Ohio Center of Excellence on Knowledge-Enabled Computing (Kno.e.sis)

Ohio Center of Excellence on

Knowledge-Enabled Computing (Kno.e.sis)

Ohio Center of Excellence on Knowledge-Enabled Computing (Kno.e.sis)

scientia potentia est

Knowledge is Power Francis Bacon, 1597

…established and popularized deductive methodologies for scientific inquiry

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Agriculture Industrial Service Knowledge

Ohio Center of Excellence Knowledge-Enabled Computing (Kno.e.sis)

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… we live in a Knowledge Society

Our society has progressed from

Agriculture Manufacture Service KnowledgeLand, seeds, labor

Labor, machines, raw material

Skilled people

Creative people who innovate

… new era … where the principal component of value creation, productivity and economic growth is knowledge. Florida & Kenny 91

As the economies have transformed ….

Knowledge Economy

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Knowledge EconomyTh

ousa

nds

knowledge-intensive services are leading the all sector in job creation, R&D spending, average wages and growth.

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Structured text (Scientific

publications / white papers)

Experimental Results Clinical Trial Data

Public domain knowledge (PubMed)

Metadata Extraction/Semantic Annotations

Domain Models/

Knowledge

Meta data / Semantic Annotations

Biomedical Knowledge Discovery,Knowledge Management & Visualization

Massive amounts of data

Search and browsing

Patterns / Inference / Reasoning

2D-3D & Immersive Visualization, Human Computer Interfaces

Impacting bottom line

Knowledge discovery

Migraine

Stress

Patient

affects

isaMagnesium

Calcium Channel Blockers

inhibit

SEMANTICS, MEANING PROCESSING

Kno.e.sis’ leadership in semantic processing will contribute to basic theory about computation and cognitive systems, and address pressing practical problems associated with productive thinking in the face of an explosion of data.

Kno.e.sis intends to lead a march from information age to meaning age.

Kno.e.sis Vision

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• We have exciting vision built on cutting edge research and technology

• We incorporate synergy to carry out exceptional vision

• We are world class – and recognized as such• Our track record shows we can succeed• We target the growth aspect of economy and

regional/state needs

Why Kno.e.sis?

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Human Sciences & Health Care

Advanced Data Management

Defense/Aerospace R & D

Application to Regional Industry Cluster

daytaOhio – a WCI

• Visualization and Data Mgt Infrastructure

• Consulting and Technology Transfer

Kno.e.sis+Faculty Strengths• Cognitive Science & Human Factors• Data Analysis/Mining/Visualization• Info. & Knowledge Mgmt• Web 3.0 (Semantics, Services, Sensors)• Virtual Worlds, Social Computing• High Performance/Cloud Computing• Bioinformatics/Biomedicine, Healthcare

Academic Research and Infrastructure

Globally Competitive Careers and Economic Development

Dayton Region Companies

Woolpert SAIC

REI Tech, Aptima LexisNexis

WPAFB Directorates

Human Effectiveness Sensor

Knowledge Workers, Products, Services and Applications

Tech^Edge

Significant Infrastructure

NMR

Whole-Body Laser Range Scanner

VERITAS

stereoscopic 3D visualization

AVL

Exceptional Regional Collaboration

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• At least 6 active projects with AFRL/WPAFB• Human Effectiveness Directorate• Sensors Directorate

Exceptional National Collaboration

• Univ. of Georgia, Stanford, Purdue, OSU, Ohio U., Indiana U. UC-Irvine, Michigan State U., Army, W3C

• Microsoft, IBM, HP, Google

• U. Manchester, TU-Copenhagen, TU-Delft, DERI (Ireland), Max-Planck Institute, U. Melbourne, U Queensland, NICTA-Australia, CSIRO, DA-IICT (India)

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Exceptional International Collaboration

Knowledge & Next Generation of the WebWeb has become the core infrastructure for the knowledge economy

Web 1.0: Web of Documents and MediaWeb 2.0: Web of People

Web 3.0: Web of Meaning

Meena Nagarajan

Knowledge & Next Generation of the WebWeb has become the core infrastructure for the knowledge economy

Web 1.0: Web of Documents and MediaWeb 2.0: Web of People

Web 3.0: Web of Meaning

Meena Nagarajan

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Advanced Data Management

KNOWLEDGE EXTRACTION

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“Human Cognition” AND Psychology AND Neuroscience?

“Human Cognition” AND Psychology AND Neuroscience

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Harvesting Community Knowledge & Scientific Corpus

Human Performance &Cognition Ontology

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INSIGHTS &

KNOWLEDGE DISCOVERY

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“EGF and hypoxia induce CXCR4 in non-small cell lung cancer...” [PMID:15802268]

“PTEN protein could inhibit cell invasion even in the presence of ... epidermal growth factor receptor (EGFR)” [PMID: 15986432]

Record navigation trail: ●EGFR induces CXCR4

Data Exploration on the Web

Utilizes semantic information from domain models to guide user interaction

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Cuebee and Scooner

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Shared as open source, with demos online.

SEMANTIC SENSOR WEB

Ohio Center of Excellence Knowledge-Enabled Computing

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Environment

Situation Awareness

Sensor

Sensor Data

Observation

Perception

Utilizes semantic technologies to bridge the divide between the “real-world” and the Web

Physical World (“real-world”)Information Space (Web)

Semantic Sensor Web

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Semantic Sensor WebLinked Sensor Data provides semantic descriptions for:

• ~20,000 weather stations in the United States.

• 160 million observations (~2 billion statements).

• named locations that are nearby (in Geonames)

weather station

near

SEMANTIC SOCIAL WEB

Ohio Center of Excellence Knowledge-Enabled Computing (Kno.e.sis)

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Everyone Wants to talk

…and be heard!

Hundreds and thousands of tweets, facebook posts, blogs about a single event, multiple narratives, strong

opinions, breaking news..28

TWITRIS : Twitter+Tetris

• Our attempt to help you keep up with citizen observations on Twitter– WHAT are people saying, WHEN, from WHERE

• Puts citizen reports in context for you by overlaying it with news, wikipedia articles!

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Twitris Demo

Biomedical & Health SciencesFrom data to understanding

Mike Raymer


Mike Raymer

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Human Sciences & Health Care

Many biomedical collaborations: Nick Reo, Toxicology; Tim Cope, Neuroscience;Jerry Alter, Protein Science; Oleg Paliey, Microbiolgy and healthMany health care collaborations: Kate Cauley, Center for Healthy Communities; UC-Irvine – Emergency health, Sonia Michail, obesity & intestinal health; Bradley Jacobs, human health


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Perez-Iratxeta, C. et al. Brief Bioinform 2007 8:88-95; doi:10.1093/bib/bbl035

Computation & Life SciencePublication/Funding Trends


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• Toxicology• Neuroscience• Protein science• Pediatrics• Clinical

psychology

• Obesity• Krohn’s disease• Treating

Schizophrenia• Emergency Health

Cross-disciplinary workHow we do it

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• Determine whether exposure has occurred– Including low-dose exposure

• Predict downstream outcome– Organ/system toxicity vs. recovery

• Using easily deployable tests– Blood, urine, etc.

Cross-disciplinary workHow we do it - 2

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Nationwide HealthHealth Bank or

PHR Support Organization

Community #1

IntegratedDelivery System

Community Health Centers

Community #2

State and Local Gov

Labs

Pharmacies

CDC

VA

IHS

DoD

SSA

As part of Nationwide Health Information Network effort, Center for Healthy Communities (CHC) will use its HIExTM system, supported through Wright State HealthLink and medical providers to electronically transmit data from their certified EHRs to the Social Security Administration (SSA). This will improved quality of care through analysis of large data sets documenting treatments and outcomes. Knoesis will be in the forefront creating the systems intelligence to better understand this complex, integrated information both at the individual provider level and in the realm of population health. CHC received ~1M contact from SSA.


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Data Information

Understanding

Cognitive Science & applications to Human EffectivenessJohn Flach

Cognitive Science & applications to Human EffectivenessJohn Flach

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Defense/Aerospace R & D

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Brightest Idea Award:National Center for Technology Innovation

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VERITAS Robert Gilkey

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Cognitive Systems Engineering

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Cognitive Systems Engineering

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GRAPHICAL INTERFACESKevin Bennett

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Total Energy Path Display

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Putting Humans Into Control

Samuel Pierpont

Langley

Samuel Pierpont

Langley

Regional Impact

Collaboration by daytaOhio and the Dayton Development Coalition to Leverage Kno.e.sis

Terry Rapoch – President/CEO daytaOhio Jim Leftwich – CEO Dayton Development Coalition

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Regional Development Model

Advanced Data

Analysis

Knoesis

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Collaboration Objectives

• Complement the knoesis Center in two ways that are consistent with daytaOhio’s vision and regional role– Expanding the scope of R&D into knowledge services– Identifying opportunities to commercialize the knowledge

services developed by Kno.e.sis• Enhance the impact of Kno.e.sis on regional economic

development– Attracting more research funding and talent – Providing commercial channel for knoesis innovations– Supporting knowledge base start ups – Bringing new products and service to existing businesses

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Process

• Continue to develop initial opportunities with LexisNexis

• Catalog knoesis Intellectual Property available for commercialization

• Qualify additional partners in the region working with Dayton Development Coalition

• Expand role of knoesis in regional human centered innovation opportunities

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Partners

• Research and development– Evaluation of systems and process

using Virtual Reality– Integration of sensors into

immersive visualizations– Medical – post processing of

images into immersive environments

• Commercial direction– Integration, knowledge services IP– Data center energy

AFRL/HPW-RHCB/WSU

SAIC • Sensor web

Kettering/Siemens• Image knowledge extraction

LexisNexis• Ontology, semantics browsers

Ohio IT Alliance/Point Energy Solutions• Knowledge extraction53

Advisory BoardProf. Ramesh Jain

First Bren Professor in Bren School of Info & Comp Sc, UC-Irvine. Founder of four companies. Chairman of ACM SIG Multimedia, founding EIC of IEEE Multimedia. Fellow of ACM, IEEE, IAPR, AAAI, and SPIE.

Prof. Gerhard Weikum

Research Director, Max-Planck Institute for Informatics, Germany. Member of the German Academy of Science and Engineering, ACM Fellow, CIDR 2005 Timeless Idea Award, VLDB 10-Year Award 2002, ACM SIGMOD Conference 1998 Best Paper Award.

Prof. Ahmed Elmagarmid

Professor, Computer Science; Director, Cyber Center. Presidential Young Investigator award from the National Science Foundation. Earlier served as a chief scientist in the Office of Strategy and Technology at HP. IEEE Fellow.

Krishna Joshi

Founder, UES Inc. a Dayton company since 1973. It provides Support to DoD, EPA, DoE, NASA, NSF. Prominent entrepreneur and benefactor of the Miami Valley. Kno.e.sis and daytaOhio are housed in the Joshi Research Center named after Krishna and Vicky Joshi.

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Board of Advisor’s View

Prof. Ahmed ElmagarmidCyber Center – Discovery Park

Purdue University


• Over 2,000 citations per faculty, around 1,000 refereed publications – comparable to any excellent group; granted 74 PhDs, $50 million in cumulative funding

• Prof. Sheth among the most cited Computer Science authors in the world today (top 30 based on h-index)

• Prof. Bennett & Flach’s papers as one of most influential papers published in over 50 years in Journal of Human Factors; Prof. Raymer’s paper was cited in a US Supreme Court decision

• Kno.e.sis has attracted top-notch faculty• High quality funding: NIH, NSF, AFRL…..innovation grants:

Microsoft Research, Google, IBM Research, HP labs• Entrepreneurship experience – launched several companies

Faculty

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Jan-07

Jan-08

Jan-09

$25,000

$275,000

$525,000

$775,000

$1,025,000

$1,275,000

$1,525,000

$1,775,000

$2,025,000

$2,275,000

$2,525,000

$2,775,000

$3,025,000

$3,275,000

$3,525,000

$3,775,000

$4,025,000

$4,275,000

FederalIndustryStateTotal

Funding (7 faculty)

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Funding

Starting with current active funds of $8-10 million (supporting research of 15 faculty and 45+ funded grad students & postdocs) Kno.e.sis anticipates growing to $13 million in 5 years and $19.5 million in 10 years (25 faculty plus 75 researchers)

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World Class Students• Meena Nagarajan gave a keynote at an international

workshop– unheard of for a PhD student

• Satya, Cory, Karthik organized international workshops

• Six of the senior PhD students: 84 papers, 43 program committees, contributed to winning NIH and NSF grants.

• Lyubomir Zagorchev, a recent alumni invited to give a talk at Harvard.

• Students interned at & collaborated with the very best places: Microsoft Research, Yahoo! Research, IBM Research, HP Labs, NLM, …and filed for 6 patents in 2 years

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Opportunities and Challenges

Noteworthy• Possibly the largest or second largest academic research group in

the US in Semantic Web (key enabled of Web 3.0)• Internationally recognized faculty• Demonstrated ability to prepare world class students• Regional, National and International Collaborations and Leadership

(eg W3C)• Recognition of the opportunity from the University leadershipAdequate but will need to grow to support growth• Infrastructure (computing, space)• Institutional/State Support: administrative and business support

(e.g., grant writing), Faculty lines• Continued effort to attract best local, US and international students

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Metrics

How we propose to benchmark/evaluate the progress?• Recognition & Visibility (be #1, 2, or 3 in US)

• Funding (200% of averages in respective unit; over average of COE’s at tier 1 institutions)

• Student Achievements (15 to 20% above national &regional averages for salaries, placement in top 20% of high value jobs)

• Faculty Achievements (publications at 200% of respective units)

• Collaborations • Economic Impact

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Kno.e.sis - information age to meaning age

Thank You

Ohio Center of Excellence on Knowledge-Enabled Computing (Kno.e.sis)

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