Neurological Disorders Lesson 4.5
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Transcript of Neurological Disorders Lesson 4.5
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Neurological DisordersLesson 4.5How do circuits regulate their output?
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Do Now:
• Review last night’s homework with a partner.
• Be sure you can:
– Describe the how the SCN connects to the flip-flop switch (sleep-wake circuit).
– Describe how the activity of the SCN is regulated.
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VLPO Arousalneurons
How does the SCN connect?
Orexin neurons
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Arousalneurons
VLPO
Orexin neuronsSCN
Pineal Gland
Light
How does the SCN connect when there is light?
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VLPO
Arousalneurons
Orexin neurons
Melatonin
How does the SCN connect in darkness?
Dark
SCN
Pineal Gland
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Clock Genes
How is the activity of the SCN controlled?
Clock Proteins
Behaviors & Activity
Feedback InhibitionWhat is this type of control called?
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Why do traffic lights have both green and red lights?
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Student Model of Neuronal Control
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Excitatory neuron (1)
Inhibitory neuron (1)
Primary Neural Cell Body
Output (ON/OFF)
Input
What is this type of inhibition called?
Student Model 1
Feedback inhibition
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Excitatory neuron (1)
Inhibitory neuron (1)
Primary Neural Cell Body
Output (ON/OFF)
Inhibitory neuron (2)
Input
Excitatory neuron (2)
What is this type of inhibition called?
Student Model 2Input
Feed-forward inhibition
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Excitatory neuron
Inhibitory neuron
Primary Neural Cell Body
Output (ON/OFF)
Inhibitory neuron
Input
Excitatory neuron
Neuronal ControlInput
Feed-forward inhibition
Feedback inhibition
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Neurons in which feedback and feed-forward control is important
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Why do we need feedback and feed-forward control?
Jet Lag Seasonal Affective Disorder
Monday Morning Blues