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UNIVERSIDADE FEDERAL DO RIO GRANDE DO SULINSTITUTO DE CINCIAS BSICAS DA SADE

PROGRAMA DE PS-GRADUAO EM CB:NEUROCINCIAS

NCP 00002 - CITOLOGIA E HISTOLOGIA DO SISTEMA NERVOSO

Responsvel: Profa. Matilde Achaval Elena

Carga Horria: 60 h

Crditos: 04 (quatro)

Ementa:

Neurnios. Compartimentos neuronais. Fibra nervosa. Sinapse. Mediadores. Neuroglia.Plexos corides. Barreiras do SN. Receptores e efetores. Medula espinhal e reasenceflicas.

Contedo ProgramticoNeurnios: soma e prolongamentos, estrutura, ultraestrutura e histofisiologia.Compartimentos neuronais.Fibra nervosa: tipos, fluxos, mielina, mielognese.Sinapse: tipos, zonas pr e ps-sinpticas.Mediadores clssicos e peptidrgicos, colocalizao e co-existncia; sntese, liberao,recaptao e degradao.

Neuroglia: astrcitos, oligodendrcitos, ependimcitos, microglia.Interrelao neurnio-glia.Plexos corides.Barreiras do sistema nervoso central e perifrico.Estrutura e ultraestrutura dos receptores e efetores.Anatomia microscpica da medula espinal e das reas enceflicas.

Bibliografia:

ALBERTS, B., BRAY, D., LEWIS, J., RAFF, M., ROBERTS, K., WATSON, J.D. Molecularbiology of the cell. 3.ed. New York: Garland Pub., 1994.BRADFORD, H.F. Chemical Neurobiology. New York: Freeman Co., 1985.

BRODAL, A. Anatomia Neurolgica. So Paulo: Roca, 1984.

COOPER, J.R., BLOOM, F.E., ROTH, R.H. The Biochemical Basis ofNeuropharmacology. Seventh Edition. New York: Oxford University Press, 1996.

CROSBY, E.C., HUMPREY, T., LAUER, E.W. Correlative Anatomy of the NervousSystem. New York: McMillan Co., 1962.

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ECCLES, J.C., ITO, M., SZENTGOTHAI, J. The Cerebellum as a Neuronal Machine.Berlin: Springer-Verlag, 1967.

FAWCETT, D. The Cell. Philadelphia: Saunders Co., 1981.

FIELDS, H.D. Pain. New York: McGraw-Hill, 1987.

KANDEL, E.R., SCHWARTZ, J.H., JESSELL, T.M. Essentials of Neural Science andBehavior. International Edition. London: Prentice-Hall International, 1995.

KANDEL, E.R., SCHWARTZ, J.H., JESSELL, T.M. Principles of Neural Science. 3. ed.New York: Prentice-Hall International, 1991.

KETENMANN, H., RANSOM, B.R. Neuroglia. New York: Oxford University Press, 1995.

NAUTA, W.J.H., FEIRTAG, M. Fundamental Neuroanatomy. New York: W.H. FreemanCo., 1986.NIEUWENHUYS, R. Chemoarchitecture of the Brain. New York: Springer-Verlag, 1985.

NICHOLLS, D.G. Proteins, Transmitters and Synapses. Oxford: Blackwell ScientificPublication, 1994.

OLSZEWSKI, J., BAXTER, D. Cytoarchitecture of the Human Brain Stem. New York:Springer-Verlag, 1954.

PARDRIDGE, W.M. The Blood-Brain Barrier. Cellular and Molecular Biology. New York:Raven Press, 1993.

PARENT, A. Carpenters Human Neuroanatomy. Ninth Edition. Baltimore: Williams &Wilkins, 1996.

PAXINOS, G., WATSON, C. The Rat Brain in Stereotaxic Coordinates. New York:Academic Press, 1986.

PAXINOS, G. The Rat Nervous System. Second Edition. New York: Academic Press,1995.

PETERS, A., PALAY, S.L., WEBSTER, H.F. The Fine Structure of the Nervous System.3.ed. Philadelphia: Saunders Co., 1991.

POLAK, J.M. Regulatory Peptides. Basel: Birkhauser Verlag, 1989.

RAMN Y CAJAL, S. Histology of the Nervous System. New York: Oxford UniversityPress, 1995. v.1 e 2.

SHEPHERD, G.M. Neurobiology. 3.ed. New York: Oxford University Press, 1994.

SIEGEL, G.J., AGRANOFF, B.W., MOLINOFF, P.B. Basic Neurochemistry. 5.ed. NewYork: Raven Press, 1993.

WALL, P.D., MELZACK, R. Texbook of Pain. Edinburgh: Churchill Livingstone, 1989.

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WEISS, L. Histology. Cell and Tissue Biology. New York: McMillan, 1983.

Artigos dos seguintes peridicos:

- Acta Anatomica - Journal of Neuroscience- Anatomical Record - Nature- Brain Research - Neuroscience- Brain Research Bulletin - Neuroscience Letters- Cell and Tissue Research - Progress in Brain Research- Experientia - Science- Journal Anatomy - Scientific American- Journal of Comparative Neurology - Trends in Neuroscience