OBITUARY 597

1928 H. R. DEAN and R. A. WEBB. The determination of the rate of antibody

(precipitin) in rabbit’s blood by the method of ‘‘ optimal proportions ”. This Journal, 1928, 31, 89-99.

1930 H. R. DEAN, N. E. GOLDRWORTHY and C. TEN BROECK. The rate of disappear-

ance of injected horse serum from the blood of the rabbit. J . Immmol.,

Pathology as a biological science: an address at the dedication of the Institute of Pathology of Western Reserve University (U.S.A.), October 7th, 1929. Western Reserve Bull., No. 11, July lst, 1930.

1930, 18, 95-108.

1931 The precipitation reaction. In M.R.C. System of bacteriology, 1931, London,

VOI. 6, pp. 424-451. 1935

H. R. DEAN, G. L. TAYLOR and MURIEL E. ADAIR. The precipitin reaction. Experiments with an antiserum containing two antibodies. J . Hyg., Camb., 1935, 35, 69-74.

1936 H. R. DEAN, R. WILLIAMSON and 0. L. TAYLOR. Passive anaphylaxis following

the immediate injection of antigen after antiserum. J . Hyg., Camb., 1936, 36, 570-587.

1937 The reaction of isamine blue with serum. This Journal, 1937, 45, 745-771.

1941 Arthur Stanley Griffith (obituary). This Journal, 1941, 53, 311-312.

1944 H. R. DEAN and G. S. WILSON. William Whiteman Carlton Topley (obituary).

This Journal, 1944, 56, 451-464.

1946 George Lees Taylor (obituary). This Journal, 1946, 58, 593-594.

Neil Erneet a5olbeworthp 17th February 1897-26th September 1960

(PLATE CLXVI)

DR N. E. GOLDSWORTHY, Director of the Institute of Dental Research in Sydney, died after a short illness on 26th September 1960 at the age of 63. Dr Goldsworthy graduated M.B., Ch.M. at the University of Sydney in 1921 and spent the next three years as house physician and resident pathologist a t Sydney Hospital. He then proceeded to the London School of Hygiene and Tropical Medicine, where he was awarded the D.T.M.&H. in 1925. The next five years were spent a t

J. PATE. BACT.-VOL. 83: 1862) 2 P 2

598 NEIL ERNEST GOLDSWORTHY

Cambridge University, first as a Grocers Scholar and then as the John Lucas Walker Student. There he worked under the late Professor H. R. Dean, and in 1929-30 collaborated with H. W. Florey. His work a t Cambridge was chiefly concerned with the antigen-antibody reactions of precipitation and complement fixation. I n 1928 he was awarded the Ph.D. degree.

Returning to Sydney in 1930, Goldsworthy was appointed Senior Lecturer in Bacteriology in the University of Sydney under the late Professor H. D. Wright, and when Wright left Australia in 1934 Golds- worthy was acting-professor in the Department for the next twelve months. For the next few years he was able to combine his duties as senior lecturer with those of bacteriologist to the Royal North Shore Hospital, and in the war years he was acting director of the Kolling Research Institute in that hospital.

In the late 1930’s Goldsworthy’s interest turned towards the unsolved but fascinating problem of dental caries, which was ruining the teeth of his countrymen to an even greater degree than those of other civilised people. When the Institute of Dental Research in Sydney was formed a t the end of the war, it was fortunate to obtain as its first Director a man of Goldsworthy’s calibre, interested and already well-versed in dental problems. He held this post until his death, leading his team of research workers in work which was more fundamental than spectacular. I n the early years the Institute was cramped, but recently it has been housed in excellent laboratories, planned and equipped according to the wishes of the Director.

Goldsworthy was the author of numerous papers, and his scientific integrity shone through all of them. From the point of view of the outsider perhaps the most interesting contribution was his work on the teeth of the children in an orphanage near Sydney. The diet of these children could be really controlled, and it was shown that given the necessary dietary discipline it is possible to eliminate dental caries almost entirely. This work was reported in a series of important papers. Another long-term interest was the preventive value of fluoridation of water-supplies, and this interest was maintained through many frustrations by sincere but ill-informed opponents. His reputation extended outside Australia and in 1956 he was invited to attend the first Annual Conference on Diet and Dental Health a t the University of Alabama, U.S.A. Within Australia his pre-eminence in dental research was recognised by his appointment to the Advisory Committee of the National Health and Medical Research Council. This Committee advises on research grants, and Goldsworthy’s colleagues had great respect for his fairness and judgement.

I n general biology also the scientific community in New South Wales is under a debt to this man, because from 1932 until 1951, as its honorary secretary, he held the Society of Experimental Biology together. The debt was honoured by the establishment in 1955 of a t’riennial Goldsworthy Lecture, to be given b y a distinguished scientist.

J. PATH. Yxr-vor , . ti^

OBITUARY 599

Memorial lectures are comparatively common, but the Goldsworthy Lecture is unique in that it was established during his lifetime, as a mark of the regard in which he was held.

A shy and retiring man, Goldsworthy was more at home in the laboratory than in the arena,. His standards were high, in his conduct and in his loyalties as well as in his work. No one doubted his word, i t was so obvious that he was meticulous in his honesty. He had many friends, but if i t is true that we all live alone, Goldsworthy was more alone than most, owing to his innate shyness. Research was in his bones, and it is understandable that he was not so happy in the administrative side of his directorship, although of course always conscientious about administration. He often found it difficult to be philosophical about the attitude of officials who were sometimes more in sympathy with the idea than with the needs of research. A perfec- tionist ; yes, but such as he, although they do not achieve perfection, leave this imperfect world just a little better for their striving.

HUGH WARD.

BIBLIOGRAPHY

1925

Oase of hydatid infection involving the myocardium. Med. J . Austral., 1925, 1,110-111.

1928

Experiments upon the relationship of complement fixation to precipitation.

The precipitation test in hydatid infestation. This Journal, 1928, 31, 435-436. The occurrence of multiple zones in the serum precipitation reaction. This

This Journal, 1928, 31, 220-235.

Journal, 1928, 31, 525-539.

1930

H. R. DEAN, N. E. GOLDSWORTHY and C. TEN BROECK. The rate of disappearance of injected horse serum from the blood of the rabbit. J . Immunol., 1930,

Some properties of mucus, with special reference to its antibacterial functions. Brit. J . ESP. Path., 1930, 11, 192- 208.

18, 95-108. N. E. GOLDSWORTHY and H. FLOREY.

1934

Chondroma of the lung (Hamartoma chondromatoeum pulmonis). With report of a case. This Journal, 1934, 39, 291-298.

1935

N. E. GOLDSWORTHY and G. V. RUDD. zones in the precipitation reaction. This Journal, 1935, 40, 169-185.

N. E. GOLDSWORTHY and W. MOPPETT. membrane of the chick to certain physical and bacterial agents. Journal, 1935,41, 529-551.

Complexity of antigens in relation to

The reactions of the chorio-allantoio This

600 N E I L ERNEST GOLDSWORTHY

1936

N. E. GOLDSWORTHY and J. L. STILL. The effect of meat extract and other substances upon pigment production. This Journal, 1936, 43, 555-564.

PHYLLIS M. ANDERSON, N. E. GOLDSWORTHY and H. K. WARD. Some observa- tions on the relation between clinical types of diphtheria and cultural types of Corynebacterium diphtherice. Med. J . Austral., 1936, 2, 350-364.

W. MOPPETT and N. E. GOLDSWORTHY. A short investigation of the effect of “ Ensol ” upon transplantable mouse tumour. Med. J . Austral., 1936, 2, 75P755.

1937

Pulmonary actinomycosis caused by an acid-fast species of actinomyces. This Journal, 1937, 45, 17-27.

1938

Bacterium mtinomycetem comitans : a description of two strains. This Journal,

N. E. GOLDSWORTHY, J. L. STILL and J. A. DUMARESQ. Some sources of error in the interpretation of fermentation reactions, with special reference to the effects of serum enzymes. This Journal, 1938, 46, 253-260.

The effect of various meat extracts on pigment production by B. prodigiosus. This Journal, 1938, 46, 634-635.

Observations in diphtheria and the bacterial types of Corynebactcrium diphtherice. Med. J . Austral., 1938, 2,

1938, 46, 207-208.

N. E. GOLDSWORTHY and J. L. STILL.

H. WILSON and N. E. GOLDSWORTHY.

509-5 14.

1939

H. WILSON and N. E. GOLDSWORTHY. The use of blood agar for the identification of the types of C. diphtherice. This Journal, 1939, 48, 125-128.

H. R. SULLIVAN, J. L. STILL and N. E. GOLDSWORTHY. Acid-production as a basis for classifying lactobacilli from carious teeth. J . Dent. Res., 1939, 18,

H. R. SULLIVAN, J. S. HILL and N. E. GOLDSWORTHY. Some recent investiga- Proc. 10th Nat.

513-524.

tions into the Etiology of dental caries: a short review. Dent. Congr., 1939, pp. 275-286.

1940

H. R. SULLIVAN and N. E. GOLDSWORTHY. A comparat,ive study of anaerobic strains of Actinomyces from clinically normal mouths and from actinomycotic lesions. This Journal, 1940, 51, 253-261.

H. WILSON and N. E. GOLDSWORTHY. The Schick reaction: stabilized toxin compared with toxin diluted in saline solution. Med. J . Austral., 1940, 2, 403-405.

1942

N. E. GOLDSWORTHY and H. WILSON. The preparation of Loeffler’s medium This Journal, 1942, 54,

N. E. GOLDSWORTHY and H. K. WARD. Simple methods of staining Treponema

in relation to the morphology of C. diphtheria. 183-192.

pallidurn. This Journal, 1942. 54, 382-384.

1943

N. E. GOLDSWORTHY and H. WILSON. The Schick test in young adults. Med. J . Austral., 1943, 2, 349-353.

OBITUARY 601

1945 N. E. GOLDSWORTHY, F. SIMPSON and H. K. WARD. A slide modification of the

Eagle flocculation test. N e d . J . Austral., 1945, 2, 173-176.

1946

Australia and Science: the University of Sydney and scientists. Med. J . Austral., 1946, 1, 346-347.

1947

Actinomycosis, with special reference to the cervico-facial type. Dent. J .

1948

Austral., 1947, 19, 225-241.

R. LEMBERG, J. P. CALLAOHAN, D. E. TANDY and N. E. GOLDSWORTHY. Produc- tion of aminobenzoic acids by bacteria resistant t o sulphonamides. Austral. J . Exp. Biol. Med. Sci., 1948, 26, 9-27.

1950

B. LILrE”r.HAL and N. E. GOLDSWORTHY. Studies of the flora of the mouth. I. Yeast-like organisms: some morphological and physiological characters. Austral. J . Exp. Biol. Ned. Sci., 1950, 28, 261-269.

B. LILIENTHAL and N. E. GOLDSWORTHY. Studies of the flora of the mouth. 11. Yeast-like organisms: serological properties. Austral. J . Exp. Biol. Med. Sci., 1950, 28, 271-277.

BARBARA SINCLAIR, D. A. CAMERON and N. E. GOLDSWORTHY. Some observa- tions on dental conditions in Papua-New Guinea, 1947, with special reference to dental caries.

Dent. J . A.ustral., 1950, 22, 544-548. Dent. J . Austral., 1950, 22, 58-93 and 120-157.

Bacteriological problems of dental caries.

1952

F. A. E. LAWES, E. BEATRIX DURIE, N. E. GOLDSWORTHY and H. C. SPIES. Subacute bacterial endocarditis caused by Erysipelothrix rhusiopathim. Med. J . Austral., 1952, 1, 330-331.

1953

Observations on the use of fluorine for the partial control of dental caries. Med. J . Austral., 1953, 1, 281-285.

B. LILIENTHAL, N. E. GOLDSWORTHY, H. R. SULLIVAN and D. A. CAMERON. The biology of the children of Hopewood House, Bowral, New South Wales. I. Observations on dental caries extending over five years (1947-1952). Med. J . Austral., 1953, 1, 878-881 and Dent. J . Austral., 1953, 25, 163-168.

N. E. GOLDSWORTHY, BARBARA SINCLAIR and D. A. CAMERON. Some aspects of dental caries among native peoples of Papua-New Guinea and European inhabitants of Australia. Proc. 7th Pacific Science Congr., 1953,7,434-450.

1954

H. R. SULLIVAN and N. E. GOLDSWORTHY. A discussion of dietetic and nutri- tional factors in relation to dental caries and of difficulties in effecting changes in food habits. Med. J . Austral., 1954, 2, 136-139.

1955

N. E. GOLDSWORTHY, H. R. SULLIVAN and R. HARRIS. Practical caries control.

Genetics, environment and disease. Dent. J . Austral., 1955, 27, 45-59.

Dent. J . Austral., 1955, 27, 131-134.

602 N E I L ERNEST GOLDS WORTHY

1958 JENNIFER TAPLIN and N. E. GOLDSWORTEY. A study of 225 strains of Staphylococ-

Austral. J . Exp. Biol. Med. Sci., 1958, 36,

The biology of the children of Hopewood House, Bowral, N.S.W. 11. Observa- tions extending over five years (1952-1956 inclusive). 1. Introduction. Austral. Dent. J., 1958, 3, 309-310.

cus isolated from the mouth. 289-304.

1959 JENNIFER TAPLIN and N. E. GOLDSWORTHY. A comparison of strains of Staphy-

lococcus isolated from the mouth of two different groups of children. Med. J . Austral., 1959, 1, 259-263.

The lack of correlation between the prevalence of Staphylococcus spp. in saliva and dental caries experience in children. Austral. Dent. J. , 1959,4, 112-118.

Individuality. Austral. Dent. J., 1959, 4, 385-388.

1960 Every doctor a dietician. Med. J . Austral., 1960, 1, 285-286. Jugendmit gesunden Zahnen. Der Wendepunkt, 1960, 37, 483-488.