Now What Do I Tell Her? All The Things to Do to Use Donor Egg Maria M Jackson MA, RN.
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Transcript of Now What Do I Tell Her? All The Things to Do to Use Donor Egg Maria M Jackson MA, RN.
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Now What Do I Tell Her?All The Things to Do to Use Donor Egg
Maria M Jackson MA, RN
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Learning Objectives
Understand the emotional impact of infertility and the transition to using donor gametes
Discuss potential gender differences and societal influences on each partner
Identify concerns and obstacles that impede the transition
Explore strategies to help patients become more comfortable with this reproductive option
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What is the nurse’s role in the donor egg process?
Role of the nurse in DE is multi-faceted Liaison Educator Sounding board Coordinator Counselor
~50% of SART member clinics have MHP on staff Grief counseling integral part of role
Failed cycles Miscarriages
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Steps in the Process
Acknowledge their emotions Normalize their feelings Identify their concerns/ obstacles Give them resources Give them time
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Case Study
Dr. Jones comes to your door with Mr. & Mrs. Smith in tow. They have done 3 IVF cycles and have been unsuccessful. Today’s consultation was to discuss next steps.
She is visibly upset and trying unsuccessfully to keep her emotions in check. He is looking at his watch and appears to be in a hurry to leave. Dr. Jones tells the couple he’s going to put them in your capable hands and you’re going to tell them everything they need to know about using donor eggs.
He has already given them a brief overview of the process anddiscussed other options including adoption and living childfree.
So how do you begin the conversation???
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How do you begin the conversation?
“Mary, I see you’re upset. This process is difficult and challenging. It can feel like an emotional punch in the gut…”Raw emotions can be uncomfortable to witness
Crying is an appropriate response
Using donor eggs is not a cure for her infertility
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Acknowledge the emotions
“Mary, I see you’re upset…” A diagnosis of infertility has been likened to Kubler-Ross’ stages of death and dying because it involves multiple losses on multiple levels
The emotional response to loss is mourning and grieving
Couples may not recognize it as such They may need permission to jump off the
treatment treadmill for a while and just experience the emotions
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Unlike traditional mourning and grieving the child was never born…so how do you mourn and
grieve a dream?
Dream Reality
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Case Study Continued…
The couple is seated in your office. Mary, an attorney is crying and her husband John, a bond trader is busy texting. She and John have been married for about 10 years.
Mary got pregnant in law school before meeting John and terminated the pregnancy. They decided as a couple to delay childbearing until they were established in their careers despite pressure from their parents to give them a grandchild.
Mary admits she never expected to be infertile; she has planned her life out with great care and was shocked when she didn’t conceive. She shares that the IVF process is having a negative impact on all aspects of her life and now Dr. Jones is recommending egg donation. She’s just not sure she can use someone else’s eggs.
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Acknowledge the emotions
Common emotional responses to infertility Depression Anger Guilt Confusion Loss of control Questioning the meaning of your relationship Failure
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Normalize Their Feelings
It’s normal to have fears, concerns, doubts when using a third party to conceive
This is a nontraditional form of family building No one expects to give over control of their
reproduction to strangers It may take some time to get comfortable with
the idea of using another person’s eggs Using donor eggs is not a cure for infertility
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Lot’s of folks are using the donor egg option
SART Clinic Summary Report 2012Donor Oocytes (all ages)
Fresh Embryos Thawed Embryos
Transfers 9250 7608LBR/ET 56.6 37.2Avg # embryos/ET 1.8 1.8
https://www.sartcorsonline.com
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Gender differences
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Case Study Continued…
John has finally put down his phone at Mary’s urging. He reminds her this process is expensive so his job is important. Mary asks him how he feels about using donor eggs and he replies,
“I’m willing to do whatever it takes to have a child. We can choose the donor and you carry the pregnancy. It’s not what I expected but it seems like the best option. We’ll have a much better chance of conceiving.”
Mary continues to cry and tells John she feels as if she’s let him down that this is all her fault. He reminds her his sperm count wasn’t the best so he share’s some of the responsibility.
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Gender Differences
Mary Role failure
Pregnancy is played out in a woman’s body Impacts self-image
Women practice playing Mommy from childhood
Experience more stress May need to talk (too much) about
infertility to cope with the diagnosis Social support is important
Peterson et al Hum Reprod 2006; 21: 2443-2449
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Gender Differences
John Distancing more often used by men to cope
Not comfortable exposing themselves emotionally
May work longer hours May consume more alcohol
Self-control and problem solving typical He wants to fix this for his partner
His coping style does not mean he’s less invested
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Identify Obstacles
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Common Obstacles
Unresolved issues surrounding the couple’s infertility
Societal attitudes Religious restrictions Age
Fears about the donor Honesty Reliability Can I see a picture?
Concept of multiple parents Concerns about bonding with the baby Is it going to work????
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Unresolved issues surrounding the couple’s infertility Grief work is an integral part of the process
Many losses Closeness as a couple Confidence in their ability to accomplish an
important life task Both must mourn the loss of the woman’s
genetic contribution Unsure how to help each other cope with the
complex personal & medical issues Unexpressed anger, fears or concerns about
using donor gametesMahlstedt & Greenfeld Fertil Steril 1989; 52: 908-914
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Strategies
Mandatory pyscho-educational meeting with MHP before they can cycle They don’t know what they don’t know
In person or online support groups Resolve: http://www.resolve.org/support-
and-services/ The American Fertility Association: http://www.theafa.org/advice-support/
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Societal Attitudes
“Her horrifying personal story about using a host of assisted reproductive technologies (ART), including in vitro fertilization (IVF) and egg donation, in an effort to have a child is part memoir and part exposé of an unscrupulous, high-profit industry. It’s a compelling read.”Book describes a 6 year struggle with infertility that ended with the couple adopting
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Societal Attitudes
“Blood is thicker than water”Does society favor biological ties?
“At least one of us will be biologically connected”Are we as a society ambivalent about non-traditional family building?
Will the grandparents love this child the same? Will this child be accepted or treated differently?
My religion doesn’t condone the use of donor gametes under any circumstances
If God wanted me to be pregnant it would have happened
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Strategies
In 2014 families are created in many ways We assume a biological and genetic connection
that may not be present A grandparent’s ability to love their grandchild is
not dependent on a biological connection Fear of parent’s rejection may be related to life-
long issues (rejection/criticism) rather than the child’s means of conception
Religious sanction for ART may never happen If God didn’t want people to have children these
technologies would never have been developed
Mahlstedt & Greenfeld Fertil Steril 1989; 52: 908-914
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Is She Too Old For This?
“Old parents face a version of the judgment implicit here: They have no idea what they’re in for. More than that: This is just not right. A new child may be a blessed event, but when a 50-year-old decides to strap on the Baby Björn, that choice is seen as selfish and overwhelmingly prompts something like a moral gag reflex. “
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How old is too old?
Concerns for the mother’s health Careful screening required Adequate counseling re: risks of
complications SET strongly recommended Discouraged/denied in women 50 and
over with underlying medical conditions & >55 regardless of health
ASRM Ethics Committee Report: Oocyte or embryo donation to women of advanced age Fertil Steril 2013; 100: 337-340.
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How old is too old?
Ethical concerns for the donor conceived offspring Possibility that one or both parents could
die before the child reaches adulthood Stresses of parenting as an older parent Difficulties of meeting the emotional and
physical demands of parenting
ASRM Ethics Committee Report: Oocyte or embryo donation to women of advanced age Fertil Steril 2013; 100: 337-340.
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Strategies
Ageism still an acceptable bias in 2014 Hypocritical given how many US grandparents
are primary care givers to young children today 3 mil (2011) Pew Research Center
Older parents often have more resources Age alone does not make one a good parent
Less parental stress reported by older moms ART children outperformed peers on
standardized test scores in a comparison study Older the mom the better the better they did
http://www.pewsocialtrends.org/2013/09/04/at-grandmothers-house-we-stay/Van Voorhis et al Hum Reprod 2010; 25: 2605. Paulson Fertil Steril 2007; 87: 1327- 1332
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Fears about the donor
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Fears about the donors
Who are they? Why do they do it? What are the
options? How are they
screened? What
characteristics should I consider?
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Donors: Who are they?
21-31/32yo Motivation is a combination of altruism
and financial compensation Compensation amounts vary regionally They often know someone who’s
experienced infertility and want to help
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Donors: Source options
Clinic recruited (Fresh) Couple is screened and matched by the
clinic staff Agency recruited (Fresh)
Couple selects donor to be screened Egg bank
Screened and stimulated
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Source options: Clinic recruited
Advantages: Passed screening Donor is known to staff
Disadvantages: Couple is matched to the donor Identity release option not available May or may not see photos
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Source options: Agency recruited Advantages:
Couple selects donor Can see photos May choose identity release
Disadvantages: May not pass screening process
Emotional let down Compensation may be higher Travel expenses additional cost
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Source options: Egg Banks
Advantages: Convenient Affordable Timing is not an issue PR are comparable
Disadvantages: Fewer frozen embryos Inventory ebbs and flows Some still consider this experimental
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Source options: Egg Banks
In 2013 ASRM Practice Committee published a paper entitled, Mature oocyte cryopreservation: a guideline Removed the “experimental” status
Impacted insurance coverage Made egg banks more accessible to
patients in states with mandated coverage for infertility
Fertil Steril 2013; 99: 37-43
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Donors: How are they screened? ASRM Guidelines
FDA Genetic Ovarian Reserve General health Psychological
Fertil Steril 2013; 99: 47-62.
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Donors: How are they screened? Psychological screening is as important
as physical screening MMPI/PAI Clinical interview
Ovarian reserve screening may be of particular importance to young recipients
Discuss the significance of blood type
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Donors: Can I see a picture?
Policy varies from clinic to clinic Adult/childhood/
both Egg banks policies
may also vary Some recipients
find a picture comforting others a reminder of the donor
“She has to be young and pretty just like me”
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Strategies
Reassure them: Donors are nice people In person forums very helpful
Give them a list of all the testing done Provide a genetics report Emphasize the thoroughness of the psych
evaluation Info re: ovarian reserve testing Significance of multiple measures D3, AFC,
AMH Discuss the significance of blood type
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Concept of Multiple Parents
Whether the couple discloses the use of donor eggs to the outside world or not they know there is a third person involved
Genetic and biological relatedness not required to create a family
Framing the use of donor gametes in the context of society as a whole may be helpful Divorce Adoption
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Concept of family is changing
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Concept of Multiple Parents
Donor presence recedes over time but never really goes away
Focus changes over time from donor and recipient to the offspring Offspring are often the forgotten ones
Who is the real mother?
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Strategies
There is one mother Introduce the concept of mDNA Empowering and restores a sense of control
Anonymity infers no identity Donor is real and will always be a part of
their lives She can be a helper or a threat
Prepare them for resemblance talk Innocent remarks can be a painful reminder
of the donor’s presence
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Concerns About Bonding
http://www.nurture.co.za/wp-content/uploads/post-secret.jpg
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Concerns About Bonding
“I fell in love with my son the moment I saw him for the first time on the ultrasound. I will never forget how it felt to see his tiny heartbeat flashing on the screen before we could even hear it.”
“I know that he is not genetically related to me. But he still is, and always will be, MY SON. I'm the one he snuggles next to when he's hungry and wants to nurse. I'm the one he cries for when he wakes up in the middle of the night and can't sleep. I'm the one he crawls to with a big smile on his face when I come home after a long day at work. He is MY SON and I am HIS MOTHER. I love him so much it makes my heart ache. I have never felt disconnected from him and I don't ever really think about the fact that we don't share DNA. “
http://anonymousus.org/stories
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Concerns About Bonding
“I am pregnant with a donor baby and basically have butterflies in my stomach the whole time time. I don't feel like I am bonding with it al all. I wish it would miscarry and go away because it just doesn't feel right. The clinics don't go through this do they when they take your payment of $8,000 None of this is discussed. The whole thing just feels wrong to me. I did this for my husband. He so wants to be a dad. People do have a right to know where they come from. It's a natural human instinct to want to know. But it's also a natural human instinct to want to pass on your jeans and have children. But if this cannot happen for couples, then that should be it. IVF fine, but using other people's eggs and sperm is wrong and a step too far. I feel what we have done is wrong. My husband has no idea how I feel. I feel very alone and isolated with no to talk to. Everyone expects me to be happy but I am putting on a brave face. I have been off work for weeks with terrible morning sickness and just want this baby to go away so that we can live a clean life.”
http://anonymousus.org/stories
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Strategies
Concerns are real and appropriate It is normal to have concerns Not everyone will embrace the DE option and
we shouldn’t talk them into it 23 chromosomes exert a lot of influence
Child will never have Dad’s ____ or Mom’s ____ Maternal DNA is also being passed to the
child during pregnancy Responsible for far reaching epigenetic
modifications
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Is It Going to Work?
Investment of time money and emotions are worth it if…
Some are not prepared for negative outcomes no matter how much they’re counseled 40%-60% of embryos are euploid
Realistic expectations SART data 56.5% THBR
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Strategies
Manage their expectations Give them SART Summary Report for your clinic Discuss inherent loss rate in pregnancy
regardless of age Review normal reproductive physiology and
rate of attrition from follicle eggembryobaby
Be honest there is a leap of faith required Increasing number of IRMS patients
choosing aCGH to maximize their chancesPatrizio P, Sakkas D. Fertil Steril 2009; 91:1061-1066.
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Resources: Bibliography
Give them all the information they need to make an educated decision MHPG Bibliography
http://www.asrm.org/uploadedFiles/ASRM_Content/About_Us/Specialty_Societies/Professional_Groups/MHPG/MHPG_Childrens_Bibliography.pdf
Translated into many languages http://booksfordonoroffspring.blogspot.ca/
Selective reduction
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Resources: Donor Selection
Health and family health hx most important
Blood type: disclosure decision impacts donor choice
Education often confused with intelligence
Open identity option? Influence of staff on donor choice
They trust you and your opinion matters
Braverman et al Fertil Steril 2011; 96: S10; Braverman et al Fertil Steril 2010; 94: S67.
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Resources: Disclosure
Parents may be conflicted Fear the child will want to find the donor
Some make legitimate reasons for non-disclosure
Fear stigmatization if DE goes against cultural norms
Timing is important Research comparing DE, DI to adopted
and naturally conceived positiveGolombok et al Hum Reprod 2002; 17: 830-840
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Case Study
Mary and John have opted to use a fresh donor from our program. They had looked at multiple profiles and asked for input from the DE team re: the best donor. They are not sure if they are going to disclose the use of donor egg to their children. It has taken Mary a few months to get comfortable with the idea of using donor eggs. She asked if she could talk with another recipient who has already cycled and seemed more at peace after doing so.
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Give Them Time
Reproducing with someone else’s eggs is not the same as using one’s own
Waiting list can offer the gift of time when the couple is on the treatment treadmill and can’t get off
This is a process that requires assimilating a lot of information
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Final Thoughts
Be aware of your personal feelings re: third party reproduction
Your opinions matter We communicate both verbally and non-
verbally and may be influencing patients My personal philosophy is to be as
unbiased as possible Give them the resources and let them
make the decision
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Summary
DE is not a cure for infertility Patients often have many concerns and
obstacles transitioning to DE The nurse’s role is multi-dimensional and
significant There are many resources available to
patients to help them make informed choices
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IRMS at St. Barnabas