Mutagens מוטגנים

Radiation קרינה

Chemical Agents כימיים חומרים

Mobile Genetic Elements אלמנטיםDNA ניידים

gal- , due to insertion OR “disruption”

REVERTANT: gal+ revertant, due to excision of IS1

Insertion elements: insertion elements as mutagens

(Ampicillin resistance)

Conservative

Replicative

Animation 13_Replicative transposition

Mutagens מוטגנים

Radiation קרינה

Chemical Agents כימיים חומרים

Mobile Genetic Elements אלמנטיםDNA ניידים

Inexact excission of IS1 can

also create gal-

(Ampicillin resistance)

50% of human genome is (dead) transposons/mobile elements!! 50% of human genome is (dead) transposons/mobile elements!!

Disruption, revertible