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Nose, olfactory region and the sinuses (L1)

2012

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Nose

Nose wings

Olfactory mucosanasal conchae

Respiratory mucosa

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Nasal ala lamina propria

hyaline cartilage

mixed glands

hair

skeletal muscle

unkertinized stratified epithelium

Skin -OUTSIDE

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Respiratory mucosa of nasal cavity

Ciliated pseudostratified cylindrical epithelium

artery

mixed glands

large veins

bone

Mucous goblet cells

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Olfactory region Located in respiratory part of the nasal cavity Begins at the front of the anterior end of the superior

concha and extends posterior for about 1 cm Extends laterally from the roof over the largest part of

the superior concha and medially for about 1 cm over the nasal septum

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Olfactory mucosa

OLFACTORY EPITHELIUM

Olfactory nerve fibers

Large veins

bone

Gland of Bowman

LAMINA PROPRIA

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Olfactory epithelium

Cell types 1. Pseudostratified

cylindrical epithelium 2. Olfactory cells 3. Support cells 4. Basal cells

Olfactory cilia

Olfactory vesicledendriteSupport cell

Olfactory cell body

Basal cell

axon

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Cell type Structure and functionPseudostratified

cylindrical epithelium

Ciliated (about 300 cilia on apical surface)

Mucus transport

Olfactory cells Bipolar neurons, at apex 6-8 cilia

Very long non motile

Smell, generates action potential transmits impulse

Support cells Broad cilindrical apexs with narrow bases

Microvilli are submerge in fluid layer

Well developed junctional complexes

Basal cells Small, lie on basal lamina

Do not extend to surface

Generative stem cells

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Lamina propria

Contains many veins - usually flat (Allergies - veins fill with blood and cause a blocked nose)

Contains tubulo-alveolar glands namely Bowman’s glands that secrete a thin watery substance that facilitates smell stimuli

Rest of the lamina propria contains mixed glands

The lamina propria is located against the perichondrium of the hyaline cartilage

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Paranasal sinusesMucosaEpithelium: 1. Pseudostratified cylindrical with cilia 2. Thinner than nasal epithelium3. Less goblet cells and mixed glands 4. Thinner basement membrane

Lamina propria is thin and rests against the periosteum of the bone