Multiple sequence alignment
15
Multiple sequence alignment
-
Upload
malla-reddy-college-of-pharmacy -
Category
Education
-
view
292 -
download
1
Transcript of Multiple sequence alignment
Uses
•Pair-wise sequence alignment, Multiple sequence alignment Evolutionary relationships
•Multiple sequence alignment Information structural relationships Information on the most alike regionsPrediction of specific probes
Scoring gap penalties by the MSA
Natural gap cost: The sum of the no. of gaps in all pair-wise combinations
Quasi-natural gap cost: Natural cost + additional value for any gap that begins and ends within another