November 10, 1970, NIH Record, Vol. XXII, No. 23
Transcript of November 10, 1970, NIH Record, Vol. XXII, No. 23
U. 5. DEPARTMENT OF
H EALTH. EDUCATION. AND WELFARE
Dr. Eldon Eagles Named To Newly Created Post, NINOS Deputy Director
Dr. Eldon L . Eagles has been named deputy direetor of the National Institute of Neurological Diseases and Stroke.
In this new position, Dr. Eagles will share responsibility for the ln~tute's programs and activities with Dr. Edward F. MacNicbol, NINDS Director.
For the past 6 years D'l·. Eagles has se'l·ved as assistant director of NINDS. Since 1968 he has concurrently served as acting associa'U! direc,tor for 0ollaborative and F ield Resem-ch for the Ins,titute.
Prior to joining NINDS, Dr. Eagles was associate research pl"Ofessor of Maternal and Child Health and the University of Pittsbul·gh Gr,-uiua.te Sch-001 of Public Health.
While at the Univeirsity, Dr. Eagles serves on various PHS research and training advisory committees.
Dr. Eagles holds an M.D. and a Master of Surgery from Dalhousie University, Halifax, Nova Scotia, a Di,ploma in Public Health from the University of Toronto, and a Doctorate in Public Health from The J ohns Hopkins Univers,ity.
He pi·acticed general medicine
Dr. Eagles' study of hea ring in ove r 5,000 Pittsburgh school children during the early sixties led to improved hearing tests.
foo· 3 years in a rui-al area of Canada and served a,s a medical health officer in Nova Scotia for 15 years.
He directed a child and maternal health program the1-e from 1954 to 1956.
ecor November 10, l 970 Vol. X.XII, No. 23
Dr. Frank (r) and some of his staff use II new computer system for determining which a spects of a monkey's response can be predicted from ncuroelectric signals recorded from the motor cortex. Laboratory membe rs (I to r) are: Paul Yarows ky, Kathleen Davis, Dr. R. Gilbert J ost , Dr. Donald R. Humphrey, and Dr. Edward Schmidt.
Ily Carolyn Holst ein
You stumble on a step and "instinc!Jh-ely" grab hold of the rail-you've stopped yourself from falling without much eff<>rt. But imagine doing <the same thing with an artificial hand.
Although artificial hands can look fairly normal, they cannot as yet to unders.tand and therefore to perform very complex tasks O'!'
functions because they are not uirectly controlled by the body's nervous system.
To integrate them w:ith the nervous system requires more understanding of how the system works.
Th,is has commanded the attent ion of experts for years, for th':\ nervous system's oomplexity, which makes it so wonderful , ah;o makes it one of the mos,t difficult systems
A year later Dr. Eagles was a resoarch fellow at the Johns Hopkins University School of Hygiene and Public Health and at the same time was Director of Studies for the Maryland State Planning Commission Committee on :Medical Care.
During this J)e1·iod he conducted a study of medicaJ services and faoilitJies needed by handicapped children in Maryland which resulted in 10gislative action and the appropriation of f unds.
Dr. Eagles, who has published s.ome 30 papers and monographs, is a fellow of several professional societies.
mimic. Being able to mimic the system
would not only enable scientists to develop better-more responsiv-.ai·tificial limbs for amputees, but also help them to perfect sensory prostheses Ioi· blind and deaf persons, according to Dr. Karl Frank, chief of the NINDS Laboratory of Neural Control.
Such devices, already under development, may eventually help blind persons to navigate in their surroundings or decipher letters and even words.
These devices could work by projecting tactile images onto the skb of blind pcTSons, producing a sensation similar to that felt when someone writes with bis finger on yonr back, or they might work by delivering patterns of electrical stimuli directly to bhe brain.
Mimicking the system could also enable scientists to extend the capabilities of normally working limbs, by having information recorded from the brain bypass muscles and instead directly activate and control
(Ser NSRVOUS SYSTEM, Page 7)
NATIONAL INSTITUTES OF HEA LTH
Dr. Berliner to Receive Research Achievement Award of Heart Ass' n
Or. Robe1-t W. Berliner, NIH Deputy Di.root:or for Science, has been seleded to receive the American Heart Association's 1970 Research Achievement Award.
The award is being pre.sented for his "many contributions to ca.rtliovascular research-particulllrly renal physiology- as investigator, as a teacher and trainer of young scierutists, and as an administrator."
Receives Award Thursday
Dr. Berliner will receive an honorarium of $1,000 and an illumi-· nated scroll at ceremonies opening tlhe Association's annual scientifi.c sessions this Thm-sday (Nov. 12) in Atlantic City.
Dr. W. Procto,r Harvey, AHA President, vnll pre.sent the award.
Dr. Berliner's interest in cardiovascular phenomena wa;s evident early in his career by a. study showing that changes in human posture could res.ult in changes in blood circulation, producing a form of la.bored breathing often associated with congestive heart failure.
In 1946, he reported a simple clinical procedure for measuring the rate at which blood flows through and is filtered by the kidney, and his investigations showed the effect of mercury preparations in increasing uhe secretion of urme.
Dr. Berliner made another major contribution in 1948 when he demonstrated the secretion of potassium by the kidney.
He has done extensive srt;udies on
(See DR. "Bl::Rl,JNER. Pa.ye j)
TV Presentation on Viruses To Feature NIAID Story
"You and the Virus" may be seen on Channel 4 (WRC-TV) this Saturday, Nov. 14, at 1 :30 p.m.
The HEW-sponso1·ed television show will present the NIAlD st o1·y of virus.es and how they affect mankind.
Fealured ,vill l:>e Drs. Daniel Mullally, Wallace Rowe, Samuel Baron, and Julius Kasel; also, Edward Harvey, Margaret Huber, and Holly Smith.
Page 2 November 10, 1970 THE NIH RECORD
Published biweekly at Bethesda, Md., by the Publicat ions and Reports Branch, Office of Information, for the information of employees of the National Institutes of Health, Department of Health, Education, and Welfare, and circulated by request to interested writers and to investigators in the field of biomedical and related research. The content is reprintable without permission. Pictures are available on request. The NIH Record reserves the right to make corrections, changes or deletions in submitted copy in conformity with the policies of the paper and the Department of Health, Education, and Welfare. NIH R9'ord Offi,o .... ................... , Bldg, 31, Rm, 28-03, Phone: 49-62125 Editor ... .................................................. ...... .. ..... ...... ......... Frances W. Davis
Stoff Correspondents ADA, Nelson S.parks; BHME/ OD, Florence Foelak; CC, Elsie Fahrenthold; DAHM, Laura Mae Kress; DBS, Faye Peterson; DCRT, Joan Chase; DDH, Carolyn Niblett; DGC, J ames McLaughlin; DMI, Florence Foelak; DN, Evelyn Lazzari; DPHPE, Eleanor Wesolowski; DRG, Marian Oakleaf; DRR, Dave Dunlap; DRS, Robert Knickerbocker; FIC, Jan Logan; N CI, Pat Gorman; NEI, Julian Morris; NHLI, Bill Sanders; NIAID, Krin Larson; NIAMD, Katie Broberg; NICHD, Lloyd Blevins; NIDR, Sue Hannon; NIEHS, Elizabeth Y. James; NIGMS, Wanda Warddell; NIMH, Daniel Rice; NINDS, Anne Tisiker; NLM, Peter Monk.
Employees May Consult Counselors on Enrollment In Federal City College
'I'wo counselors from Washington's Federal City College will be at NIH Nov. 17 and 18 to advise employees about educational opportunities at the college.
The counselors, Carol Spencer and Yvonne Coursey, will be available for half-hour appo~ntments in Bldg. 31, and if there are sufficient requests, appointments may also be scheduled Nov. 19 and 20.
An appointment may be made by calling Training a.nd Employee Development, Ext. 62146.
Students may enroll in the Federal City College for bachelor or graduate degrees or <in the nondegree progziaro. Both day a.nd evening courses are given.
The basic requirement for enrollment is a high school diiploma or the equivalent.
The e-0llege is the first Urban Land Grant institution in the country. Because it receives Federal funds, its tuition charges are low.
Tuition oosts are $25 per fulltime qua.r>ter for D.C. residents and $240 for non-oresidents. Part-time tuition cost is determined by the number of credit hou:rs.
NIH Television, Radio Program Schedule
Television NIH REPORTS
WRC, Channel 4 1 a.m. Wednesday
November 11 Dr. Frank W. Hastings, chief,
Artificial Heart Program, NHL!
Subject: Artifioial Hearl Program, Pa.rt 2 (R)
November 18 Part 3 of the above program
(R) Radio
DISCUSSION: NIH WGMS, AM-570-FM Stereo 103.5-Friday, about 9:15 p.m.
November 13 Dr. Henry M. Fales, NHL! and
Alan Demmerle, DCRT Subject: Automation in the
NIH Laboratory
November 20 Dr. Carl Kupfer, Direot1•!", NEJ Subject: The Role of NEI in
Combating Vision Disorders Interview takes place during in
termission of the Library of Congress concerts.
NIH Ski Club Plans Holiday Trips to Several Areas The NI H Ski Club will start
its winter season early this year with a 4-day Skifest in the Laurentian Mountain Resort of Sun Valley, Province of Quebec, from Nov. 25 to Nov. 28.
Members are also participating in a 2-weck ski holiday to Kitzbuhel in Innsbruck, Austria over the Christmas holidays.
Other trips are being planned for New England and the deep powder
area of the Rocky Mountains. Seve.ra.l weekend trips will be scheduled for Blue Knob and Seven Springs areas in Pennsylvania, too.
A meeting will be held at noon, Nov. 18, in Wilson Hall (Bldg. 1) to discuss these events. Also featured will be a ski fashion show and equipment demonstration.
Anyone interested in the club activities may contaot the R& W Association Office, Ext. 66061.
Blood Bank at CC Initiates New System; No Changes in Benefits to Employees
The Clinical Center Blood Bank is now operating the NIH blood donor program-with its blood credit system--on an independent basis.
The new progran1 became effective on Oct. 15. Under the old system, the Blood Bank had a contract with the
American Red Cross, ·and blood donated at the Clinical ,Center was credited to the Washington Regional Red Cross Blood Program. Now it is credited to NIH employees.
Nothing changes as far as benefits to employees are concerned. Donors can still give blood at the CC Blood Bank and earn blood coverage for all employees and their families.
Alternate Pion Continues
The alternate free pint which is donated is needed to earn this cover-age. Donors oontinue to be paid for every other pint.
Employees may have 4 houn; administrative leave-at the discretion o.f the supervisor-at the time of donatiing. All dooations are reoorded, on an NIH card now instead of a Red Cross ca.rd.
"The new blood credit system is really much more efficient,'' Dr. Thomas C. Chalmers, OC Di.rector, explained, "since we can respond to all the blood needs of employees directly instead of through a middleman."
Schmidts Donate One of the last NIH employees to
give under the old Red Cross system was Dr. Paul Schmidt, Blood Bank chief; one of the first dono:r6 under the new NIH system was his wife.
Both are Rh negative, but Mrs. Schmidt says, "I have given more blood than he has, and mine is better."
Both of them sbarted donating at the age of 18. Dr. Schmidt admits, "This was a few years ago."
He remembers the dalte of his
Film Encourages Employees To Plan Secure Retirement
A film on retirement entitled, "The Root of Your Life," is being presented next week by the Employee Health Service.
The 28-minube color movie tells the story of how retirement plans were introduced to industrial workers and their amusing reactions.
The film is being shown to encourage employees to begin planning now for the time when they can terminate their careers and enjoy life with a feeling of security.
The EHS movie will be shown at the Jack Masur Auditorium, CC, on Wednesday, Nov. 18, at 11:30 a .m. and 12:15 p.m.; at Conference Room A, Westwood Building, Thursday, Nov. 19, at 1:15 and 2 p.m.
When o fellow needs o blood tronsfu . sion, your donation moy be the one that con pull him through the crisis.
first vis-it to a Red Gross Blood Center because it was the day he was acc~pted by the U.S. Army.
He also admits that he is proud of Mrs. Schmidt, who has supplied many O Rh negative pints of blood for NIH patients in emergencies.
The CC Blood Bank has developed many techniques and establis!hed itself as a leader in modern bloodbanking.
Components Serve Needs For example, by using blood com
ponents (splitting fresh blood into many parts) one pint provides therapy for several patients. Each component serves a specific need for ea.ch patient, and no potibion is wa.sted.
Installation of a pioneer computer system has proved to be a step forward also. This Donor File and Recall system has enabled the Blood Bank staff to record and quickly retrieve valuable information about individual donors.
Comme rcial Sources Eliminated Elimin,ation of the commercial
blood bank source for NIH supplies is another imporlant recent improvement. The result of this action, which was based on research conducted by the Blood Bank staff, has been a greatly decreased ineidence of transfusion-xelated hepatitis in the Clinical Center.
A ca.JI to the CC Blood Bank, Ext. 64509, will give:
• :More in.formation about the new blood credit system,
• The Red Cross Blood Center schedule for those who wish -to keep a personal affiliatlion with the o,rgll.ni,1abion 's program,
• An appointment to deposit blood in the OC Blood Bank.
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THE NIH RECORD
Three Training Programs Offer Eligible Candidates Chance to Aid Careers
NIH is seeking candidates for long-term traiTili1g opportunities under the Career Education Awards, the Systematic Ana.lysis, and the Mid-Career Programs by Nov. 16.
The first two programs are sponsored by the National Institute of Public Affairs; the Mid-Career Program, sponsored by Princeton University.
Plans Assist Executives
All three plans assist Federal and stiate executives in developing those employees identified as competent to assume high-level positions and provide specific edU(:ation that agencies are usually not able to offer.
Eight universities participate in the Career Education A wards Program: Cornell, Harvard, I ndiana, Princeton, Stanford, and Universities of Southern California, Virginia, and Washington.
Six major universities take part in the Systematic Analysis Program: Universibies of California, Maryland, and Michigan, Massachusetts Im,-titute of Technology, Harvard, and Stanford.
Assignment of selected nominees to universities is the responsibility of the U.S. Civil Service Commission; howevro.·, when possible, preferences will be followed.
Select Own Program
Each participant is allowed to select a study program tailored to his specific needs. He will be able to attend special seminars and participate in other educational activihies.
The eligibility requirements for the three programs vary. Generally, applicants should have been Nl H employees for at least 2 yoors, and have an undergraduate achievement of at least a "B" ave.rage.
The eligibility grade varies. For the Career Educa,tion Awards, GS 11 through GS 15 or equivalent ; for the Educational Program in Systems Analysis, GS 9 througih GS 13 or equivaJent. Applicants for the Mid-Career Program at Princeton should be in grade GS 14 or above.
Age Requirements Give n
Ge=al age requirements are: between 28 and 35 years for the Career Education Awards Program; between 25 and 30 years for the Systematic Analysis Proi,'Tam, and in the thirties or forties for the Mid-Career Pro.gram.
Applications must be received by the Office of the Assistant Dfrector for '!'raining and Employee Development, Office of PerS-Onnel Management, no later than Nov. 16.
Further details may be obta:ined from the Training Office.
November 10, 1970 Page 3
Progress Report of CFC Shows NIH Has Reached 87.6 Percent of Goal
Drs. Hartley, Huebner Share 1970 Kimble Award
Three more groups have exceeded their Combined Federal Campaign quotas b1·inging NIH to 87.6 percent of i~ goal.
Their percentages are: BHME, 119.5; NLM, 107.5, and the Fogarty International Center, 128.7.
The Oct. 28 progress report shows total NIH contributions of $191,485.81 with 77.1 percent partieipatfon.
'l\vo organizations, BHME and NIGMS, have re.adhed t heir goals with 100 percent or more participetion.
"We are deeply groteful to all who have responded so generously thus far in the campaign," said Dr. Carl G. Bake•r, Director of NCI and CFC Chairman.
After ,the official close of the campaign, contributors may send donations directly to the Combined Federal Campaign Headquarters, Nassif Building, Room 3411, 400 7th Street, S.W., Wru,hington, D.C. 20546.
CC Patients'
Two cancer research scientists from NIH-Dr. Janet W. Hartley and Dr. Robert J . Huebner-shared the 1970 Kimble Methodology Award.
The co-winners were ci-ted for their work in significantly advancing methodolgy and knowledge in virology and oncology.
Dr. Hartley is in the Labo1-artory of Viral Diseases, Naliional Institute of Allergy and Infectious Diseases; Dr. Huebner is chief of the Viral Carcinogenesis Branch, National Cancer Institute.
The Kimble Awa.rd, a $1,000 cash prize and engraved plaque, is made annually by the Conference of Public Health Laboratory Directors of the American Public Health Association.
The award, sponsored by Owenslllinois, Inc. was presented at the annual APHA meeting Oct. 26 in Houston, Tex.
Methods developed by Dr. Hartley have improved studies of human and animal viruses and provided tools for the detection and charac-
Winne rs in the CC Patients' Annual Hobby and Occupational Therapy Shaw received Achieveme nt Trophies for the items judged best. Some 65 patients displayed their arts a nd crofts, made during their stay here, in the CC lobby: Theresa Gorton (top left), St Louis, Mo., won first place in "The Most Original" category with a dry flowe r arrangement; Frances J. Habiak (top right), Sayerville, H.J . received an award tar he r knitted poncha in the "Most Likely to Be Purchased" category. Leonard E. Spires, Riverside, Calif., wan "Best in Show" for his fra med appliquc of golden eagles.
Or. Huebner (I) and Or. Hartley discuss virus research for which they received the 1970 Kimble Methodology Award .
teriz.ation of the naturally-occur ring C type leukemia viruses in mice.
This latter work has led to new corn:epts and methodological approaches to the study of human cancer.
Some of Dr. Hartley's vfrus test systems now in use include adenovi:ruses, cytomegaloviruses, mouse polyoma viruses, and mouse hepat itis viruses.
She als,o developed a method for standardization of the oomplcment fixation test for murine leukemia viruses and in vilffo isolation, a ssay, and rescue systems th.alt are now being adapted to study human cancer.
Wark De scribed
Dr. Huebner's work has centered on the detection of antigen associated ,vith tumors produced by viral agents.
With his associates he has demonstrated the occurrence of virusspecifie, complement-fixing antigens in tumors induced by the adenoviruses, Rous sarcoma vb:us, SV-40, and animal leukemia viTuses.
One practical application of his findings would permit a searoh for viral "fingerprints" in human tissues and thus help to answer the question of th.e causal role and identnty of viruses in human cancer.
Dr. Davies Directs Lab Under Rotating System
Dr. David R. Davies has been appointed acting chief of the LaboratoL·y of Molecular Biology, National Institute of Arthritis and Metabolic Diseases.
He will serve for one y,ear, replacing Dr . Gary Felsenfeld, who headed the laboratory from November 1969.
A system of rotating th.e position of chief of the laboratory is now in its second yea.i-. It is believed to be tJhe first such system to be used at NIH.
L. Lee Monue l hos bee n oppointed Executive Office r of the Division of Computer Research and Technology, which he joined in 1966. For 5 years, he was Administrotive Officer far the NCI intramura l programs.
3 Members Named to Nat'I Advisory Council On Health Professions
Three members have accepted app ointment to bhe National Advisory Council on Health P1'ofessions Educational Assistance: Drs. :Maurice J. Hickey, Mabelle G. McCullou gh, and David W. Talmage.
Dr. Hickey has been Dean of the School of Dentistry, University of Washington, sance 1956. From 1948 to 1956 he served as Associate Dean of the Faculty of Medicine and Execut ive Officer, De.partrnent of Denm.stry, Columbia University.
Dr. McCullough is Assistant Dean of Students, University of Milrnesota, and has been associated with the University since 1945.
She has served as a member of tlhe Minnesota Governor's Commission on the Status of Women, and has produced two television programs on public school financing.
In addition to being Dean '.lf the School of Medicine, University of Colorado, Dr. Talmage has been professor of Medicine, profe,;sor of Mic:robiology, and chairman of the latteJr department.
November 10, 1970
Researcher Finds That Sudden Deafness May Be Indicator of Systemic Disease
Sudden deafness can b<' an indicator of various systemic diseases, a researcher at the University of Michigan ha~ found. While other scientists have suspected this, many researchers considered sudden deafness to Ix, u. problem of the inner eair or C>f the temporal bone, rthe bone a,t the base and sides of the skull rthat contains the organs of hearing.
In a study of 40 patie11ts with sudden deafness, the investigator found that 22 had a systemic disorder that could affect hearing.
Dr. Burton F. ,Jaffe conducted the study over a 5-year period at the University of Mich~gan Medical Center in Ann A1·bor. It was supported in part by the National Institute of Neurologic.al Diseases and Stroke.
The patients included one man w~th fat emboli, clot,s which travel through the bloodstream. When these clots reach a very small blood vessel they get stuck and block the vessel.
Eleven of the sudden deafness patients had hypercoagulation, aJ1
accelerated ra.te of blood clotting which can produce a thrombosis or clot somewhere in the blood vessels. And another 10 patients ha<l upper respil"atory infections that could have affected their hearing.
Specia list Ale rts Internist
Dr. Jaffe pointed out that his findings a.re evidence that physicians should begin to think of the ear much as they do the eye--as a sensitive indic.atoT of blood vessel pathology or other systemic disease.
He added that the otorhinolaryng,ologist, the physician who specializes in ear, nose, and throat problems, c.an be bhe key specialist to alert the il'lJternisrt; to serious systemic dhorders.
When Dr. Jaffe began his study, he kept in mind the previously stated theory that sudden deafness could result from the sudden closing off (occlusion) of a blood vessel.
1fost of his patients <lid not have evidence of vasculro: diseases such as diabetes, hardening of the arteries or hig,h blood pressu1·e.
Blood tests ,showed tha:t 11 pahlents did have hype1,coa.gulation and three patients had ,cha.nges in vision which occurred sud-denly, indicaiting vascular problems.
Another patient with sudden deafness died, and examination of the inner ears showed evidence of plugs in the blood vessels.
Although the precise relationship between plugs in the blood vessels and sudden deafness is not yet known, these findings alerted phy,sicians to the possibility that the pa~ tients had ,a blood dot somewhere in their system.
The single patient with sudden deafness due to fat emboli was a medical student who had been in a moto1·cycle ae0ident. The deafness developed 5 days after the a.ccident and followed other symptoms of fat emboli including confusion, 1-espiratory problems, a rash, and vision pmblems. Medi.cal therapy cleared up the fat emboli and his heari11g problems s lowly disappeared.
Infections Prominent
In 10 of the other patients wit h sudden deafness, Dr. Jaffe found a fourfold or greater rise in blood antibodies indicating a recent infection-in six cases to mycoplaiSma pneumo•niae, in three cases to adenovirus, and in one to para.influe,nza.
In looking back over the medical literature, he found that one out of every three pauients with sudden deafnoss had had a recent mild upper respira,tory infection.
In most of these infections, the virus gets into the blood stream and damage to the inner ear may be a local manifestation of thls infeetion.
Further study showed that onethird C>f the 40 patients had some damage to both ears during the ep,isode of sudden deafness. Dr. Jaffe noted that dama.ge to both ears is further ewdernce 1,hat a systemic disease is rnvolved.
THE NIH RECORD
Dr. Walker Is Appointed Deputy Chief, Baltimore Cancer Research Center
Dr. Michael D. Walker was recently named deput y chief of the National Cancer Institute's Baltimore Cancer Resewch Centei-.
He will also mtain his posation as head of the Section of Neurological Surgery at the Baltimore facility.
Dr. Jerome B. Block, ehief of the BCRC and a,;sociate direclor of the Clinical Oenter, commended Dr. Walker's outstanding achievemen,ts in the clinical investlig1a.tion of brain cancer and other malignancies of the central nervous system.
In his new posit,ion, D1·. Walker will play a prominent role in the overall management of prog1:am efforts.
Serve s at Lahey Clinic
A graduate of Yale Univemity and Roston University School of Medi0ine, he served as a Fellow in Neurosurgery at the La.hey Clinic in Boston.
Before joining NIH in 1965, he was clinical instructor in Neui-o-
Dr. Walker developed and choired the Brain Tumor Study Group.
surgery at Harvard l.'niversity Medical School.
Dr. Walker began his Federal career as a medical officer in NCI's Li1boratory of Chemical Pha1·macology.
His primary research interests inv:ilve the development of laboratory anima.J models of brain tumors and the pharmacology of anticancer drugs with respc-ct to normal brain and cerebrospinaJ fluid and bi-ain tumors.
Yerkes Center Research Described in New Atlas
Otis Ducke r (center left), c hief, Supply Ope rations Section, SMB, presents cash for Superior Pe rformance Award to Walte r Chakwin, Mate rie l Storoge Unit h ead, ond unit employees. The grou p displayed outstanding dedicotion in m cving the SMB Central Storeroom from the NIH rese rvation to the Danae Building in Rockville without inte rruption to service. Haywood L. Turner who contributed much to the success of the move, was not present far the picture .
A reeently published book, The Atlas of Comparative Primate Hematology, by Dr. Hans-Jurg Huser, i.s based on work he did as a visim.ng scientist durmg 1966-67 at the Yerkes Regional Primate Research Center in Atlanta, Ga.
The cente1.' is supported by the Division of Research Resources.
The referen.ce w'Ork oompa.r"-5 t,he blood and bone ma.11:ow of nonhuman primates. It includes materi-
al rarely found in conventional references on hematology, such as electron microscopy and histochemistry of leukocytes.
The book is the first on hematology to use computer methods for evaluation of nrn·mal values, a method described by Dr. Geoffrey Bourne, Director of the Yerkes Center, as vastly superior to the cons,tant model used thus far.
THE NIH RECORD
3 Executives Appointed To Top-Level NCI Posts
Three executive app()intments in the National Cancer Institute have been annour,ced: Dr. Frank J. Rauscher, Jr. becomes scientific director for Etiology; Louis M. Ca.rrese, associate director for Progre.m Planning and Analysis, and Calvin B. Baldwin, Jr., executive off-icer.
Dr. Raus~her, an autho-rity in the field of viral oncology, was formerly acting scientific di- Dr. Rauscher rector for Etiology (see The NIH Record, Nov. 26, 1969).
He is noted for his quantitative studies on host factor.s in oncoge,nesi.s associated with tumor viruses, including a murine leukemia virus whiclh he disoovcrcd.
Co- Deve lops Plannin9 Method
Mr. Can-ese joQne<l NCI in 1962. As program planning officer and late,r deputy associate director fol' Program, he developed methods for research planning, analysis, and coordination.
He is co-<leve.Ioper of the Convergence Technique-,an innovative planning method uniquely suited to research planning-which has been used in the formulabion of plans fo1· major cancer research programs and by several medical organizations.
Mr. Carrese Mr. Baldwin
Mr. Carrese received his bachelors and masters def/,'rees from the Unive1·sity of Rochester, and has completed ihe courses for his Ph.D. in Industrial Sociology at the University of Maryland.
Mr. Baldwin is a Phi Beta Kappa graduate of the University of North Carolina. He rece·ived his M.A. degree in Public Administration from Harvard University.
Joins N IH in 1953
Since his first NIH appointment as management analyst, Office of the Director, in 1963, he has se.TVed in administrative posi,bions with the Division of General Medical Sciences and the Division of Research Grants.
Mr. Baldwin's most recent posit was as executive officer of the National Institute of Child Health and Human Development.
November 10, ] 970
2 Studies Seek to Pinpoint Mechanism By Which Bacteria Destroy Gum Tissue
Two studies to pinpoint the mechanism by whdch bacteria living in the mouth destroy tooth-supporting tissues in periodontal disease (pyorrhea) are under way ait the Forsyth Dental Center in Boston. Periodontal disease is the chief ea.use of tooth loss in adults.
The National Irwtitute of Dental Research 1~s awa1'ded grants to Ors. James T. Irving and Philias R. Garant for the first year of their studies. The vesearchers hope to discover t he cause of this widespread disease so tha.t it can 1:,e prevented.
Periodontal disease begins insidiously. 'l'he gums become red and inflamed and pull away from the teeth. Pocke<t.s form near the gum line. 'rhen the gums ulcerate and bleed, pockefa dcepe,n, and inflammation sp,reads.
At the same time, the bone underlying the gums is eaten away or rnsorbed by bone-destroying cells. Because the teeth are normally held firm by this alveolru· bone, its deskuction leaves the teeth so wobbly that in time they fall out.
These symptoms-including the s.cve1·e bone loss-can be induced in rats that are raised in a germ-free environment by infecting them with bacteria from human periodontal pockets. Otherwise, the germfree animals show only very s low bone deterioration with age.
Tissues Compared
By comparing tissues in rats reared free of germs throughout the·ir lives with their litt.el' mates infected later with known germs, the researchers hope to pick out the disease-ca.using organisms and pinpoint the mechanisms by which they de.'ltroy the toobh"\Supporting tissues .
Although formation of a bacterial mat (dental plaque) o.n teeth around and under11eath the gum line is believed a cause of the condition, exactly how this ma.t tl'iggers bone destruction r emains a mystery.
According to earlier work by Dr. Irving and others, bone-destroying cells are attracted to bone aftel' its organic framework undergoes certain chemical changes.
Dr. Irving hopes to detel'mine whcbher bacterial factors are responsible for those bone changes and whethe1· bacteria work havoc on the bone by first causing inflammation.
This procoss is believed to be involved because inflamed tissue is always present near the resorbing alveolar bone.
To determine whether bacteria are essential to bone loss, the scientists will compare ~veral types of rat bone after each has been exposed to inflammation caused by pure cultures of bacteria from periodontal pockets, or by certain bacterial pa:rt.s or products, or by such sterile inflammatory agents as •turpentine.
Dr. Garant will use the eledron microscope to study the u ltrastructural evtmts taking plaee within booth~supporting tissues of the same expel'imental animals. The knowledge gained through the cellular a nd subcellular events occurring •in t he experimental animals will be used t o find the mechanisms I'esponsible for tissue damage.
Dr. Garant will al;;o study lymph nodes of the head as well as the spleen to see how the microbes affect; the body's immune system.
New Studies Mode Possible
To distinguish tissue damage caused b y the bacteria themselves from that caused by the body's immune response to them, the scientists will give some of the rats drug's lihat dampen the immune response before infec.ting them with the microbes from human pe1·iodontal pocket.s.
By using germ-free rats exposed to known organisms only, the Forsyth scientist.<, can study many aspects of periodont al disease that cannot be studied in humans.
Should their discoveries lead to new ways to prevent periodontal disease, they will benefit the threeof-every-four adults in this country who have some form of either gingivitis (gum inflammation) or periodontal disease.
DR. BERLINER (Contin1tcd front Pcigc 1)
the chemical treatment of human malaria, on the renal regulation 0f acid-base balance, on the me,!hanisms by which urine is concentrated and diluted, on tJhe C<'llular exchanges among potassium, sodium and hydrogen, and on the trans-· port of biologically important molecules across cellulru· membranes.
R e has contributed to textbooks on medicine and physiology and has published more than 100 pape1·s.
Serves on Many Journols
Dr. Berliner has served on the editorial board of the Heart Association's monthly journal, Circulalion Research, foi- more than a decade.
He has also been on the editorial boards of AHA's Circulation, and the American Journal of Physiolo.c;y, and Journal of Clinicr1l Jnvestigcition.
A member of the National Academy of Scie,nce,s since 1968, Dr. Berliner received Modern Medicine's Distinguished Achievement Award in 1969; the Bicentennial Medal of Columbia University's College of Physicians and Surgeons in 1967, and its Alumni Award in
Page 5
Dr. Huber Joins NINOS; New Associate Director Served on Nat'I Council
Dr. \Nar1·en V. Huber, formerly chief of Neurology of the Veterans Administration, has been named associa;te director for Collaborative and Field Research, National Institute of Neurological Diseases and Stroke.
While coordinating the V A's nationw ide neurology program during the past 10 yea.rs, Dr. Huber worked closely with NIH and se:rved on the NINDS National Advisory Council.
Dr. Huber will be responsible for 3 major ai,e,as: collab01·ative perinatal research, correlruting factors in pregnancy and early life causing cereb1,al palsy, mental retardation, and o\lhe1· neurological and sensory disorders; epidemiological research, investigating the role of so,cial, geographic, and genetic factors in neurological diseases, and special projects, including collaborative studies on epilepsy and head injury.
Wartime Se rvice Noted
Dr. Huber completed his premedical training at Columb<ia University, and received his M.D. from Long I sland College of Medicine in 1933.
During World War 11 he served as chief of Neurology and Psychiatry in U.S. Army hospitals in Ire-
Or. Huber will supe rvise N INOS contracts ond 9ronts allocated to fie ld ond collaborative research.
land, England, and France. Dr. Huber later served as chief of Neurology at Brooke Army Hospital, San Antonio, Tex. from 1950 to 1953.
From 1953 to 1958 he was chief of Neurology in VA ho&pitals in Richmond and Denver. In 1968 Dr. Huber served as Director of Research for t he Lynchburg Training School and Hospital Colony, Virg·inia, and then returned to the VA h ospital in Denver until he came to the VA National Office in Washington in 1960.
1966. He also rnceived the Homer W.
Smith Award in Renal Physiology in 1965, and the HEW Distinguished Service Award in 1962.
Page 6 November 10, 1970
Death or Damage From lead Poisoning Reduced by Early Testing and Treatment
Increased testing for lead poisoning in children has caused a drastic reduction in deaths and brain damage from this environmental hazard ove1· the past 5 years, according to an NIH-supp.oi:ted investigator at the Johns Hopkins University School of Medicine. than 5 percent.
Dr. J. Julian Chisolm, a research Following treatment with BAL scientist as well as associate chief and EDT A, whkh requires hospitalof pediatrics at Baltimore, Md., ization in the center, the child is City Hospitals, believes greater treated with another, investigationawareness of danger and early al, drug, d-penicillamine. Peniciltreatment along with the increased !amine removes the lead from the testing bring about the reduced tissues where it is stored. death rate. Penici!lamine treatment is con-
Lead poisoning is far from being tinued for long periods, sometimes wiped out though, said Dr. OhJsolm, years, to remove all the lead. who ha~ just completed a one-year "If we had good screening and study in the Johns Hopkins clinical early detection, we could cut the research center for children, sup- time of pen:icillamine treaitment ported by the Division of Research drastically," Dr. Chisolm said, Resources. adding:
Seeks Early Detection
The study was aimed at finding an easy method of detecting the disease in its early stages. The longer a child goes undiagnosed, he noted, the more likely he is to have brain damage.
Almost half the chi ldren who recover from acute lead poisoning have brain damage, which causes convulsions, irritability, and subtle learning defects.
Fot· children who have a recurrence of severe lead poisoning, the 1·ate o( brain damage is virtually 100 percent.
Lead poisoning strikes mainly among children who live in dilapidated urban housing and contract the disease by eating leaded paint flaking from walls and interior sut·faoes.
Although the true incidence of this disease is not known, surveys have shown that as many as 5 percent of the children in these socalled "lead belts" may have lead poisoning.
In his study, Dr. Chisolm found that the only completely reliable method of detecting lead poisoning is a blood test. However, this requires a sample from a vein, a diflicult procedure in small children.
Refining Procedure
Dr. Chisolm is now trying to refine this procedure, and hopes to reduce the amount necessary to a few drops obtained from pricking a finger.
He believes this ''micro test" will furnish an effective method of screening for lead poisoning among high risk populations to detect the disease before any symptoms are present.
"If the child continues to ingest lead, the drugs don't do any good, and he has to be hospitalized and we have to start all over again."
Dr. Warren G. Stamp Appointed To Advisory Council of NIGMS
Dr. Warren G. Stamp has been appointed to the National Advisory General Medical Seiences Council. His term will nm through September 1974.
Dr. Stamp is chairman of the De, partment of Orthopedic Surgery at the Univen·sity of Virginia Hospital in Charlottesville, Va.
l /
Fed'I Professional Ass'n Goals Noted by Speakers At Information Meeting
"Professional employees nend a mechanism for bringing their views and desires to bear on the legislation and regulations that affect bheir work and environment," Dr. Allen V. Asitin told NIH employees who attended the Federal Professional Association information meeting held at Wilson Hall on Oct. 21.
Dr. Astin, former Director of the National Bureau of Standards, was instrumental in starting the large FP A chapter there.
Several past presidents of other FP A chapters spoke, tracing the organization's past histm·y and discussing its present goals.
Improveme nts Suggested
These include establishment of a separate classifica,tion system for profess.ional and executive employees, improvement of their educational opportunities, and more effective use of available administrative authority to vary the duty hours of such employees.
Dr. Edwin D. Becker, NlAMD, who was <>hairman. of the meeting introduced other FPA notables.
He said that, based on interest shown, the committee would proceed at once toward a meeting for the a ctual organization of the NIH/ NIMII chapter of FPA.
I At the clinical 1·esearch center,
Dr. Chisolm treats victims with two chelating agents in combination. These agents, known as BAL and EDTA, bind the lead in the blood and pass it out of the body.
This treatment has helped to cut the death rate for severe lead poisoning from 30 percent to less
NLM team wins championship of NIH Golf Association by beating the Mash ies one-u p in o sudden-death play-off. During the Sth year of the Associat ion, which is su pported by R&W, some 1 SO playe rs (1 2 teams) competed in weekly matches during the 2 2-week season, plus several other 18-hole outings. T rophies were presented at the annua l ba nq uet he ld jointly with the NIH Ladies Golf Association . Winn ing team members (I to r) a re: front row, Frank Poh, Jock W olk, Capt . Pa ul Kelly, Co rlton Su llivan, George Russell; secand row, Lar ry Coffin, Bob Ca pone, Art Robinson, Ron Taylor, Nate Markfield; third row, Bill Caldwell, Tom Minton, Ken Carney.
THE NIH RECORD
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Dr. J ohn C. Greene, Director of the ye, Division of Dental Health, BHME, has apJ been appointed Assistant Surgean thE Gene ral, PHS. He is wide ly known os 1 co-author a nd developer of the Orol art Hygiene Index and the Simplified Orol col Hygiene Index, used by researche rs for To evaluating orol cleanliness. lea
2 Nobel Prize Winners, Drs. Leloir and Borlaug, Have Ties With NIH
Two more Nobel prize winners of 1970 have ties with N IH- Dr. Luis F. Leloir of Argentina, who won the Nobel Prize in Chemistry, and Dr. Norman A. Borlaug, winner of the Nobel Peace Prize.
Dr. Leloir was honored "for his discovery of sugarnucleotides and their role in ,the biosynthesis of carbohydrates."
His grant from NIH, now in its 18th year, is administered by the National In~titute of General Medical Sciences.
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outstanding biochemists and is re<:ognized for his co11tributions bo the trc understanding of carbohydrate me- re: babolism, according to Dr. DeWitt pr, Stetten, Director of NIGMS. da
With Institute support, Dr. Leloir has demonstrated in grell!t detail the be l>as.ic biochemical stel)S required fur er, the enzymabi.c breakdown of sugars no in the body and the s.ynthesis of glycogen and starch. i~,
'l'hese discoveries may have im- riE portant medical application.
Dr. Leloir is Director of the lnsbituto de Invest.igaciones Bioquim- .Cu icas in Buenos Aires. Currently he mi is investigating hormonal regula- in tion of sugar metabolism and the re enzymes and coenzymes which act be on particular sugar particles, the A~ hexosephosphates.
Dr. Borlaug served on the malnu- eh trition panels of the U.S. Japan m, Cooperative Medical Science Pro- th gram in 1965 and 1966. (s
This program is now adminis- He tered by the N aitional Institute of Allergy and Infectious D-iseases in : collaboration with the National Institute of Arthritis and Metabolic ~u Diseases.
The American agricultural exp ert developed a dwarf strain of op wheat which is helping to supply ar grains to hungry nations.
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THE NIH RECORD
NERVOUS SYSTEM (C<mti.,.ued front Page 1)
some external mechanical device. For example, electrical l!;jgnals
from the brain could activate a me-· chanical shovel capable of liftin~ morie than could a hand-operated one. Or, such a system could directly control a wheelchair.
"Actually," said Dr. Frank, "in the long range view, I think I am most excited by the p-0ssibility of extending human capability beyor.d the normal."
Lob Explores Possibilities
Dr. Frank's lab was created 3 years ago to explore possibilities of applying basic information about the nervous system.
Ultimately, the scientists hope, artificial devices can be entirely controlled by the nervous system. To do this, though, they must first learn how the brain directs motor behavior through patterns of nerve impulses.
By recording directly from brain cells of the motor cortex in animals, laboratory members are learning the properties of these firing patterns.
In beginning these studies, the investigators are faced with a primary problem--developing electrodes (.to measure or stimulate electrical activity) which could be successfully implanted in the brain.
Difficult Engineering Problem This is a tremendous engineering
problem because the eleotrode must be flexible enough to move when the brain moves (so that it does not damage surrounding tissues), yet hard enough to withstand implantation without bending.
Furthermore, if imp,lanted electrodes are found to produce tissue reactions, they or their breakdown products could possibly cause bra.in damage.
Implanted electrodes are already being used in some cases to dull excruciating chronic pain or to diagn-0se brain damage. While they may p1·oduce some damage themselves, their advantages outweigh the risks.
NINDS grantees have successfully used an implanted rad,io transmitter to signal increased pressure in the brains of persons with hyd:rocep hal u:s. Such devices could also be used to transmit nerve signals.
Approach Doubted Other grantees are implanting
electrodes directly into paralyzed muscles in an attempt to stiimulart:e them and prevent degeneration (such as can result from a stroke). However, Dr. Frank notes that this approach may not be succesful because, "I suspect that muscles re~ quire connections to healthy nerves if they are to remain functional."
Still anot:her device under development by grantees is a myoe.Jectric arm which Would use electrical po-
November 10, 19i0
Dr. Wiley H. Mosley (center) receives the PHS Meritorious Se rvice Medal from Dr. Robert Q. Marston, NIH Director. Dr. Mosley, chief of the Epidemiology Section of NIAID's Pakiston-SEATO Cholera Research Loborotory in Dacco, East Pakistan, was give n the oword for "his significant contributions to knowledge of the immunology and epidemiology of cholera resu !ting from his outstonding ond dedicated work." Atte nding the cere mony was his fothe r, Dr. Kirk T. Mosley, who is associoted with the Ford Foundation in Calcutta, India.
Swedish Council Offers 2 Research Fellowships The Swedish Medical Research
Council is sponsoring two postdoctoral research fellowships-to be awarded in 1971 to qualified biomedical scientists who are U.S. citizens.
The fellowships will cover 12 months of research training in basic or clinical sciences in a Government-supported institution in Sweden.
To be eligible, candida.tes must have done independent research in one of the health sciences for ad: least 2 of the last 4 years.
Aptitude Must Be Shown Evidence of research and apti
tude ma.y be demonstrated in the form of a scientific bibliography, reports of seientific publications, and references from pe1-sons familiar wibh the applicant's background.
Applicants must also show that they have been accepted by a Swedish training institubion and by a p:recepbor.
A Facilities Oommitment Sbate-
tentials from surrounding muscles to control movemen,t of the hand 01· arm.
Such devices are thought to hold great promise because the wearer would merely attempt to make the same motions as if he had a normal limb.
For more complex control devices, Dr. Frank indicates that the wearer will have to learn a code of specific muscle or nervous activity.
ment must clearly state that the Swedish institution will provide facilities for the duration of the Fellow's stay.
The stipend will amount to $5,500 or $6,000, depending on the scientist's qualifica.tions and experience. Fellows wil also receive an additional $,500 per year for ea.ch dependent whether that dependent goes to Sweden or remains in the United States.
The council will reimburse Fellows for round-trip travel costs for themselves and their immediate families. During their stay they may also accept sabbatical salary, royalties, or other income if r ep-0rted in the application.
Scientists may obtain application forms and further information from the International Fellowships Section, Fogarty International Center,
Page 7
Artificial Kidney-Chronic Uremia Procee dings List Promising Innovations
Proceedings of the third annual meeting of Artificial Kidney-Chronic Uremia Program contractors held las:t January has been published by the National Institute of Arthritis and Metabolic Diseases.
The publication highlights research accomplishmeruts in principal areas of the program including:
Progrom Areas Listed Membranes a.nd ma.ss transfer;
hardware and instrumentation; blood cannulas and biologically compatible materials, and toxic factors in w·emia, dietary management of chronic end-stage renal disease, and clinic~! studies in uremia.
Innovations included a,i·e: development of a new generation of compact artificial kidneys, the so-called "hollow fiber dialyzers ;" easy-touse preste.rilized "envelope dialyzers," and a clinicially successful method of automated peritoneal dialysis with pennanently implanted access devices to the abdominal cavity.
Also, an inexpensive method of manufacturing dialyzers- which up to now have been expensivethrough pressUJ'e molding in the fa:shion of phonograph records, and the first successful dialysis of patients with membranes other than cellophane.
The proceedings are being distributed to persons employed in relevant fields. Since they weI-e first issued in 1968, the proceedings have become de'finitive source material.
NIH, Bethesda, Md. 20014. Forms must be completed and re
turned to the Fogarty Center on or before Feb. 1, 1971.
Final selection will be made at the April 1971 meeting of the Swedish :\fe<lical Research Council.
"One important key," he ex-• plained, "is ,to find out if man can learn to control the activity of individual nerve cells. Once this can be done on a broad scale, the possibilities for neural control of exoornal devices are unlimited."
Clinical Center staff members enjoy the annual Appreciation Porty given by Nursing Department supervisory personnel. L to r are: Geroldine Ellis, Adam Chornesky, Mildred Claasen, Virginia Murphy, Morgoret Wilt, and Rosalie Winkler. This year the Halloween spirit enlivened the occasion-complete with fresh cider, ginge rbread, doughnuts, and apples .
November 10, 1970 THE NIH RECORD
On the United Nations' 2Sth Annive rsary, Oct. 24, the Fogarty International Center gove an informal reception for NIH Visiting Scientists and International Postdoctoral Fellows. It enabled the foreign scientists ot NIH to get to know
each other ond the FIC staff, ond become better ocquointed with the Center's facilities. About 120 scie ntists, their wives, and children attended the reception at the Inte rnationa l Visitors Center, Bldg. 16A.
Lyman Moore Appointed Executive Officer, NHLI
Chemotherapists Report On 2 Anticancer Drugs Dr. Dorfman Receives Award for His Research Supported by NICHD
Appointment of Lyman !\foore as executive officer of t he National Hear-t and Lung Institute was recently announced by Dr. Theooore Cooper, l ns,t;atute Director.
After receiving his B.A. degree fre>m Princeton University in 1936, Mr . Moore serve,d for a year as assistant in Instruction at the Unive;rsity's Woodrow Wilson School of Public and I nternational Affail'S.
He served for 2 years as program officer of International Rouse in Kew York City, thtm entered the University of Minnesota, where he earned his M.A. in 1940.
That same year Mr. Moore joined the Bureau of the Budget. Subse-
Mr. Moore has been active in the youth hoste ling moveme nt and is currently Notional President of Americon Youth Hostels.
quently he held numerous administrative posts in HEW.
In addition to his Federal service, Mr. Moore has been a management consultant to a private firm a11d a professorial lecturnr at American University.
His profession.al affiliations include the Society for the Advancement of Management, of which he was vice president for membership
A conference to advise practicing physiciians on research reeults achieved wibh the anticancer drugs ortho pa.ra'-DDD and mithramycin was sponsored by the Chemotherapy Program, National Cancer Institute, Nov. 5-6 in the Jack Masur Auditorium of t he Clinical Center.
Both of these anticancer drugs were a,p proved earlier this year as prescription drugs by the Food and Drug Administrat:Jion.
Ortho pa.ra'-DDD or mitlotane is marketed as "Lysodren" by Calbiochem for use in advanced cancer of the adrenal gland. Mibhramycin, useful in some cases of inoperable canoor of the testes, is produced b~• Chas. Pfizer & Co. under the trade name "l\fithracin."
The opening session, devoted to the antibiotic mithramycin, was chair ed by Dr. C. Gordon Zubrod, scientific director for ChemoVherapy, NCI. Evaluaitions of the drug in testicular cancer, in Paget's disease of the bone, and in problems of calcium imbalance were presented.
Dr. Stephen K. Carter, chief of the Cancer Therapy EvaJuaition Branch, moderated an afternoon symposium on the therapy of testicular tumors, including treatment with surgery, radiothera.py, and drugs.
A series of reports on the development and use of ortho pa.ra'DDD, a drug related to the insecticide DDT, ·was also presented.
This included a description of the effects of the drug in advanced cancer of the adrenal oortex and in Cushing's disease, a rare disease of abno1·mal growth chm:•acteristics
(1966-68), vice-president for Intersociety Relations (1968-69), and past president of the Washington chapter.
He is also a fellow of the American Public Health Assooiation and a member o:f other public and health administration societiies.
sometimes due to an adrenal tumor. The session was chaired by Dr.
Saul A. Shepartz, associate scientific tl.ire,~tor and chief, Cancer Chemotherapy National Service Center.
Drs. Benditt and Riley Join NIEHS Committee
Drs. Earl Philip Benditt and Richard Loi-d Riley have been appointed to the Environmental Health Seiences Advisory Committee for terms ending June 30, 1974.
Dr. Benditt is chairman of the Department of Pathology in the School of Medicine at the University of Wa&hingbon.
He served on the editorial board of Laborntory Inve.~tigation in 1962, on Journnl of Experimentnl and Molecular Pcithology from 1962 to the present, and as editor of Electron Mieroscovic .Atlas of Pntho/oyy in 1066.
Dr. Riley is professor of Environmental Medicine in the School of Hygiene and Public Health at Jolms Hopkins University.
He has held positions at Colum-
Dr. Albert Dorfman, NICHD grantee and Director of a center supported by NIH, has received the annual Borden Award.
The award, for outstanding achievement in research relating to nutrition and/ or t he develop,ment of infants and children, consists of $1,000 and a gold medal.
Dr. Dorfman is professor and chairman of the Department of Pediatrics, University of Chicago Pritzker School of )'.iedicine.
He is also Director of the Joseph P. Kennedy, Jr. Mental Retardation Research Center in Chicago. The center was const ructed with NIH funds, and is supported by tJhe National Institute of Child Health and Human Development.
Dr. Dorfman has provided a greater understanding of the molecular biology of connective tissue and its causative relationship to a variety of genetic disorders.
bia University, Bellevue Hospital, New York, and t he Institute of Industrial Medicine at N.Y.U.
TO JOI N THE " DAVIS PLAN" -- make a Clinical Center patient's life happier
during the Christmas holidays, and all through the year -- please use this form.
Gifts are ta>< deductible.
Encle>sed is a gift of S--• (Make checks payable to NIH Patient Welfare
Fund. )
Send to: Mr. James Davis, director, Office of Administrative Services, Bldg. 31, Room 1C02 -- or Mr. John Roatch, chief, Social Work Department, Clinical Center, Room lN-250.
Donor's name: _______________________ _
Inst itute/Division: ___ ________________ __ _
Bldg. & Room No.: _____________ _____ _ __ _
Instead of shopping for Christmas cords for colleagues, NIH employees are urged to ioin the " Oavis Pion." This form was designed to moke donating thot money to the CC Pat ie nt Welfare Fund eas ier.