2005

C-C bond formationO 0282 Nitrogen Ligands: The Transition Metal Catalyzed Reaction of Aryl Halides with

Olefins (Mizoroki—Heck), Phenylboronic Acid (Suzuki Coupling) and Buch-wald—Hartwig Amination, New Catalysts and Effect of Cocatalysts—Aryl Halide Activation. Part 1. — A variety of nitrogen ligands are tested in the palladium-cata-lyzed Mizoroki—Heck reaction, Suzuki cross coupling and Buchwald—Hartwig ami-nation of aryl halides. Good results are achieved with ferrocenyl oxime-based, dimeth-ylaminotoluene-based and acetophenone oxime-based ligands, comparable to phos-phor ligands. Activation of aryl bromides as well as aryl chlorides is achieved with the new nitrogen ligands. Mizoroki—Heck reactions can readily be carried out in molten Bu4NBr as ionic liquid. — (IYER*, S.; KULKARNI, G. M.; RAMESH, C.; SATTAR, A. K.; Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem. 44 (2005) 9, 1894-1908; Div. Org. Synth., Natl. Chem. Lab., Pune 411 008, India; Eng.) — Mischke

02- 050

2005