Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space...
Transcript of Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space...
![Page 1: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/1.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Musculoskeletal Physiology• Artificial gravity (from last lecture)!• Skeletal structures!• Bone chemistry!• Muscle physiology!• Muscle chemistry!• Exercise countermeasures
1
© 2015 David L. Akin - All rights reserved http://spacecraft.ssl.umd.edu
![Page 2: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/2.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Human Experience at Partial Gravity• Time on the Moon!
– Total time: 300 hours!– Longest single duration: 75 hours!– Microgravity time prior to landing: 3 days!
• Time on Mars!– Total time: 0!– Longest single duration: 0!– Microgravity time prior to landing: 180-260 days
2
![Page 3: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/3.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Critical Questions to be Answered• How does human physiological adaptation vary
with gravity level?!• Is there a minimum gravity level that results in
acceptable indefinite duration?!• What rotation rates are acceptable, and to which
population?!• How does routine variation of gravity level affect
human response?!• Do we need artificial gravity for transits to Mars?
3
![Page 4: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/4.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Issues with Prior Ground-Based Sims• Focus is on vestibular adaptation, rather than
gravitation-related physiology!• “Long-arm” centrifuges aren’t: most data was
collected with rotation radii ≤10 m!• “Long duration” typically hours, up to several days!• Some seminal research performed in non-articulated
habitats (faster rotation rates produce larger angles between gravity vector and perpendicular to floor)!
• All tests were at resultant gravity levels greater than 1g
4
![Page 5: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/5.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Rotating Station from 2001 (1968)
5
![Page 6: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/6.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
von Braun Orbital Station (1954)
6
![Page 7: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/7.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Internal Centrifuge from 2001
7
![Page 8: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/8.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Categories of Rotating Stations• Monolithic rotation!
– Entire habitat rotates!– Issues with docking, external systems!
• Partial system rotation!– Habitat portion of station/vehicle rotates!– Issues with integration, pass-throughs!
• Small arm rotation!– Rotation radius comparable to human height!– High gravitational gradient across body!– Proposed for beds, exercise equipment, etc.!– Not further considered here (“equipment”, not
“habitat”)
8
![Page 9: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/9.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Three Case Studies• Taken from output of University of Maryland
senior capstone classes in Spacecraft Design!– Clarke Station (2001)!– Space Station Phoenix (2006)!– Polus Station (2014)!
• Highly detailed publications available(http://spacecraft.ssl.umd.edu/academics/484.archives/484.archive_index.html)!
• All three systems intended to provide basic science data on human performance and adaptation to partial gravity levels
9
![Page 10: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/10.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Clarke Station (2001)• Inspired by NASA Gateway studies and arrival of
eponymous year of 2001: A Space Odyssey!• Located at Earth-Moon L1!• Capable of operating at all gravity levels between 0
and 1g!• Basic concept of operations:!
– Multiple 6-month missions at constant gravity levels!– Full-duration simulated opposition-class Mars mission!– (Same CONOPS will be adopted for all three case
studies)
10
![Page 11: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/11.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Clarke Station Configuration
11
![Page 12: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/12.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Space Station Phoenix (2006)• Concept was to reutilized International Space
Station components to perform artificial gravity studies rather than deorbit at end-of-life!
• Located in low Earth orbit!• ISS truss formed main structural element!• Additional structure designed to take rotating
gravity loads!• Inflated tunnels allow crew movement between
habitats!• Minimized new development and launch costs
12
![Page 13: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/13.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Space Station Phoenix Configuration
13
![Page 14: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/14.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Phoenix Reuse of ISS Components
14
![Page 15: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/15.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Polus Station• Modular evolutionary low-cost approach!
– Habitat in microgravity used to support extended exploration during Asteroid Redirect Mission (lunar distant retrograde orbit)!
– Add elements for rotation and perform six-month science studies at various gravity levels!
– Add elements for simulation and perform full-duration Mars simulated mission without resupply!
• Hard budget cap of $3B/year!• Limited to only one SLS-1b cargo launch per phase
15
![Page 16: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/16.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Polus Configuration (Phase 2)
16
![Page 17: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/17.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Basic Spin Parameters of Stations
17
Clarke Phoenix Polus
Spin Radius (m) 68 44 56
Earth spin rate (rpm) 3.62 4.5 4
Mars spin rate (rpm) 2.22 2.77 2.47
Moon spin rate (rpm) 1.45 1.8 1.6
![Page 18: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/18.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Program Comparisons
18
Clarke Phoenix Polus
System Mass 315 MT 254 MT* 126 MT
Launches 49 Delta IV H!6 Shuttle 16 Delta IV H
3 SLS!5 Falcon Heavy
Cost ($FY14) $66.1B $17.4B $20.7B
* Does not include 300 MT mass of ISS reuse components
![Page 19: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/19.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Discussion of Design Issues• Spin rate!• Coriolis acceleration!• Dynamic stability!• Mass and stiffness!• Spin up/spin down!• Crew habitat configurations!• Crew access!• Extravehicular activities!• Crew escape
19
![Page 20: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/20.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Spin Rate• Ground-based testing indicates that tolerance of
rotation rate varies from 1-10 rpm!– 1 rpm for sensitive groups (e.g., pregnant women)!– 10 rpm for limited group with stepwise acclimatization!
• Tolerance limit for 90% of the population probably 3-4 rpm
20
0.1$
1$
10$
1$ 10$ 100$ 1000$
Rota)o
n$Ra
te$(rpm
)$
Rota)on$Radius$(m)$
Moon$Mars$Earth$
![Page 21: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/21.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Coriolis Acceleration• Motion in spin direction causes change in apparent
vertical acceleration!• Motion in radial direction causes tangential
acceleration
21
0"
0.05"
0.1"
0.15"
0.2"
0.25"
0.3"
0" 1" 2" 3" 4" 5" 6" 7"
Corio
lis"Accelera5
on"(g's)"
Rota5on"Rate"(rpm)"
0.5"m/sec"1"m/sec"2"m/sec"
![Page 22: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/22.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Crew Habitat Configurations• Toroidal!
– Provides very large volume and floor area!– Massive (or very small toroid minor diameter)!
• Single floor!– Closer to consistent gravity conditions!– e.g., 8 m habitat on 50 m spin - max gravity error 0.3%
magnitude, 4.6° from vertical!
• Multiple floors!– Different gravity levels on each floor!– e.g., 50 m spin - 4% change in gravity per 2 m floor
22
![Page 23: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/23.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Intermodule Access• Habitats on different arms may require crew
transfer under spin!– Interpersonal dynamics for isolated teams!– Limited skill sets (e.g., doctors)!– Unique equipment and facilities!
• Pressurized tubes to spin axis !– Length=2r!– Work to climb to spin axis =!
• Pressurized circumferential transit tunnel!– Length= r - exceeds radial tunnels if angle>115°!– Requires cable bracing - radial and transverse
23
✓
mgnom
r
2
![Page 24: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/24.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Extravehicular Activity• Required on regular intervals for all habitats to
date!• ISS demonstrates need for near-term contingency
EVA capability!• EVA under spin is mountain climbing in a
spacesuit!• Potential mitigation strategies:!
– Maximize systems inside pressure hull!– Design gravity accommodations at all EVA sites (e.g.,
hoists, scaffolds, restraint systems)!– Budget propellant for regular and contingency spin
down/up cycles for maintenance
24
![Page 25: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/25.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Crew Rotation and Escape• Docking under spin only feasible along spin axis!
– May require despun docking adapter!– Problem with more than 1-2 spacecraft!– Spin axis is valuable territory (e.g., antennas, arrays)!
• Current policy is to always have means of safe escape/EDL for every crew!– Spacecraft docking adapters not designed for stress of
holding spacecraft under gravity loads!– Dramatic impact on both spacecraft and station due to
departure under spin!– Alternative is reliable access to axis under spin
25
![Page 26: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/26.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Human Factors of Live Under Spin• Acclimatization to variations in gravity level!
– Multiple floor habitats!– Routine access to/through hub!– Effect of short-period microgravity on physiology
studies of fractional gravity levels!
• Interacting with outside world!– Windows show rotating environment (sensory conflict)!– Effect of external illumination (sunlight through
windows sweeping through station every 15 seconds or so)
26
![Page 27: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/27.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Conclusions• Designing and operating a variable gravity habitat
is crucial for human risk mitigation prior to Mars mission!
• Stations can be created at reasonable cost and launch mass by adopting new technologies (e.g., active cable control)!
• While a rotating habitat will teach us critical issues about survival on Mars, we still don’t know everything we need to know about designing and operating rotating habitats
27
![Page 28: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/28.jpg)
Decompression/Neurovestibular Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
References• R. L. DeHart, ed., Fundamentals of Aerospace
Medicine, Second Edition Williams and Wilkins, 1996!
• A. E. Nicogossian, C. L. Huntoon, and S. L. Pool, Space Physiology and Medicine, Third Edition Lea and Febiger, 1994!
• A. E. Nicogossian, S. R. Mohler, O. G. Gazenko, and A. I. Grigoriev, eds., Space Biology and Medicine (Volume III, Book 1: Humans in Spaceflight) American Institute of Aeronautics and Astronautics, 1996!
28
![Page 29: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/29.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Skeletal Structure
29
from Lujan and White, Human Physiology in Space NASA/NIH/USRA/UTSW
![Page 30: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/30.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Categories of Articulated Joints
30
from Lujan and White, Human Physiology in Space NASA/NIH/USRA/UTSW
![Page 31: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/31.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Major Parts of a Long Bone
31
from Lujan and White, Human Physiology in Space NASA/NIH/USRA/UTSW
![Page 32: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/32.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Bone Construction and Maintenance• All bones start out cartilagenous!• Ossification - conversion of cartilage to bone!• Osteoblasts - deposit minerals and salts!• Osteoclasts - break down unused/damaged areas!• Rates of bone growth and harvesting driven by
stress on bone
32
![Page 33: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/33.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Basic Multicellular Unit in Bone Growth
33
from Churchill, Fundamentals of Space Life Sciences - Krieger Publishing, 1997
![Page 34: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/34.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Calcium Regulation System
34
from Lujan and White, Human Physiology in Space NASA/NIH/USRA/UTSW
![Page 35: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/35.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Skylab Early Urinary Calcium Output
35
from Churchill, Fundamentals of Space Life Sciences - Krieger Publishing, 1997
![Page 36: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/36.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Skylab Long-Duration Urine and Fecal Ca
36
![Page 37: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/37.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Bone Density - 5-6 Months on Mir
37
from Nicogossian et. al., Space Biology and Medicine - AIAA, 1996
![Page 38: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/38.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Efficacy of Countermeasures on Ca Loss
38
from Nicogossian et. al., Space Biology and Medicine - AIAA, 1996
![Page 39: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/39.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Functioning of Muscle Fiber
39
from Lujan and White, Human Physiology in Space NASA/NIH/USRA/UTSW
![Page 40: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/40.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Muscle Metabolism• Anaerobic!!!!
• Aerobic!!
• All conditions
40
ATP � ADP + P + free energy
creatine phosphate + ADP � creatine + ATP
glycogen or glucose + P + ADP � lactate + ATP
glycogen or fatty acids + P + ADP + O2 � CO2 + H2O + ATP
2ADP � ATP + AMP
![Page 41: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/41.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Energy Transfer Kinetics
41
from Johnson, Biomechanics and Exercise Physiology - John Wiley and Sons, 1991
![Page 42: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/42.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Changes in Muscle Fibers to Bed Rest
42
from Nicogossian et. al., Space Biology and Medicine - AIAA, 1996
![Page 43: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/43.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Long-Term Adaptation to Microgravity
43
from Nicogossian, Huntoon, and Pool, Space Physiology and Medicine - Lea and Fabiger, 1994
![Page 44: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/44.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Overall Body Response to Space Flight
44
from Lujan and White, Human Physiology in Space NASA/NIH/USRA/UTSW
![Page 45: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/45.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Current ISS Exercise Protocols
45
![Page 46: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/46.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Resistive Exercise Equipment on ISS
46
![Page 47: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/47.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
ARED Specs (vs. IRED)
47
![Page 48: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/48.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
ISS Exercise Equipment
48
![Page 49: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/49.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Nominal ARED Maintenance
49
![Page 50: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/50.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Experimental Download Harness
50
![Page 51: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/51.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Current Exercise Not Totally Effective
51
![Page 52: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/52.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
New Treadmill - C.O.L.B.E.R.T.
52
![Page 53: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/53.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
HRP Risks and Gaps
53
![Page 54: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/54.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Strategy for New Exercise Protocols
54
![Page 55: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/55.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Resistance Exercises - Weekly Schedule
55
![Page 56: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/56.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Aerobic Interval Schedule
56
![Page 57: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/57.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
Composite Weekly Schedule
57
![Page 58: Musculoskeletal Physiology - UMD · 2015. 2. 12. · Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support U N I V E R S I T Y O F MARYLAND Musculoskeletal Physiology](https://reader036.fdocuments.us/reader036/viewer/2022071415/6111b4f827abcc2a9e60dbbf/html5/thumbnails/58.jpg)
Musculoskeletal Physiology ENAE 697 - Space Human Factors and Life Support
U N I V E R S I T Y O FMARYLAND
References• R. L. DeHart, ed., Fundamentals of Aerospace Medicine,
Second Edition Williams and Wilkins, 1996!• A. E. Nicogossian, C. L. Huntoon, and S. L. Pool,
Space Physiology and Medicine, Third Edition Lea and Febiger, 1994!
• A. E. Nicogossian, S. R. Mohler, O. G. Gazenko, and A. I. Grigoriev, eds., Space Biology and Medicine (Volume III, Book 1: Humans in Spaceflight) American Institute of Aeronautics and Astronautics, 1996!
• J. T. Joiner, ed., NOAA Diving Manual: Diving for Science and Technology, Fourth Edition Best Publishing, 2001
58