 45 that accelerate bone loss. Risk in men is greater than age 75 year The older the higher risk of osteoprosis,bones become weaker as ages Osteoporosis runs in families. Parent or sibling with osteoporosis puts at greater risk, especially if having a family history of fracture Men or women who are exceptionally thin or have small body frame have grater risk because they may have less bone mass to draw from as they age The greater womens lifetime exposure to estrogen, the lower higher risk of osteoporosis 7. Women and men with anorexia ,nervosa and bulimia are at Higher risk of bone density in their lower backs and hips Long term use like prednisone, cortisons, prednisolone and dexamethasone damaging to bone Too much thyroid hormone can cause bone loss Postmenopausal women who have breast cancer are at increased risk of osteoporosis especially treated with chemotherapy or aromatase inhibitor such as anastrazole and letrozole which suppress estrogen 8. A life long lack of calcium plays major role in the development of osteoporosis Stomach surgery (gastrectomy) can affect the bodys ability to absorb calcium Caffeine may interfere calcium absorption and its diuretic effect may increase the bone loss People who experience serious depression have increased rates of bone loss For men alcoholism is the leading risk factor of osteoporosis. Excess consumption of alcohol reduces bone formation and interfere with the bodys ability to absorb calcium 9. National osteoporosis foundation guideline Counsel on the risk of osteoporosis and related fractures Performed BMD Test for all postmenopausal women with fractures Recommended BMD for: Postmenopausal women 65 years 10. Treatment and Diagnosis Osteopenia refers to the mild bone loss that isnt sever enough to be called osteoprosis,but that increase risk of osteoporosis The best screening test is dual energy absorptiometry(DEXA) measure the density of bones in the spine, hip and wrist and its used to accurately following changes in the bones over time Ultrasound Quantitate CT scanning 11. Estrogen and Bone Protection Estrogen is essential for healthy bone and that when the production of estrogen is reduced, as occurs normally in Postmenopausal women and pathogenically after exposure to the radiation or chemotherapeutic drugs , bones become brittle and break easily 12. Ossein Mineral Complex Benefits OHC had a greater anabolic effect on bone than calcium carbonate Clin Drug Investig. 2011 Dec 1;31(12):817-24 OHC is significantly more effective in preventing bone loss than CC. Menopause.2009 Sep-Oct;16(5):984-91 Continuous administration of OHC prevents bone loss in postmenopausal women, suggesting that this drug may be useful in the management of postmenopausal bone loss. J Reprod Med. 1999 Jul;44(7):601-5 13. MCHC not only cures but also prevents the occurrence of osteoporosis It also reduces pregnancy snags & helps in rermineralisation of bone during lactation & in the normal course of life. It stimulates fracture healing. For rapid growth of children. It contains proteins, which help in sterilization body temperature and also help in physical growth & tissue repair. Uses For MCHC