Normal kidney This fat is normal - medicinebau.com · Perinuclear halo is characteristic .. …the...

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Normal kidney This fat is normal

Transcript of Normal kidney This fat is normal - medicinebau.com · Perinuclear halo is characteristic .. …the...

Normal kidney This fat is normal

Simple cysts

Normal kidney but still having the fetal lobulated pattern (normal)

Acute inflammatory cells in interstitium Acute inflammatory cells attacking the tubules

glomerulus

Acute pyelonephritis

Acute inflammatory cells attacking the tubule

Acute inflammatory cells in interstitium

Acute pyelonephritis

Acute inflammatory cells in interstitium Acute pyelonephritis

Necrotizing papillitis (papillary necrosis)…a special pattern of acute pyelonephritis especially in diabetics

Normal transitional epithelium…from adjacent renal calyces

Candida as highlighted by PAS stain

Pyelonephritis due to candida

Chronic pyelonephritis (as you see lymphocytes in interstitium)

Chronic pyelonephritis (as you see lymphocytes, plasma cells & few eosinophils in interstitium)

Plasma cell

Xanthogranulomatous pyelonephritis (a complication of long standing chronic pyelonephritis)…as you see it may appear as a suspicious mass

Foamy macrophages

lymphocyte

Epithelioid histiocytes

Xanthogranulomatous pyelonephritis

Renal oncocytoma.. Bland nuclei and bulky fine granular eosinophilic cytoplasm

Renal oncocytoma.. Bland nuclei and bulky fine granular eosinophilic cytoplasm

Renal oncocytoma.. Bland nuclei and bulky fine granular eosinophilic cytoplasm

Clear cell renal cell carcinoma …clear cytoplasm due to fat & glycogen …the nuclei in this example are low grade (we have Fuhrman grading for renal cell carcinoma especially used for clear cell type)

Adjacent normal tubules Clear cell renal cell carcinoma ..higher grade than the previous example

Papillary RCC Fibrovascular core

Malignant cells

Fibrovascular core

Papillary RCC

Papillary RCC The core here is filled with foamy macrophages and this is common to occur in papillary RCC

Malignant cells

Chromophobe RCC

Perinuclear halo is characteristic .. …the nuclei are atypical (hyperchromatic with irregular nuclear contours)

Perinuclear halo is characteristic …the nuclei are atypical (hyperchromatic with irregular nuclear contours)

Chromophobe RCC

Same notes as The previous 2 examples

Chromophobe RCC

Chromophobe RCC Hale’s colloidal iron special stain.. It stains mucin blue

Umbrella cells

Normal transitional cell epithelium (urothelium)

Hyperchromatic cells Urothelial carcinoma in situ: enlarged nuclei, pleomorphism, hyperchromasia, prominent nucleoli & mitoses… Cells with these features are seen in the urothelium without BM disruption

Urothelial carcinoma in situ: enlarged nuclei, pleomorphism, hyperchromasia, prominent nucleoli & mitoses… Cells with these features are seen in the urothelium without BM disruption

Urothelial carcinoma in situ: enlarged nuclei, pleomorphism, hyperchromasia, prominent nucleoli & mitoses… Cells with these features are seen in the urothelium without BM disruption

Papillary urothelial carcinoma

Papillary urothelial carcinoma

Papillary urothelial carcinoma

Papillary urothelial carcinoma

A large papilla

Fibrovascular core