Nervous System & Brain Endocrine System
Transcript of Nervous System & Brain Endocrine System
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Biopsychology
Nervous System & Brain
Endocrine System
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Nervous System
• Divisions of the Nervous System
• Types of Nerves
• Reflexes
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Divisions of the Nervous System
• Central NS: coordinates activity of all parts of the body
– Brain and Spinal Cord
• Peripheral NS: carries sensory and motor info to and away from the CNS
– Somatic: stimulate skeletal muscle (voluntary)
– Autonomic: stimulate smooth and heart muscles (involuntary)
• Sympathetic: pumps you up; “flight or flight”
• Parasympathetic: calms you down; “rest & digest”
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Types of Nerves
• Afferent Neurons/Sensory Nerves
– Take info from the sensory receptors to CNS
• Efferent Neurons/Motor Nerves
– Take info from CNS to muscles and glands
• Interneurons/Association Neurons
– Neurons within the CNS
– Middlemen between Afferent & Efferent
• Remember “SAME”
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Types of Nerves
• Neurons vs. Glial Cells
– Neurons send electrochemical messages
– Glial cells support and nourish neurons
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Reflexes
• Normal nervous system transmissions
– Afferent Spinal Cord Brain Spinal Cord Efferent
• Reflexes
– Afferent Interneurons in Spinal Cord Efferent
– Brain gets message after spinal cord acts
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The Neuron
• Structure of the Neuron
• Neurotransmitters
• Synaptic Transmission
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Structure of the Neuron
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Structure of the Neuron
• Dendrites
– Contain receptor sites which receive neurotransmitters from the presynaptic neuron
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Structure of the Neuron
• Soma
– aka cell body; contains cytoplasm; nucleus
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Structure of the Neuron
• Nucleus
– directs production of neurotransmitters; contains DNA
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Structure of the Neuron
• Axon
– what the neuron impulse travels down once threshold has been reached
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Structure of the Neuron
• Myelin Sheath
– fatty tissue which insulates the axon; speeds up the neural impulse; made by glial cells
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Structure of the Neuron
• Nodes of Ranvier
– the spaces on the axon which are not covered by myelin; where ion flow occurs for depolarization
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Structure of the Neuron
• Axon Terminal/Terminal Button
– contains neurotransmitters which are released after depolarization and neural impulse
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Structure of the Neuron
• Vesicles
– contained within the axon terminals, these contain neurotransmitters, they surface and release neurotransmitters after depolarization
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Structure of the Neuron
• Neurotransmitters
– contained in the vesicles, and are released into the synapse to stimulate their respective receptor sites on the postsynaptic neuron
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Structure of the Neuron
• Synapse
– fluid-filled gap between terminal buttons of the presynaptic neuron and the dendrites of the postsynaptic neuron
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Neurotransmitters
• Excitatory vs. Inhibitory
– Excitatory: makes receiving neuron MORE likely to meet threshold and have an action potential
– Inhibitory: makes receiving neuron LESS likely to meet threshold and have an action potential
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Neurotransmitters
• Serotonin
– Sleep and dreaming
– Mood
– Appetite
– Sexual behavior
– Related to Depression (too little)
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Neurotransmitters
• Acetylcholine (ACh)
– Learning
– Memory
– Voluntary motor activity
– Related to Alzheimer’s Disease (too little)
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Neurotransmitters
• Dopamine
– Involuntary motor activity
– Reward pathway
– Motivation
– Cognition
– Related to Schizophrenia (too much) and Parkinson’s Disease (too little)
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Neurotransmitters
• Gamma-Aminobutyric Acid (GABA)
– The primary inhibitory neurotransmitter in the body
– Related to anxiety and mood disorders (to little)
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Neurotransmitters
• Endorphins
– Body’s natural painkiller
– Pleasure
– Lowered levels result from opiate use
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Neurotransmitters
• Glutamate
– The primary excitatory neurotransmitter in the body
– Learning
– Memory
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Neurotransmitters
• Noradrenaline
– Aka: Norepinephrine
– Stress Response
– Blood pressure
– Heart rate
– Also a hormone
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Synaptic Transmission
• Resting Potential
– possible for the neuron to fire; axon has negative charge inside and outside is more positive; K+ are on the inside of the axon, Na+
is on the outside
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Synaptic Transmission
• Action Potential
– change in potential across the neuron’s membrane; the electrical impulse; depolarization of ions down the axon
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Synaptic Transmission
• Threshold
– minimum stimulation required to trigger a neural impulse
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Synaptic Transmission
• Depolarization
– Na+ ions rush into the cell, changing the polarity on each side of the membrane, occurs on Nodes of Ranvier
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Synaptic Transmission
• Repolarization
– after Na+ ions have rushed into the cell, K+
ions rush out of the cell to restore the balance and the original polarity
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Synaptic Transmission
• Refractory Period
– period in which the cell cannot fire while the Na+ ions and the K+ ions return to their original locations via Na+/K+ pumps
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Synaptic Transmission
• Hyperpolarization
– when axon is repolarizing, more K+ ions leave the cell, causing the cell to become MORE negative than before it started
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Synaptic Transmission
• All-or-None Principle
– a neuron will fire with its full intensity or not at all
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Synaptic Transmission
• Electrochemical Reaction
– Electrical within the neuron (impulse)
– Chemical between the neurons (neurotransmitters)
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The Brain
• Examining the Brain
• Structures of the Brain
• Hemispheric Specialization
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Studying the Brain
• Accidents & Case Studies
– When people acquire some sort of brain damage, psychologists learn about the functions of the brain
– Famous Example: Phineas Gage
• Tamping rod flew through his frontal lobe
• Frontal lobe research was furthered because of this new information
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Studying the Brain
• Lesions
– Destruction of brain tissue lets us know the function of that part of the brain
– Accidental or purposeful
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Studying the Brain
• Electroencephalography (EEG)
– creates image of brain wave activity by eliciting evoked potentials
– Function only
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Studying the Brain
• Positron Emission Tomography (PET)
– creates image which looks at glucose usage in the brain after injection of radioactive form of glucose
– Function only
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Studying the Brain
• Computerized Axial Tomography (CAT/ CT)
– provides image of brain structure including soft tissue and bones; specialized type of x-ray
– Structure only
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Examining the Brain
• Magnetic Resonance Imaging (MRI)
– uses magnetic fields in order to examine structure of brain tissues
– Structure only
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Examining the Brain
• Functional Magnetic Resonance Imaging (fMRI)
– brain imaging technique which provides information about both structure and function
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Examining the Brain
• Transcranial Magnetic Stimulation (TMS)
– Stimulation of areas of the brain using magnetic field to influence activity of neurons (to depolarize or hyperpolarize)
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Structures of the Brain
• Hindbrain– Brainstem
• Medulla – in charge of respiration,
blood pressure, heart rate
• Pons– helps relay sensory info.,
has a role in controlling arousal and dreaming
• Reticular Formation– controls awareness and
arousal
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Structures of the Brain
• Hindbrain
– Cerebellum
• coordinates motor control and maintains balance and posture
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Structures of the Brain
• Forebrain
– Thalamus
• sensory switchboard of the brain for all senses except olfaction
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Structures of the Brain
• Forebrain
– Limbic System
• Hippocampus
– converts info from STM to LTM
• Hypothalamus
– homeostasis, regulates hunger and thirst, and sexual behavior, controls pituitary gland
• Amygdala
– role in emotions, especially anger and fear
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Structures of the Brain
• Forebrain
– Cerebral Cortex - Association Areas
• Frontal Lobe
– personality, problem-solving, initiation, judgment, impulse & emotion control, speech (L)
• Temporal Lobe
– auditory perception, memory, facial recognition (R), language comprehension (L)
• Parietal Lobe
– spatial processing (R), math (L), sensory organization
• Occipital Lobe
– visual perception
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Structures of the Brain
• Forebrain
– Cerebral Cortex - Association Areas
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Structures of the Brain
• Forebrain
– Cerebral Cortex - Sensorimotor Areas
• Motor Cortex
– controls voluntary movement (frontal)
• Somatosensory Cortex
– skin sense, tactile sensation (parietal)
• Visual Cortex
– visual processing (occipital)
• Auditory Cortex
– Auditory processing (temporal)
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Structures of the Brain
• Forebrain
– Cerebral Cortex - Sensorimotor Areas
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Structures of the Brain
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Structures of the Brain
• Forebrain
– Cerebral Cortex – Language Areas
• Broca’s Area
– part of the frontal lobe on left side; controls the ability to form words
• Wernicke’s Area
– part of the temporal lobe on left side; controls the ability to comprehend language
• Angular Gyrus
– related to reading, turns visual symbols to auditory code
– Aphasia
• damage to area responsible for language
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Structures of the Brain
• Forebrain
– Cerebral Cortex – Language Areas
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Structures of the Brain
• Gyri vs. Sulci
– Gyrus
• peak in cerebral cortex
– Sulcus
• valley of cerebral cortex
– Wrinkles provide more surface area for cerebral cortex
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Structures of the Brain
• White vs. Grey Matter
– White Matter
• neural tissue containing mostly myelinated axons
• relays info. to cerebral cortex
– Grey Matter
• closely packed neuron cell bodies on the surface of the brain
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The Brain
• Corpus Callosum
– White matter structure which connects left and right hemispheres
– Allows communication between hemispheres
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Hemispheric Specialization
• Longitudinal Fissure
– separates left and right hemispheres
• Contralaterality
– one side of brain controls the other side of the brain
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Hemispheric Specialization
• Left vs. Right Brain
– Left
• analytical, speech (frontal), language comprehension (temporal), sequential, logical, interprets what is in right visual field (occipital), controls right side of body
– Right
• intuitive, holistic, language emphasis, facial recognition (temporal), spatial interpretation (Parietal), creativity, art, music appreciation, interprets what is in left visual field (occipital), controls left side of body
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Hemispheric Specialization
• Split Brain Research
– Michael Gazzaniga & Roger Sperry’s Research
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The Brain
• Brain Plasticity
– Ability for brain to make up for damage by having neurons of brain take on functions of damaged areas
– Age-dependent (doesn’t occur as well in older brains)
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Endocrine System
• Glands
• Hormones
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Glands
• Pineal Gland
– Produces melatonin (according to lightness or darkness of environment)
– Helps modulate sleep/wake cycle
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Glands
• Pituitary Gland– Produces Human Growth Hormone (HGH)
– Regulates homeostasis
– Regulates sexual development & functioning
– Contributes to physical growth
– Regulates water in the body
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Glands
• Thyroid Gland
– Produces Thyroxine
– Controls metabolism
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Glands
• Parathyroid Glands
– Regulate calcium levels in the body (remember, calcium is necessary for neurons to fire)
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Glands
• Adrenal Glands
– Produce noradrenaline, adrenaline and cortisol
– Regulate responses to stress and “fight or flight”
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Glands
• Pancreas
– Produces insulin and glucagon
– Regulates blood glucose level
– Aids in digestion
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Glands
• Ovaries
– Produce estrogen and progesterone
– Produce ova (eggs) for reproduction
– In charge of the production of secondary sex characteristics (i.e. breasts, hips)
– The female counterpart of the testes (male gonads)
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Glands
• Testes
– Produce testosterone
– Produce sperm for reproduction
– In charge of the production of secondary sex characteristics (i.e. facial hair, deep voice)
– The male counterpart of the ovaries (female gonads)
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Glands
• Hypothalamus
– Controls pituitary gland
– Secretes hormones related to hunger
– Link between the endocrine & nervous systems
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Hormones
• Melatonin
– Produced by the pineal gland
– Helps control sleep/wake cycle
– Production is inhibited by light and facilitated by dark
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Hormones
• Human Growth Hormone (HGH)
– Produced by the pituitary gland
– Stimulates growth and cell reproduction
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Hormones
• Adrenaline
– Aka epinephrine
– Produced by the adrenal glands
– Plays role in stress reactions & “fight or flight”
– Pumps body up (Sympathetic NS activity)
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Hormones
• Noradrenaline
– Aka norepinephrine
– Produced by the adrenal glands
– Plays role in stress reactions & “fight or flight”
– Pumps body up (Sympathetic NS activity)
– Also a neurotransmitter
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Hormones
• Cortisol
– Produced by the adrenals
– Released in stressful situations
– Involved in “fight or flight” response
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Hormones
• Insulin
– Produced in the pancreas
– Regulates glucose metabolism and blood glucose levels
– Released when blood glucose is elevated, decreases glucose level
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Hormones
• Glucagon
– Produced in the pancreas
– Released when blood glucose is low, increases glucose level
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Hormones
• Estrogen
– Produced by ovaries
– Primary female sex hormone
– Aids in sexual development and functioning
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Hormones
• Progesterone
– Produced by ovaries
– Involved with menstrual cycle and pregnancy
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Hormones
• Testosterone
– Produced by the testes
– Primary male sex hormone
– Aids in sexual development and functioning
– Linked to aggression
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Hormones
• Thyroxine
– Produced in thyroid
– Controls rate of bodily metabolic processes