Nephrology 3D Printing in Medicine and - Ramesh Hospitals · 5/3/2020 · Trends in Biotechnology...
Transcript of Nephrology 3D Printing in Medicine and - Ramesh Hospitals · 5/3/2020 · Trends in Biotechnology...
3D Printing in Medicine and Nephrology
Dr Ashutosh OjhaMBBS,MD,PDC(Nephrology)
MRCP(UK)I,FACP(USA)
Plan • Need • Aging and senescence • Organ dysfunction quantum• Organ sources ..cells in abundance• Methods to regenerate..an organ• Necessary ingredients• Organ reconstruction methods and challenges• Engineered organs care and longevity • Limitation• Recent Advances
Need
Need ….
Mech …Aging
Mech …Aging
Prevention of Aging
Cell conditioning
Advantages
• Small amount of own tissue used• Mostly harvestable sites• No antigenicity • No ethical issue
Disadvantages
• Organs with good and perennial nutrition available only can be used
• Scafolds needs to be bio-inert ….big challenge• Once transplanted the many organs age very
fast….compared to non organic ones• Metallic Heart valves last thrice the
bioprosthetic • Process time……6 months
Wayout….
• Tissue banking• Cytokines …..prepared by DNA recombinant
tech• Nutrient media research• Incubators • Sonicators • Fluroscopic analysis of media
Wayout….2..
• CAD scaffold designing • Tissue orientation • Scaffold repositioning • Tissue scavengers and enhancers
• ….commitment of you and me
There is a great hope of control of all neurodegenerative disorder……….85% of the age
related morbidity
Thank You• My slides are open …available