New Harvard Peristaltic Pumps

R. Pelletier, September 2012

What is a Peristaltic Pump• Positive displacement pump• Fluid is contained within a flexible tube

fitted inside a circular pump casing • A rotor with a number of "rollers",

attached to the external circumference compresses the flexible tube.

• As the rotor turns, the part of tube under compression is pinched closed forcing the fluid to be pumped to move through the tube.

• Flow Rate depends on tubing I.D., length of tubing, and motor rpm.

Peristaltic vs. Syringe Pumps

Parameter Syringe Pump Peristaltic Pump

Accuracy High (<0.25%) Low (>1%)

Precision High Variable

Reliability High High

Needs Refill Yes (unless using valves) No

Pressure High (>1,000 psi) Low (<50 psi)

Flow Type Pulseless Pulsatile

Multichannel Yes Yes

Market Size <$50 M/year >$200 M/year

Year Developed 1950's 1880's

Peristaltic Markets

• Academic Life Science• Pharmaceutical & Biotech• Food & Flavors• Chemical Industry• Semiconductor

Near Term HA targets are Life Science and Pharmaceutical Sectors

Fluid Transfer & Volume/Time Dispensing in:

Application Areas• Large Volume Infusion• Sample Preparation• Recirculating Baths• Organ/Tissue Perfusion• Dosing/Filling• Dispensing Cell Culture Media• Large Volume Dispensing

The Harvard Peristaltic Pump• Unique Architecture – Remote configuration• Interchangeable motor/heads – Versatility and wide range

of flow rates• Digital Control - accuracy• Space Saving – use in incubators and hoods

Flow Rate Ranges - 1• P-70 Motor/Head – Low Flow perfusion and small volume

dispensing

• 5 Fluid Channels• 8 Rollers (smooth flow)• Flow from 0.001 to 70 mL/min per channel• Uses 3 collar tubing (0.13-2.79 mm ID)

Flow Rate Ranges - 2• P-230/Head – Organ/Tissue/Cellular Perfusion

• 4 Fluid Channels• 8 Rollers (smooth flow)• Flow from 0.001 to 230 mL/min per channel• Uses 2 collar tubing (0.13-3.17 mm ID)

Flow Rate Ranges - 3• P-1500/Head – Bulk Fluid Transfer/Dispensing

• 1 Fluid Channel• 4 Rollers• Flow from 0.01 to 1,500 mL/min• Uses straight tubing (0.8-8.0 mm ID)

Controller Features• HA Touch Pad User Interface• Ease of Use• Tubing Library• Calibration• Timed or Volume Dispense/Delivery• Flow Ramps• Method Storage• Combine channels function for setting total flow• Constant Pressure Mode

Quick Start Menu

Pump Settings

Settings allow for interchangeable drives/heads on one control unit

Tubing Selection

Built in library allows for the selection of HA supplied tubing or tubing of the customer’s choice

Icon indicates combined number of channels for flow rate. For example, P-70 with 2 channels selected will have maximum flow of 140 mL/min

Timed or Volume Dispense

Set Dispense by time or Volume

Method Profiles

Methods may be linked as well as stored

Advanced Options allow for methods to be tied to I/O events and time delays

Calibration

Pump calibration may be for single channel, or combined flow from multiple channels

Run Screen

Method Preview

Method when running showing status

Advanced Options & I/O Capabilities

Allow for timed start/stopRemote startSignal in or out at start/during/end of run

I/O Ports – Back Panel

Competition - 2 General Types of Peristaltic Pumps

• Type 1 - Analog (similar to HA MP-II)• Sell for $500 - $1,200• Older design electronics• Flow rates are approximate• No modern features• Difficult to calibrate• Limited I/O capability

Competition• Type 2

• Digital – Sell for $1,500 to $4,000

• Advanced electronics• Allow for calibration and direct setting of flow

Competition• Main Competitors – Digital

• Cole Parmer• Ismatec/Reglo• Watson Marlow• Wheaton Scientific

Competition• Cole Parmer mainly 1-2 channel systems

• Ismatec/Reglo multichannel systems, but low level electronics. Sold through distributors.

• Watson Marlow mainly OEM supplier of pump heads. Wheaton uses WM heads.

Competition• Compete on capabilities and application –

• Start with number of channels and flow rates• Digital capabilities• Product Configuration options

Know the competitive product and be sure you are making a valid comparison.

Competition• HA Pricing is competitive

• For P-70, HA ILP=$2,990, Competitive range is $2,900-$3,200.

• For P-230, HA ILP=$3,162, Competitive range is $3,000-$3,300

• For P-1500, HA ILP=$2,474, Competitive Range is $2,200-$2600

Not Direct Competition - low capability and low price

HA MP-IIReglo Analog Ismatec Ecoline

Masterflex CL SeriesMasterflex IP Series

Competition - Direct

Ismatec Digital Drive Ismatec Compact Digital

Masterflex Digital Drive

Masterflex LS Series Wheaton Omispense/Unispense

Accessories

• Optimized tubing sets available for all HA Models• Customers can use their own tubing• Tubing sales can be a repeat business opportunity

HA Marketing Activities• Shipments to begin in November• Brochure and web site promotion/eBlast in October• New Pump Catalog with Peristaltics in October• Exhibit at Neuroscience meeting in October• Demo pricing of 50% from ILP for distributors

Distributor Activities• Prepare web site content• Identify local beta users• Plan promotional activities

New HA Peristaltics PN Description ILP

70-7000 Complete with P-70 Head $ 2,990

70-7001 Complete with P-230 Head $ 3,162

70-7002 Complete with P-1500 Head $ 2,472

70-7003 P-70 Head/Motor Only $ 2,070

70-7004 P-230 Head/Motor Only $ 2,185

70-7005 P-1500 Head/Motor Only $ 1,725

70-7006 Controller only $ 1,092