On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in...
-
Upload
jerome-caldwell -
Category
Documents
-
view
215 -
download
0
Transcript of On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in...
![Page 1: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/1.jpg)
On the CUSP: Stop CAUTI in ICU National Content Webinar
Today’s Topic:
Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools; Using Results from
the Safety Culture Surveys
Access slides of today’s webinar on the national project website:
http://www.onthecuspstophai.org/on-the-cuspstop-cauti/cohort-9-icu-initiative/
1
![Page 2: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/2.jpg)
Webinar Evaluation
Your feedback is important!Please take a moment to fill out an evaluation
of today’s webinar:
http://www.cvent.com/d/xrqmmq
![Page 3: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/3.jpg)
Today’s Presenters
Mohamad Fakih, MD, MPH
Medical Director, Infection Prevention and Control
St John Hospital and Medical Center
Professor of Medicine,
Wayne State University School of Medicine
Detroit, MI
Pat Posa, RN, BSN, MSA, FAAN
System Performance Improvement Leader
St. Joseph Mercy Hospital3
![Page 4: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/4.jpg)
Today’s Presenters
William Miles, MD, FACS, FCCM, FAPWCA
Director of Surgical Critical Care
Clinical Professor of Surgery
University of North Carolina, Chapel Hill-Charlotte Campus
Carolinas Medical Center
Surgical Trauma ICU
Misty Wheeler, RN, NE-BC, CCRN
Lacey Spangler, RN, BSN, RN, CCRN
Neurosurgical ICU
Julia Retelski, MSN, RN, CCRN, SCRN, CCNS4
![Page 5: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/5.jpg)
Improving the Culture of Culturing (aka, Culturing Stewardship)
Mohamad Fakih, MD, MPH
Medical Director, Infection Prevention and Control
St John Hospital and Medical Center
Professor of Medicine,
Wayne State University School of Medicine
Detroit, MI
5
![Page 6: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/6.jpg)
6
Polling #1
A 45 year old male who is an active intravenous drug user is admitted with fever of 103°F, confusion and respiratory distress. The patient is intubated and admitted to the intensive care unit; the CXR shows multiple pulmonary emboli and the blood cultures grow methicillin resistant Staphylococcus aureus. On day 3, he is still febrile with a temperature of 101.8°F. His blood cultures are still growing gram-positive cocci and the patient has a urinary catheter since intensive care unit admission.
1. Urine culture2. No urine culture3. N/A – HRET Staff
![Page 7: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/7.jpg)
7
Polling #2
A 73 year old patient with prostatic hypertrophy was admitted to the hospital with abdominal discomfort. On admission, he was afebrile with normal vital signs and blood white cell count. A bladder scan showed a significantly distended urinary bladder. A urinary catheter was placed and 1200 ml of urine was drained. His abdominal pain improved and he did not complain of any respiratory symptoms. The patient spiked a fever of 102°F the next day. His blood pressure was 100 systolic and heart rate 110.
1. Urine culture2. No urine culture3. N/A – HRET Staff
![Page 8: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/8.jpg)
8
Clinical Evaluation
The clinical evaluation of the patient is key to best care, and the optimal use
of tests
![Page 9: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/9.jpg)
Bacteriuria with Catheter Use(Garibaldi et al, Infect Control 1982; 3: 466-70)
Daily bacteriologic monitoring of 1140 cases: • Bacteriuria at insertion: 99/1,140 (8.7%)
catheterizations• 1,041 had no colonization at insertion, 433
removed within 24 hours• Of 608 catheterizations >24 hours, 76 (12.5%)
developed bacteriuria• Risk of bacteriuria was 3% per catheter-day
9
![Page 10: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/10.jpg)
10
Picture of Routes of Entry
Maki and Tambyah, Emerg Infect Dis 2001; 7: 1-6
![Page 11: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/11.jpg)
11
Catheter Associated Bacteriuria in ICU(Clec’h et al, Infect Control Hosp Epidemiol 2007; 28: 1367-73)
• 12 ICUs: weekly urine cultures or if symptoms in catheterized patients
• CAUTI defined as urine culture >103 CFU/ml• CAUTI (bacteriuria) rate= 12.9/ 1000 catheter-days• Median time to CAUTI 11 days (range 6-19 days)• Median ICU LOS longer for those with CAUTI (28
days) vs. those without (7 days)
![Page 12: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/12.jpg)
Common Inappropriate Triggers For Urine Culture In Patients With Urinary Catheters
• Urine color, consistency and smell• Pyuria
12
![Page 13: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/13.jpg)
Resident Physicians (N=106) and Nurses (N=159): Triggers For Cultures In Catheterized Patients
(Sibai et al, ID Week 2013, presentation 205 )
Trigger for Urine Culture
Resident Physicians (Answered Yes)
Nurses(Answered Yes)
Foul smelling urine 75 (70.8%) 146 (94.8%)Cloudy urine 84 (79.2%) 146 (94.8%)Sediments in urine 57 (53.8%) 129 (84.3%)Darker urine 39 (36.8%) 72 (47.7%)Chronic UC on admission
46 (43.4%) 115 (74.2%)
All of the above should NOT trigger a urine culture in catheterized patients!13
![Page 14: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/14.jpg)
Resident Physicians and Pyuria: Obtain A Urine Culture In Catheterized Patients
(Sibai et al, ID Week 2013, presentation 205 )
Trigger for Urine Culture Answered Yes
Urine WBC 25 cells 71 (67%)
Urine WBC 100 cells 94 (88.7%)
Urine WBC 500 cells 101 (95.3%)
Pyuria in an asymptomatic patient with an indwelling urinary catheter should not be a
trigger for culture or antimicrobials
14
![Page 15: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/15.jpg)
Pyuria Is Not Diagnostic Of CAUTI(Hooton, Clin Infect Dis 2010; 50:625–663)
• Pyuria does NOT help differentiate asymptomatic bacteriuria from CAUTI
• Pyuria + bacteria ≠ CAUTI
15
![Page 16: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/16.jpg)
16
Pyuria and Bacteriuria(Tambyah, Arch Intern Med. 2000;160:673-677)
• 761 patients with newly inserted catheters, 10.8% developed bacteriuria or candiduria
• Defined bacteriuria as >103 CFUs.• Women had more bacteriuria (21.2%) than
men (7.2%)
![Page 17: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/17.jpg)
17
Pyuria and Bacteriuria(Tambyah, Arch Intern Med. 2000;160:673-677)
Pyuria more common with bacteriuria related to gram negatives than gram positives or funguria
![Page 18: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/18.jpg)
18
Pyuria and Bacteriuria(Tambyah, Arch Intern Med. 2000;160:673-677)
Pyuria cannot predict bacteriuria
![Page 19: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/19.jpg)
Absence of Pyuria (Hooton, Clin Infect Dis 2010; 50:625–663)
• IDSA guidelines: “The absence of pyuria in a symptomatic patient suggests a diagnosis other than CA-UTI”
19
![Page 20: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/20.jpg)
20
Color or Odor(Hooton, Clin Infect Dis 2010; 50:625–663)
• IDSA guidelines:“In the catheterized patient, the presence or absence of odorous or cloudy urine alone should not be used to differentiate CA-ASB from CA-UTI or as an indication for urine culture or antimicrobial therapy.”
![Page 21: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/21.jpg)
21
Screening Urine Cultures!!
The practice: “screening culture on admission”, “standing orders” or “reflex orders” for urine cultures based on urinalysis results 1. May not help the hospital avoid non-
reimbursement2. May increase utilization of additional
resources (testing, antibiotics, consults)3. May adversely affect patients by exposing
them to inappropriate testing and treatments
![Page 22: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/22.jpg)
PRE-PRINTED ORDERSFOLEY CATHETER PROTOCOL
22
![Page 23: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/23.jpg)
23
How to Reduce Unnecessary Urine Cultures
1. Evaluate current processes for obtaining urine cultures (avoid automatic triggers or screening cultures with no appropriate indications)
2. Evaluate practice patterns (avoid PAN culturing)
3. Provide education on when it is appropriate to obtain urine cultures
![Page 24: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/24.jpg)
24
How to Reduce Unnecessary Urine Cultures
4. Have periodic audits on urine culture use in the intensive care units to look for trends
5. Promote appropriate urinary catheter use to reduce risk of bacteriuria/ funguria
![Page 25: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/25.jpg)
Discourage Urine Culture Use
25
![Page 26: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/26.jpg)
Appropriate Urine Culture Use
26
![Page 27: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/27.jpg)
Key Points Related to Obtaining Urine Cultures
http://www.onthecuspstophai.org/on-the-cuspstop-cauti/toolkits-and-resources/additional-resources/27
![Page 28: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/28.jpg)
28
Culturing Stewardship and Other Preventative Measures: Large Hospital ICUs
Jul-Sep13 Oct-Dec13 Jan-Mar14 Apr-Jun14 Jul-Sep14 Oct-Dec140
0.5
1
1.5
2
2.5
CAUTI SIR for 50 Adult ICU Beds
CAUTI SIR
Influenza epidemic (more fever, more cultures)
ICU team only responsible for urine culture ordering
![Page 29: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/29.jpg)
Antibiotic Stewardship in the ICU
William Miles, MD, FACS, FCCM, FAPWCA
Director of Surgical Critical Care
Clinical Professor of Surgery
University of North Carolina, Chapel Hill-Charlotte Campus
Carolinas Medical Center
![Page 30: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/30.jpg)
Disclosures
Nothing to disclose
30
![Page 31: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/31.jpg)
Antibiotic Stewardship in the ICU
Some Points to Consider• Resistance to antibiotics exists in nature before
medicine actually discovers or uses them• Antibiotics have societal impacts• Pressure from antibiotic mismanagement forces
significant resistance• 70% of antibiotics in America go to Food
production
31
![Page 32: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/32.jpg)
Antibiotic Stewardship in the ICU
Antimicrobial Treatment Considerations
• Must be timely: any delay in starting them increases mortality significantly
• Appropriate: must cover spectrum of pathogens• Pharmacokinetics: adequate dose and intervals• Narrowing and Discontinuation: based on clinical
data, ICU microbiology data, and clinical response
32
![Page 33: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/33.jpg)
Antibiotic Stewardship
33
![Page 34: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/34.jpg)
Antibiotic Stewardship in the ICU
Novel Antibiotic Development
• 1980’s: 16 new antibiotics released• 1990’s: 10 new antibiotics released• 2000’s: 5 new antibiotics released
• 2008-2012: ONLY 1 new antibiotic developed!
34
![Page 35: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/35.jpg)
Antibiotic Stewardship in the ICU
What is Antimicrobial Stewardship
• Systematic approach to optimize clinical outcomes while minimizing consequence of antibiotic use:– Toxicity– Selection of Resistance– Selection of virulent organisms– C. diff resistance
• Combine with infection control practices to limit emergence and transmission of resistance
• Reduces healthcare costs without impacting care• Patient safety!
Dellit T et al Clin Infect Dis 2007; 44:15935
![Page 36: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/36.jpg)
Antibiotic Stewardship
• IDSA• Joint Commission• CMS-California mandate• CDC• Physician Leadership Forum• ATS /ACCP/SCCM
![Page 37: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/37.jpg)
Antibiotic Stewardship in the ICU
Goals of Antibiotic Stewardship
Combat the Emergence
of resistance
Control CostsImprove Clinical
Outcomes
37
![Page 38: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/38.jpg)
Antibiotic Stewardship in the ICU
Stewardship StrategiesPatient Evaluation Education/Guidelines
Choice of Antimicrobial Formulary Restrictions
Prescription OrderingComputer assisted strategies
Dispensing AntimicrobialReview and Feedback-includes all
38
![Page 39: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/39.jpg)
Antibiotic Stewardship in the ICU
Economic Considerations for Antibiotic Stewardship
• Antibiotic use restriction and costs should not be the only focus
• Antibiotic costs are a small percentage of treatment costs
• Costs from hospital LOS, total Healthcare costs and Infection Prevention should be considered
• Patients’ Quality and return to a functional life
39
![Page 40: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/40.jpg)
Antibiotic Stewardship in the ICU
Prescribing Antibiotics
• Day 1: Empiric Antibiotics– Based on disease and ICU’s biogram
• Day 3: Narrowing/De-escalation– Based on culture results– Infection vs. leukocytosis– What is clinical picture– Base it on Antibiogram of unit
40
![Page 41: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/41.jpg)
Antibiotic Stewardship in the ICU
• Antimicrobial Stewardship Principles important
• Utilize Pharm D, Infection Preventionist
• Prevent MDROs
41
![Page 42: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/42.jpg)
Antibiotics in UTI
• Pyuria either in the setting of negative urine cultures or in patients with asymptomatic bacteriuria usually requires no treatment. If pyuria persists consider other causes (e.g. interstitial nephritis or cystitis, fastidious organisms).
• Follow-up urine cultures or U/A are only warranted for ongoing symptoms. They should NOT be acquired routinely to monitor response to therapy.
• The prevalence of asymptomatic bacteriuria is high: 1%-5% in premenopausal women, 3%-9% in postmenopausal women, 40%-50% in long-term care residents and 9%-27% in women with diabetes.
http://www.hopkinsmedicine.org/amp/guidelines/Antibiotic_guidelines.pdf-2015
42
![Page 43: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/43.jpg)
Duration UTI Treatment
• The duration of treatment has not been well studied for CA-UTI and optimal duration is not known.
• 7 days if prompt resolution of symptoms• 10–14 days if delayed response• 3 days if catheter removed in female patient </= 65 years
with lower tract infection.
http://www.hopkinsmedicine.org/amp/guidelines/Antibiotic_guidelines.pdf-2015
43
![Page 44: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/44.jpg)
Treatment Notes UTI
• Remove the catheter whenever possible• Replace catheters that have been in >/= 2 weeks if still indicated
• Prophylactic antibiotics at the time of catheter removal or replacement are NOT recommended due to low incidence of complications and concern for development of resistance.
• Catheter irrigation should not be used routinely
http://www.hopkinsmedicine.org/amp/guidelines/Antibiotic_guidelines.pdf-2015
44
![Page 45: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/45.jpg)
Antibiotic Stewardship
Must coincide with Infection Control/Prevention• Prevention
– Optimal management of urinary catheters
• Control– Hand hygiene– Contact precautions– Active surveillance– Education– Environmental Cleaning Standards– Improved Communication between Facilities
www.cdc.gov45
![Page 46: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/46.jpg)
As The Wheels Turn
Antibiotic Stewardship
Micro Lab
Providers
Pharmacy
QI/QA
PATIENTS
Infection Control
46
![Page 47: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/47.jpg)
Multi-Drug Resistant Organisms
• CRE• MRSA• C Diff Colitis• All possible in ICU management and prolonged
urinary catheter and long term antibiotic use• Antibiotic stewardship and Urinary Catheter
removal protocols are essential tools for prevention of MDROs
47
![Page 48: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/48.jpg)
Antibiotic Stewardship
48
![Page 49: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/49.jpg)
Practical Implementation of Antibiotic Stewardship
2 ICUs Work In Implementing Antibiotic Stewardship And Appropriate Urinary Culturing
49
![Page 50: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/50.jpg)
Practical Implementation of Proper Culturing2 ICUs Experience
Surgical Trauma ICUMisty Wheeler, RN, NE-BC, CCRNLacey Spangler, RN, BSN, RN, CCRN
Neurosurgical ICUJulia Retelski, MSN, RN, CCRN, SCRN, CCNS
50
![Page 51: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/51.jpg)
51
Carolinas Medical CenterSurgical Trauma ICU
• Carolinas Medical Center is part of Carolinas HealthCare System in Charlotte, NC
• 874 licensed beds, quaternary referral hospital• Level 1 Trauma Center, Largest teaching hospital
in NC
Surgical-Trauma ICUNeurosurgical ICU
• 29 bed multispecialty trauma and surgical unit including transplant and immunotherapy patients
• 29 bed multispecialty Neurology and Neurosurgical unit
![Page 52: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/52.jpg)
52
Surgical-Trauma ICU CAUTI Reduction 2014-2015
Jan Feb Mar Apr May Jun July Aug Sept Oct Nov Dec Jan Feb Mar0
1
2
3
4
5
6
7
8
9
# of
CAU
TIs
Daily UCP/Nec audits and IUC care focus
Urine Culture Initia-tive
![Page 53: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/53.jpg)
53
NSICU CAUTI Reduction 2014-2015
![Page 54: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/54.jpg)
54
ICU Urine Culture Initiatives
• Oct. 2014 – Do not PAN Culture, culture based on patient clinical picture
• Nov. 2014– Correct Order Entry for Source by Provider and support for nursing
to change order if necessary – Education for correct urine collection
• Preservative tube, DO NOT use specimen cup
– Send Urinalysis prior to sending culture– Lab and nursing policy rewritten
• Feb. 2015– Lab to reject cultures not sent in correct tube
• March 2015– Lab to complete Reflex Testing on Urine Specimen
![Page 55: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/55.jpg)
Antibiotic Stewardship
Conclusions• Providers need better tools on how to initiate and
terminate antibiotics• Stewardship teams are just 1 step to regulate antibiotic
prescribing• Start based on national standards and Institutional
Antibiograms• De-escalate/narrow agents ASAP• Stop Antimicrobials based on clinical picture and do NOT
use Football Scores to decide length of treatment
55
![Page 56: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/56.jpg)
Antibiotic Stewardship and Proper Culturing
• They go hand in hand• Synergy with Teamwork• With team effort and following CUSP CAUTI
Policies and Guidelines can be achieved
56
![Page 57: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/57.jpg)
Safety Culture:Interpreting the Results
Pat Posa, RN, BSN, MSA, FAAN
System Performance Improvement Leader
St. Joseph Mercy Hospital
57
![Page 58: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/58.jpg)
58
What is a Culture?
Represents a set of shared attitudes, values, goals, practices and behaviors that makes
one until distinct from the next.
Unspoken, implicit, taken for grantedLargely invisible
Measure culture at the unit level
![Page 59: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/59.jpg)
Institute of Medicine
“ The biggest challenge to moving toward a safer health system is changing the culture from one of blaming individuals for errors to one in which errors are treated not as personal failures, but as opportunities to improve the system and prevent harm”
59
![Page 60: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/60.jpg)
A Positive Culture of Safety
…..recognizes the inevitability of error and proactively seeks to identify latent threats
Nieva, V F Qual Saf Health Care 2003;12(suppl)60
![Page 61: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/61.jpg)
Chaos, Culture, and Predictability
• Improve predictability = less chaos = better safety– Standardized interactions, checklists, familiarity
• Reduce predictability = more chaos = worse safety– New Manager, New Location, New Technology
61
![Page 62: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/62.jpg)
Why Measure Unit Culture?
• Determine how bedside staff are feeling related to communication and recognizing defects– Diagnose and assess the current status of patient safety culture.– Identify strengths and areas for patient safety culture improvement.– Examine trends in patient safety culture change over time.– Measure/evaluate the cultural impact of patient safety initiatives and
interventions.
• CUSP is the intervention that will help you improve culture results
62
![Page 63: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/63.jpg)
Survey Action Planning
Assessment data is likely to point to many different area of culture that can be improved
There will be many different ideas regarding potential actions
Incremental changes can be implemented and tested on a small scale, changing one process or practice at a time
Remember—in patient safety this is no one “silver bullet”
63
![Page 64: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/64.jpg)
64
Safety Culture Drill Down
• If low on teamwork – what pulled the score down?– Difficulty Speaking Up– Breakdowns in Interdisciplinary Care Coordination– Difficulty Resolving Conflicts– Difficulty Asking Questions
• If low on safety norms – what pulled the score down?– Lack of trust– Lack of feedback– Lack of engagement
![Page 65: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/65.jpg)
Changing the Culture Related to CAUTI
• Belief that any harm is not acceptable: – If this is present it will show up in categories of ‘non punitive
response to error’ and ‘feedback and communication about error’• Mindfully choose interventions:
– Don’t do things because “it is always how we have done it here” IE: pan culturing for any fever; indwelling urinary catheter in place because they are in the ICU
– Interdisciplinary discussion of risk vs benefit of starting antibiotics --- not just a routine, but thoughtful decisions
– This requires good interdisciplinary communication between team where each member of the healthcare team input is heard and valued
65
![Page 66: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/66.jpg)
Teamwork Climate is the Consensus of Frontline Caregiver Assessments Related to Collaboration
Example Teamwork Climate Scale Items: • In this clinical area, it is difficult to speak up if
I perceive a problem with patient care• Disagreements in this clinical area are
resolved appropriately (i.e. not who is right, but what is best for the patient)
• The physicians and nurses here work together as a well-coordinated team
66
![Page 67: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/67.jpg)
Safety Culture Debriefing
• Review results with staff• One strategy is to focus on:
– 5 areas with the most positive results– 5 areas with the most opportunities
67
![Page 68: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/68.jpg)
Summarize 5 MOST Positive
Supervisor/manager expectations/actions promoting safetyConsiders staff suggestions for improving pt safety-76%*My supervisor overlooks pt safety problems that happen
over and over—76% disagree Organizational Learning—Continuous Improvement
We are actively doing things to improve patient safety-80% Teamwork
People support one another in this unit-86%When a lot of work needs to be done quickly, we work together as a team-85% In this unit, people treat each other with respect-78%
68
![Page 69: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/69.jpg)
Summarize 5 LEAST Positive
Communication Openness Staff feel free to question the decisions or actions of those with more
authority-39% Feedback and Communication about Error
We are given feedback about changes put into place based on event reports—46%
Nonpunitive Response to Error *Staff feel like their mistakes are held against them—46% disagree *When an event is reported, it feels like the person is being written
up, not the problem—43% disagree *Staff worry that mistakes they make are kept in their personnel file-
33% disagree
69
![Page 70: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/70.jpg)
Summarize 5 least Positive
Hospital Handoffs and transitions*Things “fall between the cracks” when transferring
patients from one unit to another-33% disagree*Problems often occur in the exchange of information
across hospital units-38% disagree Teamwork Across Hospital Units
*Hospital units do not coordinate well with each other-39% disagree
70
![Page 71: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/71.jpg)
Evidence Based Local Solutions: Teamwork “If-Then”
If staffing levels inadequate/info lost at shift change: Then Morning/Shift Briefings
If interdisciplinary patient management issues: Then Daily Goals
If conflicts unresolved/role clarity lacking: Then Shadowing Exercise
If difficulty speaking up: Then standardizing with SBAR or Critical Language
71
![Page 72: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/72.jpg)
Evidence Based Local Solutions:Safety “If-Then”
If staff lack consensus about quality and safety issues? Then educate on the science of safety
If staff feel unengaged in safety and quality?Then build grassroots with Learning from Defects
If staff feel unengaged, unsafe, & unresourced for quality?
Then build infrastructure & capacity with Psychological Safety and Executive Partnerships
72
![Page 73: On the CUSP: Stop CAUTI in ICU National Content Webinar Today’s Topic: Urine Culture Practices in the ICU; Antibiotic Stewardship; Practical ICU Tools;](https://reader036.fdocuments.us/reader036/viewer/2022070415/56649d825503460f94a682b8/html5/thumbnails/73.jpg)
Questions?
Your feedback is important!Please take a moment to fill out an evaluation
of today’s webinar:
http://www.cvent.com/d/xrqmmq