Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ......
Transcript of Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ......
![Page 1: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/1.jpg)
Ohio Third Frontier Joint Meeting
December 7, 2017
![Page 2: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/2.jpg)
VFA: Ohio Fellows Program
![Page 3: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/3.jpg)
Ohio Fellows Program
Amy NelsonCEO, Venture for America
Elizabeth BrakeDirector of Ohio, Venture for America
![Page 4: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/4.jpg)
Opioid Programs Update
![Page 5: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/5.jpg)
![Page 6: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/6.jpg)
Idea Phase• 260+ submissions from 24 states, 39 Ohio counties• 50/50 professionals / citizen scientists• Submissions close Dec. 15; Winners announced Jan. 30
Challenge Phase• Launches in February; 3–4 challenge topics• Expert Advisory Panel• ~$2.5MM in prizes
Extensive Ohio and national coverage• Associated Press, Trade Pubs, Radio & TV• Tech2025
![Page 7: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/7.jpg)
Panel Discussion:Accelerating Scalability
![Page 8: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/8.jpg)
Panel Members
Moderator: Craig Chambers
Bill BaumelManaging Director, Ohio Innovation Fund
Bob BeechChairman, CEO & Co-founder, Eccrine Systems, Inc.
![Page 9: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/9.jpg)
Retreat OutcomesCY 2018 Program Plan
![Page 10: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/10.jpg)
Retreat Outcomes
Big Theme: Significantly increase number of portfolio companies more aggressively scaling; larger raises and revenue.
Connected sub-themes:• Mature the system; more exits • 4 or 5 Ohio-based $100mm VC Funds• Need a “scaling mindset” among startup community – more
advisors/executive talent that knows how to go from $1M to $25M sales
• “Not pipeline, but potential” – do more to support the folks that are already here
• “Speed to capital” – don’t leave entrepreneurs hanging on for six months or more
![Page 11: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/11.jpg)
Third Frontier Research andDevelopment Bond Funds
Current Balance
$230 Million
![Page 12: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/12.jpg)
Previously Committed for CY 2018
Entrepreneurial Services Program $34.4 mm Pre-seed/Seed Plus (projected disbursements) $15.0 mmOhio Fellows Program $0.8 mmDiversity & Inclusion Internship Program $0.5 mmOhio Opioid Technology Challenge $3.0 mm
Total $53.7 mm
![Page 13: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/13.jpg)
Continued and New Programming
Technology Validation & Startup Fund
Accelerator Catalyst Program
Coding Bootcamp Support
![Page 14: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/14.jpg)
Accelerator Catalyst Program
Why• Create access for new
participants• Increase visibility/flexibility• Recognize transience of
accelerator model• Breakout future OTF
accelerator support in one program
Focus• Industry/themed• Support for operations
(versus investments)• Limited OTF commitment
(time and $$)
![Page 15: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/15.jpg)
Accelerator Catalyst (continued)
Structure• 3-year grants, non-renewable
• Operating expenses up to $200,000 per cohort, 1-2 cohorts per year per program, matched 1:1
• Small, non-equity stipends
Eligibility• New applicants
• Current grantees who opt out of their ESP sub-grants* (for 2018 or 2019)
*Note: ESPs may propose to operate an accelerator directly, but as a separate grant/project
![Page 16: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/16.jpg)
Accelerator Catalyst (continued)
• Up to 3 new accelerators funded each year
• New or incremental scope only (no substitution of OTF funds for existing support)
• First cohort(s) second half of 2018
Maximum yearly outlay(assuming five-year program):• Year 1: $0.9M• Year 2: $2.7M• Year 3: $4.5M• Year 4: $3.6M• Year 5: $1.8M
Funding
![Page 17: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/17.jpg)
Coding Bootcamp Support
• Industry is mainly For-profit vs. Nonprofit Organizations
• Generally serve medium to large corporates
• OTF Role to Support:– Emphasis toward
Startup and Early Stage– Increasing diversity and
inclusion
• Further research:– Student demographic
make-up– Graduate placement efforts
(Startup vs. Big Corporates)– Long term expansion
strategies (cohort size vs. campus size)
![Page 18: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/18.jpg)
New Commitments for CY 2018
Technology Validation & Startup Fund $6.0 mmOhio Third Frontier Accelerator Program $1.0 mm Coding Camps $0.5 mmTotal $7.5 mm
Grand Total (including previously committed) $61.2 mm
![Page 19: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/19.jpg)
Ohio Third Frontier Commission Meeting
December 7, 2017
![Page 20: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/20.jpg)
TVSF
![Page 21: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/21.jpg)
Technology Validation & Start-up Fund Program
Lead Applicants/Phases• Phase 1: Ohio research institutions with sufficient internal deal
flow to support a multitude of Phase 1:Track A type projects. Awards from $200,000–$500,000 with 1:1 cash cost share.
• Phase 2: Ohio start-ups and young companies that are a prospective licensee of a technology from an Ohio institution. Up to $100,000 (or $150,000 if in MedTech) as initial capitalization with no cost share.
External Evaluator: Quantum Commerce
![Page 22: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/22.jpg)
Technology Validation & Start-up Fund Program
15th Cycle of the TVSF program. To date, including this cycle:
Current cycle• 21 proposals with 8 recommended for award• One new Phase 1 applied for funding, three returning for funding
Proposals Awards
Phase 1: Track A 232 93
Phase 1: Track B 13 13
Phase 2 197 72
![Page 23: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/23.jpg)
Phase 1 ProgressTo date, 77 Phase 1 complete.
$3,732,800 Awarded
59 Not YetLicensed
$3,594,000 Spent
12 of which have progressed to Phase 2 15
3
LicensedTo Startup
Licensed To Non-Startup
![Page 24: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/24.jpg)
Phase 2 ProgressTo date, 43 Phase 2 complete.
$4,932,198 Awarded$4,665,435 Spent
30 received equity investments totaling
$43.9M
7 Market Entry
24
11 Pre-MarketEntry
Trials/R&D
![Page 25: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/25.jpg)
Overall MetricsAcross the entire program: 148 Projects Reporting
121For Profit Jobs
Created
157Total Jobs Created
$4.6MProduct Sales
$43.9MFollow On
Equity
$14.9MFederal Grants
$69.04MTotal Leverage
![Page 26: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/26.jpg)
OTF TVSF – ROUND 15EVALUATOR REPORT
07 DEC 2017
![Page 27: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/27.jpg)
27
OVERVIEW – ROUND 15§ 8 of 21 proposals submitted this round are recommended for approval.
§ Total grant dollars recommended is $2,250,000.
**Note: Larger Recommendation Totals Reflective of Track 1B Participation.
Round Approval Rate $$ Recommended1 (APR 2012) 35% $950,0002 (AUG 2012) 52% $900,0003 (DEC 2012) 44% $610,0004 (JUN 2013) 30% $864,0005 (FEB 2014) 46% $1,462,0006 (JUN 2014) 39% $998,0007 (OCT 2014) 57% $1,100,0008 (FEB 2015) 37% $710,0009 (JUN 2015) 31% $550,000
10 (DEC 2015) 38% $925,00011 ( APR 2016) 46% $1,239,00012 (OCT 2016) 46% $3,537,269 **13 (MAR 2017) 38% $1,567,500 **14 (SEP 2017) 27% $498,83215 (DEC 2017) 38% $2,250,000 **
Overall 40% $18,161,601Average $1,210,773
![Page 28: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/28.jpg)
28
ROUND 15 RESULTS - APPLICATIONS BY INSTITUTION
Quantum Commerce, LLC
![Page 29: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/29.jpg)
29
TRENDS- ROUND 15
Quantum Commerce, LLC
![Page 30: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/30.jpg)
30
PHASE 1 PROPOSALS RECOMMENDED FOR FUNDINGRound 15
Quantum Commerce, LLC
Proposal # Lead Applicant Title State Funds Requested Total Budget Recommend
18-0266 CWRU Phase 1-Technology Validation Start-up Fund-Pool of Funds $500,000 $1,000,000 $500,000
18-2067 OU OU TVSF Phase 1B Program Fund $200,000 $400,000 $200,000
18-0268 CCF Cleveland Clinic Technology Validation and Start Up Fund II (TVSFII) $500,000 $1,000,000 $500,000
18-0269 OSU Accelerator Award $500,000 $1,000,000 $500,000
![Page 31: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/31.jpg)
31
TRENDS- ROUND 15
Quantum Commerce, LLC
![Page 32: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/32.jpg)
32
PHASE 2 PROPOSALS RECOMMENDED FOR FUNDINGRound 15
Quantum Commerce, LLC
PROPOSAL # Licensing Institution Lead Applicant PROJECT TITLE State Funds
Requested Total Project
Budget Recommended Capital Raised to Date
Time to Market
Additional Capital to Market
18-0276 TheClevelandClinicFoundation
EnhaleMedical,Inc.
HypoglossalNerveStimulationDevicefor
ObstructiveSleepApnea$150,000 $150,000 $150,000 $582,000 5 yr $9.0MM
18-0279 TheOhioStateUniversity
LENTECHSLLCLENTECHSSoftContacts
forPresbyopia$150,000 $150,000 $150,000 $25,000 1 yr $5.0MM
18-0283 TheOhioStateUniversity
SoteraMedical,Corp
EsophagealProtectionDevice
$150,000 $150,000 $150,000 $500,000 2.5 yr $1.5MM
18-0285 TheOhioStateUniversity
UbihereUbihere,Inc.
CommercializationProject
$100,000 $100,000 $100,000 $0 1 yr $200,000
![Page 33: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/33.jpg)
33
RESUBMISSION AND CARRY THROUGH
§Resubmission• Phase 2
• Seven of seventeen (41%) Phase 2 proposals are resubmissions.
• Four (57%) are Recommended for Funding.
§Carry Through• One of seventeen (6%) Phase 2 proposals were previous Phase 1 awardees.
• It is Recommended (100%) for Funding in this round.
Round 15
Quantum Commerce, LLC
![Page 34: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/34.jpg)
34
TRENDS –PHASE 1 PROGRAMS (AL L ROUNDS TO DATE)
Rounds 12 – 15 Results
10 Cumulative Programs Quantum Commerce, LLC
012345678
OCT2016
MAR 2017
SEP 2017
DEC 2017
Phase 1 - Track B Programs
Original Re-apply
![Page 35: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/35.jpg)
35
TRENDS -COMPARATIVE RESULTS (AL L ROUNDS TO DATE)
Rounds 1 – 15 Results
Phase 2 Applications
37% Cumulative Approval
Quantum Commerce, LLC
0
5
10
15
20
25
33% 63% 33%
38% 50%
33% 60% 57%
29% 40%
33% 27% 33% 27% 24%
![Page 36: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/36.jpg)
36
CUMULATIVE RESULTS – PHASE 2 (AL L ROUNDS TO DATE)
Quantum Commerce, LLC
![Page 37: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/37.jpg)
Ohio Opioid Abuse, Prevention and Treatment Technology Initiative
![Page 38: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/38.jpg)
BackgroundPurpose• Accelerate development and commercialization of promising new products (or
adaptations or modifications) in medical devices, diagnostics, pharmaceuticals, andhealth technology to address issues associated with the drug crisis driven by use,misuse, abuse and addictive potential of opioids. Projects must provide near-termtangible solutions associated with addiction prevention, treatment and overdoseintervention.
Project Focus• Projects advancing technologies that have already achieved technical proof of concept
and for which there is evidence of interest by a potential end-user
• Products that are already in the market where the objective of the project is to adapt ormodify those products to enable reduction of abuse, addictive potential and morbidityand mortality associated with opioid use.
External Evaluator• Quantum Commerce
![Page 39: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/39.jpg)
OHIO OPIOID ABUSE, PREVENTION AND TREATMENT
TECHNOLOGY INITIATIVEEVALUATOR REPORT
07 DEC 2017
![Page 40: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/40.jpg)
40
OVERVIEW
§ 29 organizations submitted proposals
§ Two removed from consideration during ‘quick down-select’ process
§ 27 proposals were all given an in-depth review
• Each fully assessed by 7 evaluators
§ 16 advanced to the interview stage
• Each further assessed by 5 evaluators
§ 7 proposals are recommended for funding
• Each vetted by a total of 9 team members for a minimum of 192 data points per proposal
• Funding recommendation totals ~ $10MM
![Page 41: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/41.jpg)
41
EVALUATION TEAM
Quantum Commerce, LLC
§ Gilbert Block (MD, PhD) - Pharmaceuticals/ Medical Technology
§ Robert Landfried (DO) - Medical Technology/ Diagnostics
§ Phil Drew (PhD) - Medical Device/ Diagnostics/ Health Technology
§ Amanda L Workman (PharmD) - Pharmaceuticals
§ End User* (Prior ER/ICU Nurse) - Opioid addiction and recovery perspective
§ Ellen Schoenfeld (3rdYear Med Student) - Research and Proof Editor
§ Camille Rechel (Chemist) - Business Commercial Review
§ Robert Worden (MBA) - Business Commercial Review/ Pharmaceuticals
§ Greg Workman (MBA, Chemist) - Business Commercial Review/ Pharmaceuticals
§ *Name of the end user reviewer is being withheld for privacy considerations
![Page 42: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/42.jpg)
42
§ Down-Select Phase:
• 3 Reviewers (business/ commercial)
• Consists of 14 largely administrative criteria from the Opioid RFP requirements
§ In-Depth Review Phase
• 7 reviewers (3 business and 4 technical experts).
• Consists of 20 criteria in the areas of:
• Program fit
• Crisis impact
• Scientific soundness
• Technological maturity
• Implementation feasibility
• Team and organizational business acumen
• Financial robustness.
METHODOLOGY
Impact Solution Importance
Solution Uniqueness Market Pull Time to
MarketTech
MaturityScientific
Soundness IP
Impact Technical Readiness
Existing Investment Team Project
ResourcesPath to Market
Commercial Capabilities
Market Barriers
Financial Stability
Commercial Readiness
![Page 43: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/43.jpg)
43
§ Interview Phase
• 5 Reviewers (3 business and Interventional Pain Clinician in person, plus End User indirect)
• Interviewee proposal(s) further appraised by an individual with the ‘End User’ perspective
• 10 specific criteria related to
• Real-world suitability combating the opioid crisis
• Integration/ implementation feasibility
§ Recommendations
• Concurrence with RFP criteria and intent
• Prioritized for Impact and Time to Market
METHODOLOGY – CONT.
![Page 44: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/44.jpg)
44
RYG SCORE CONTEXT
§ The RYG is divided into three main categories:
• Crisis Impact
• Technical Readiness
• Commercial Readiness
§ Further subdivided into 15 more granular segments.
§ Red indicates a high-level concern versus RFP criteria, yellow designates moderate concern, and green affirms criteria meet expectations of the Program.
§ Major concerns (Red) within a single sub-segment does not necessarily indicate a full failure
• Dependent upon the extent of the concerns generated during the review process
§ Full category finalized as red - proposal will not be recommended for funding
• Based upon the significance of concern in one segment, or
• Resultant of the category segments in summation
![Page 45: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/45.jpg)
45
RESULTS
Quantum Commerce, LLC
![Page 46: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/46.jpg)
46
PROPOSALS RECOMMENDED FOR FUNDING
Quantum Commerce, LLC
Proposal/LOI # Company Name Project Title Focus AreaRecommend Funds $MM
TECG201180006 Elysium Therapeutics, Inc. Novel Opioid Analgesics That Prevent Oral Abuse and Lethal Oral Overdoses
Pharmaceuticals $2.99
TECG201180018 Innovative Medical Equipment, LLC
ThermaZone Thermal Therapy for the Reduction of Opioid Usage
Medical Device $0.18
TECG201180020 Cordata Healthcare Innovations
Technology Enabled Overdose Intervention, Treatment and Prevention
Health Technologies
$1.50
TECG201180035 DeUmbra, Inc Predictive Analytics for the Early Identification of Opioid Addiction, Abuse and Overdose
Health Technologies
$0.86
TECG201180005 Sober First LLC The Ascent Solution Health Technologies
$0.46
TECG201180013 Sollis Therapeutics A long-acting, non-opioid, targeted delivery analgesic for severe sciatica pain.
Pharmaceuticals $2.00
TECG201180022 The University of Akron Post Operative Pain Management using Therapeutic Meshes
Medical Device/ Pharmaceuticals
$2.00
![Page 47: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/47.jpg)
A D D I T I O N A L R E F E R E N C E S B E L O W
![Page 48: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/48.jpg)
• Amanda L Workman (PharmD) Pharmaceuticals
• Doctorate of Pharmacy from the University of Kentucky
• Commercial Pharmacist for more than 15 years
• Board Licensed in Ohio and Kentucky
• Extensive experience dispensing opioids and other controlled substances to pain management patients in rural, urban, and suburban environments
• Practical customer interfacing and abuse challenges insight
Quantum Commerce, LLC
TEAM MEMBER CREDENTIALS
• Robert Landfried (DO) Medical Technology/ Diagnostics
• DO from the University of New England College of Osteopathic Medicine
• Board certified in anesthesiology and pain management
• Primary focus in interventional pain management
• Experience in implant technology, opioid management and behavioral cognitive approaches
• Medical Director of a Pain Management Medical Center
• Gilbert Block (MD, PhD) Pharmaceuticals/ Medical Technology
• MD from Case Western Reserve University
• PhD in Reproductive Biology/Neuroendocrinology CWRU
• Lengthy career in neurology / neuropharmacology
• Academic, foundation and NIH review committees
• Venture capital companies
• Fentanyl and non-abusable opiates development programs
• Phil Drew (PhD) Medical Device/ Diagnostics/ Technology
• Ph.D. in Electrical Engineering from Harvard University
• M.S. in Applied Mathematics from Harvard University
• B.S. in Mechanical Engineering from Carnegie-Mellon University
• Extensive experience in Medical Imaging, Health Care, and Hospital Operations
• Strategic Analysis, Facility Planning, and Organizational Feasibility Studies
![Page 49: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/49.jpg)
Quantum Commerce, LLC
TEAM MEMBER CREDENTIALS – CONT.
• Ellen Schoenfeld Research and Proof Editor
• Third-year medical student at Marian University College of Osteopathic Medicine
• B.S. Health Sciences from the University of Cincinnati
• -- End User*End-User perspective of Opioid addiction and recovery
• Previous Emergency Room and ICU nurse
• United States Air Force - Air Traffic Control Division
• Addicted to opiates for six years, and overdosed once
• Recovering addict - seven years of sobriety
• Sponsor of more than 50 individuals seeking treatment and recovery
• *Name of the end user reviewer is being withheld for privacy considerations
![Page 50: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/50.jpg)
Quantum Commerce, LLC
TEAM MEMBER CREDENTIALS – CONT.
• Robert Worden (MBA) Business Commercial Review/ Pharmaceuticals
• MBA from the Darden School at the University of Virginia
• Certified Six Sigma Black Belt
• Over 20 years experience in life sciences, food and consumer products, specialty chemicals, apparel, and community outreach.
• Front line of the opioid crisis, connecting clients battling addiction with treatment, counseling, housing options and medical care
• Experienced reviewer/ leader for TVSF and TCC programs
• Camille Rechel (Chemist) Business Commercial Review
• BS Chemistry from the University of Cincinnati (ACS)
• Over 25 years of Business Management experience in chemical, food, medical device, pharmaceutical, recruiting, and industrial electronics industries
• Patents for polymeric coatings
• Core competencies in customer service, product commercialization, and business development
• Experienced reviewer/ leader for TVSF and TCC programs
• Greg Workman (MBA, Chemist) Business Commercial Review/ Pharmaceuticals
• MBA from American Intercontinental University
• BS Chemistry from Otterbein University (ACS)
• Certified Six Sigma Master Black Belt and Certified Quality Manager
• Over 25 years experience in food, pharmaceuticals, and chemical manufacturing; electronics; logistics, and construction services
• Design implementation of Management Systems and Manufacturing Processes from Biotech startups to Fortune 500 multinationals.
• Experienced reviewer/ leader for TVSF and TCC programs
![Page 51: Ohio Third Frontier Joint Meeting December 7, 2017 more aggressively scaling; larger raises and ... Ohio Opioid Technology Challenge $3.0 mm ... Ohio Third Frontier Accelerator Program](https://reader036.fdocuments.us/reader036/viewer/2022081517/5acde94e7f8b9ad13e8ea50a/html5/thumbnails/51.jpg)