Neural Stem Cells in Treating Diseases of the CNS

10
Neural Stem Cells in Treating Diseases of the CNS Brooke McCarthy BME 281 Fall 2011

description

Neural Stem Cells in Treating Diseases of the CNS. Brooke McCarthy BME 281 Fall 2011. Stem Cells. Undifferentiated cells Types Cell division Induced to become specialized cells Physiologically Experimentally. Neural Stem Cells. Most fundamental cell of the nervous system - PowerPoint PPT Presentation

Transcript of Neural Stem Cells in Treating Diseases of the CNS

Page 1: Neural Stem Cells in Treating Diseases of the CNS

Neural Stem Cells in Treating Diseases of the CNSBrooke McCarthyBME 281Fall 2011

Page 2: Neural Stem Cells in Treating Diseases of the CNS

Stem Cells

Undifferentiated cells

Types

Cell division

Induced to become specialized cellsPhysiologically

Experimentally

Page 3: Neural Stem Cells in Treating Diseases of the CNS

Neural Stem Cells

Most fundamental cell of the nervous system

Divides to createNeurons

Astrocytes

Oligodendroglia

Page 4: Neural Stem Cells in Treating Diseases of the CNS

CNS

Malignant glioblastomas

Multiple sclerosis

Niemann-Pick’s disease

Current treatments

Page 5: Neural Stem Cells in Treating Diseases of the CNS

NSC Therapy

Inject

Migrate

Surround

Page 6: Neural Stem Cells in Treating Diseases of the CNS

Results

Multiple sclerosis

Niemann-Pick’s disease

Still too early

Page 7: Neural Stem Cells in Treating Diseases of the CNS

Pros

Best results

Injection

Either type of stem cell

Page 8: Neural Stem Cells in Treating Diseases of the CNS

Problems

Risks

BTSC

Mutation of NSC

Largest part of brain tumors

Resists treatments

Genetic engineering

Page 9: Neural Stem Cells in Treating Diseases of the CNS

Future

Genetic engineering

Cellular origins

Other diseases

Page 10: Neural Stem Cells in Treating Diseases of the CNS

ResourcesAchanta, P. "Gliomagenesis and the Use of Neural Stem Cells in Brain Tumor Treatment." Anticancer Agents Med Chem.(2010): 121-30. Pubmed. Web. 17 Sept. 2011.

“Glioblastoma Multiforme.” Medscape. Web. 14 Sept. 2011. <http:// emedicine.medscape.com/article/283252-overview#showall>.

Taupin, P. "Potential of Neural Stem Cells for the Treatment of Brain Tumors." Clinical Medicine: Oncology. (2008): 451-54. PubMed. Web. 17 Sept. 2011.

“Stem Cell Information.” The National Institutes of Health. Web. 14 Sept. 2011. <http://stemcells.nih.gov/info/basics/basics1.asp>.

“What are Stem Cells?” Medical News Today. Web. 14 Sept. 2011.