SMARTFISH NuTRIFRIeNd 1100 is a juice based drink providing 200 Kcal per carton of 200 ml.NutriFriend 1100 contains low oxidised EPA & DHA, vitamin D3, fibre from pectin, and protein from whey protein isolate. A juice blend of pome­granate, apple, aronia and pear provides natural antioxidants in a synergistic composition for dietary management.

NutriFriend 1100 and Cancer Cachexia Smartfish NutriFriend 1100 is a FSMP (Food for Special Medical Purposes) and is approved for reimbursment for cancer cachexia and Scandi­navia. In cancer treatment, the nutritonal inter­vention plays important roles by providing strength and energy when the body really needs it, reducing weight loss. About 80% of all cancer patients are suffering from cachexia. Patients with cancer cachexia benefits from high dos­ages of omega 3 fatty acids EPA & DHA. The EPA & DHA fatty acids modulate mediators of catabolism in cachexia and induce weight gain.

The right nutritional intervention may also have positive effects on fighting cancer itself. The EPA & DHA fatty acids improves the functional­ity, structure and strength of the cells. The EPA & DHA fatty acids have in studies proven to slow cancer cell mistosi, exert anti­profilerative effects on cancer cells and work in synergy with chemotherapeutic drugs.

NutriFriend 1100 is suitable for persons with immune system failures, for improving the diets of patients unable to meet their nutritional requirements from foods, or persons experienc­ing unintended weight loss due to surgery.

NEW!NutriFriend 1100 Fresh Taste!

NutriFriend 1100NutriFriend 1100Medical Nutrition

• Omega­3 (EPA & DHA) has documented effects for cancer, and cancer cachexia *2,4,5,9

• Omega­3 (EPA & DHA) together with vitamin D3 and fibre from pectin has positive effects for cancer patients *1,2

• Omega­3 (EPA & DHA) is vital for functionality and structure of the cells

• Omega­3 (EPA & DHA) is important for optimal brain function and development

• Omega­3 (EPA & DHA) is essential fatty acids which the human body does not produce itself, and needs to be supplemented through diet

• Low oxidised EPA & DHA in liquid emulsion with proven high bioavailability *8

• Low oxidised EPA & DHA in liquid emulsion with convincing compliance data *8

1. Ref. An Increase in Reactive Oxygen Species by Dietary Fish Oil Coupled with the Attenuation of Antioxidant Defenses by Dietary Pectin Enhances Rat Colonocyte Apoptosis (The journal of Nutrition)Lisa M. Sanders,* Cara E. Henderson,* Mee Young Hong,* Rola Barhoumi, † Robert C. Burghardt,† Naisyin Wang,** Christine M. Spinka,** Raymond J. Carroll,* **Nancy D. Turner,* Robert S. Chapkin,* and Joanne R. Lupton*3* Faculty of Nutrition, † Department of Veterinary Anatomy and Public Health and ** Department of Statistics, Texas A&M University, College Station, TX 77843 J. Nutr. 134: 3233–3238, 2004

2. Ref. n­3 Fatty acids, cancer and cachexia, a systematic review on literature (British Journal of Nutrition 2007) Ramón Colomer, José M Moreno-Nogueira, Pedro P García-Luna, Pilar García-Peris, Abelardo García-De-Lorenzo, Antonio Zarazaga, Luis Quecedo, Juan Del Llano, Luis Usán, César Casimiro Volume: 97, Issue: 5, Pages: 823-831

3. Ref. Circulating 25­Hydroxyvitamin D Levels and Survival in Patients With Colorectal Cancer (Journal of Clinical Oncology) Vol 26, No 18 (June 20), 2008: pp. 2984-2991. Kimmie Ng, Jeffrey A. Meyerhardt, Kana Wu, Diane Feskanich, Bruce W. Hollis, Edward L. Giovannucci, Charles S. Fuchs. From the Division of Medical Oncology, Dana-Farber Cancer Institute; Departments of Nutrition and

Epidemiology, Harvard School of Public Health; Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital, and Harvard Medical School, Boston, MA; and Division of Pediatrics, Medical University of South Carolina, Charleston, SC

4. Ref. Supplementation With Fish Oil Increases First­Line Chemotherapy Efficacy in PatientsWith Advanced Nonsmall Cell Lung Cancer(American Cancer Society)Rachel A. Murphy, BSc1; Marina Mourtzakis, PhD2; Quincy S. C. Chu, MD3; Vickie E. Baracos, PhD3;Tony Reiman, MD, SM4; and Vera C. Mazurak, PhD1(Cancer 2011;000:000–000.VC 2011

5. Ref. Oral Nutritional Supplements Containing (n­3) Polyunsaturated Fatty Acids Affect theNutritional Status of Patients with Stage III Non­Small Cell Lung Cancer during Multi modality Treatment1–3 (The Journal of Nutrition and Disease)Barbara S. van der Meij, Jacqueline A. E. Langius, Egbert F. Smit, Marieke D. Spreeuwenberg, B. Mary E. von Blomberg, Annemieke C. Heijboer, Marinus A. Paul, and Paul A. M. van Leeuwen, Department of Nutrition and Dietetics, Internal Medicine, Department of Pulmonary Diseases, Department of Epidemiology and Biostatistics, and Department of Pathology, Department of Clinical Chemistry, and Department of Surgery, VU University Medical Center, Amsterdam, The Netherlands

6. Ref. Effect of Smartfish and other commercial marine oil products on lipid peroxidation in U937 cells (University of Oslo, Department of Nutrition) 24.03.09 Dr. Harald Carlsen, Dr. Fred Haugen

7. Ref. Low oxidized oils and potential health advantages (NOFIMA On request)Bente Ruyter, Gjermund Vogt, Stine Grimmer, Trine Thorkildsen and Marijana Todorcevic

8. Effects of a convenience drink fortified with n­3 fatty acids on the n­3 index (British Journal of Nutrition, Published online ahead of print, doi: 10.1017/S0007114510001054)Authors: A. Kohler, D. Bittner, A. Low, C. von Schacky

9. Omega­3 fatty acids in cancer, the protectors of good and the killers of evil?Department of Women’s and Children’s Health, Karolinska Institutet, S-171 76, Stockholm, SwedenHelena Gleissman, John Inge Johnsen, Per Kogner, Childhood Cancer Research Unit

10. Acute inflammation: signals in resolutionBruce D. Levy, Clary B. Clish, Birgitta Schmidt, Karsten Gronert and Charles N. Serhan 2001 Nature Publishing Group http://immunol.nature.com