Vol. 268, No. 28 The Journal of October 5, 1993

Biological Chemistry Copyright 0 1993 by the American Society for Biochemistry and Molecular Biology, Inc.

428 East Preston St., Baltimore, MD 21202 U.S.A.

CONTENTS*

MINIREVIEW 20741 Substituting isoserine for serine in the thrombin recep- tor activation peptide SFLLRN confers resistance to aminopeptidase "induced cleavage and inactivation. Barry S. Caller, Karen T. Springer, Lesley E . Scudder, Jeffery L. Kutok, Marc0 Ceruso, and Glenn D. Prestwich

20683 Outside and downstream of the homeobox. Gerald M . Edelman and Frederick S. Jones

COMMUNICATIONS 20744 Three-dimensional structure of rat acid phosphatase in

20687 A helix-loop-helix transcription factor-like gene is lo- complex with L(+)-tartrate. Ylva Lindquist, Gunter Schnei-

Joan M. Krakowsky. and Kathleen P. Anderson cated at the mi locus. Michael J . Hughes, Jerry B Lingrel, der, and Pirkko Vihko

20691 Molecular piracy of mammalian interleukin-8 receptor type B by herpesvirus saimiri. Sunil K. Ahuja and Philip M. Murphy

20747

20695 Potent inhibition of human tumor p21- farnesyltrans-

Meenakshi Nigam, Churl-Min Seong, Yimin Qian, Andrew D. ferase by A,A2-lacking p21-CAlAzXpeptidomimetics.

Hamilton, and Said M. Sebti 20756

20699 Preferential binding of histone H1 to four-way helical junction DNA. Patrick Varga- Weisz, Kensal van Holde, and Jordanka Zlatanoua

20762 20701 Stimulation of tyrosine phosphorylation and accumu-

lation of GTP-bound p21" upon antibody-mediated a261 integrin activation in T-lymphoblastic cells. Car-

John Wilkins, and Shoukat Dedhar olyn Kapron-Bras, Linda Fitz-Gibbon, Premala Jeeuaratnam,

20768 20705 Biosynthesis of heparinlheparan sulfate. Identification

of a 70-kDa protein catalyzing both the D-glucurono- syl- and the N-acetyl-D-glucosaminyltransferase reac- tions. Thomas L i d , Ulf Lindahl, and Kerstin Lidholt 20772

20709 The p27 catalytic subunit of the apolipoprotein B mRNA editing enzyme is a cytidine deaminase. Na- veenan Nauaratnam, John R. Morrison, Shoumo Bhatta- charya, Dzptr Patel, Toru Funahushi, Federico Giannoni, 20778 Ba-Bie Teng, Nicholas 0. Dauidson, and James Scott

ARTICLES Molecular cloning and functional expression of human acyl-coenzyme A:cholesterol acyltransferase cDNA in

Chang, Ho Young Huh, Kenneth M. Cadigan, and Ta Yuan mutant Chinese hamster ovary cells. Catherine C. Y .

Chang

Role of the interdomain linker peptide of Trichoderma reesei cellobiohydrolase I in its interaction with crys- talline cellulose. M a k e Srisodsuk, Tapani Reinikainen, Merja Penttilii, and Tuula T. Terri

Glutamine 170 to tyrosine substitution in yeast mito- chondrial F1 B-subunit increases catalytic site interac- tion with GDP and IDP and produces negative cooper- ativity of GTP and ITP hydrolysis. Jean-Michel Jault, Gilles Divita, William S. Allison, and Attilio Di Pietro

Two-dimensional, rotational-echo double-resonance NMR of cell culture metabolism. Lynda M. McDowell, Eric R. Cohen, and Jacob Schaefer

Related signals for endocytosis and basolateral sorting

Fuhrer, Birgit Leitinger, Martina Weiss, Katja Huggel, Gillian of the asialoglycoprotein receptor. Iris Geffen, Christian

Griffith, and Martin Spiess

Asp304 of Escherchia coli acid phosphatase is involved in leaving group protonation. Kirill Ostanin and Robert L. Van Et ten

20713 Arachidonic acid release from aortic smooth muscle cells induced by [Ar$]vasopressin is largely mediated by calcium-independent phospholipase Az. John J . Leh- man, Kathryn A. Brown, Sasanka Ramanadham, John Turk, and Richard W . Gross ard E. McCarty

20785 Influence of nucleotide binding site occupancy on the thermal stability of the F1 portion of the chloroplast ATP synthase. Zhen- Yuan Wang, Ernest0 Freire, and Rich-

20717 Lysophosphatidic acid stimulates mitogen-activated 20791 Plasminogen activation stimulates an increase in intra- protein kinase activation via a G- rotein-coupled path- cellular calcium in human synovial fibroblasts. Mario way requiring p21'" and ~74 '~ ' . Louise R. Howe and Gonzalez-Gronow, Govind Gawdi, and Salvatore V. Pizzo Christopher J . Marshall 20796 Characterization of the third member of the MCAT

20721 Interaction between a complex of RNA polymerase 111 family of cationic amino acid transporters. Identifica- subunits and the 70-kDa component of transcription tion of a domain that determines the transport proper- factor IIIB. Michel Werner, Nathalie Chaussiuert, Ian M . ties of the MCAT proteins. Ellen Ildicho Class, C. Richard Willis, and Andre Sentenac Lyons, Carol Kelly, and James M. Cunnzngham

20725 Lipopolysaccharide induces activation of CD 4-asso- ciated protein tyrosine kinase ~S3/56 '~ ' . Irena defanova, Marta L. Corcoran, Eva M. Horak, Larry M. Wahl, Joseph B. Bolen, and Ivan D. Horak

20801 Cloning and characterization of the gene encoding the human platelet glycoprotein V. A member of the leu- cine-rich glycoprotein family cleaved during thrombin- induced platelet activation. Franpis Lanza, Martine Mo- rales, Corinne de La Salk, Jean-Pierre Cazenaue, Kenneth J.

20729 Follicle-stimulating hormone regulation of A-kinase Clemetson, Takeshi Shimomura, and David R. Phillips anchoring proteins in granulosa cells. Daniel W. Carr, Deborah A. DeManno, Angela Atwood, Mary Hunzicker-Dunn,

20808 The single-stranded DNA aptamer-binding site of hu-

and John D. Scott man thrombin. Lisa R. Paborsky, Sarah N . McCurdy, Linda C. Grzffzn, John J . Toole, and Lawrence L. K. Leung

20733 Correction of the class H defect in glycosylphosphati- dylinositol anchor biosynthesis in Ltk- cells by a human

20812 The inhibition by fatty acids of receptor-mediated cal-

cDNA clone. Tetsu Kamitani, Hu-Ming Chang, Carl Rollins, cium movements in Jurkat T-cells is due to increased calcium extrusion. Jean-Philippe Breittmayer, Claudette

Gerald L. Waneck, and Edward T. H. Yeh Pelassy, Jean-Louis Cousin, Alain Bernard, and Claude Aussel

20737 A GTP-dependent step in the activation mechanism of 20818 A thyrotrope-specific variant of Pit-1 transactivates

Hoth, and Reinhold Penner capacitative calcium influx. Cristina Fasolato, Markus the thyrotropin 6 promoter. Bryan R. Haugen, William M.

Wood, David F. Gordon, and E. Chester Rrdgway

* The CONTENTS arranged by Subject Categories will be found immediately following these CONTENTS. Full I ~ t r u c t i o ~ to Authors will be found in (1993) J. Biol. Chem. 268, 14543-14551, and reprints may be obtained from the editorial office.

... 111

V

20825 Substrate specificity characterization of a cdc2-like protein kinase purified from bovine brain. Katherine N . Beaudette, John Lew, and Jerry H. Wang

20831 The y subunit of the Escherichia coli F1-ATPase can be cross-linked near the glycine-rich loop region of a B subunit when ADP + M 8 + occupies catalytic sites but not when ATP + M$+ is bound. Robert Aggeler, Sui Xiong Cui, John F. W. Keana, Takeshi Koike, and Roderick A. Capaldi

20838 A role for the interchain disulfide or its participating 20958 thiols in the internalization of botulinum neurotoxin A revealed by a toxin derivative that binds to ecto-accep-

Anton de Paiua, Bernard Poulain, Gary W. Lawrence, Clifford tors and inhibits transmitter release intracellularly.

C. Shone, L a d i s l a w T a u , and J. Oliver Dolly 20966

20845 The regulation of phospholipase C-yl by phosphatidic acid. Assessment of kinetic parameters. Gwenith A. Jones and Graham Carpenter

20851 Receptor activation is distinct from hormone binding 20974

Aspse7 is important for receptor activation. Inhue J i and in intact lutropin-choriogonadotropin receptors and

Toe H. J i

20855 Folding of maltose-binding protein. Evidence for the 20983 identity of the rate-determining step in vivo and in vitro. Sang- Yearn Chun, Sharon Strobel, Philip Bassford, Jr., and Linda L. Randall

20863 Histidyl-proline diketopiperazine. Novel formation 20988 that does not originate from thyrotropin-releasing hor- mone. Kazuya Miyashita, Masami Murakami, Masanobu Ya- mada, Tokuji Iriuchijima, and Masatomo Mori

20997 20866 Transcriptional activation in yeast by the proline-rich

Robert G. Roeder activation domain of human CTF1. Tae Kook Kim and

21002 20870 Modulation by vitamin Ba of glucocorticoid receptor-

mediated gene expression requires transcription fac-

E. Allgood, Robert H. Oakley, and John A. Cidlowski tors in addition to the glucocorticoid receptor. Victoria

20937 Transit and sorting of apolipoprotein B within the en- doplasmic reticulum and Golgi compartments of iso- lated hepatocytes from normal and orotic acid-fed rats. Ian J. Cartwright, Abdel-Malik Hebbachi, and Joan A. Higgins

20953 Small-angle x-ray scattering studies of the iron-molyb- denum cofactor from Azotobacter vinelandii nitrogen- ase. David Eliezer, Patrick Frank, Nanna Gillis, William E. Newton, Sebastian Doniach, and Keith 0. Hodgson

Riboflavin 3’- and 5’-sulfate, two novel flavins accu- mulating in the roots of iron-deficient sugar beet (Beta vulgaris). Santos Susin, Joaquin Abian, Francisco Sun- chez-Baeza, M. Luisa Peleato, Anunciacwn Abadia, Emilio Gelpi, and Jauier Abadia

Calcium plays distinctive structural roles in the N- and C-terminal domains of cardiac troponin C. Rui M. M. Brito, George A. Krudy, Judy C. Negele, John A. Putkey, and Paul R. Roseuear

Relationship of low affinity [’Hlryanodine binding sites to high affinity sites on the skeletal muscle Caz+ release channel. Jian Ping Wang, Dolores H. Needleman, and Susan L. Hamilton

Translocation of Rac correlates with NADPH oxidase activation. Evidence for equimolar translocation of ox-

Loetterle, Algirdas J . Jesaitis, and Gary M. Bokoch idase components. Mark 2’. Quinn, Tony Euans, Linda R.

The disulfide folding pathway of hirudin elucidated by stop/go folding experiments. Benoit Chatrenet and Jui- Yo0 C h n g

Transition state stabilization by chloramphenicol ace-

onine 174. Ann Lewendon and William V. Shaw tyltransferase. Role of a water molecule bound to thre-

A factor binding to the xenobiotic responsive element

loop-helix proteins, Ah receptor and Arnt. Natsuki Mat- (XRE) of P-4501A1 gene consists of at least two helix-

sushita, Kazuhiro Sogawa, Masatsugu E m , Akira Yoshida, and Yoshiaki Fujii-Kuriyama

20877 Identification of a DNA binding domain in simian virus 40 capsid proteins Vp2 and Vp3. Jared Cleuer, Dauid A.

21007 Hepatic polysomes that contain apoprotein B mRNA

Dean, and Harumi Kasamatsu have unusual physical properties. Xiaoli Chen, Janet D. Sparks, Zemin Yao, and Edward A. Fisher

20884

20892

20897

20904

20911

20917

20923

20930

An aspartic proteinase present in seeds cleaves Arabi- dopsis 2 S albumin precursors in vitro. Kathleen D’Hondt, Dirk Bosch, Jose Van Damme, Marc Goethals, Joel Vandekerckhoue, and Enno Krebbers

Cbr, an algal homolog of plant early light-induced pro-

Leuy, Tamar Tal, Auiu Shaish, and Ada Zamir teins, is a putative zeaxanthin binding protein. Haim

bumin wild-type and F102W mutant. Thomas L. Pauls, Metal binding properties of recombinant rat parval-

Isabelle Durussel, Jos A. Cor, Ian D. Clark, Arthur G. Szabo, Stephane M. Gag&, Brian D. Sykes, and Martin W. Berchtold

Dominant negative activity of an endogenous thyroid hormone receptor variant ( (~2) is due to competition for

A. Lazar binding sites on target genes. Deborah Katz and Mitchell

GTP binding to elongation factor eEF-2 unmasks a tryptophan residue required for biological activity. Dominique Guillot, Frumpis Penin, Attilio Di Pietro, Bruno Sontag, Jean-Pierre Lauergne, and Jean-Paul Reboud

A functional and degenerate pair of EF hands contains the very high affinity calcium-binding site of calbindin- Dz~K. Myron D. Gross, Mark Gosnell, Anthony Tsarbopoulos, and Willi Hunziker

Isolation and characterization of three Dictyostelium myosin-I isozymes. Sheu-Fen Lee and Graham P. C6t6

Labeling of lysine 492 with pyridoxal 5”phosphate in the sarcoplasmic reticulum Caz+-ATPase. Lysine 492 residue is located outside the fluorescein 5-isothiocya- nate-binding region in or near the ATP binding site. K a t w Yamagata, Takashi Daiho, and Tohru Kanazawa

21014

21021

21028

21035

21044

21053

2 1060

21066

Substrate specificity for normal but not mutationally activated variants of src family kinases. Oliver Sartor and Keith C. Robbins

Identification of a skeletal muscle-specific regulatory domain in the rat GLUT4/muscle-fat gene. Jeanne M. Richardson and Jeffrey E. Pessin

Novel lacto-ganglio type gangliosides with GMz-epitope in bovine brain which react with IgM from a patient of the amyotrophic lateral sclerosis-like disorder. Toru N a b , Kazuo Kon, Susumu Ando, Tadashi Miyatake, Nobu- hiro Yuki, Yu-Teh Li, Shigeki Furuya, and Yoshio Hirabayashi

Cloning, expression, and chromosomal localization of the mouse meprin 0 subunit. Carlos M. Gorbea, Petra Marc-

Nancy A. Jenkins, and Judith S. Bond hand, Weiping Jiang, Neal G. Copeland, Debra J . Gilbert,

A novel CDC2-related protein kinase from Leishmania mexicana, LmmCRK1, is post-translationally regu-

Kinnaird, Brian R. Shiels, Andrew Tait, and J . David Barry lated during the life cycle. Jeremy C. Mottram, Jane H.

Characterization of interleukin-10 receptors on human and mouse cells. Jimmy C. Tan, Stephen R. Indelicato, Satwant K. Narula, Paul J . Zauodny, and Chuan-Chu Chou

Protein kinase C and the regulation of glutamate exo- cytosis from cerebrocortical synaptosomes. Eleanor 2’. Coffey, Taluinder S. Sihra, and David G. Nicholls

Interleukin- 1-induced signaling in T-cells. Evidence for the involvement of phosphatases PP1 and PP2A in regulating protein kinase C-mediated protein phos-

Annette Heiner, Klaus Resch, and Marta Szamel phorylation and interleukin-2 synthesis. Michael Kracht,

Baltimore, MD 21202, U.S.A. Volume 268 for 1993 United States, $710; other countries, $860. Single copy: United States, $24.00; other countries, $28.00. Special subscription & The J o u r d of Biological Chemistry (ISSN 0021-9258) is published three times per month hy the American Society for Biochemistry and Molecular Biology, Inc., 428 East Preston Street

avadable to members, eaduate students, and postdoctoral fellows for personal use only, Qualifying forms are available from the ASBMB Office, 9650 Rockville pike, Bethe&, MD 20814. Second class posta e pald at Baltimore, MD 21202, U.S.A. and at additional mailing offices. Printed in the U S A . Send address changes to The Journal o/ Eiobgicd Chemistry at 428 East Preston Street, Baftimore, MD 21202, U.S.A.

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21102

21113

21120

21130

21137

21147

21155

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21172

21185

21193

21198

21205

21212

21218

Regulation of epidermal growth factor receptor in

tibodies. Zhen Fan, John Mendelsohn, Hide0 Masui, and NIH3T3/HER14 cells by antireceptor monoclonal an-

Rakesh Kumar

Conformational changes in fibrinogen elicited by its interaction with platelet membrane glycoprotein GPIIb-IIIa. Tatiana P. Ugaroua, Andrei Z. Budzynski, San- ford J . Shattil, Zauerw M. Ruggeri, Mark H. Ginsberg, and Edward F. Plow

In situ characterization of a gymnosperm lignin. Lignification in cell suspension cultures of Pinus taeda.

Thomas L. Eberhardt, Mark A. Bernards, Lanfang He, b u r - ence B. Daum, Jan B. Wooten, and Norman G. Lewis

Regulation by phorbol esters of amyloid precursor pro- tein release from Swiss 3T3 fibroblasts overexpressing protein kinase Cu. Barbara E. Slnck, Roger M. Nitsch, Etta Liuneh, George M. Kunz, Jr., Jeffrey Breu, Hagit Eldar, and Richard J. Wurtmun

Molecular and cellular characterization of Mex-/meth-

serum dependence, and tumor suppression of transfec- ylation-resistant phenotype. Gene and cDNA cloning,

tant strains. Gerhard Fritz, J o g Dosch, Heinz W. Thielmann, and Bernd Kaina

Complete coding sequence, intron/exon organization, and chromosomal location of the gene for the core I

Guy G. Hoffman, Seungbok Lee, Angela M. Christiam, Linda protein of human ubiquinol-cytochrome c reductase.

and Daniel S. Greenspan C. Chung-Honet, Wen Cheng, Stacy Katchman, Jouni Uitto,

Macrophage nitric oxide synthase subunits. Purifica- tion, characterization, and role of prosthetic groups and

enzyme. Kwang J in Baek, Bonnie A. Thiel, Shawn Lucas, and substrate in regulating their association into a dimeric

Dennis J. Stuehr

Characterization of two forms of human factor Va with

M. Christella L. G. D. Thomassen, H. Coenrand Hemker, and different cofactor activities. Jan Rosing, Harry M. Bakker,

Guido Tans

Interaction of high mobility group-I(Y) nonhistone pro-

and Mark s. Nissen teins with nucleosome core particles. Raymond Reeves

man serum response factor contains DNA-activated The carboxyl-terminal transactivation domain of hu-

protein kinase phosphorylation sites. Shu-Hui Liu,

Anderson, and Sun-Yu Ng Jing-Tyan Ma, A. Yueh Yueh, Susan P. Lees-Miller, Carl W.

Yeast MCKl protein kinase autophosphorylates at ty-

strates at serine and threonine. Moon-Young Lim, Dauid rosine and serine but phosphorylates exogenous sub-

Dailey, G. Steuen Martin, and Jeremy Thorner

A comparative study of the chymotrypsin-like activity of the rat liver multicatalytic proteinase and the ClpP from Escherichia coli. Joaquin Arribas and Jose G. Castario

Signal transduction through the CD19 receptor during discrete developmental stages of human B-cell ontog- eny. Fatih M. Uckun, Anne L. Burkhardt, Lisa Jaruis, Xi00 Jun, Becky Stealey, Ilker Dibirdik, Dorothea E. Myers, Lisa Tuel-Ahlgren, and Joseph B. Bolen

Cas+-dependent and thapsigargin-inhibited phos-

lowing chimeric recombination with Ca2+-ATPase. Car- phorylation of Na+,K*-ATPase catalytic domain fol-

Kunio Takeyasu, Y . Feng, and Doughs M. Fambrough lota Sumbilla, Li Lu, David E. Lewis, Giuseppe Inesi, T. Ishii,

Mapping of the a-actinin binding site within the 81 integin cytoplasmic domain. Carol A. Otey, Gregory B. Vasquez, Keith Burridge, and Bruce W. Erickson

A growth factor-inducible gene encodes a novel nuclear protein with zinc finger structure. J . Albert Fernan- dez-Pol, Dennis J . Klos, and Paul D. Hamilton

Ubiquitin metabolism in cycling Xenopus egg extracts. Dauid Mahaffey, Yung Yoo, and Martin Rechsteiner

factor on lung regeneration after acute lung injury. Hepatocyte growth factor may act as a pulmotrophic

Kimihiko Yanagita, Kunio Matsumoto, Kiyoshi Sekiguchi, Hi- romi Ishibashi, Yoshiyuki N i b , and Toshikazu Nakamura

glycosylase from HeLa cells. Petra Neddermann and Josef The purification of a mismatch-specific thymine-DNA

Jiricny

21225

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21238

21246

21253

21263

21271

21276

21284

21293

21301

21309

21318

21328

21335

21344

21351

21359

21364

Transactivation by the human T-cell leukemia virus tax protein is mediated through enhanced binding of activating transcription factor-2 (ATF-8) ATF-8 re- sponse and CAMP element-binding protein (CREB). AU-

Anne Brauweiler, Pongsak Utaisincharoen, Maura-Ann H. drey A. Franklin, Mark F. Kubik, Martine N. Uittenbogaard,

Matthews, William S. Dynan, James P. Hoeffler, and Jennifer K. Nyborg

Deletion of a large domain in recombinant human pro- collagen I1 does not alter the thermal stability of the

Ala-Kokko, and Darwin J. Prockop triple helix. Aleksander L. Sieron, Andrzej Fertala, Leena

The interaction of the von Willebrand factor-A1 do-

cosylation and disulfide bonding in a monomeric recom- main with platelet glycoprotein Ib/IX. The role of gly-

binant A1 domain protein. Miguel A. Cruz, Robert I. Han- din, and Robert J . Wise

Engagement of specific sites in the plastoquinone niche regulates degradation of the D l protein in photosystem 11. Marcel A. K. Jansen, Brigitte Depka, Achim Trebst, and Marvin Edelman

RNA binding properties of vaccinia virus capping en- zyme. Yan Luo and Stewart Shuman

The cytoplasmic domain of the H-2Ld class I major histocompatibility complex molecule is differentially accessible to immunological and biochemical probes

Martha C. Zurliga during transport to the cell surface. G. George Capps and

Inhibition of colony-stimulating factor-1 promoter ac- tivity by the product of the Wilms’ tumor locus. Maureen A. Harrington, Bruce Konicek, A n Song, Xiao-ling Xia, William J . Frederick, and Frank J . Rauscher, III

Novel isozymes of CAMP-dependent protein kinase ex- ist in human cells due to formation of RIa-RIB hetero- dimeric complexes. Kjetil Tasken, B j ~ n Steen SkAlhegg, Rigmor Solberg, Kristin Breuik Andersson, Susan S. Taylor, Tor Lea, Heidi Kiil Blomhoff, Tore Jahnsen, and Vidar Hans- son

Factor XIIIa-derived peptides inhibit transglutaminase activity. Localization of substrate recognition sites. Ko- mandoor E. Achyuthan, Thomas F. Slaughter, Manuel A. Santiago, Jan J. Enghild, and Charles S. Greenberg

Characterization of a human DNA damage binding pro- tein implicated in xeroderma pigmentosum E. Scott Kee- ney, George J. Chang, and Stuart Linn

Comparative analysis of binding of human damaged DNA-binding protein (XPE) and Escherichia coli dam-

photoproducts: T[c,s]T, T[T,s]T, T[6-4]T, and age recognition protein (UvrA) to the major ultraviolet

T[Dewar]T. Joyce T. Reardon, Anne F. Nichols, Scott Kee-

Azzz Sancar my, Colin A. Smith, John-Stephen Taylor, Stuart Linn, and

Quantitation of peptide anchor residue contributions to class I major histocompatibility complex molecule bind- ing. Yutaka Saito, Per A. Peterson, and Masazumi Matsumura

Purification, molecular cloning, and sequencing of phospholipase C-84. Chang-Won Lee, Do Joon Park, Kweon-Haeng Lee, Chan Gil Kim, and Sue Goo Rhee

Function of the hydrophilic carboxyl terminus of type

I. In vitro studies. Donna Greenwood Crenshaw and I1 DNA topoisomerase from Drosophila rnelanogaster.

Tao-shih Hsieh

Function of the hydrophilic carboxyl terminus of type I1 DNA topoisomerase from Drosophila rnelanogaster. 11. In vivo studies. Donna Greenwood Crenshaw and Tao-shih Hsieh

hps 70-like protein in rhesus erythrocyte cytosol and its interactions with membrane skeleton under heat and pathologic stress. Tanima Gudl and Chhitar M. Gupta

Expression and structural analysis of a teleost homolog of a mammalian zona pellucida gene. Catherine E. Lyons, Kim L. Payette, Jeffrey L. Price, and Ru Chih C. H u n g

Coproporphyrinogen oxidase. Purification, molecular cloning, and induction of mRNA during erythroid dif- ferentiation. Hirao Kohno, Takako Furukawa, Take0 Yosh- inaga, Rikio Tokunuga, and Shigeru Taketani

The epithelial sialomucin, episialin, is sialylated during recycling. Sergey V. Lituinou and John Hilkens

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Characterization of a new RNA helicase from nuclear extracts of HeLa cells which translocates in the 5’ to 3‘ direction. Hernan Fkwes-Rozas and Jerard Hurwitz

Horseshoe crab coagulation factor B. A unique serine protease zymogen activated by cleavage of an Ile-Ile bond. Tatsushi Muta, Toshw Oda, and Sadaaki Iwanaga

Position-specific Asp-Lys pairing can affect signal se- quence function and membrane protein topology. Helena Andersson and Gunnar won Heijne

Purification and characterization of endothelin-con- verting enzyme from rat lung. Masaaki Takahahi, Youi- chi Matsmhita, Yasuteru Iijimn, and Kazuhikn Tanzawa

Core glycosylation of cytochrome P-45O(arom). Evi- dence for localization of N terminus of microsomal cytochrome P-450 in the lumen. Okura Shimozawa, Masao

Mihura, and Tsuneo Omura Sakaguchi, Hisamitsu Ogawa, Nobuhiro Harada, Katsuyoshi

lesterol acyltransferase activation. Structure:function Apolipoprotein A-I domains involved in lecithin-cho-

Jason P. Lee relationships. Mary Sorci-Thomas, Mary W. Kearns, and

Association of protein kinases ERKl and ERK2 with p75 nerve growth factor receptors. Cinzia Volonti, James M. Angelastro, and Lloyd A. Greene

Phosphatidylserine decarboxylase from Saccharomy- ces cereuisiae. Isolation of mutants, cloning of the gene, and creation of a null allele. Pamela J. Trotter, J o h n Pedretti, and Dennis R. Voelker

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Structure and function of a membrane anchor-less form of the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus. Anne M. Mirza, John P. Sheehan, Larry W. Hardy, Rhona L. Glickman, and Ronald M. Iorio

Characterization of the receptor responsible for throm- bin-induced intracellular calcium responses in osteo- blast-like cells. Alison L. Jenkins, Martin D. Bootman, Colin W. Taylor, Eleanor J. Mackie, and Stuart R. Stone

Effects of 5-fluorouracil substitution on the RNA con- formation and in vitro translatlon of thymidylate syn- thase messenger RNA. Chrls H. Takzmoto, Donna B. Voeller, John M. Strong, Larry Anderson, E d Chu, and Carmen J. Allegra

Enhanced phosphorylation and dephosphorylation of a histone-like protein in response to hyperosmotic and

and Eugene G. h u m hypoosmotic conditions. Lydia Santell, Robert L. Rubin,

Release from GI growth arrest by transforming rowth factor 81 requires cellular raa activity. Philip if Howe, Steven F. Dobrowolski, Kumar B. Reddy, and Dennls W. Stacey

ADDITIONS AND CORRECTIONS Identification of a novel serum and growth factor-in- ducible gene in vascular smooth muscle cells. Vol. 268 (1993) 9387-9392. Ping Feng and Gene Lzau

Identification and purification of a yeast rotein that affects elongation by RNA olymerase If. Vol. 266

David H. Price (1991) 9256-9262. Davzd R. (%fin, Tracl J. Claussen, and

Regulation of human NAD P)H:quinone oxidoreduc- tase gene. Role of A P 1 binding slte contained within human antioxidant response element. Vol. 267 (1992) 15097-15104. Yzng Lz and And K. Jazswal

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Vol. 268, No. 28

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The Journal of Biological Chemistry

CONTENTS Arranged by Subject Categories

October 5, 1993

MINIREVIEW

Edelman and Frederick S. Jones Outside and downstream of the homeobox. Gerald M.

CARBOHYDRATES, LIPIDS, AND OTHER NATURAL PRODUCTS

Histidyl-proline diketopiperazine. Novel formation that does not originate from thyrotropin-releasing hor- mone. Kazuya Miyashita, Masami Murakami, Masanobu Ya- mada, Tokuji Iriuchijima, and Masatomo Mori

Novel lacto-ganglio type gangliosides with GMz-epitope in bovine brain which react with IgM from a patient of the amyotrophic lateral sclerosis-like disorder. Toru Nakao, Kazuo Kon, Susumu Ando, Tadashi Miyatake, Nobu- hiro Yuki, Yu-Teh Li, Shigeki Furuya, and Yoshio Hirabayashi

Lignification in cell suspension cultures of Pinus taeda. I n situ characterization of a gymnosperm lignin. Thomas L. Eberhardt, Mark A. Bernards, Lanfang He, Laur- ence B. Dauin, Jan B. Wooten, and Norman G. Lewis

Phosphatidylserine decarboxylase from Saccharomy- ces cereuisiae. Isolation of mutants, cloning of the gene, and creation of a null allele. Pamela J. Trotter, John Pedretti, and Dennis R. Voelker

CELL BIOLOGY AND METABOLISM Potent inhibition of human tumor p2 1" farnesyltrans-

Meenakshi Nigam, Churl-Min Seong, Yimin Qian, Andrew D. ferase byAlA2-lacking p21" CAIAyYpeptidomimetics.

Hamilton, and Said M. Sebti

Stimulation of tyrosine phosphorylation and accumu- lation of GTP-bound p21- upon antibody-mediated a261 integrin activation in T-lymphoblastic cells. Car- olyn Kapron-Bras, Linda Fitz-Gibbon, Premala Jeeuaratnam, John Wilkins, and Shoukat Dedhar

Arachidonic acid release from aortic smooth muscle cells induced by [Ar$]vasopressin is largely mediated by calcium-independent phospholipase Az. John J. Leh-

and Richard W. Gross man, Kathryn A. Brown, Sasanka Ramanadham, John Turk,

Lysophosphatidic acid stimulates mitogen-activated protein kinase activation via a G-protein-coupled path- way requiring p21" and ~74'"'. Louise R. Howe and Christopher J . Marshall

Lipopolysaccharide induces activation of CDJ4-asso- ciated protein tyrosine kinase p53/56lY". Irena Stefanoua, Marta L. Corcoran, Eva M. Horak, Larry M. Wahl, Joseph B. Bolen, and Ivan D. Horak

capacitative calcium influx. Cristinu Fasolato, Markus A GTP-dependent step in the activation mechanism of

Hoth, and Reinhold Penner

Substituting isoserine for serine in the thrombin recep- tor activation peptide SFLLRN confers resistance to aminopeptidase "induced cleavage and inactivation. Barry S. Coller, Karen T. Springer, Lesley E. Scudder, Jeffery L. Kutok, Marco Ceruso, and Glenn D. Prestwich

Molecular cloning and functional expression of human acyl-coenzyme A:cholesterol acyltransferase cDNA in mutant Chinese hamster ovary cells. Catherine C. Y. Chang, Ho Young Huh, Kenneth M. Cadigan, and Ta Yuun Chang

Two-dimensional, rotational-echo double-resonance NMR of cell culture metabolism. Lynda M. McDowell, Eric R. Cohen, and Jacob Schuefer

Related signals for endocytosis and basolateral sorting of the asialoglycoprotein receptor. Iris Geffen, Christian Fuhrer, Birgit Leitinger, Martina Weiss, Katja Huggel, Gillian Griffiths, and Martin Spiess

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20937

20958

20983

21021

21044

21060

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21073

21097

21137

21147

21172

21193

21198

Characterization of the third member of the MCAT family of cationic amino acid transporters. Identifica- tion of a domain that determines the transport proper-

Lyons, Carol Kelly, and James M. Cunningham ties of the MCAT proteins. Ellen Ildicho Closs, C. Richard

The inhibition by fatty acids of receptor-mediated cal-

calcium extrusion. Jean-Philippe Breittmayer, Claudette cium movements in Jurkat T-cells is due to increased

Pelossy, Jean-Louis Cousin, Ah in Bernard, and Claude Aussel

dopsis 2 S albumin precursors in uitro. Kathleen An aspartic proteinase present in seeds cleaves Arabi-

D'Hondt, Dirk Bosch, Jose Van Damme, Marc Goethals, Joel Vandekerckhoue, and Enno Krebbers

Transit and sorting of apolipoprotein B within the en- doplasmic reticulum and Golgi compartments of iso-

Ian J . Cartwright, Abdel-Malik Hebbachi, and Joan A. Higgins lated hepatocytes from normal and orotic acid-fed rats.

Riboflavin 3'- and 5'-sulfate, two novel flavins accu- mulating in the roots of iron-deficient sugar beet (Beta

chez-Baeza, M. Luisa Peleato, Anunciacion Abadia, Emilio uulgaris). Santos Susin, Joaquin Abian, Francisco San-

Gelpi, and Jauier Abadia

Translocation of Rac correlates with NADPH oxidase activation. Evidence for equimolar translocation of ox- idase components. Mark T. Quinn, Tony Euans, Linda R. Loetterle, Algirdas J . Jesaitis, and Gary M. Bokoch

Identification of a skeletal muscle-specific regulatory domain in the rat GLUTl/muscle-fat gene. Jeanne M. Richardson and Jeffrey E. Pessin

A novel CDC2-related protein kinase from Leishmania mexicana, LmmCRK1, is post-translationally regu-

Kinnaird, Brian R. Shiels, Andrew Tait, and J . David Barry lated during the life cycle. Jeremy C. Mottram, Jane H.

Protein kinase C and the regulation of glutamate exo- cytosis from cerebrocortical synaptosomes. Eleanor T. Coffey, Taluinder S. Sihra, and David G. Nicholls

Interleukin-1-induced signaling in T-cells. Evidence for the involvement of phosphatases PP1 and PP2A in regulating protein kinase C-mediated protein phos-

Annette Heiner, Klaus Resch, and Marta Szamel phorylation and interleukin-2 synthesis. Michael Kracht,

Regulation of epidermal growth factor receptor in NIH3T3/HER14 cells by antireceptor monoclonal an-

Rakesh Kumar tibodies. Zhen Fan, John Mendelsohn, Hideo Masui, and

Regulation by phorbol esters of amyloid precursor pro- tein release from Swiss 3T3 fibroblasts overexpressing protein kinase Ca. Barbara E. Slack, Roger M. Nitsch, Etta Liuneh, George M. Kunz, Jr., Jeffrey Breu, Hagit Eldar, and Richard J. Wurtman

Interaction of high mobility group-I(Y) nonhistone pro-

and Mark S. Nissen teins with nucleosome core particles. Raymond Reeves

The carboxyl-terminal transactivation domain of hu- man serum response factor contains DNA-activated protein kinase phosphorylation sites. Shu-Hui Liu,

Anderson, and Sun-Yu Ng Jing-Tyan Ma, A. Yueh Yueh, Susan P. Lees-Miller, Carl W.

Signal transduction through the CD19 receptor during discrete developmental stages of human B-cell ontog- eny. Fatih M. Uckun, Anne L. Burkhardt, Lisa Jaruis, Xiao Jun, Becky Stealey, Ilker Dibirdik, Dorothea E. Myers, Lisa Tuel-Ahlgren, and Joseph B. Bolen

Mapping of the a-actinin binding site within the 81 integrin cytoplasmic domain. Carol A. Otey, Gregory B. Vasquez, Keith Burndge, and Bruce W. Erickson

A growth factor-inducible gene encodes a novel nuclear protein with zinc finger structure. J. Albert Fernan- dez-Pol, Dennis J . Klos, and Paul D. Hamilton

9 Indicates a Communication

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21218

Ubiquitin metabolism in cycling Xenopus egg extracts. David Mahaffey, Yung Yoo, and Martin Rechsteiner

Hepatocyte growth factor may act as a pulmotrophic factor on lung regeneration after acute lung injury. Kimihiko Yanngita, Kunw Matsumoto, Kiyoshi Sekiguchi, Hi- rami Ishibashi, Yoshiyuki Niho, and Toshikazu Nakamura

The cytoplasmic domain of the H-2Ld class I major histocompatibility complex molecule is differentially accessible to immunological and biochemical probes during transport to the cell surface. G. George Capps and Martha C. Zuriiga

Core glycosylation of cytochrome P-450(arom). Evi- dence for localization of N terminus of microsomal cytochrome P-450 in the lumen. Okura Shimozawa, Masao Sakaguchi, Hisamitsu Ogawa, Nobuhiro Harada, Katsuyoshi Mihara, and Tsuneo Omura

Association of protein kinases ERKl and ERK2 with

M. Angelastro, and Lloyd A. Greene p75 nerve growth factor receptors. Cinzia Volont6, James

bin-induced intracellular calcium responses in osteo- Characterization of the receptor responsible for throm-

blast-like cells. Alison L. Jenkins, Martin D. Bootman, Colin W. Taylor, Eleanor J . Mackie, and Stuart R. Stone

Enhanced phosphorylation and dephosphorylation of a histone-like protein in response to hyperosmotic and hypoosmotic conditions. Lydia Santell, Robert L. Rubin, and Eugene G. Leuin

factor 81 requires cellular ras activity. Philip H. Howe, Release from GI growth arrest by transforming growth

Steuen F. Dobrowolski, Kumar E. Reddy, and Dennis W. Stacey

ENZYMOLOGY Biosynthesis of heparinbeparan sulfate. Identification of a 70-kDa protein catalyzing both the D-glUCUrOn0- syl- and the N-acetyl-D-glucosaminyltransferase reac- tions. Thomas Lind, Ul/ Lindahl, and Kerstin Lidholt

complex with L(+)-tartrate. Ylua Lindquist, Gunter Schnei- Three-dimensional structure of rat acid phosphatase in

der, and Pirkko Vihko

Role of the interdomain linker peptide of Trichoderma reesei cellobiohydrolase I in its interaction with crys-

Merja Penttilii, and Tuuln T. Terri talline cellulose. Malee Srisodsuk, Tapani Reinikainen,

Aspso‘ of Escherchia coli acid phosphatase is involved in leaving group protonation. Kirill Ostanin and Robert L. Van Etten

Substrate specificity characterization of a cdc2-like protein kinase purified from bovine brain. Katherine N. Beaudette, John Lew, and Jerry H. Wang

acid. Assessment of kinetic parameters. Gwenith A. Jones The regulation of phospholipase C-yl by phosphatidic

and Graham Carpenter

Isolation and characterization of three Dictyostelium myosin-I isozymes. Sheu-Fen Lee and Graham P. Cbti

Transition state stabilization by chloramphenicol ace- tyltransferase. Role of a water molecule bound to thre- onine 174. Ann Lewendon and William V. Shaw

Macrophage nitric oxide synthase subunits. Purifica- tion, characterization, and role of prosthetic groups and substrate in regulating their association into a dimeric enzyme. Kwang J in Baek, Bonnie A. Thiel, Shawn Lucas, and Dennis J . Stuehr

Yeast MCKl protein kinase autophosphorylates at ty- rosine and serine but phosphorylates exogenous sub- strates at serine and threonine. Moon- Young Lim, D a d Dailey, G. Steven Martin, and Jeremy Thorner

A comparative study of the chymotrypsin-like activity of the rat liver multicatalytic proteinase and the ClpP from Escherichia coli. Joqu in Arribas and Jose G. Castario

The purification of a mismatch-specific thymine-DNA

Jiricny glycosylase from HeLa cells. Petra Neddermann and Josef

21318 Purification, molecular cloning, and sequencing of phospholipase C-04. Chung-Won Lee, Do Joon Park, Kweon-Haeng Lee, Chan Gil Kim, and Sue Goo Rhee

21359 Coproporphyrinogen oxidase. Purification, molecular cloning, and induction of mRNA during erythroid dif- ferentiation. Hirao Kohno, Takako Furukawa, Takeo Yosh- inaga, Rikw Tokunaga, and Shigeru Taketani

21394 Purification and characterization of endothelin-con- verting enzyme from rat lung. Masaaki Takahashi, Youi- chi Matsushita, Yasuteru Iijima, and Kazuhiko Tanzawa

MEMBRANES AND BIOENERGETICS 20762 Glutamine 170 to tyrosine substitution in yeast mito-

chondrial F1 &subunit increases catalytic site interac- tion with GDP and IDP and produces negative cooper- ativity of GTP and ITP hydrolysis. Jean-Michel Jault, Gilles Diuita, William S. Allison, and Attilio Di Pietro

20785 Influence of nucleotide binding site occupancy on the thermal stability of the F, portion of the chloroplast ATP synthase. Zhen-Yuan Wang, Ernesto Freire, and Rich- ard E. McCarty

20831 The y subunit of the Escherichia coli F1-ATPase can be cross-linked near the glycine-rich loop region of a ,9 subunit when ADP + Mg2+ occupies catalytic sites but not when ATP + Mg2+ is bound. Robert Aggeler, Sui Xiong Cai, John F. W. Keana, Takeshi Koike, and Roderick A. Capaldi

20892 Cbr, an algal homolog of plant early light-induced pro- teins, is a putative zeaxanthin binding protein. Haim Leuy, Tamar Tal, Auiu Shaish, and Ada Zamir

20930 Labeling of lysine 492 with pyridoxal 5”phosphate in the sarcoplasmic reticulum Ca2+-ATPase. Lysine 492 residue is located outside the fluorescein B-isothiocya- nate-binding region in or near the ATP binding site. Kazuo Yamagata, Takashi Daiho, and Tohru Kanazawa

20974 Relationship of low affinity [3H]ryanodine binding sites

channel. Jian Ping Wang, Dolores H. Needleman, and Susan to high affinity sites on the skeletal muscle Ca2+ release

L. Hamilton

21185 Ca2+-dependent and thapsigargin-inhibited phos- phorylation of Na+,K+-ATPase catalytic domain fol- lowing chimeric recombination with CaZ+-ATPase. Car-

Kunio Takeyasu, Y. Feng, and Douglas M. Fambrough lota Sumbilln, Li Lu, David E. Lewis, Giuseppe Inesi, T. Ishii,

21344 hps 70-like protein in rhesus erythrocyte cytosol and its interactions with membrane skeleton under heat and pathologic stress. Tanima Gudi and Chhitar M. Gupta

21389 Position-specific Asp-Lys pairing can affect signal se-

Andersson and Gunnar won Heijne quence function and membrane protein topology. Helena

NUCLEIC ACIDS. PROTEIN SYNTHESIS. AND

020687

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020733

MOLECULAR GENETICS ~ - z

A helix-loop-helix transcription factor-like gene is lo-

Joan M. Krakowsky, and Kathleen P. Anderson cated at the mi locus. Michael J . Hughes, Jerly B Lingrel,

Molecular piracy of mammalian interleukin-8 receptor type B by herpesvirus saimiri. Sunil K. Ahuja and Philip M. Murphy

Preferential binding of histone H1 to four-way helical junction DNA. Patrick Varga- Weisz, Kensal wan Holde, and Jordanka Zlatanoua

The p27 catalytic subunit of the apolipoprotein B mRNA editing enzyme is a cytidine deaminase. Na- ueenun Nauaratnam, John R. Morrison, Shoumo Bhatta-

Ea-Bie Teng, Nicholas 0. Dauidson, and James Scott charya, Dipti Patel, Toru Funahashi, Federico Giannoni,

Interaction between a complex of RNA polymerase 111 subunits and the 70-kDa component of transcription factor IIIB. Michel Werner, Nathalie Chussiuert, Ian M. Willis, and Andre Sentenac

Correction of the class H defect in glycosylphosphati- dylinositol anchor biosynthesis in Ltk- cells by a human cDNA clone. Tetsu Kamitani, Hu-Ming Chang, Carl Rolbns, Gerald L. Waneck, and Edward T. H. Yeh

Indicates a Communication

X

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20911

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21007

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21328

Cloning and characterization of the gene encoding the human platelet glycoprotein V. A member of the leu- cine-rich glycoprotein family cleaved during thrombin- induced platelet activation. Frawois Lanza, Martine Mo- rales, Corinne de La Salk, Jean-Pierre Cazenave, Kenneth J. Clemetson, Takeshi Shimomura, and David R. Phillips

A thyrotrope-specific variant of Pit-1 transactivates the thyrotropin 6 promoter. Bryan R. Haugen, William M. Wood, David F. Gordon, and E. Chester Ridgway

activation domain of human CTF1. Tae Kook Kim and Transcriptional activation in yeast by the proline-rich

Robert G. Roeder

mediated gene expression requires transcription fac- Modulation by vitamin Be of glucocorticoid receptor-

tors in addition to the glucocorticoid receptor. Victoria E. Allgood, Robert H. Oakley, and John A. Cidlowski

Dominant negative activity of an endogenous thyroid

binding sites on target genes. Deborah Katz and Mitchell hormone receptor variant (a2) is due to competition for

A. Lazar

GTP binding to elongation factor eEF-2 unmasks a

Dominique Guillot, Frawois Penin, Attilio Di Pietro, Bruno tryptophan residue required for biological activity.

Sontag, Jean-Pierre Luvergne, and Jean-Paul Reboud

A factor binding to the xenobiotic responsive element

loop-helix proteins, Ah receptor and Arnt. Natsuki Mat- (XRE) of P-4501A1 gene consists of at least two helix-

sushita, Kazuhiro Sogawa, Masatsugu Emu, Akira Yoshida, and Yoshiaki Fujii-Kuriyamu

Hepatic polysomes that contain apoprotein B mRNA have unusual physical properties. Xiaoli Chen, Janet D. Sparks, Zemin Yao, and Edward A. Fisher

Substrate specificity for normal but not mutationally activated variants of arc family kinases. Oliver Sartor and Keith C. Robbins

Molecular and cellular characterization of Mex-/meth- ylation-resistant phenotype. Gene and cDNA cloning, serum dependence, and tumor suppression of transfec-

and Bernd Kaina tant strains. Gerhard Fritz, Jorg Dosch, Heinz W. Thielmunn,

Complete coding sequence, intron/exon organization,

protein of human ubiquinol-cytochrome c reductase. and chromosomal location of the gene for the core I

Guy G. Hoffman, Seungbok Lee, Angela M. Christiano, Linda C. Chung-Honet, Wen Cheng, Stacy Katchman, Jouni Uztto, and Danrel S. Greenspan

Transactivation by the human T-cell leukemia virus tax protein is mediated through enhanced binding of activating transcription factor-2 (ATF-2) ATF-2 re- sponse and CAMP element-binding protein (CREB). Au- drey A. Franklin, Mark F. Kubik, Martine N . Uittenbogmrd, Anne Brauweiler, Pongsak Utaisincharoen, Maura-Ann H. Matthews, William S. Dynan, James P. Hoeffler, and Jennifer K. Nyborg

RNA binding properties of vaccinia virus capping en- zyme. Yan Luo and Stewart Shuman

Inhibition of colony-stimulating factor-1 promoter ac-

A. Harrington, Bruce Konicek, A n Song, Xiao-ling Xia, William tivity by the product of the Wilms’ tumor locus. Maureen

J. Frederick, and Frank J . Rauscher, III

Characterization of a human DNA damage binding pro- tein implicated in xeroderma pigmentosum E. Scott Kee- my , George J . Chang, and Stuart Linn

Comparative analysis of binding of human damaged DNA-binding protein (XPE) and Escherichia coli dam- age recognition protein (UvrA) to the major ultraviolet photoproducts: T[c,s]T, T[T,s]T, T[6-4lT, and T[Dewar]T. Joyce T. Reardon, Anne F. Nichols, Scott Kee-

Azrz Sancar ney. Colin A. Smith, John-Stephen Taylor, Stuart Linn, and

Function of the hydrophilic carboxyl terminus of type I1 DNA topoisomerase from Drosophila rnelanogaster. I. In vitro studies. Donna Greenwood Crenshaw and Tao-shih Hsieh

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21372

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21453

21454

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Function of the hydrophilic carboxyl terminus of type I1 DNA topoisomerase from Drosophila rnelanogaster. 11. In vivo studies. Donna Greenwood Crenshaw and Tao-Shih Hsieh

Expression and structural analysis of a teleost homolog of a mammalian zona pellucida gene. Catherine E. Lyons, Kim L. Payette, Jeffrey L. Price, and Ru Chih C. Huang

The epithelial sialomucin, episialin, is sialylated during recycling. Sergey V . Litvinov and John Hilkens

Characterization of a new RNA helicase from nuclea: extracts of HeLa cells which translocates in the 5’ to 3 direction. Hernan Flares-Rozas and Jerard Hurwitz

Effects of 5-fluorouracil substitution on the RNA con- formation and in vitro translation of thymidylate syn- thase messenger RNA. Chris H. Takimoto, Donna B. Voeller, John M. Strong, Larry Anderson, Ed Chu, and Carmen J. Allegra

Identification of a novel serum and growth factor-in- ducible gene in vascular smooth muscle cells. Vol. 268 (1993) 9387-9392. Ping Feng and Gene Liau

Regulation of human NAD(P)H:quinone oxidoreduc- tase gene. Role of A P 1 binding site contained within human antioxidant response element. Vol. 267 (1992) 15097-15104. Ying Li and Ani1 K. Jaiswal

PROTEIN CHEMISTRY AND STRUCTURE Follicle-stimulating hormone regulation of A-kinase anchoring proteins in granulosa cells. Daniel W. Carr, Deborah A. DeManno, Angela Atwood, Mary Hunzicker-Dunn, and John D. Scott

Plasminogen activation stimulates an increase in intra- cellular calcium in human synovial fibroblasts. Mario Gonzalez-Gronow, Govind Gawdi, and Salvatore V. Pizzo

The single-stranded DNA aptamer-binding site of hu- man thrombin. Lisa R. Paborsky, Sarah N. McCurdy, Linda C. Griffin, John J. Toole, and Lawrence L. K. h u n g

A role for the interchain disulfide or its participating

revealed by a toxin derivative that binds to ecto-accep- thiols in the internalization of botulinum neurotoxin A

tors and inhibits transmitter release intracellularly. Anton de Paiva, Bernard Poulam, Gary W. Lawrence, Clifford C. Shone, Ladislav Tauc, and J . Oliver Dolly

Receptor activation is distinct from hormone binding in intact lutropin-choriogonadotropin receptors and Aspsg7 is important for receptor activation. Inhae J i and Tae H. J i

Folding of maltose-binding protein. Evidence for the identity of the rate-determining step in vivo and in vitro. Sang-Yearn Chun, Sharon Strobel, Philip Bassford, Jr., and Linda L. Randall

Identification of a DNA binding domain in simian virus

Dean, and Harumi Kasamatsu 40 capsid proteins Vp2 and Vp3. Jared Clever, David A.

Metal binding properties of recombinant rat parval- bumin wild-type and F102W mutant. Thomas L. Pauls, Isabelle Durussel, Jos A. Cox, Ian D. Clark, Arthur G. Szabo, StGphane M. Gag&, Brian D. Sykes, and Martin W. BerchtoM

A functional and degenerate pair of EF hands contains the very high affinity calcium-binding site of calbindin- DasK. Myron D. Gross, Mark Gosnell, Anthony Tsarbopoulos, and Willi Hunziker

denum cofactor from Arotobcrcter vinelandii nitrogen- Small-angle x-ray scattering studies of the iron-molyb-

Newton, Sebastian Donioch, and Keith 0. Hodgson ase. David Eliezer, Patrick Frank, Nanna Gillis, William E.

Calcium plays distinctive structural roles in the N- and C-terminal domains of cardiac troponin C. Rui M. M.

Paul R. Rosevear Brito, George A. Krudy, Judy C. Negek, John A. Putkey, and

The disulfide folding pathway of hirudin elucidated by stop/go folding experiments. Benoit Chatrenet and Jui- Yoa Chaw

Indicates a Communication

xi

21035 Cloning, expression, and chromosomal localization of the mouse meprin B subunit. Carlos M. Gorbea, Petra Marc- hand, Weiping Jiang, Neal G. Copeland, Debra J . Gilbert, Nancy A. Jenkins, and Judith S. Bond

21053 Characterization of interleukin-10 receptors on human and mouse cells. Jimmy C. Tan, Stephen R. Indelicato, Satwant K. Narula, Paul J . Zauodny, and Chwn-Chu Chou

21080 Conformational changes in fibrinogen elicited by its interaction with platelet membrane glycoprotein

ford J . Shattil, Zauerw M. Ruggeri, Mark H. Ginsberg, and GPIIb-IIIa. Tatiana P. Vgaroua, Andrei Z . Budzynski, San-

Edward F. Plow

21130 Characterization of two forms of human factor Va with different cofactor activities. Jan Rosing, Harry M. Bakker, M. Christella L. G. D. Thomassen, H. Coenraad Hemker, and Guido Tans

21232 Deletion of a large domain in recombinant human pro- collagen I1 does not alter the thermal stability of the

Ala-Kokko, and Darwin J . Prockop triple helix. Aleksander L. Sieron, Andrzej Fertala, Leena

21238 The interaction of the von Willebrand factor-A1 do- main with platelet glycoprotein Ib/IX. The role of gly- cosylation and disulfide bonding in a monomeric re- combinant A1 domain protein. Miguel A. Cruz, Robert I. Handin, and Robert J . Wise

21246 Engagement of specific sites in the plastoquinone niche regulates degradation of the D l protein in photosystem

Marvin Edelman 11. Marcel A. K. Jansen, Brigitte Depka, Achim Trebst, and

21276 Novel isozymes of CAMP-dependent protein kinase ex-

dimeric complexes. Kjetil Tasken, Bj6rn Steen Skiilhegg, ist in human cells due to formation of RIa-RIB hetero-

Rigmor Solberg, Kristin Breuik Andersson, Susan S. Taylor,

Hansson Tor Lea, Heidi Kiil Blomhoff, Tore Jahnsen, and Vidar

21284 Factor XIIIa-derived peptides inhibit transglutaminase activity. Localization of substrate recognition sites. Ko-

Santiago, Jan J. EnghiM, and Charles S. Greenberg mandoor E. Achyuthan, Thomas F. Slaughter, Manuel A.

21309 Quantitation of peptide anchor residue contributions to class I major histocompatibility complex molecule bind- ing. Yutaka Saito, Per A. Peterson, and Masazumi Matsumura

21384 Horseshoe crab coagulation factor B. A unique serine protease zymogen activated by cleavage of an Ile-Ile bond. Tatsushi Muta, Toshio Oda, and Sadaaki Iwanaga

21403 Apolipoprotein A-I domains involved in lecithin-cho- lesterol acyltransferase activation. Structure:function relationships. Mary Sorci-Thomas, Mary W. Kearns, and Jason P. Lee

21425 Structure and function of a membrane anchor-less form of the hemagglutinin-neuraminidase glycoprotein of

Larry W. Hardy, Rhona L. Glickman, and Ronald M. Iorio Newcastle disease virus. Anne M. Mirza, John P. Sheehan,

21454 Identification and purification of a yeast protein that affects elongation by RNA polymerase 11. Vol. 266

Daucd H. Price (1991) 9256-9262. Dauid R. Chafin, Traci J . Claussen, and

Ahadia, Anunciacibn, 20958

Abian, Joaquin, 20958 Ahadia, Javier, 20958

Achyuthan, Komandoor E.,

Ahuja, Sunil K., 20691 Aggeler, Robert, 20831

Ala-Kokko, Leena, 21232 Allegra, Carmen J., 21438 Allgood, Victoria E., 20870 Allison, William S., 20762

Anderson, Kathleen P., 20687 Anderson, Carl W., 21147

Anderson, Larry, 21438 Andersson, Helena, 21389 Andersson, Kristin Brevik,

Ando, Susumu, 21028 Angelastro, James M., 21410 Arrihas, Joaquin, 21165 Atwood, Angela, 20729 Aussel, Claude, 20812 Baek, Kwang Jin, 21120 Bakker, Harry M., 21130 Barry, J. David, 21044 Bassford, Philip, Jr., 20855 Beaudette, Katherine N.,

Berchtold, Martin W., 20897 Bernard, Alain, 20812 Bernards, Mark A,, 21088 Bhattacharya, Shoumo,

Blomhoff, Heidi Kiil, 21276 Bokoch, Gary M., 20983 Bolen, Joseph B., 20725,

Bond, Judith S., 21035 Bootman, Martin D., 21432 Bosch, Dirk, 20884 Brauweiler, Anne, 21225 Breittmayer, Jean-Philippe,

Breu, Jeffrey, 21097 Brito, Rui M. M., 20966 Brown, Kathryn A,, 20713 Budzynski, Andrei Z., 21080

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21276

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20709

21172

20812

Burkhardt, Anne L., 21172 Burridge, Keith, 21193 Cadigan, Kenneth M., 20747 Cai, Sui Xiong, 20831 Capaldi, Roderick A,, 20831 Cams. G. Georee. 21263 Carpenter, Graham, 20845 Carr, Daniel W., 20729 Cartwright, Ian J., 20937 Castaho, Jose G., 21165

Ceruso, Marco, 20741 Cazenave, Jean-Pierre, 20801

Chafin, David R., 21454 Chang, Catherine C. Y.,

Chang, George J., 21293 Chang, Hu-Ming, 20733 Chang, Jui-Yoa, 20988 Chang, Ta Yuan, 20747 Chatrenet, Benoit, 20988 Chaussivert, Nathalie, 20721 Chen, Xiaoli, 21007 Cheng, Wen, 21113 Chou, Chuan-Chu, 21053

Chu, Ed, 21438 Christiano, Angela M., 21113

Cbun, Sang-Yearn, 20855 Chung-Honet, Linda C.,

Cidlowski, John A., 20870 Clark, Ian D., 20897 Claussen, Traci J., 21454 Clemetson, Kenneth J.,

Clever, Jared, 20877 Closs, Ellen Ildicho, 20796 Coffey, Eleanor T., 21060 Cohen, Eric R., 20768 Coller, Barry S., 20741 Copeland, Neal G., 21035

C h i , Graham P., 20923 Corcoran, Marta L., 20725

Cousin, Jean-Louis, 20812 Cox, Jos A,, 20897 Crensbaw, Donna

CNZ, Miguel A., 21238

” I ~~~

20747

21113

20801

Greenwood, 21328,21335

AUTHOR INDEX

Cunningham, James M., 20796

Daiho, Takashi, 20930 Dailey, David, 21155 Davidson, Nicholas O., 20709 Davin, Laurence B., 21088 Dean, David A., 20877

de La Salle, Corinne, 20801 Dedhar, Shoukat, 20701

DeManno, Deborah A., 20729 de Paiva, Anton, 20838 Depka, Brigitte, 21246 D’Hondt, Kathleen, 20884 Dibirdik, Ilker, 21172 Di Pietro, Attilio, 20762,

Divita, Gilles, 20762 Dohrowolski, Steven F.,

Dolly, J. Oliver, 20838 Doniach, Sebastian, 20953

Durussel, Isabelle, 20897 Dosch, Jorg, 21102

Dynan, William S., 21225

Eherhardt, Thomas L., 21088 Edelman, Gerald M., 20683 Edelman, Marvin, 21246

Eliezer, David, 20953 Eldar, Hagit, 21097

Ema, Masatsugu, 21002 Enghild, Jan J., 21284 Erickson, Bruce W., 21193 Evans, Tony, 20983

Fambrough, Douglas M.,

Fan, Zhen, 21073 Fasolato, Cristina, 20737 Feng, Ping, 21453 Feng, Y., 21185 Fernandez-Pol, J. Albert,

Fertala, Andrzej, 21232 Fisher, Edward A., 21007

Flores-Rozas, Hernan, 21372 Fitz-Gibbon, Linda, 20701

Frank, Patrick, 20953

20911

21448

21185

21198

Franklin, Audrey A,, 21225

Freire, Ernesto, 20785 Fredericks, William J., 21271

Fritz, Gerhard, 21102 Fuhrer, Christian, 20772 Fujii-Kuriyama, Yoshiaki,

Furukawa, Takako, 21359 Funahasbi, Toru, 20709

Furuya, Shigeki, 21028 Gagne, Stephane M., 20897 Gawdi, Govind, 20791 Geffen, Iris, 20772

Giannoni, Federico, 20709 Gelpi, Emilio, 20958

Gilbert, Debra J., 21035 Gillis, Nanna, 20953

Glickman, Rhona L., 21425 Ginsherg, Mark H., 21080

Goethals, Marc, 20684 Gonzalez-Gronow, Mario,

Gorbea, Carlos M., 21035

Gosnell, Mark, 20917 Gordon, David F., 20818

Greenberg, Charles S., 21284 Greene, Lloyd A,, 21410 Greenspan, Daniel S., 21113 Griffin, Linda C., 20808 Griffiths, Gillian, 20772 Gross, Myron D., 20917 Gross, Richard W., 20713 Gudi, Tanima, 21344 Guillot, Dominique, 20911 Gupta, Chhitar M., 21344 Hamilton, Andrew D., 20695 Hamilton, Paul D., 21198 Hamilton, Susan L., 20974 Handin, Robert I., 21238

Harada, Nobuhiro, 21399 Hansson, Vidar, 21276

Hardy, Larry W., 21425 Harrington, Maureen A.,

Haugen, Bryan R., 20818 He, Lanfang, 21088

21002

20791

21271

Hehbachi, Ahdel-Malik,

Heiner, Annette, 21066 Hemker, H. Coenraad, 21130 Higgins, Joan A,, 20937 Hilkens, John, 21364 Hirabayashi, Yoshio, 21028

HoeMer, James P., 21225 Hodgson, Keith O., 20953

Hoffman, Guy G., 21113 Horak, Eva M., 20725 Horak, Ivan D., 20725 Hoth, Markus, 20737

Howe, Philip H., 21448 Howe, Louise R., 20717

Hsieh, Tao-shih, 21328,

Huang, Ru Chih C., 21351 Huggel, Katja, 20772 Hughes, Michael J., 20687 Huh, Ho Young, 20747 Hunzicker-Dunn, Mary,

20937

21335

Hunziker, Willi, 20917 Hurwitz, Jerard, 21372

20729

Iijima, Yasuteru, 21394 Indelicato, Stephen R., 21053 Inesi, Giuseppe, 21185 Iorio, Ronald M., 21425 Iriuchijima, Tokuji, 20863

Ishii, T., 21185 Ishibashi, Hiromi, 21212

Iwanaga, Sadaaki, 21384 Jahnsen, Tore, 21276 Jaiswal, Ani1 K., 21454 Jansen, Marcel A. K., 21246

Jault, Jean-Michel, 20762 Jarvis, Lisa, 21172

Jeevaratnam, Premala, 20701 Jenkins, Alison L., 21432 Jenkins, Nancy A,, 21035 Jesaitis, Algirdas J., 20983 Ji, Inhae, 20851 Ji, Tae H., 20851 Jiang, Weiping, 21035 Jiricny, Josef, 21218